PuQing Yuan, PhD

Associate Researcher, Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen Department of Medicine at UCLA

Dr. P. Yuan explores the function of the CRF receptor signaling system in the gut as a local mediator of the dual gastric inhibitory and colonic stimulatory influence of stress. These studies aim to determine the expression of gastric and colonic CRF ligands and cognate receptors, their regulation at these sites under stress, and mechanisms underlying their dual local actions in the stomach and colon. The results of these studies may provide novel strategies for management of functional bowel disorders.