Please note the CURE Pilot and Feasibility application mechanism is a two step process. 

1. PFS Call for a letter of intent announced and submitted by the deadline.
2. The letter of intent will be reviewed and if selected, applicants will be asked to submit a full application.


Category 1. New investigators without current or past NIH or related agency research support (including career developmental awards) as principal investigators, who are seeking to establish their own independent research program.

Category 2. Established investigators with currently active research support, who have not been involved in research of the digestive system and who want to enter this field of research.

Category 3. Established investigators with currently active support for research in the digestive system, who want to pursue a new research direction in the field of gastroenterology, which represents a significant departure from their funded research.

Highly innovative proposals are encouraged. Category 1 is given preference.


  1. Applicants must hold a Ph.D., M.D. or equivalent degree and have at least 2 years of postgraduate research experience.
  2. Trainees who are recipient of an NRSA individual award (F32) or are supported by an institutional training grant (T32), or fellowship are eligible in their last year of training.
  3. Applicants must have a UCLA appointment in the academic track (research fellows are included) by the time of the award.
  4. New investigators without independent support need to provide documentation of support (i.e. space available and financial support beyond the PFS fund if awarded) of a UCLA or VA faculty sponsor.
  5. An investigator is eligible only once for PFS support with the exception of new investigators (category 1) whose previous PFS has resulted in independent funding and are now eligible to apply as category 3.
  6. Applicants are required to use at least one Center core in addition to the Administrative Core (see website for list of Cores and services at and perform research at CURE (VA or UCLA) and UCLA.
  7. Applications establishing collaborative interactions within the Center are encouraged.
  8. CTSI Reporting Requirements will be distributed at the time of the award notification.


LETTER of INTENT: A one-page letter of intent with the applicant’s NIH-style biosketch should be submitted as an e-mail attachment (all in one pdf document) to the program coordinator, Jacqueline Ismen ( The letter of intent should include 1) the category (see eligibility for the categories) for which the applicant wishes to apply, rank and department of the applicant, 2) the title, hypothesis and a paragraph describing the salient features of the project, 3) which core(s) of the CURE: DDRC will be used, and 4) the title of the mentor’s funded research, if the applicant is a junior investigator without independent funding, or of other funded projects, if the applicant is a senior investigator, and how the proposed project will differ from the funded projects. If the applicant is a PFS awardee who wishes to apply for a second year funding, a progress report of past supported research must be included for evaluation. Applicants will be notified of their eligibility to submit a full application.