Please find below CURE Publications, 1999-2016, divided by year and then author name:

                  Duboc H, Tolstanova G, Yuan PQ, Wu V, Kaji I, Biraud M, Akiba Y, Kaunitz J, Million M, Tache Y, Larauche M. Reduction of epithelial secretion in male rat distal colonic mucosa by bile acid receptor TGR5 agonist, INT-777: role of submucosal neurons. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 November;28(11):1663-1676. PubMed PMID: 27259385; PubMed Central PMCID: PMC5083223.

                  Orand A, Naliboff B, Gadd M, Shih W, Ju T, Presson AP, Mayer EA, Chang L. Corticotropin-releasing hormone receptor 1 (CRH-R1) polymorphisms are associated with irritable bowel syndrome and acoustic startle response. Psychoneuroendocrinology. 2016 November;73:133-141. PubMed PMID: 27497153; PubMed Central PMCID: PMC5048544.

                  Koon HW, Su B, Xu C, Mussatto CC, Tran DH, Lee EC, Ortiz C, Wang J, Lee JE, Ho S, Chen X, Kelly CP, Pothoulakis C. Probiotic Saccharomyces boulardii CNCM I-745 prevents outbreak-associated Clostridium difficile-associated cecal inflammation in hamsters. American journal of physiology. Gastrointestinal and liver physiology. 2016 October 1;311(4):G610-G623. PubMed PMID: 27514478; PubMed Central PMCID: PMC5142203.

                  Hoang-Yen Tran D, Hoang-Ngoc Tran D, Mattai SA, Sallam T, Ortiz C, Lee EC, Robbins L, Ho S, Lee JE, Fisseha E, Shieh C, Sideri A, Shih DQ, Fleshner P, McGovern DP, Vu M, Hing TC, Bakirtzi K, Cheng M, Su B, Law I, Karagiannides I, Targan SR, Gallo RL, Li Z, Koon HW. Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. International journal of obesity (2005). 2016 September;40(9):1424-34. PubMed PMID: 27163748; PubMed Central PMCID: PMC5014693.

                  Million M, Larauche M. Stress, sex, and the enteric nervous system. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 September;28(9):1283-9. PubMed PMID: 27561694; PubMed Central PMCID: PMC5003424.

                  Padua D, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih D, Iliopoulos D, Pothoulakis C. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. American journal of physiology. Gastrointestinal and liver physiology. 2016 September 1;311(3):G446-57. PubMed PMID: 27492330; PubMed Central PMCID: PMC5076004.

                  Wang J, Sinnett-Smith J, Stevens JV, Young SH, Rozengurt E. Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD). The Journal of biological chemistry. 2016 August 19;291(34):17988-8005. PubMed PMID: 27369082; PubMed Central PMCID: PMC5016186.

                  Park SH, Videlock EJ, Shih W, Presson AP, Mayer EA, Chang L. Adverse childhood experiences are associated with irritable bowel syndrome and gastrointestinal symptom severity. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 August;28(8):1252-60. PubMed PMID: 27061107; PubMed Central PMCID: PMC4956522.

                  Antonios JP, Soto H, Everson RG, Orpilla J, Moughon D, Shin N, Sedighim S, Yong WH, Li G, Cloughesy TF, Liau LM, Prins RM. PD-1 blockade enhances the vaccination-induced immune response in glioma. JCI insight. 2016 July 7;1(10). PubMed PMID: 27453950; PubMed Central PMCID: PMC4951098.

                  Khalil HA, Lei NY, Brinkley G, Scott A, Wang J, Kar UK, Jabaji ZB, Lewis M, Martín MG, Dunn JC, Stelzner MG. A novel culture system for adult porcine intestinal crypts. Cell and tissue research. 2016 July;365(1):123-34. PubMed PMID: 26928041; PubMed Central PMCID: PMC4919165.

                  Videlock EJ, Shih W, Adeyemo M, Mahurkar-Joshi S, Presson AP, Polytarchou C, Alberto M, Iliopoulos D, Mayer EA, Chang L. The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression. Psychoneuroendocrinology. 2016 July;69:67-76. PubMed PMID: 27038676; PubMed Central PMCID: PMC4977028.

                  Kaji I, Akiba Y, Konno K, Watanabe M, Kimura S, Iwanaga T, Kuri A, Iwamoto K, Kuwahara A, Kaunitz JD. Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon. The Journal of physiology. 2016 June 15;594(12):3339-52. PubMed PMID: 26854275; PubMed Central PMCID: PMC4908031.

                  Holschneider DP, Guo Y, Mayer EA, Wang Z. Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats. Neurobiology of stress. 2016 June 1;3:8-22. PubMed PMID: 26751119; PubMed Central PMCID: PMC4700548.

                  Padua D, Vu JP, Germano PM, Pisegna JR. The Role of Neuropeptides in Mouse Models of Colitis. Journal of molecular neuroscience : MN. 2016 June;59(2):203-10. PubMed PMID: 26646243; PubMed Central PMCID: PMC4884658.

                  Scott A, Rouch JD, Jabaji Z, Khalil HA, Solorzano S, Lewis M, Martín MG, Stelzner MG, Dunn JC. Long-term renewable human intestinal epithelial stem cells as monolayers: A potential for clinical use. Journal of pediatric surgery. 2016 June;51(6):995-1000. PubMed PMID: 26995514; PubMed Central PMCID: PMC4921284.

                  Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. 2016 June;159(6):1520-1527. PubMed PMID: 26847803; PubMed Central PMCID: PMC4856542.

                  Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. American journal of physiology. Gastrointestinal and liver physiology. 2016 June 1;310(11):G1124-37. PubMed PMID: 27151939; PubMed Central PMCID: PMC5005285.

                  Yu J, Liu SH, Sanchez R, Nemunaitis J, Rozengurt E, Brunicardi FC. PDX1 associated therapy in translational medicine. Annals of translational medicine. 2016 June;4(11):214. PubMed PMID: 27386488; PubMed Central PMCID: PMC4916355.

                  Bakirtzi K, Law IK, Xue X, Iliopoulos D, Shah YM, Pothoulakis C. Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling. Journal of immunology (Baltimore, Md. : 1950). 2016 May 15;196(10):4311-21. PubMed PMID: 27076683; PubMed Central PMCID: PMC4868643.

                  Deriu E, Boxx GM, He X, Pan C, Benavidez SD, Cen L, Rozengurt N, Shi W, Cheng G. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS pathogens. 2016 May;12(5):e1005572. PubMed PMID: 27149619; PubMed Central PMCID: PMC4858270.

                  Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Molecular cancer research : MCR. 2016 May;14(5):437-47. PubMed PMID: 26979711; PubMed Central PMCID: PMC4867256.

                  Vorvis C, Koutsioumpa M, Iliopoulos D. Developments in miRNA gene signaling pathways in pancreatic cancer. Future oncology (London, England). 2016 May;12(9):1135-50. PubMed PMID: 26984178; PubMed Central PMCID: PMC5551925.

                  Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Science translational medicine. 2016 April 13;8(334):334ra54. PubMed PMID: 27075628; PubMed Central PMCID: PMC4934679.

                  Ackerman AL, Jellison FC, Lee UJ, Bradesi S, Rodríguez LV. The Glt1 glutamate receptor mediates the establishment and perpetuation of chronic visceral pain in an animal model of stress-induced bladder hyperalgesia. American journal of physiology. Renal physiology. 2016 April 1;310(7):F628-F636. PubMed PMID: 26697981; PubMed Central PMCID: PMC5504462.

                  Gupta A, Labus J, Kilpatrick LA, Bonyadi M, Ashe-McNalley C, Heendeniya N, Bradesi S, Chang L, Mayer EA. Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females. Brain structure & function. 2016 April;221(3):1667-79. PubMed PMID: 25630611; PubMed Central PMCID: PMC4573367.

                  Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly. International journal of antimicrobial agents. 2016 April;47(4):289-96. PubMed PMID: 27013001; PubMed Central PMCID: PMC4833571.

                  Wang J, Han L, Sinnett-Smith J, Han LL, Stevens JV, Rozengurt N, Young SH, Rozengurt E. Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552. American journal of physiology. Cell physiology. 2016 April 1;310(7):C542-57. PubMed PMID: 26739494; PubMed Central PMCID: PMC4824155.

                  Yuan PQ, Wu SV, Pothoulakis C, Taché Y. Urocortins and CRF receptor type 2 variants in the male rat colon: gene expression and regulation by endotoxin and anti-inflammatory effect. American journal of physiology. Gastrointestinal and liver physiology. 2016 March 15;310(6):G387-98. PubMed PMID: 26744472; PubMed Central PMCID: PMC4796293.

                  Hertzer KM, Xu M, Moro A, Dawson DW, Du L, Li G, Chang HH, Stark AP, Jung X, Hines OJ, Eibl G. Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer. Pancreas. 2016 March;45(3):458-65. PubMed PMID: 26495779; PubMed Central PMCID: PMC4854638.

                  Mahurkar S, Polytarchou C, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 March;28(3):410-22. PubMed PMID: 26670691; PubMed Central PMCID: PMC4760882.

                  Law IK, Jensen D, Bunnett NW, Pothoulakis C. Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin. Scientific reports. 2016 February 23;6:22195. PubMed PMID: 26902265; PubMed Central PMCID: PMC4763298.

                  Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi K, Dulai GS, Machicado GA. Natural history of definitive diverticular hemorrhage based on stigmata of recent hemorrhage and colonoscopic Doppler blood flow monitoring for risk stratification and definitive hemostasis. Gastrointestinal endoscopy. 2016 February;83(2):416-23. PubMed PMID: 26227931; PubMed Central PMCID: PMC4715947.

                  Walwyn WM, Chen W, Kim H, Minasyan A, Ennes HS, McRoberts JA, Marvizón JC. Sustained Suppression of Hyperalgesia during Latent Sensitization by μ-, δ-, and κ-opioid receptors and α2A Adrenergic Receptors: Role of Constitutive Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2016 January 6;36(1):204-21. PubMed PMID: 26740662; PubMed Central PMCID: PMC4701961.

                  Birtolo C, Go VL, Ptasznik A, Eibl G, Pandol SJ. Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas. 2016 January;45(1):21-31. PubMed PMID: 26658038; PubMed Central PMCID: PMC4859755.

                  Camus M, Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi KA, Machicado GA, Dulai GS, Jensen ME, Gornbein JA. Comparison of Three Risk Scores to Predict Outcomes of Severe Lower Gastrointestinal Bleeding. Journal of clinical gastroenterology. 2016 January;50(1):52-8. PubMed PMID: 25599218; PubMed Central PMCID: PMC4504830.

                  Hoffman JM, Baritaki S, Ruiz JJ, Sideri A, Pothoulakis C. Corticotropin-Releasing Hormone Receptor 2 Signaling Promotes Mucosal Repair Responses after Colitis. The American journal of pathology. 2016 January;186(1):134-44. PubMed PMID: 26597886; PubMed Central PMCID: PMC4714033.

                  Hong JY, Naliboff B, Labus JS, Gupta A, Kilpatrick LA, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Mayer EA. Altered brain responses in subjects with irritable bowel syndrome during cued and uncued pain expectation. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 January;28(1):127-38. PubMed PMID: 26526698; PubMed Central PMCID: PMC4943658.

                  Jarcho JM, Feier NA, Labus JS, Naliboff B, Smith SR, Hong JY, Colloca L, Tillisch K, Mandelkern MA, Mayer EA, London ED. Placebo analgesia: Self-report measures and preliminary evidence of cortical dopamine release associated with placebo response. NeuroImage. Clinical. 2016;10:107-14. PubMed PMID: 26759785; PubMed Central PMCID: PMC4683423.

                  Jensen DM, Ohning GV, Kovacs TO, Ghassemi KA, Jutabha R, Dulai GS, Machicado GA. Doppler endoscopic probe as a guide to risk stratification and definitive hemostasis of peptic ulcer bleeding. Gastrointestinal endoscopy. 2016 January;83(1):129-36. PubMed PMID: 26318834; PubMed Central PMCID: PMC4691549.

                  Labus JS, Naliboff B, Kilpatrick L, Liu C, Ashe-McNalley C, dos Santos IR, Alaverdyan M, Woodworth D, Gupta A, Ellingson BM, Tillisch K, Mayer EA. Pain and Interoception Imaging Network (PAIN): A multimodal, multisite, brain-imaging repository for chronic somatic and visceral pain disorders. NeuroImage. 2016 January 1;124(Pt B):1232-7. PubMed PMID: 25902408; PubMed Central PMCID: PMC4627849.

                  Latorre R, Huynh J, Mazzoni M, Gupta A, Bonora E, Clavenzani P, Chang L, Mayer EA, De Giorgio R, Sternini C. Expression of the Bitter Taste Receptor, T2R38, in Enteroendocrine Cells of the Colonic Mucosa of Overweight/Obese vs. Lean Subjects. PloS one. 2016;11(2):e0147468. PubMed PMID: 26866366; PubMed Central PMCID: PMC4750998.

                  Moussaoui N, Larauche M, Biraud M, Molet J, Million M, Mayer E, Taché Y. Limited Nesting Stress Alters Maternal Behavior and In Vivo Intestinal Permeability in Male Wistar Pup Rats. PloS one. 2016;11(5):e0155037. PubMed PMID: 27149676; PubMed Central PMCID: PMC4858303.

                  Rouch JD, Scott A, Lei NY, Solorzano-Vargas RS, Wang J, Hanson EM, Kobayashi M, Lewis M, Stelzner MG, Dunn JC, Eckmann L, Martín MG. Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. PloS one. 2016;11(1):e0148216. PubMed PMID: 26820624; PubMed Central PMCID: PMC4731053.

                  Zhou G, Yu J, Wang A, Liu SH, Sinnett-Smith J, Wu J, Sanchez R, Nemunaitis J, Ricordi C, Rozengurt E, Brunicardi FC. Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma. Current molecular medicine. 2016;16(1):83-90. PubMed PMID: 26695692; PubMed Central PMCID: PMC4994969.

                  Vuong HE, Hardi CN, Barnes S, Brecha NC. Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 December 2;35(48):15955-70. PubMed PMID: 26631476; PubMed Central PMCID: PMC4666919.

                  Kilpatrick LA, Istrin JJ, Gupta A, Naliboff BD, Tillisch K, Labus JS, Mayer EA. Sex commonalities and differences in the relationship between resilient personality and the intrinsic connectivity of the salience and default mode networks. Biological psychology. 2015 December;112:107-15. PubMed PMID: 26440126; PubMed Central PMCID: PMC5012423.

                  Phan J, Benhammou JN, Pisegna JR. Gastric Hypersecretory States: Investigation and Management. Current treatment options in gastroenterology. 2015 December;13(4):386-97. PubMed PMID: 26342486; PubMed Central PMCID: PMC4633316.

                  Stark AP, Chang HH, Jung X, Moro A, Hertzer K, Xu M, Schmidt A, Hines OJ, Eibl G. E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice. Surgery. 2015 December;158(6):1564-72. PubMed PMID: 26297056; PubMed Central PMCID: PMC4637247.

                  Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of experimental medicine. 2015 November 16;212(12):2147-63. PubMed PMID: 26552708; PubMed Central PMCID: PMC4647265.

                  Chang HH, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G. Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1. American journal of physiology. Cell physiology. 2015 November 15;309(10):C639-49. PubMed PMID: 26310818; PubMed Central PMCID: PMC4652080.

                  Vu JP, Goyal D, Luong L, Oh S, Sandhu R, Norris J, Parsons W, Pisegna JR, Germano PM. PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin. American journal of physiology. Gastrointestinal and liver physiology. 2015 November 15;309(10):G816-25. PubMed PMID: 26336928; PubMed Central PMCID: PMC4652141.

                  Young SH, Rey O, Rozengurt E. Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: Impact of the highly conservative mutation Ser170Thr. Biochemical and biophysical research communications. 2015 November 6;467(1):1-6. PubMed PMID: 26431875; PubMed Central PMCID: PMC4613767.

                  Rodriguez JA, Huerta-Yepez S, Law IK, Baay-Guzman GJ, Tirado-Rodriguez B, Hoffman JM, Iliopoulos D, Hommes DW, Verspaget HW, Chang L, Pothoulakis C, Baritaki S. Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling. Cellular and molecular gastroenterology and hepatology. 2015 November 1;1(6):610-630. PubMed PMID: 26495412; PubMed Central PMCID: PMC4610032.

                  Vuong HE, Pérez de Sevilla Müller L, Hardi CN, McMahon DG, Brecha NC. Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines. Neuroscience. 2015 October 29;307:319-37. PubMed PMID: 26335381; PubMed Central PMCID: PMC4603663.

                  Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D. MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice. Gastroenterology. 2015 October;149(4):981-92.e11. PubMed PMID: 26055138; PubMed Central PMCID: PMC4584179.

                  Fang K, Sideri A, Law IK, Bakirtzi K, Polytarchou C, Iliopoulos D, Pothoulakis C. Identification of a novel substance P (SP)-neurokinin-1 receptor (NK-1R) microRNA-221-5p inflammatory network in human colonic epithelial cells. Cellular and molecular gastroenterology and hepatology. 2015 September 1;1(5):503-515. PubMed PMID: 26645045; PubMed Central PMCID: PMC4669978.

                  Hubbard CS, Hong J, Jiang Z, Ebrat B, Suyenobu B, Smith S, Heendeniya N, Naliboff BD, Tillisch K, Mayer EA, Labus JS. Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 September;27(9):1282-94. PubMed PMID: 26087779; PubMed Central PMCID: PMC4550526.

                  Cherukuri DP, Deignan JL, Das K, Grody WW, Herschman H. Instability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma. Molecular oncology. 2015 August;9(7):1252-8. PubMed PMID: 25817443; PubMed Central PMCID: PMC4523444.

                  Irimia A, Labus JS, Torgerson CM, Van Horn JD, Mayer EA. Altered viscerotopic cortical innervation in patients with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 August;27(8):1075-81. PubMed PMID: 25952540; PubMed Central PMCID: PMC4520752.

                  Kaunitz JD. The Discovery of PCR: ProCuRement of Divine Power. Digestive diseases and sciences. 2015 August;60(8):2230-1. PubMed PMID: 26077976; PubMed Central PMCID: PMC4501591.

                  Kobayashi M, Lei NY, Wang Q, Wu BM, Dunn JC. Orthogonally oriented scaffolds with aligned fibers for engineering intestinal smooth muscle. Biomaterials. 2015 August;61:75-84. PubMed PMID: 26001072; PubMed Central PMCID: PMC4464968.

                  Labus JS, Van Horn JD, Gupta A, Alaverdyan M, Torgerson C, Ashe-McNalley C, Irimia A, Hong JY, Naliboff B, Tillisch K, Mayer EA. Multivariate morphological brain signatures predict patients with chronic abdominal pain from healthy control subjects. Pain. 2015 August;156(8):1545-54. PubMed PMID: 25906347; PubMed Central PMCID: PMC4504800.

                  O'Mahony F, Wroblewski K, O'Byrne SM, Jiang H, Clerkin K, Benhammou J, Blaner WS, Beaven SW. Liver X receptors balance lipid stores in hepatic stellate cells through Rab18, a retinoid responsive lipid droplet protein. Hepatology (Baltimore, Md.). 2015 August;62(2):615-26. PubMed PMID: 25482505; PubMed Central PMCID: PMC4458237.

                  Tuominen I, Beaven SW. Intestinal farnesoid X receptor puts a fresh coat of wax on fatty liver. Hepatology (Baltimore, Md.). 2015 August;62(2):646-8. PubMed PMID: 25998695; PubMed Central PMCID: PMC4523235.

                  Law IK, Bakirtzi K, Polytarchou C, Oikonomopoulos A, Hommes D, Iliopoulos D, Pothoulakis C. Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis. Gut. 2015 July;64(7):1095-104. PubMed PMID: 25112884; PubMed Central PMCID: PMC4422787.

                  Lugea A, Waldron RT, Pandol SJ. Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2015 July;15(4 Suppl):S1-5. PubMed PMID: 25736240; PubMed Central PMCID: PMC4515411.

                  Stengel A, Karasawa H, Taché Y. The role of brain somatostatin receptor 2 in the regulation of feeding and drinking behavior. Hormones and behavior. 2015 July;73:15-22. PubMed PMID: 26026616; PubMed Central PMCID: PMC4546908.

                  Sanmiguel C, Gupta A, Mayer EA. Gut Microbiome and Obesity: A Plausible Explanation for Obesity. Current obesity reports. 2015 June;4(2):250-61. PubMed PMID: 26029487; PubMed Central PMCID: PMC4443745.

                  Vu JP, Larauche M, Flores M, Luong L, Norris J, Oh S, Liang LJ, Waschek J, Pisegna JR, Germano PM. Regulation of Appetite, Body Composition, and Metabolic Hormones by Vasoactive Intestinal Polypeptide (VIP). Journal of molecular neuroscience : MN. 2015 June;56(2):377-87. PubMed PMID: 25904310; PubMed Central PMCID: PMC4458420.

                  Gupta A, Rapkin AJ, Gill Z, Kilpatrick L, Fling C, Stains J, Masghati S, Tillisch K, Mayer EA, Labus JS. Disease-related differences in resting-state networks: a comparison between localized provoked vulvodynia, irritable bowel syndrome, and healthy control subjects. Pain. 2015 May;156(5):809-19. PubMed PMID: 25735001; PubMed Central PMCID: PMC4402252.

                  Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D. A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. Inflammatory bowel diseases. 2015 May;21(5):996-1005. PubMed PMID: 25738378; PubMed Central PMCID: PMC4402238.

                  Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JC, Martin MG, Lagasse E, Zhang L, Yu J. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Scientific reports. 2015 April 10;5:8566. PubMed PMID: 25858503; PubMed Central PMCID: PMC4392360.

                  Wu JX, Liu SH, Nemunaitis JJ, Brunicardi FC. Liposomal insulin promoter-thymidine kinase gene therapy followed by ganciclovir effectively ablates human pancreatic cancer in mice. Cancer letters. 2015 April 10;359(2):206-10. PubMed PMID: 25596375; PubMed Central PMCID: PMC4336837.

                  Akiba Y, Kaunitz JD, Million M. Peripheral corticotropin-releasing factor receptor type 2 activation increases colonic blood flow through nitric oxide pathway in rats. Digestive diseases and sciences. 2015 April;60(4):858-67. PubMed PMID: 25701320; PubMed Central PMCID: PMC4501405.

                  Anselmi L, Huynh J, Duraffourd C, Jaramillo I, Vegezzi G, Saccani F, Boschetti E, Brecha NC, De Giorgio R, Sternini C. Activation of μ opioid receptors modulates inflammation in acute experimental colitis. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 April;27(4):509-23. PubMed PMID: 25690069; PubMed Central PMCID: PMC4405133.

                  Liu Z, Sun F, Braun J, McGovern DP, Piantadosi S. Multilevel regularized regression for simultaneous taxa selection and network construction with metagenomic count data. Bioinformatics (Oxford, England). 2015 April 1;31(7):1067-74. PubMed PMID: 25416747; PubMed Central PMCID: PMC4382903.

                  Marvizon JC, Walwyn W, Minasyan A, Chen W, Taylor BK. Latent sensitization: a model for stress-sensitive chronic pain. Current protocols in neuroscience. 2015 April 1;71:9.50.1-14. PubMed PMID: 25829356; PubMed Central PMCID: PMC4532319.

                  Mayer EA, Gupta A, Kilpatrick LA, Hong JY. Imaging brain mechanisms in chronic visceral pain. Pain. 2015 April;156 Suppl 1:S50-63. PubMed PMID: 25789437; PubMed Central PMCID: PMC4428597.

                  Sideri A, Stavrakis D, Bowe C, Shih DQ, Fleshner P, Arsenescu V, Arsenescu R, Turner JR, Pothoulakis C, Karagiannides I. Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1. American journal of physiology. Gastrointestinal and liver physiology. 2015 April 1;308(7):G591-604. PubMed PMID: 25591865; PubMed Central PMCID: PMC4385897.

                  Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2. Molecular cancer therapeutics. 2015 April;14(4):1014-23. PubMed PMID: 25673820; PubMed Central PMCID: PMC4394038.

                  Tarling EJ, Ahn H, de Aguiar Vallim TQ. The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2. Arteriosclerosis, thrombosis, and vascular biology. 2015 April;35(4):787-95. PubMed PMID: 25593129; PubMed Central PMCID: PMC4376635.

                  Gukovsky I, Gukovskaya AS. Impaired autophagy triggers chronic pancreatitis: lessons from pancreas-specific atg5 knockout mice. Gastroenterology. 2015 March;148(3):501-5. PubMed PMID: 25613315; PubMed Central PMCID: PMC4443443.

                  Liu Y, Ji H, Zhang Y, Shen X, Gao F, He X, Li GA, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury. Journal of hepatology. 2015 March;62(3):563-72. PubMed PMID: 25450716; PubMed Central PMCID: PMC4336640.

                  Sakanaka T, Inoue T, Yorifuji N, Iguchi M, Fujiwara K, Narabayashi K, Kakimoto K, Nouda S, Okada T, Kuramoto T, Ishida K, Abe Y, Takeuchi T, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. The effects of a TGR5 agonist and a dipeptidyl peptidase IV inhibitor on dextran sulfate sodium-induced colitis in mice. Journal of gastroenterology and hepatology. 2015 March;30 Suppl 1:60-5. PubMed PMID: 25827806; PubMed Central PMCID: PMC4874188.

                  Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. The Journal of biological chemistry. 2015 February 27;290(9):5566-81. PubMed PMID: 25468909; PubMed Central PMCID: PMC4342471.

                  Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. Septin dynamics are essential for exocytosis. The Journal of biological chemistry. 2015 February 27;290(9):5280-97. PubMed PMID: 25575596; PubMed Central PMCID: PMC4342448.

                  Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell metabolism. 2015 February 3;21(2):334-46. PubMed PMID: 25651185; PubMed Central PMCID: PMC4349439.

                  de Aguiar Vallim TQ, Tarling EJ, Ahn H, Hagey LR, Romanoski CE, Lee RG, Graham MJ, Motohashi H, Yamamoto M, Edwards PA. MAFG is a transcriptional repressor of bile acid synthesis and metabolism. Cell metabolism. 2015 February 3;21(2):298-310. PubMed PMID: 25651182; PubMed Central PMCID: PMC4317590.

                  Bromley EG, May FP, Federer L, Spiegel BM, van Oijen MG. Explaining persistent under-use of colonoscopic cancer screening in African Americans: a systematic review. Preventive medicine. 2015 February;71:40-8. PubMed PMID: 25481094; PubMed Central PMCID: PMC4329030.

                  Kaji I, Iwanaga T, Watanabe M, Guth PH, Engel E, Kaunitz JD, Akiba Y. SCFA transport in rat duodenum. American journal of physiology. Gastrointestinal and liver physiology. 2015 February 1;308(3):G188-97. PubMed PMID: 25394661; PubMed Central PMCID: PMC4312951.

                  Nguyen AH, Toste PA, Farrell JJ, Clerkin BM, Williams J, Muthusamy VR, Watson RR, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Current recommendations for surveillance and surgery of intraductal papillary mucinous neoplasms may overlook some patients with cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2015 February;19(2):258-65. PubMed PMID: 25373706; PubMed Central PMCID: PMC4305480.

                  Tan YV, Abad C, Wang Y, Lopez R, Waschek J. VPAC2 (vasoactive intestinal peptide receptor type 2) receptor deficient mice develop exacerbated experimental autoimmune encephalomyelitis with increased Th1/Th17 and reduced Th2/Treg responses. Brain, behavior, and immunity. 2015 February;44:167-175. PubMed PMID: 25305591; PubMed Central PMCID: PMC4275378.

                  Taché Y, Million M. Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia. Journal of neurogastroenterology and motility. 2015 January 31;21(1):8-24. PubMed PMID: 25611064; PubMed Central PMCID: PMC4288101.

                  Coveleskie K, Gupta A, Kilpatrick LA, Mayer ED, Ashe-McNalley C, Stains J, Labus JS, Mayer EA. Altered functional connectivity within the central reward network in overweight and obese women. Nutrition & diabetes. 2015 January 19;5:e148. PubMed PMID: 25599560; PubMed Central PMCID: PMC4314578.

                  Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology. 2015 January 15;475:46-55. PubMed PMID: 25462345; PubMed Central PMCID: PMC4284078.

                  Abad C, Cheung-Lau G, Coûté-Monvoisin AC, Waschek JA. Vasoactive intestinal peptide-deficient mice exhibit reduced pathology in trinitrobenzene sulfonic acid-induced colitis. Neuroimmunomodulation. 2015;22(3):203-12. PubMed PMID: 25301381; PubMed Central PMCID: PMC4297532.

                  Bradesi S, Karagiannides I, Bakirtzi K, Joshi SM, Koukos G, Iliopoulos D, Pothoulakis C, Mayer EA. Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat. PloS one. 2015;10(7):e0130938. PubMed PMID: 26222740; PubMed Central PMCID: PMC4519289.

                  Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. Journal of Alzheimer's disease : JAD. 2015;43(3):967-76. PubMed PMID: 25125464; PubMed Central PMCID: PMC4258165.

                  Chen R, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM, Maitra A, Brentnall TA. Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. Laboratory investigation; a journal of technical methods and pathology. 2015 January;95(1):43-55. PubMed PMID: 25347153; PubMed Central PMCID: PMC4281293.

                  Cheng M, Ho S, Yoo JH, Tran DH, Bakirtzi K, Su B, Tran DH, Kubota Y, Ichikawa R, Koon HW. Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts. Clinical and experimental gastroenterology. 2015;8:13-29. PubMed PMID: 25565877; PubMed Central PMCID: PMC4274046.

                  Gupta A, Mayer EA, Sanmiguel CP, Van Horn JD, Woodworth D, Ellingson BM, Fling C, Love A, Tillisch K, Labus JS. Patterns of brain structural connectivity differentiate normal weight from overweight subjects. NeuroImage. Clinical. 2015;7:506-17. PubMed PMID: 25737959; PubMed Central PMCID: PMC4338207.

                  Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 January 1;21(1):157-65. PubMed PMID: 25348515; PubMed Central PMCID: PMC4286535.

                  Khalil HA, Lei NY, Nie W, Lewis MS, Stelzner MG, Martín MG, Dunn JC, Yoo J. Primary Myofibroblasts Maintain Short-Term Viability following Submucosal Injection in Syngeneic, Immune-Competent Mice Utilizing Murine Colonoscopy. PloS one. 2015;10(5):e0127258. PubMed PMID: 26016485; PubMed Central PMCID: PMC4445916.

                  Kutch JJ, Yani MS, Asavasopon S, Kirages DJ, Rana M, Cosand L, Labus JS, Kilpatrick LA, Ashe-McNalley C, Farmer MA, Johnson KA, Ness TJ, Deutsch G, Harris RE, Apkarian AV, Clauw DJ, Mackey SC, Mullins C, Mayer EA. Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study. NeuroImage. Clinical. 2015;8:493-502. PubMed PMID: 26106574; PubMed Central PMCID: PMC4474411.

                  Law IK, Pothoulakis C. MicroRNA-133α regulates neurotensin-associated colonic inflammation in colonic epithelial cells and experimental colitis. RNA & disease (Houston, Tex.). 2015;2(1). PubMed PMID: 26005712; PubMed Central PMCID: PMC4441413.

                  Li Y, Go VL, Sarkar FH. The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome. Pancreas. 2015 January;44(1):1-10. PubMed PMID: 25493373; PubMed Central PMCID: PMC4264839.

                  Martinez L, Ermolova NV, Ishikawa TO, Stout DB, Herschman HR, Spencer MJ. A reporter mouse for optical imaging of inflammation in mdx muscles. Skeletal muscle. 2015;5:15. PubMed PMID: 25949789; PubMed Central PMCID: PMC4422315.

                  Marzagalli R, Scuderi S, Drago F, Waschek JA, Castorina A. Emerging Role of PACAP as a New Potential Therapeutic Target in Major Diabetes Complications. International journal of endocrinology. 2015;2015:160928. PubMed PMID: 26074958; PubMed Central PMCID: PMC4446501.

                  McGowan I, Anton PA, Elliott J, Cranston RD, Duffill K, Althouse AD, Hawkins KL, De Rosa SC. Exploring the feasibility of multi-site flow cytometric processing of gut associated lymphoid tissue with centralized data analysis for multi-site clinical trials. PloS one. 2015;10(5):e0126454. PubMed PMID: 26010577; PubMed Central PMCID: PMC4444258.

                  Mulak A, Larauche M, Biraud M, Million M, Rivier J, Taché Y. Selective agonists of somatostatin receptor subtype 1 or 2 injected peripherally induce antihyperalgesic effect in two models of visceral hypersensitivity in mice. Peptides. 2015 January;63:71-80. PubMed PMID: 25451334; PubMed Central PMCID: PMC4385413.

                  Orand A, Gupta A, Shih W, Presson AP, Hammer C, Niesler B, Heendeniya N, Mayer EA, Chang L. Catecholaminergic Gene Polymorphisms Are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome. PloS one. 2015;10(8):e0135910. PubMed PMID: 26288143; PubMed Central PMCID: PMC4546052.

                  Taché Y. Corticotrophin-releasing factor 1 activation in the central amygdale and visceral hyperalgesia. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 January;27(1):1-6. PubMed PMID: 25557223; PubMed Central PMCID: PMC4389773.

                  Wang L, Mogami S, Yakabi S, Karasawa H, Yamada C, Yakabi K, Hattori T, Taché Y. Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito. PloS one. 2015;10(9):e0139325. PubMed PMID: 26421719; PubMed Central PMCID: PMC4589401.

                  Wang Y, Yan C, Liu L, Wang W, Du H, Fan W, Lutfy K, Jiang M, Friedman TC, Liu Y. 11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue. American journal of physiology. Endocrinology and metabolism. 2015 January 1;308(1):E84-95. PubMed PMID: 25389364; PubMed Central PMCID: PMC4281684.

                  Yoo JH, Ho S, Tran DH, Cheng M, Bakirtzi K, Kukota Y, Ichikawa R, Su B, Tran DH, Hing TC, Chang I, Shih DQ, Issacson RE, Gallo RL, Fiocchi C, Pothoulakis C, Koon HW. Anti-fibrogenic effects of the anti-microbial peptide cathelicidin in murine colitis-associated fibrosis. Cellular and molecular gastroenterology and hepatology. 2015 January;1(1):55-74.e1. PubMed PMID: 25729764; PubMed Central PMCID: PMC4338438.

                  Zhu J, Lu T, Yue S, Shen X, Gao F, Busuttil RW, Kupiec-Weglinski JW, Xia Q, Zhai Y. Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation. Transplantation. 2015 January;99(1):48-55. PubMed PMID: 25340604; PubMed Central PMCID: PMC4272660.

                  Akiba Y, Kaunitz JD. Prostaglandin pathways in duodenal chemosensing. Journal of gastroenterology and hepatology. 2014 December;29 Suppl 4:93-8. PubMed PMID: 25521740; PubMed Central PMCID: PMC4451058.

                  Bagarinao E, Johnson KA, Martucci KT, Ichesco E, Farmer MA, Labus J, Ness TJ, Harris R, Deutsch G, Apkarian AV, Mayer EA, Clauw DJ, Mackey S. Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network study. Pain. 2014 December;155(12):2502-9. PubMed PMID: 25242566; PubMed Central PMCID: PMC4504202.

                  Buzzanco A, Gomez A, Rodriguez E, French BA, Tillman BA, Chang S, Ganapathy E, Junrungsee S, Zarrinpar A, Agopian VG, Naini BV, French SW Jr, French SW Sr. Digital quantitation of HCC-associated stem cell markers and protein quality control factors using tissue arrays of human liver sections. Experimental and molecular pathology. 2014 December;97(3):399-410. PubMed PMID: 25218810; PubMed Central PMCID: PMC4262606.

                  Donahue TR, Nguyen AH, Moughan J, Li L, Tatishchev S, Toste P, Farrell JJ. Stromal microRNA-21 levels predict response to 5-fluorouracil in patients with pancreatic cancer. Journal of surgical oncology. 2014 December;110(8):952-9. PubMed PMID: 25132574; PubMed Central PMCID: PMC4232442.

                  Ji H, Liu Y, Zhang Y, Shen XD, Gao F, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. T-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury. Hepatology (Baltimore, Md.). 2014 December;60(6):2052-2064. PubMed PMID: 25066922; PubMed Central PMCID: PMC4396987.

                  Karasawa H, Pietra C, Giuliano C, Garcia-Rubio S, Xu X, Yakabi S, Taché Y, Wang L. New ghrelin agonist, HM01 alleviates constipation and L-dopa-delayed gastric emptying in 6-hydroxydopamine rat model of Parkinson's disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 December;26(12):1771-82. PubMed PMID: 25327342; PubMed Central PMCID: PMC4457321.

                  Stengel A, Taché Y. Brain peptides and the modulation of postoperative gastric ileus. Current opinion in pharmacology. 2014 December;19:31-7. PubMed PMID: 24999843; PubMed Central PMCID: PMC4254047.

                  Wagner JP, Sullins VF, Dunn JC. Skin-derived precursors generate enteric-type neurons in aganglionic jejunum. Journal of pediatric surgery. 2014 December;49(12):1809-14. PubMed PMID: 25487489; PubMed Central PMCID: PMC4261145.

                  Wagner JP, Sullins VF, Khalil HA, Dunn JC. A durable model of Hirschsprung's colon. Journal of pediatric surgery. 2014 December;49(12):1804-8. PubMed PMID: 25487488; PubMed Central PMCID: PMC4261142.

                  Hong C, Marshall SM, McDaniel AL, Graham M, Layne JD, Cai L, Scotti E, Boyadjian R, Kim J, Chamberlain BT, Tangirala RK, Jung ME, Fong L, Lee R, Young SG, Temel RE, Tontonoz P. The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice. Cell metabolism. 2014 November 4;20(5):910-8. PubMed PMID: 25440061; PubMed Central PMCID: PMC4261644.

                  Tong M, Jacobs JP, McHardy IH, Braun J. Sampling of intestinal microbiota and targeted amplification of bacterial 16S rRNA genes for microbial ecologic analysis. Current protocols in immunology. 2014 November 3;107:7.41.1-11. PubMed PMID: 25367129; PubMed Central PMCID: PMC4457454.

                  Balaji K, French CT, Miller JF, Colicelli J. The RAB5-GEF function of RIN1 regulates multiple steps during Listeria monocytogenes infection. Traffic (Copenhagen, Denmark). 2014 November;15(11):1206-18. PubMed PMID: 25082076; PubMed Central PMCID: PMC4282165.

                  Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR. Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. Molecular cancer research : MCR. 2014 November;12(11):1677-88. PubMed PMID: 25063587; PubMed Central PMCID: PMC4233191.

                  Rozengurt E, Soares HP, Sinnet-Smith J. Suppression of feedback loops mediated by PI3K/mTOR induces multiple overactivation of compensatory pathways: an unintended consequence leading to drug resistance. Molecular cancer therapeutics. 2014 November;13(11):2477-88. PubMed PMID: 25323681; PubMed Central PMCID: PMC4222988.

                  Shih DQ, Zheng L, Zhang X, Zhang H, Kanazawa Y, Ichikawa R, Wallace KL, Chen J, Pothoulakis C, Koon HW, Targan SR. Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis. Mucosal immunology. 2014 November;7(6):1492-503. PubMed PMID: 24850426; PubMed Central PMCID: PMC4205266.

                  Spiegel BM, Hays RD, Bolus R, Melmed GY, Chang L, Whitman C, Khanna PP, Paz SH, Hays T, Reise S, Khanna D. Development of the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) gastrointestinal symptom scales. The American journal of gastroenterology. 2014 November;109(11):1804-14. PubMed PMID: 25199473; PubMed Central PMCID: PMC4285435.

                  Hong JY, Kilpatrick LA, Labus JS, Gupta A, Katibian D, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Naliboff B, Mayer EA. Sex and disease-related alterations of anterior insula functional connectivity in chronic abdominal pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 October 22;34(43):14252-9. PubMed PMID: 25339739; PubMed Central PMCID: PMC4205551.

                  Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Molecular cancer therapeutics. 2014 October;13(10):2303-14. PubMed PMID: 25082960; PubMed Central PMCID: PMC4188417.

                  Itoh Y, Arnold AP. X chromosome regulation of autosomal gene expression in bovine blastocysts. Chromosoma. 2014 October;123(5):481-9. PubMed PMID: 24817096; PubMed Central PMCID: PMC4170013.

                  Ruegger PM, Clark RT, Weger JR, Braun J, Borneman J. Improved resolution of bacteria by high throughput sequence analysis of the rRNA internal transcribed spacer. Journal of microbiological methods. 2014 October;105:82-7. PubMed PMID: 25034229; PubMed Central PMCID: PMC4160368.

                  Arnold AP. Conceptual frameworks and mouse models for studying sex differences in physiology and disease: why compensation changes the game. Experimental neurology. 2014 September;259:2-9. PubMed PMID: 24509348; PubMed Central PMCID: PMC4125548.

                  Im E, Jung J, Pothoulakis C, Rhee SH. Disruption of Pten speeds onset and increases severity of spontaneous colitis in Il10(-/-) mice. Gastroenterology. 2014 September;147(3):667-679.e10. PubMed PMID: 24882466; PubMed Central PMCID: PMC4143453.

                  Liu Y, Yuan J, Tan T, Jia W, Lugea A, Mareninova O, Waldron RT, Pandol SJ. Genetic inhibition of protein kinase Cε attenuates necrosis in experimental pancreatitis. American journal of physiology. Gastrointestinal and liver physiology. 2014 September 1;307(5):G550-63. PubMed PMID: 25035113; PubMed Central PMCID: PMC4154116.

                  Costes S, Butler PC. Insulin-degrading enzyme inhibition, a novel therapy for type 2 diabetes?. Cell metabolism. 2014 August 5;20(2):201-3. PubMed PMID: 25100059; PubMed Central PMCID: PMC4144405.

                  Calkin AC, Lee SD, Kim J, Van Stijn CM, Wu XH, Lusis AJ, Hong C, Tangirala RI, Tontonoz P. Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in mice. Circulation research. 2014 August 1;115(4):442-9. PubMed PMID: 24935961; PubMed Central PMCID: PMC4119488.

                  Koon HW, Ho S, Hing TC, Cheng M, Chen X, Ichikawa Y, Kelly CP, Pothoulakis C. Fidaxomicin inhibits Clostridium difficile toxin A-mediated enteritis in the mouse ileum. Antimicrobial agents and chemotherapy. 2014 August;58(8):4642-50. PubMed PMID: 24890583; PubMed Central PMCID: PMC4135997.

                  Ngun TC, Ghahramani NM, Creek MM, Williams-Burris SM, Barseghyan H, Itoh Y, Sánchez FJ, McClusky R, Sinsheimer JS, Arnold AP, Vilain E. Feminized behavior and brain gene expression in a novel mouse model of Klinefelter Syndrome. Archives of sexual behavior. 2014 August;43(6):1043-57. PubMed PMID: 24923877; PubMed Central PMCID: PMC4371776.

                  Viitasalo L, Niemi L, Ashorn M, Ashorn S, Braun J, Huhtala H, Collin P, Mäki M, Kaukinen K, Kurppa K, Iltanen S. Early microbial markers of celiac disease. Journal of clinical gastroenterology. 2014 August;48(7):620-4. PubMed PMID: 24518796; PubMed Central PMCID: PMC4082475.

                  Karasawa H, Yakabi S, Wang L, Taché Y. Orexin-1 receptor mediates the increased food and water intake induced by intracerebroventricular injection of the stable somatostatin pan-agonist, ODT8-SST in rats. Neuroscience letters. 2014 July 25;576:88-92. PubMed PMID: 24915296; PubMed Central PMCID: PMC4096604.

                  Lin L, Ma C, Wei B, Aziz N, Rajalingam R, Yusung S, Erlich HA, Trachtenberg EA, Targan SR, McGovern DP, Heath JR, Braun J. Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function. Journal of immunology (Baltimore, Md. : 1950). 2014 July 15;193(2):940-9. PubMed PMID: 24935928; PubMed Central PMCID: PMC4096688.

                  Gupta A, Kilpatrick L, Labus J, Tillisch K, Braun A, Hong JY, Ashe-McNalley C, Naliboff B, Mayer EA. Early adverse life events and resting state neural networks in patients with chronic abdominal pain: evidence for sex differences. Psychosomatic medicine. 2014 July;76(6):404-12. PubMed PMID: 25003944; PubMed Central PMCID: PMC4113723.

                  Inoue T, Higashiyama M, Kaji I, Rudenkyy S, Higuchi K, Guth PH, Engel E, Kaunitz JD, Akiba Y. Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats. Digestive diseases and sciences. 2014 June;59(6):1286-95. PubMed PMID: 24379150; PubMed Central PMCID: PMC4196264.

                  Sallam T, Ito A, Rong X, Kim J, van Stijn C, Chamberlain BT, Jung ME, Chao LC, Jones M, Gilliland T, Wu X, Su GL, Tangirala RK, Tontonoz P, Hong C. The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis. Journal of lipid research. 2014 June;55(6):1120-30. PubMed PMID: 24671012; PubMed Central PMCID: PMC4031943.

                  Chen W, McRoberts JA, Marvizón JC. μ-Opioid receptor inhibition of substance P release from primary afferents disappears in neuropathic pain but not inflammatory pain. Neuroscience. 2014 May 16;267:67-82. PubMed PMID: 24583035; PubMed Central PMCID: PMC3998911.

                  Sinnett-Smith J, Ni Y, Wang J, Ming M, Young SH, Rozengurt E. Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling. American journal of physiology. Cell physiology. 2014 May 15;306(10):C961-71. PubMed PMID: 24647541; PubMed Central PMCID: PMC4024715.

                  Chen W, Walwyn W, Ennes HS, Kim H, McRoberts JA, Marvizón JC. BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals. The European journal of neuroscience. 2014 May;39(9):1439-54. PubMed PMID: 24611998; PubMed Central PMCID: PMC4122572.

                  Kilpatrick LA, Coveleskie K, Connolly L, Labus JS, Ebrat B, Stains J, Jiang Z, Suyenobu BY, Raybould HE, Tillisch K, Mayer EA. Influence of sucrose ingestion on brainstem and hypothalamic intrinsic oscillations in lean and obese women. Gastroenterology. 2014 May;146(5):1212-21. PubMed PMID: 24480616; PubMed Central PMCID: PMC4113508.

                  Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle. Virology. 2014 April;454-455:118-27. PubMed PMID: 24725938; PubMed Central PMCID: PMC4011396.

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                  Gong J, Robbins LA, Lugea A, Waldron RT, Jeon CY, Pandol SJ. Diabetes, pancreatic cancer, and metformin therapy. Frontiers in physiology. 2014;5:426. PubMed PMID: 25426078; PubMed Central PMCID: PMC4224068.

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                  Labus JS, Dinov ID, Jiang Z, Ashe-McNalley C, Zamanyan A, Shi Y, Hong JY, Gupta A, Tillisch K, Ebrat B, Hobel S, Gutman BA, Joshi S, Thompson PM, Toga AW, Mayer EA. Irritable bowel syndrome in female patients is associated with alterations in structural brain networks. Pain. 2014 January;155(1):137-49. PubMed PMID: 24076048; PubMed Central PMCID: PMC4100785.

                  Lei NY, Jabaji Z, Wang J, Joshi VS, Brinkley GJ, Khalil H, Wang F, Jaroszewicz A, Pellegrini M, Li L, Lewis M, Stelzner M, Dunn JC, Martín MG. Intestinal subepithelial myofibroblasts support the growth of intestinal epithelial stem cells. PloS one. 2014;9(1):e84651. PubMed PMID: 24400106; PubMed Central PMCID: PMC3882257.

                  Lu QY, Zhang L, Eibl G, Go VL. Overestimation of flavonoid aglycones as a result of the ex vivo deconjugation of glucuronides by the tissue β-glucuronidase. Journal of pharmaceutical and biomedical analysis. 2014 January;88:364-9. PubMed PMID: 24176739; PubMed Central PMCID: PMC3882034.

                  Ming M, Sinnett-Smith J, Wang J, Soares HP, Young SH, Eibl G, Rozengurt E. Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. PloS one. 2014;9(12):e114573. PubMed PMID: 25493642; PubMed Central PMCID: PMC4262417.

                  Richardson-Harman N, Hendrix CW, Bumpus NN, Mauck C, Cranston RD, Yang K, Elliott J, Tanner K, McGowan I, Kashuba A, Anton PA. Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study. PloS one. 2014;9(10):e111507. PubMed PMID: 25350130; PubMed Central PMCID: PMC4211741.

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                  Stengel A, Taché Y. CRF and urocortin peptides as modulators of energy balance and feeding behavior during stress. Frontiers in neuroscience. 2014;8:52. PubMed PMID: 24672423; PubMed Central PMCID: PMC3957495.

                  Su AM, Shih W, Presson AP, Chang L. Characterization of symptoms in irritable bowel syndrome with mixed bowel habit pattern. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 January;26(1):36-45. PubMed PMID: 23991913; PubMed Central PMCID: PMC3865067.

                  Vegezzi G, Anselmi L, Huynh J, Barocelli E, Rozengurt E, Raybould H, Sternini C. Diet-induced regulation of bitter taste receptor subtypes in the mouse gastrointestinal tract. PloS one. 2014;9(9):e107732. PubMed PMID: 25238152; PubMed Central PMCID: PMC4169553.

                  Vu JP, Million M, Larauche M, Luong L, Norris J, Waschek JA, Pothoulakis C, Pisegna JR, Germano PM. Inhibition of vasoactive intestinal polypeptide (VIP) induces resistance to dextran sodium sulfate (DSS)-induced colitis in mice. Journal of molecular neuroscience : MN. 2014 January;52(1):37-47. PubMed PMID: 24395090; PubMed Central PMCID: PMC4114158.

                  Zhou G, Sinnett-Smith J, Liu SH, Yu J, Wu J, Sanchez R, Pandol SJ, Abrol R, Nemunaitis J, Rozengurt E, Brunicardi FC. Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin. Frontiers in physiology. 2014;5:226. PubMed PMID: 25009500; PubMed Central PMCID: PMC4069483.

                  Ke B, Shen XD, Zhang Y, Ji H, Gao F, Yue S, Kamo N, Zhai Y, Yamamoto M, Busuttil RW, Kupiec-Weglinski JW. KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants. Journal of hepatology. 2013 December;59(6):1200-7. PubMed PMID: 23867319; PubMed Central PMCID: PMC4524560.

                  Marcus EA, Vagin O, Tokhtaeva E, Sachs G, Scott DR. Helicobacter pylori impedes acid-induced tightening of gastric epithelial junctions. American journal of physiology. Gastrointestinal and liver physiology. 2013 November 15;305(10):G731-9. PubMed PMID: 23989011; PubMed Central PMCID: PMC3840231.

                  Cheng P, Shih W, Alberto M, Presson AP, Licudine A, Mayer EA, Naliboff BD, Chang L. Autonomic response to a visceral stressor is dysregulated in irritable bowel syndrome and correlates with duration of disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2013 October;25(10):e650-9. PubMed PMID: 23822743; PubMed Central PMCID: PMC3788031.

                  Dawson DW, Hertzer K, Moro A, Donald G, Chang HH, Go VL, Pandol SJ, Lugea A, Gukovskaya AS, Li G, Hines OJ, Rozengurt E, Eibl G. High-fat, high-calorie diet promotes early pancreatic neoplasia in the conditional KrasG12D mouse model. Cancer prevention research (Philadelphia, Pa.). 2013 October;6(10):1064-73. PubMed PMID: 23943783; PubMed Central PMCID: PMC3835151.

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                  Kisfalvi K, Moro A, Sinnett-Smith J, Eibl G, Rozengurt E. Metformin inhibits the growth of human pancreatic cancer xenografts. Pancreas. 2013 July;42(5):781-5. PubMed PMID: 23462329; PubMed Central PMCID: PMC3681894.

                  Sinnett-Smith J, Kisfalvi K, Kui R, Rozengurt E. Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK. Biochemical and biophysical research communications. 2013 January 4;430(1):352-7. PubMed PMID: 23159620; PubMed Central PMCID: PMC3545113.

                  Waldron RT, Innamorati G, Torres-Marquez ME, Sinnett-Smith J, Rozengurt E. Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq. Cellular signalling. 2012 April;24(4):914-21. PubMed PMID: 22227248; PubMed Central PMCID: PMC3286641.

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                  Rozengurt E. Protein kinase D signaling: multiple biological functions in health and disease. Physiology (Bethesda, Md.). 2011 February;26(1):23-33. PubMed PMID: 21357900; PubMed Central PMCID: PMC4381749.

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                  Young SH, Rozengurt E. Crosstalk between insulin receptor and G protein-coupled receptor signaling systems leads to Ca²+ oscillations in pancreatic cancer PANC-1 cells. Biochemical and biophysical research communications. 2010 October 8;401(1):154-8. PubMed PMID: 20849815; PubMed Central PMCID: PMC2952715.

                  Harikumar KB, Kunnumakkara AB, Ochi N, Tong Z, Deorukhkar A, Sung B, Kelland L, Jamieson S, Sutherland R, Raynham T, Charles M, Bagherzadeh A, Foxton C, Boakes A, Farooq M, Maru D, Diagaradjane P, Matsuo Y, Sinnett-Smith J, Gelovani J, Krishnan S, Aggarwal BB, Rozengurt E, Ireson CR, Guha S. A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo. Molecular cancer therapeutics. 2010 May;9(5):1136-46. PubMed PMID: 20442301; PubMed Central PMCID: PMC2905628.

                  Kisfalvi K, Hurd C, Guha S, Rozengurt E. Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells. Journal of cellular physiology. 2010 May;223(2):309-16. PubMed PMID: 20082306; PubMed Central PMCID: PMC2888293.

                  Rozengurt E, Sinnett-Smith J, Kisfalvi K. Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2010 May 1;16(9):2505-11. PubMed PMID: 20388847; PubMed Central PMCID: PMC2862089.

                  Weinberg BM, Spiegel BM, Tomlinson JS, Farrell JJ. Asymptomatic pancreatic cystic neoplasms: maximizing survival and quality of life using Markov-based clinical nomograms. Gastroenterology. 2010 February;138(2):531-40. PubMed PMID: 19818780; PubMed Central PMCID: PMC2949077.

                  Torres-Marquez E, Sinnett-Smith J, Guha S, Kui R, Waldron RT, Rey O, Rozengurt E. CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway. Biochemical and biophysical research communications. 2010 January 1;391(1):63-8. PubMed PMID: 19896460; PubMed Central PMCID: PMC2812606.

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                  Jiang X, Sinnett-Smith J, Rozengurt E. Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. Biochemical and biophysical research communications. 2009 September 25;387(3):521-4. PubMed PMID: 19615971; PubMed Central PMCID: PMC2754135.

                  Kisfalvi K, Eibl G, Sinnett-Smith J, Rozengurt E. Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer research. 2009 August 15;69(16):6539-45. PubMed PMID: 19679549; PubMed Central PMCID: PMC2753241.

                  Spiegel BM, Farid M, van Oijen MG, Laine L, Howden CW, Esrailian E. Adherence to best practice guidelines in dyspepsia: a survey comparing dyspepsia experts, community gastroenterologists and primary-care providers. Alimentary pharmacology & therapeutics. 2009 April 15;29(8):871-81. PubMed PMID: 19183152; PubMed Central PMCID: PMC2953468.

                  Desai AA, Bolus R, Nissenson A, Chertow GM, Bolus S, Solomon MD, Khawar OS, Talley J, Spiegel BM. Is there "cherry picking" in the ESRD Program? Perceptions from a Dialysis Provider Survey. Clinical journal of the American Society of Nephrology : CJASN. 2009 April;4(4):772-7. PubMed PMID: 19339407; PubMed Central PMCID: PMC2666440.

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                  McConalogue K, Grady EF, Minnis J, Balestra B, Tonini M, Brecha NC, Bunnett NW, Sternini C. Activation and internalization of the mu-opioid receptor by the newly discovered endogenous agonists, endomorphin-1 and endomorphin-2. Neuroscience. 1999 March;90(3):1051-9. PubMed PMID: 10218804; PubMed Central PMCID: PMC4472477

  Condro MC, Matynia A, Foster NN, Ago Y, Rajbhandari AK, Van C, Jayaram B, Parikh S, Diep AL, Nguyen E, May V, Dong HW, Waschek JA. High-resolution characterization of a PACAP-EGFP transgenic mouse model for mapping PACAP-expressing neurons. The Journal of comparative neurology. 2016 December 15;524(18):3827-3848. PubMed PMID: 27197019; PubMed Central PMCID: PMC5063673.

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                  Hoang-Yen Tran D, Hoang-Ngoc Tran D, Mattai SA, Sallam T, Ortiz C, Lee EC, Robbins L, Ho S, Lee JE, Fisseha E, Shieh C, Sideri A, Shih DQ, Fleshner P, McGovern DP, Vu M, Hing TC, Bakirtzi K, Cheng M, Su B, Law I, Karagiannides I, Targan SR, Gallo RL, Li Z, Koon HW. Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. International journal of obesity (2005). 2016 September;40(9):1424-34. PubMed PMID: 27163748; PubMed Central PMCID: PMC5014693.

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                  Padua D, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih D, Iliopoulos D, Pothoulakis C. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. American journal of physiology. Gastrointestinal and liver physiology. 2016 September 1;311(3):G446-57. PubMed PMID: 27492330; PubMed Central PMCID: PMC5076004.

                  Wang J, Sinnett-Smith J, Stevens JV, Young SH, Rozengurt E. Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD). The Journal of biological chemistry. 2016 August 19;291(34):17988-8005. PubMed PMID: 27369082; PubMed Central PMCID: PMC5016186.

                  Park SH, Videlock EJ, Shih W, Presson AP, Mayer EA, Chang L. Adverse childhood experiences are associated with irritable bowel syndrome and gastrointestinal symptom severity. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 August;28(8):1252-60. PubMed PMID: 27061107; PubMed Central PMCID: PMC4956522.

                  Antonios JP, Soto H, Everson RG, Orpilla J, Moughon D, Shin N, Sedighim S, Yong WH, Li G, Cloughesy TF, Liau LM, Prins RM. PD-1 blockade enhances the vaccination-induced immune response in glioma. JCI insight. 2016 July 7;1(10). PubMed PMID: 27453950; PubMed Central PMCID: PMC4951098.

                  Khalil HA, Lei NY, Brinkley G, Scott A, Wang J, Kar UK, Jabaji ZB, Lewis M, Martín MG, Dunn JC, Stelzner MG. A novel culture system for adult porcine intestinal crypts. Cell and tissue research. 2016 July;365(1):123-34. PubMed PMID: 26928041; PubMed Central PMCID: PMC4919165.

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                  Kaji I, Akiba Y, Konno K, Watanabe M, Kimura S, Iwanaga T, Kuri A, Iwamoto K, Kuwahara A, Kaunitz JD. Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon. The Journal of physiology. 2016 June 15;594(12):3339-52. PubMed PMID: 26854275; PubMed Central PMCID: PMC4908031.

                  Holschneider DP, Guo Y, Mayer EA, Wang Z. Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats. Neurobiology of stress. 2016 June 1;3:8-22. PubMed PMID: 26751119; PubMed Central PMCID: PMC4700548.

                  Padua D, Vu JP, Germano PM, Pisegna JR. The Role of Neuropeptides in Mouse Models of Colitis. Journal of molecular neuroscience : MN. 2016 June;59(2):203-10. PubMed PMID: 26646243; PubMed Central PMCID: PMC4884658.

                  Scott A, Rouch JD, Jabaji Z, Khalil HA, Solorzano S, Lewis M, Martín MG, Stelzner MG, Dunn JC. Long-term renewable human intestinal epithelial stem cells as monolayers: A potential for clinical use. Journal of pediatric surgery. 2016 June;51(6):995-1000. PubMed PMID: 26995514; PubMed Central PMCID: PMC4921284.

                  Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. 2016 June;159(6):1520-1527. PubMed PMID: 26847803; PubMed Central PMCID: PMC4856542.

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                  Yu J, Liu SH, Sanchez R, Nemunaitis J, Rozengurt E, Brunicardi FC. PDX1 associated therapy in translational medicine. Annals of translational medicine. 2016 June;4(11):214. PubMed PMID: 27386488; PubMed Central PMCID: PMC4916355.

                  Bakirtzi K, Law IK, Xue X, Iliopoulos D, Shah YM, Pothoulakis C. Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling. Journal of immunology (Baltimore, Md. : 1950). 2016 May 15;196(10):4311-21. PubMed PMID: 27076683; PubMed Central PMCID: PMC4868643.

                  Deriu E, Boxx GM, He X, Pan C, Benavidez SD, Cen L, Rozengurt N, Shi W, Cheng G. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS pathogens. 2016 May;12(5):e1005572. PubMed PMID: 27149619; PubMed Central PMCID: PMC4858270.

                  Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Molecular cancer research : MCR. 2016 May;14(5):437-47. PubMed PMID: 26979711; PubMed Central PMCID: PMC4867256.

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                  Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Science translational medicine. 2016 April 13;8(334):334ra54. PubMed PMID: 27075628; PubMed Central PMCID: PMC4934679.

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                  Gupta A, Labus J, Kilpatrick LA, Bonyadi M, Ashe-McNalley C, Heendeniya N, Bradesi S, Chang L, Mayer EA. Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females. Brain structure & function. 2016 April;221(3):1667-79. PubMed PMID: 25630611; PubMed Central PMCID: PMC4573367.

                  Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly. International journal of antimicrobial agents. 2016 April;47(4):289-96. PubMed PMID: 27013001; PubMed Central PMCID: PMC4833571.

                  Wang J, Han L, Sinnett-Smith J, Han LL, Stevens JV, Rozengurt N, Young SH, Rozengurt E. Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552. American journal of physiology. Cell physiology. 2016 April 1;310(7):C542-57. PubMed PMID: 26739494; PubMed Central PMCID: PMC4824155.

                  Yuan PQ, Wu SV, Pothoulakis C, Taché Y. Urocortins and CRF receptor type 2 variants in the male rat colon: gene expression and regulation by endotoxin and anti-inflammatory effect. American journal of physiology. Gastrointestinal and liver physiology. 2016 March 15;310(6):G387-98. PubMed PMID: 26744472; PubMed Central PMCID: PMC4796293.

                  Hertzer KM, Xu M, Moro A, Dawson DW, Du L, Li G, Chang HH, Stark AP, Jung X, Hines OJ, Eibl G. Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer. Pancreas. 2016 March;45(3):458-65. PubMed PMID: 26495779; PubMed Central PMCID: PMC4854638.

                  Mahurkar S, Polytarchou C, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 March;28(3):410-22. PubMed PMID: 26670691; PubMed Central PMCID: PMC4760882.

                  Law IK, Jensen D, Bunnett NW, Pothoulakis C. Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin. Scientific reports. 2016 February 23;6:22195. PubMed PMID: 26902265; PubMed Central PMCID: PMC4763298.

                  Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi K, Dulai GS, Machicado GA. Natural history of definitive diverticular hemorrhage based on stigmata of recent hemorrhage and colonoscopic Doppler blood flow monitoring for risk stratification and definitive hemostasis. Gastrointestinal endoscopy. 2016 February;83(2):416-23. PubMed PMID: 26227931; PubMed Central PMCID: PMC4715947.

                  Walwyn WM, Chen W, Kim H, Minasyan A, Ennes HS, McRoberts JA, Marvizón JC. Sustained Suppression of Hyperalgesia during Latent Sensitization by μ-, δ-, and κ-opioid receptors and α2A Adrenergic Receptors: Role of Constitutive Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2016 January 6;36(1):204-21. PubMed PMID: 26740662; PubMed Central PMCID: PMC4701961.

                  Birtolo C, Go VL, Ptasznik A, Eibl G, Pandol SJ. Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas. 2016 January;45(1):21-31. PubMed PMID: 26658038; PubMed Central PMCID: PMC4859755.

                  Camus M, Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi KA, Machicado GA, Dulai GS, Jensen ME, Gornbein JA. Comparison of Three Risk Scores to Predict Outcomes of Severe Lower Gastrointestinal Bleeding. Journal of clinical gastroenterology. 2016 January;50(1):52-8. PubMed PMID: 25599218; PubMed Central PMCID: PMC4504830.

                  Hoffman JM, Baritaki S, Ruiz JJ, Sideri A, Pothoulakis C. Corticotropin-Releasing Hormone Receptor 2 Signaling Promotes Mucosal Repair Responses after Colitis. The American journal of pathology. 2016 January;186(1):134-44. PubMed PMID: 26597886; PubMed Central PMCID: PMC4714033.

                  Hong JY, Naliboff B, Labus JS, Gupta A, Kilpatrick LA, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Mayer EA. Altered brain responses in subjects with irritable bowel syndrome during cued and uncued pain expectation. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 January;28(1):127-38. PubMed PMID: 26526698; PubMed Central PMCID: PMC4943658.

                  Jarcho JM, Feier NA, Labus JS, Naliboff B, Smith SR, Hong JY, Colloca L, Tillisch K, Mandelkern MA, Mayer EA, London ED. Placebo analgesia: Self-report measures and preliminary evidence of cortical dopamine release associated with placebo response. NeuroImage. Clinical. 2016;10:107-14. PubMed PMID: 26759785; PubMed Central PMCID: PMC4683423.

                  Jensen DM, Ohning GV, Kovacs TO, Ghassemi KA, Jutabha R, Dulai GS, Machicado GA. Doppler endoscopic probe as a guide to risk stratification and definitive hemostasis of peptic ulcer bleeding. Gastrointestinal endoscopy. 2016 January;83(1):129-36. PubMed PMID: 26318834; PubMed Central PMCID: PMC4691549.

                  Labus JS, Naliboff B, Kilpatrick L, Liu C, Ashe-McNalley C, dos Santos IR, Alaverdyan M, Woodworth D, Gupta A, Ellingson BM, Tillisch K, Mayer EA. Pain and Interoception Imaging Network (PAIN): A multimodal, multisite, brain-imaging repository for chronic somatic and visceral pain disorders. NeuroImage. 2016 January 1;124(Pt B):1232-7. PubMed PMID: 25902408; PubMed Central PMCID: PMC4627849.

                  Latorre R, Huynh J, Mazzoni M, Gupta A, Bonora E, Clavenzani P, Chang L, Mayer EA, De Giorgio R, Sternini C. Expression of the Bitter Taste Receptor, T2R38, in Enteroendocrine Cells of the Colonic Mucosa of Overweight/Obese vs. Lean Subjects. PloS one. 2016;11(2):e0147468. PubMed PMID: 26866366; PubMed Central PMCID: PMC4750998.

                  Moussaoui N, Larauche M, Biraud M, Molet J, Million M, Mayer E, Taché Y. Limited Nesting Stress Alters Maternal Behavior and In Vivo Intestinal Permeability in Male Wistar Pup Rats. PloS one. 2016;11(5):e0155037. PubMed PMID: 27149676; PubMed Central PMCID: PMC4858303.

                  Rouch JD, Scott A, Lei NY, Solorzano-Vargas RS, Wang J, Hanson EM, Kobayashi M, Lewis M, Stelzner MG, Dunn JC, Eckmann L, Martín MG. Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. PloS one. 2016;11(1):e0148216. PubMed PMID: 26820624; PubMed Central PMCID: PMC4731053.

                  Zhou G, Yu J, Wang A, Liu SH, Sinnett-Smith J, Wu J, Sanchez R, Nemunaitis J, Ricordi C, Rozengurt E, Brunicardi FC. Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma. Current molecular medicine. 2016;16(1):83-90. PubMed PMID: 26695692; PubMed Central PMCID: PMC4994969.

                  Vuong HE, Hardi CN, Barnes S, Brecha NC. Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 December 2;35(48):15955-70. PubMed PMID: 26631476; PubMed Central PMCID: PMC4666919.

                  Kilpatrick LA, Istrin JJ, Gupta A, Naliboff BD, Tillisch K, Labus JS, Mayer EA. Sex commonalities and differences in the relationship between resilient personality and the intrinsic connectivity of the salience and default mode networks. Biological psychology. 2015 December;112:107-15. PubMed PMID: 26440126; PubMed Central PMCID: PMC5012423.

                  Phan J, Benhammou JN, Pisegna JR. Gastric Hypersecretory States: Investigation and Management. Current treatment options in gastroenterology. 2015 December;13(4):386-97. PubMed PMID: 26342486; PubMed Central PMCID: PMC4633316.

                  Stark AP, Chang HH, Jung X, Moro A, Hertzer K, Xu M, Schmidt A, Hines OJ, Eibl G. E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice. Surgery. 2015 December;158(6):1564-72. PubMed PMID: 26297056; PubMed Central PMCID: PMC4637247.

                  Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of experimental medicine. 2015 November 16;212(12):2147-63. PubMed PMID: 26552708; PubMed Central PMCID: PMC4647265.

                  Chang HH, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G. Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1. American journal of physiology. Cell physiology. 2015 November 15;309(10):C639-49. PubMed PMID: 26310818; PubMed Central PMCID: PMC4652080.

                  Vu JP, Goyal D, Luong L, Oh S, Sandhu R, Norris J, Parsons W, Pisegna JR, Germano PM. PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin. American journal of physiology. Gastrointestinal and liver physiology. 2015 November 15;309(10):G816-25. PubMed PMID: 26336928; PubMed Central PMCID: PMC4652141.

                  Young SH, Rey O, Rozengurt E. Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: Impact of the highly conservative mutation Ser170Thr. Biochemical and biophysical research communications. 2015 November 6;467(1):1-6. PubMed PMID: 26431875; PubMed Central PMCID: PMC4613767.

                  Rodriguez JA, Huerta-Yepez S, Law IK, Baay-Guzman GJ, Tirado-Rodriguez B, Hoffman JM, Iliopoulos D, Hommes DW, Verspaget HW, Chang L, Pothoulakis C, Baritaki S. Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling. Cellular and molecular gastroenterology and hepatology. 2015 November 1;1(6):610-630. PubMed PMID: 26495412; PubMed Central PMCID: PMC4610032.

                  Vuong HE, Pérez de Sevilla Müller L, Hardi CN, McMahon DG, Brecha NC. Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines. Neuroscience. 2015 October 29;307:319-37. PubMed PMID: 26335381; PubMed Central PMCID: PMC4603663.

                  Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D. MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice. Gastroenterology. 2015 October;149(4):981-92.e11. PubMed PMID: 26055138; PubMed Central PMCID: PMC4584179.

                  Fang K, Sideri A, Law IK, Bakirtzi K, Polytarchou C, Iliopoulos D, Pothoulakis C. Identification of a novel substance P (SP)-neurokinin-1 receptor (NK-1R) microRNA-221-5p inflammatory network in human colonic epithelial cells. Cellular and molecular gastroenterology and hepatology. 2015 September 1;1(5):503-515. PubMed PMID: 26645045; PubMed Central PMCID: PMC4669978.

                  Hubbard CS, Hong J, Jiang Z, Ebrat B, Suyenobu B, Smith S, Heendeniya N, Naliboff BD, Tillisch K, Mayer EA, Labus JS. Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 September;27(9):1282-94. PubMed PMID: 26087779; PubMed Central PMCID: PMC4550526.

                  Cherukuri DP, Deignan JL, Das K, Grody WW, Herschman H. Instability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma. Molecular oncology. 2015 August;9(7):1252-8. PubMed PMID: 25817443; PubMed Central PMCID: PMC4523444.

                  Irimia A, Labus JS, Torgerson CM, Van Horn JD, Mayer EA. Altered viscerotopic cortical innervation in patients with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 August;27(8):1075-81. PubMed PMID: 25952540; PubMed Central PMCID: PMC4520752.

                  Kaunitz JD. The Discovery of PCR: ProCuRement of Divine Power. Digestive diseases and sciences. 2015 August;60(8):2230-1. PubMed PMID: 26077976; PubMed Central PMCID: PMC4501591.

                  Kobayashi M, Lei NY, Wang Q, Wu BM, Dunn JC. Orthogonally oriented scaffolds with aligned fibers for engineering intestinal smooth muscle. Biomaterials. 2015 August;61:75-84. PubMed PMID: 26001072; PubMed Central PMCID: PMC4464968.

                  Labus JS, Van Horn JD, Gupta A, Alaverdyan M, Torgerson C, Ashe-McNalley C, Irimia A, Hong JY, Naliboff B, Tillisch K, Mayer EA. Multivariate morphological brain signatures predict patients with chronic abdominal pain from healthy control subjects. Pain. 2015 August;156(8):1545-54. PubMed PMID: 25906347; PubMed Central PMCID: PMC4504800.

                  O'Mahony F, Wroblewski K, O'Byrne SM, Jiang H, Clerkin K, Benhammou J, Blaner WS, Beaven SW. Liver X receptors balance lipid stores in hepatic stellate cells through Rab18, a retinoid responsive lipid droplet protein. Hepatology (Baltimore, Md.). 2015 August;62(2):615-26. PubMed PMID: 25482505; PubMed Central PMCID: PMC4458237.

                  Tuominen I, Beaven SW. Intestinal farnesoid X receptor puts a fresh coat of wax on fatty liver. Hepatology (Baltimore, Md.). 2015 August;62(2):646-8. PubMed PMID: 25998695; PubMed Central PMCID: PMC4523235.

                  Law IK, Bakirtzi K, Polytarchou C, Oikonomopoulos A, Hommes D, Iliopoulos D, Pothoulakis C. Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis. Gut. 2015 July;64(7):1095-104. PubMed PMID: 25112884; PubMed Central PMCID: PMC4422787.

                  Lugea A, Waldron RT, Pandol SJ. Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2015 July;15(4 Suppl):S1-5. PubMed PMID: 25736240; PubMed Central PMCID: PMC4515411.

                  Stengel A, Karasawa H, Taché Y. The role of brain somatostatin receptor 2 in the regulation of feeding and drinking behavior. Hormones and behavior. 2015 July;73:15-22. PubMed PMID: 26026616; PubMed Central PMCID: PMC4546908.

                  Sanmiguel C, Gupta A, Mayer EA. Gut Microbiome and Obesity: A Plausible Explanation for Obesity. Current obesity reports. 2015 June;4(2):250-61. PubMed PMID: 26029487; PubMed Central PMCID: PMC4443745.

                  Vu JP, Larauche M, Flores M, Luong L, Norris J, Oh S, Liang LJ, Waschek J, Pisegna JR, Germano PM. Regulation of Appetite, Body Composition, and Metabolic Hormones by Vasoactive Intestinal Polypeptide (VIP). Journal of molecular neuroscience : MN. 2015 June;56(2):377-87. PubMed PMID: 25904310; PubMed Central PMCID: PMC4458420.

                  Gupta A, Rapkin AJ, Gill Z, Kilpatrick L, Fling C, Stains J, Masghati S, Tillisch K, Mayer EA, Labus JS. Disease-related differences in resting-state networks: a comparison between localized provoked vulvodynia, irritable bowel syndrome, and healthy control subjects. Pain. 2015 May;156(5):809-19. PubMed PMID: 25735001; PubMed Central PMCID: PMC4402252.

                  Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D. A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. Inflammatory bowel diseases. 2015 May;21(5):996-1005. PubMed PMID: 25738378; PubMed Central PMCID: PMC4402238.

                  Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JC, Martin MG, Lagasse E, Zhang L, Yu J. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Scientific reports. 2015 April 10;5:8566. PubMed PMID: 25858503; PubMed Central PMCID: PMC4392360.

                  Wu JX, Liu SH, Nemunaitis JJ, Brunicardi FC. Liposomal insulin promoter-thymidine kinase gene therapy followed by ganciclovir effectively ablates human pancreatic cancer in mice. Cancer letters. 2015 April 10;359(2):206-10. PubMed PMID: 25596375; PubMed Central PMCID: PMC4336837.

                  Akiba Y, Kaunitz JD, Million M. Peripheral corticotropin-releasing factor receptor type 2 activation increases colonic blood flow through nitric oxide pathway in rats. Digestive diseases and sciences. 2015 April;60(4):858-67. PubMed PMID: 25701320; PubMed Central PMCID: PMC4501405.

                  Anselmi L, Huynh J, Duraffourd C, Jaramillo I, Vegezzi G, Saccani F, Boschetti E, Brecha NC, De Giorgio R, Sternini C. Activation of μ opioid receptors modulates inflammation in acute experimental colitis. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 April;27(4):509-23. PubMed PMID: 25690069; PubMed Central PMCID: PMC4405133.

                  Liu Z, Sun F, Braun J, McGovern DP, Piantadosi S. Multilevel regularized regression for simultaneous taxa selection and network construction with metagenomic count data. Bioinformatics (Oxford, England). 2015 April 1;31(7):1067-74. PubMed PMID: 25416747; PubMed Central PMCID: PMC4382903.

                  Marvizon JC, Walwyn W, Minasyan A, Chen W, Taylor BK. Latent sensitization: a model for stress-sensitive chronic pain. Current protocols in neuroscience. 2015 April 1;71:9.50.1-14. PubMed PMID: 25829356; PubMed Central PMCID: PMC4532319.

                  Mayer EA, Gupta A, Kilpatrick LA, Hong JY. Imaging brain mechanisms in chronic visceral pain. Pain. 2015 April;156 Suppl 1:S50-63. PubMed PMID: 25789437; PubMed Central PMCID: PMC4428597.

                  Sideri A, Stavrakis D, Bowe C, Shih DQ, Fleshner P, Arsenescu V, Arsenescu R, Turner JR, Pothoulakis C, Karagiannides I. Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1. American journal of physiology. Gastrointestinal and liver physiology. 2015 April 1;308(7):G591-604. PubMed PMID: 25591865; PubMed Central PMCID: PMC4385897.

                  Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2. Molecular cancer therapeutics. 2015 April;14(4):1014-23. PubMed PMID: 25673820; PubMed Central PMCID: PMC4394038.

                  Tarling EJ, Ahn H, de Aguiar Vallim TQ. The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2. Arteriosclerosis, thrombosis, and vascular biology. 2015 April;35(4):787-95. PubMed PMID: 25593129; PubMed Central PMCID: PMC4376635.

                  Gukovsky I, Gukovskaya AS. Impaired autophagy triggers chronic pancreatitis: lessons from pancreas-specific atg5 knockout mice. Gastroenterology. 2015 March;148(3):501-5. PubMed PMID: 25613315; PubMed Central PMCID: PMC4443443.

                  Liu Y, Ji H, Zhang Y, Shen X, Gao F, He X, Li GA, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury. Journal of hepatology. 2015 March;62(3):563-72. PubMed PMID: 25450716; PubMed Central PMCID: PMC4336640.

                  Sakanaka T, Inoue T, Yorifuji N, Iguchi M, Fujiwara K, Narabayashi K, Kakimoto K, Nouda S, Okada T, Kuramoto T, Ishida K, Abe Y, Takeuchi T, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. The effects of a TGR5 agonist and a dipeptidyl peptidase IV inhibitor on dextran sulfate sodium-induced colitis in mice. Journal of gastroenterology and hepatology. 2015 March;30 Suppl 1:60-5. PubMed PMID: 25827806; PubMed Central PMCID: PMC4874188.

                  Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. The Journal of biological chemistry. 2015 February 27;290(9):5566-81. PubMed PMID: 25468909; PubMed Central PMCID: PMC4342471.

                  Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. Septin dynamics are essential for exocytosis. The Journal of biological chemistry. 2015 February 27;290(9):5280-97. PubMed PMID: 25575596; PubMed Central PMCID: PMC4342448.

                  Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell metabolism. 2015 February 3;21(2):334-46. PubMed PMID: 25651185; PubMed Central PMCID: PMC4349439.

                  de Aguiar Vallim TQ, Tarling EJ, Ahn H, Hagey LR, Romanoski CE, Lee RG, Graham MJ, Motohashi H, Yamamoto M, Edwards PA. MAFG is a transcriptional repressor of bile acid synthesis and metabolism. Cell metabolism. 2015 February 3;21(2):298-310. PubMed PMID: 25651182; PubMed Central PMCID: PMC4317590.

                  Bromley EG, May FP, Federer L, Spiegel BM, van Oijen MG. Explaining persistent under-use of colonoscopic cancer screening in African Americans: a systematic review. Preventive medicine. 2015 February;71:40-8. PubMed PMID: 25481094; PubMed Central PMCID: PMC4329030.

                  Kaji I, Iwanaga T, Watanabe M, Guth PH, Engel E, Kaunitz JD, Akiba Y. SCFA transport in rat duodenum. American journal of physiology. Gastrointestinal and liver physiology. 2015 February 1;308(3):G188-97. PubMed PMID: 25394661; PubMed Central PMCID: PMC4312951.

                  Nguyen AH, Toste PA, Farrell JJ, Clerkin BM, Williams J, Muthusamy VR, Watson RR, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Current recommendations for surveillance and surgery of intraductal papillary mucinous neoplasms may overlook some patients with cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2015 February;19(2):258-65. PubMed PMID: 25373706; PubMed Central PMCID: PMC4305480.

                  Tan YV, Abad C, Wang Y, Lopez R, Waschek J. VPAC2 (vasoactive intestinal peptide receptor type 2) receptor deficient mice develop exacerbated experimental autoimmune encephalomyelitis with increased Th1/Th17 and reduced Th2/Treg responses. Brain, behavior, and immunity. 2015 February;44:167-175. PubMed PMID: 25305591; PubMed Central PMCID: PMC4275378.

                  Taché Y, Million M. Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia. Journal of neurogastroenterology and motility. 2015 January 31;21(1):8-24. PubMed PMID: 25611064; PubMed Central PMCID: PMC4288101.

                  Coveleskie K, Gupta A, Kilpatrick LA, Mayer ED, Ashe-McNalley C, Stains J, Labus JS, Mayer EA. Altered functional connectivity within the central reward network in overweight and obese women. Nutrition & diabetes. 2015 January 19;5:e148. PubMed PMID: 25599560; PubMed Central PMCID: PMC4314578.

                  Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology. 2015 January 15;475:46-55. PubMed PMID: 25462345; PubMed Central PMCID: PMC4284078.

                  Abad C, Cheung-Lau G, Coûté-Monvoisin AC, Waschek JA. Vasoactive intestinal peptide-deficient mice exhibit reduced pathology in trinitrobenzene sulfonic acid-induced colitis. Neuroimmunomodulation. 2015;22(3):203-12. PubMed PMID: 25301381; PubMed Central PMCID: PMC4297532.

                  Bradesi S, Karagiannides I, Bakirtzi K, Joshi SM, Koukos G, Iliopoulos D, Pothoulakis C, Mayer EA. Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat. PloS one. 2015;10(7):e0130938. PubMed PMID: 26222740; PubMed Central PMCID: PMC4519289.

                  Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. Journal of Alzheimer's disease : JAD. 2015;43(3):967-76. PubMed PMID: 25125464; PubMed Central PMCID: PMC4258165.

                  Chen R, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM, Maitra A, Brentnall TA. Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. Laboratory investigation; a journal of technical methods and pathology. 2015 January;95(1):43-55. PubMed PMID: 25347153; PubMed Central PMCID: PMC4281293.

                  Cheng M, Ho S, Yoo JH, Tran DH, Bakirtzi K, Su B, Tran DH, Kubota Y, Ichikawa R, Koon HW. Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts. Clinical and experimental gastroenterology. 2015;8:13-29. PubMed PMID: 25565877; PubMed Central PMCID: PMC4274046.

                  Gupta A, Mayer EA, Sanmiguel CP, Van Horn JD, Woodworth D, Ellingson BM, Fling C, Love A, Tillisch K, Labus JS. Patterns of brain structural connectivity differentiate normal weight from overweight subjects. NeuroImage. Clinical. 2015;7:506-17. PubMed PMID: 25737959; PubMed Central PMCID: PMC4338207.

                  Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 January 1;21(1):157-65. PubMed PMID: 25348515; PubMed Central PMCID: PMC4286535.

                  Khalil HA, Lei NY, Nie W, Lewis MS, Stelzner MG, Martín MG, Dunn JC, Yoo J. Primary Myofibroblasts Maintain Short-Term Viability following Submucosal Injection in Syngeneic, Immune-Competent Mice Utilizing Murine Colonoscopy. PloS one. 2015;10(5):e0127258. PubMed PMID: 26016485; PubMed Central PMCID: PMC4445916.

                  Kutch JJ, Yani MS, Asavasopon S, Kirages DJ, Rana M, Cosand L, Labus JS, Kilpatrick LA, Ashe-McNalley C, Farmer MA, Johnson KA, Ness TJ, Deutsch G, Harris RE, Apkarian AV, Clauw DJ, Mackey SC, Mullins C, Mayer EA. Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study. NeuroImage. Clinical. 2015;8:493-502. PubMed PMID: 26106574; PubMed Central PMCID: PMC4474411.

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                  Li Y, Go VL, Sarkar FH. The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome. Pancreas. 2015 January;44(1):1-10. PubMed PMID: 25493373; PubMed Central PMCID: PMC4264839.

                  Martinez L, Ermolova NV, Ishikawa TO, Stout DB, Herschman HR, Spencer MJ. A reporter mouse for optical imaging of inflammation in mdx muscles. Skeletal muscle. 2015;5:15. PubMed PMID: 25949789; PubMed Central PMCID: PMC4422315.

                  Marzagalli R, Scuderi S, Drago F, Waschek JA, Castorina A. Emerging Role of PACAP as a New Potential Therapeutic Target in Major Diabetes Complications. International journal of endocrinology. 2015;2015:160928. PubMed PMID: 26074958; PubMed Central PMCID: PMC4446501.

                  McGowan I, Anton PA, Elliott J, Cranston RD, Duffill K, Althouse AD, Hawkins KL, De Rosa SC. Exploring the feasibility of multi-site flow cytometric processing of gut associated lymphoid tissue with centralized data analysis for multi-site clinical trials. PloS one. 2015;10(5):e0126454. PubMed PMID: 26010577; PubMed Central PMCID: PMC4444258.

                  Mulak A, Larauche M, Biraud M, Million M, Rivier J, Taché Y. Selective agonists of somatostatin receptor subtype 1 or 2 injected peripherally induce antihyperalgesic effect in two models of visceral hypersensitivity in mice. Peptides. 2015 January;63:71-80. PubMed PMID: 25451334; PubMed Central PMCID: PMC4385413.

                  Orand A, Gupta A, Shih W, Presson AP, Hammer C, Niesler B, Heendeniya N, Mayer EA, Chang L. Catecholaminergic Gene Polymorphisms Are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome. PloS one. 2015;10(8):e0135910. PubMed PMID: 26288143; PubMed Central PMCID: PMC4546052.

                  Taché Y. Corticotrophin-releasing factor 1 activation in the central amygdale and visceral hyperalgesia. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 January;27(1):1-6. PubMed PMID: 25557223; PubMed Central PMCID: PMC4389773.

                  Wang L, Mogami S, Yakabi S, Karasawa H, Yamada C, Yakabi K, Hattori T, Taché Y. Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito. PloS one. 2015;10(9):e0139325. PubMed PMID: 26421719; PubMed Central PMCID: PMC4589401.

                  Wang Y, Yan C, Liu L, Wang W, Du H, Fan W, Lutfy K, Jiang M, Friedman TC, Liu Y. 11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue. American journal of physiology. Endocrinology and metabolism. 2015 January 1;308(1):E84-95. PubMed PMID: 25389364; PubMed Central PMCID: PMC4281684.

                  Yoo JH, Ho S, Tran DH, Cheng M, Bakirtzi K, Kukota Y, Ichikawa R, Su B, Tran DH, Hing TC, Chang I, Shih DQ, Issacson RE, Gallo RL, Fiocchi C, Pothoulakis C, Koon HW. Anti-fibrogenic effects of the anti-microbial peptide cathelicidin in murine colitis-associated fibrosis. Cellular and molecular gastroenterology and hepatology. 2015 January;1(1):55-74.e1. PubMed PMID: 25729764; PubMed Central PMCID: PMC4338438.

                  Zhu J, Lu T, Yue S, Shen X, Gao F, Busuttil RW, Kupiec-Weglinski JW, Xia Q, Zhai Y. Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation. Transplantation. 2015 January;99(1):48-55. PubMed PMID: 25340604; PubMed Central PMCID: PMC4272660.

                  Akiba Y, Kaunitz JD. Prostaglandin pathways in duodenal chemosensing. Journal of gastroenterology and hepatology. 2014 December;29 Suppl 4:93-8. PubMed PMID: 25521740; PubMed Central PMCID: PMC4451058.

                  Bagarinao E, Johnson KA, Martucci KT, Ichesco E, Farmer MA, Labus J, Ness TJ, Harris R, Deutsch G, Apkarian AV, Mayer EA, Clauw DJ, Mackey S. Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network study. Pain. 2014 December;155(12):2502-9. PubMed PMID: 25242566; PubMed Central PMCID: PMC4504202.

                  Buzzanco A, Gomez A, Rodriguez E, French BA, Tillman BA, Chang S, Ganapathy E, Junrungsee S, Zarrinpar A, Agopian VG, Naini BV, French SW Jr, French SW Sr. Digital quantitation of HCC-associated stem cell markers and protein quality control factors using tissue arrays of human liver sections. Experimental and molecular pathology. 2014 December;97(3):399-410. PubMed PMID: 25218810; PubMed Central PMCID: PMC4262606.

                  Donahue TR, Nguyen AH, Moughan J, Li L, Tatishchev S, Toste P, Farrell JJ. Stromal microRNA-21 levels predict response to 5-fluorouracil in patients with pancreatic cancer. Journal of surgical oncology. 2014 December;110(8):952-9. PubMed PMID: 25132574; PubMed Central PMCID: PMC4232442.

                  Ji H, Liu Y, Zhang Y, Shen XD, Gao F, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. T-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury. Hepatology (Baltimore, Md.). 2014 December;60(6):2052-2064. PubMed PMID: 25066922; PubMed Central PMCID: PMC4396987.

                  Karasawa H, Pietra C, Giuliano C, Garcia-Rubio S, Xu X, Yakabi S, Taché Y, Wang L. New ghrelin agonist, HM01 alleviates constipation and L-dopa-delayed gastric emptying in 6-hydroxydopamine rat model of Parkinson's disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 December;26(12):1771-82. PubMed PMID: 25327342; PubMed Central PMCID: PMC4457321.

                  Stengel A, Taché Y. Brain peptides and the modulation of postoperative gastric ileus. Current opinion in pharmacology. 2014 December;19:31-7. PubMed PMID: 24999843; PubMed Central PMCID: PMC4254047.

                  Wagner JP, Sullins VF, Dunn JC. Skin-derived precursors generate enteric-type neurons in aganglionic jejunum. Journal of pediatric surgery. 2014 December;49(12):1809-14. PubMed PMID: 25487489; PubMed Central PMCID: PMC4261145.

                  Wagner JP, Sullins VF, Khalil HA, Dunn JC. A durable model of Hirschsprung's colon. Journal of pediatric surgery. 2014 December;49(12):1804-8. PubMed PMID: 25487488; PubMed Central PMCID: PMC4261142.

                  Hong C, Marshall SM, McDaniel AL, Graham M, Layne JD, Cai L, Scotti E, Boyadjian R, Kim J, Chamberlain BT, Tangirala RK, Jung ME, Fong L, Lee R, Young SG, Temel RE, Tontonoz P. The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice. Cell metabolism. 2014 November 4;20(5):910-8. PubMed PMID: 25440061; PubMed Central PMCID: PMC4261644.

                  Tong M, Jacobs JP, McHardy IH, Braun J. Sampling of intestinal microbiota and targeted amplification of bacterial 16S rRNA genes for microbial ecologic analysis. Current protocols in immunology. 2014 November 3;107:7.41.1-11. PubMed PMID: 25367129; PubMed Central PMCID: PMC4457454.

                  Balaji K, French CT, Miller JF, Colicelli J. The RAB5-GEF function of RIN1 regulates multiple steps during Listeria monocytogenes infection. Traffic (Copenhagen, Denmark). 2014 November;15(11):1206-18. PubMed PMID: 25082076; PubMed Central PMCID: PMC4282165.

                  Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR. Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. Molecular cancer research : MCR. 2014 November;12(11):1677-88. PubMed PMID: 25063587; PubMed Central PMCID: PMC4233191.

                  Rozengurt E, Soares HP, Sinnet-Smith J. Suppression of feedback loops mediated by PI3K/mTOR induces multiple overactivation of compensatory pathways: an unintended consequence leading to drug resistance. Molecular cancer therapeutics. 2014 November;13(11):2477-88. PubMed PMID: 25323681; PubMed Central PMCID: PMC4222988.

                  Shih DQ, Zheng L, Zhang X, Zhang H, Kanazawa Y, Ichikawa R, Wallace KL, Chen J, Pothoulakis C, Koon HW, Targan SR. Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis. Mucosal immunology. 2014 November;7(6):1492-503. PubMed PMID: 24850426; PubMed Central PMCID: PMC4205266.

                  Spiegel BM, Hays RD, Bolus R, Melmed GY, Chang L, Whitman C, Khanna PP, Paz SH, Hays T, Reise S, Khanna D. Development of the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) gastrointestinal symptom scales. The American journal of gastroenterology. 2014 November;109(11):1804-14. PubMed PMID: 25199473; PubMed Central PMCID: PMC4285435.

                  Hong JY, Kilpatrick LA, Labus JS, Gupta A, Katibian D, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Naliboff B, Mayer EA. Sex and disease-related alterations of anterior insula functional connectivity in chronic abdominal pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 October 22;34(43):14252-9. PubMed PMID: 25339739; PubMed Central PMCID: PMC4205551.

                  Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Molecular cancer therapeutics. 2014 October;13(10):2303-14. PubMed PMID: 25082960; PubMed Central PMCID: PMC4188417.

                  Itoh Y, Arnold AP. X chromosome regulation of autosomal gene expression in bovine blastocysts. Chromosoma. 2014 October;123(5):481-9. PubMed PMID: 24817096; PubMed Central PMCID: PMC4170013.

                  Ruegger PM, Clark RT, Weger JR, Braun J, Borneman J. Improved resolution of bacteria by high throughput sequence analysis of the rRNA internal transcribed spacer. Journal of microbiological methods. 2014 October;105:82-7. PubMed PMID: 25034229; PubMed Central PMCID: PMC4160368.

                  Arnold AP. Conceptual frameworks and mouse models for studying sex differences in physiology and disease: why compensation changes the game. Experimental neurology. 2014 September;259:2-9. PubMed PMID: 24509348; PubMed Central PMCID: PMC4125548.

                  Im E, Jung J, Pothoulakis C, Rhee SH. Disruption of Pten speeds onset and increases severity of spontaneous colitis in Il10(-/-) mice. Gastroenterology. 2014 September;147(3):667-679.e10. PubMed PMID: 24882466; PubMed Central PMCID: PMC4143453.

                  Liu Y, Yuan J, Tan T, Jia W, Lugea A, Mareninova O, Waldron RT, Pandol SJ. Genetic inhibition of protein kinase Cε attenuates necrosis in experimental pancreatitis. American journal of physiology. Gastrointestinal and liver physiology. 2014 September 1;307(5):G550-63. PubMed PMID: 25035113; PubMed Central PMCID: PMC4154116.

                  Costes S, Butler PC. Insulin-degrading enzyme inhibition, a novel therapy for type 2 diabetes?. Cell metabolism. 2014 August 5;20(2):201-3. PubMed PMID: 25100059; PubMed Central PMCID: PMC4144405.

                  Calkin AC, Lee SD, Kim J, Van Stijn CM, Wu XH, Lusis AJ, Hong C, Tangirala RI, Tontonoz P. Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in mice. Circulation research. 2014 August 1;115(4):442-9. PubMed PMID: 24935961; PubMed Central PMCID: PMC4119488.

                  Koon HW, Ho S, Hing TC, Cheng M, Chen X, Ichikawa Y, Kelly CP, Pothoulakis C. Fidaxomicin inhibits Clostridium difficile toxin A-mediated enteritis in the mouse ileum. Antimicrobial agents and chemotherapy. 2014 August;58(8):4642-50. PubMed PMID: 24890583; PubMed Central PMCID: PMC4135997.

                  Ngun TC, Ghahramani NM, Creek MM, Williams-Burris SM, Barseghyan H, Itoh Y, Sánchez FJ, McClusky R, Sinsheimer JS, Arnold AP, Vilain E. Feminized behavior and brain gene expression in a novel mouse model of Klinefelter Syndrome. Archives of sexual behavior. 2014 August;43(6):1043-57. PubMed PMID: 24923877; PubMed Central PMCID: PMC4371776.

                  Viitasalo L, Niemi L, Ashorn M, Ashorn S, Braun J, Huhtala H, Collin P, Mäki M, Kaukinen K, Kurppa K, Iltanen S. Early microbial markers of celiac disease. Journal of clinical gastroenterology. 2014 August;48(7):620-4. PubMed PMID: 24518796; PubMed Central PMCID: PMC4082475.

                  Karasawa H, Yakabi S, Wang L, Taché Y. Orexin-1 receptor mediates the increased food and water intake induced by intracerebroventricular injection of the stable somatostatin pan-agonist, ODT8-SST in rats. Neuroscience letters. 2014 July 25;576:88-92. PubMed PMID: 24915296; PubMed Central PMCID: PMC4096604.

                  Lin L, Ma C, Wei B, Aziz N, Rajalingam R, Yusung S, Erlich HA, Trachtenberg EA, Targan SR, McGovern DP, Heath JR, Braun J. Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function. Journal of immunology (Baltimore, Md. : 1950). 2014 July 15;193(2):940-9. PubMed PMID: 24935928; PubMed Central PMCID: PMC4096688.

                  Gupta A, Kilpatrick L, Labus J, Tillisch K, Braun A, Hong JY, Ashe-McNalley C, Naliboff B, Mayer EA. Early adverse life events and resting state neural networks in patients with chronic abdominal pain: evidence for sex differences. Psychosomatic medicine. 2014 July;76(6):404-12. PubMed PMID: 25003944; PubMed Central PMCID: PMC4113723.

                  Inoue T, Higashiyama M, Kaji I, Rudenkyy S, Higuchi K, Guth PH, Engel E, Kaunitz JD, Akiba Y. Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats. Digestive diseases and sciences. 2014 June;59(6):1286-95. PubMed PMID: 24379150; PubMed Central PMCID: PMC4196264.

                  Sallam T, Ito A, Rong X, Kim J, van Stijn C, Chamberlain BT, Jung ME, Chao LC, Jones M, Gilliland T, Wu X, Su GL, Tangirala RK, Tontonoz P, Hong C. The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis. Journal of lipid research. 2014 June;55(6):1120-30. PubMed PMID: 24671012; PubMed Central PMCID: PMC4031943.

                  Chen W, McRoberts JA, Marvizón JC. μ-Opioid receptor inhibition of substance P release from primary afferents disappears in neuropathic pain but not inflammatory pain. Neuroscience. 2014 May 16;267:67-82. PubMed PMID: 24583035; PubMed Central PMCID: PMC3998911.

                  Sinnett-Smith J, Ni Y, Wang J, Ming M, Young SH, Rozengurt E. Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling. American journal of physiology. Cell physiology. 2014 May 15;306(10):C961-71. PubMed PMID: 24647541; PubMed Central PMCID: PMC4024715.

                  Chen W, Walwyn W, Ennes HS, Kim H, McRoberts JA, Marvizón JC. BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals. The European journal of neuroscience. 2014 May;39(9):1439-54. PubMed PMID: 24611998; PubMed Central PMCID: PMC4122572.

                  Kilpatrick LA, Coveleskie K, Connolly L, Labus JS, Ebrat B, Stains J, Jiang Z, Suyenobu BY, Raybould HE, Tillisch K, Mayer EA. Influence of sucrose ingestion on brainstem and hypothalamic intrinsic oscillations in lean and obese women. Gastroenterology. 2014 May;146(5):1212-21. PubMed PMID: 24480616; PubMed Central PMCID: PMC4113508.

                  Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle. Virology. 2014 April;454-455:118-27. PubMed PMID: 24725938; PubMed Central PMCID: PMC4011396.

                  Mulak A, Taché Y, Larauche M. Sex hormones in the modulation of irritable bowel syndrome. World journal of gastroenterology. 2014 March 14;20(10):2433-48. PubMed PMID: 24627581; PubMed Central PMCID: PMC3949254.

                  Du S, Itoh N, Askarinam S, Hill H, Arnold AP, Voskuhl RR. XY sex chromosome complement, compared with XX, in the CNS confers greater neurodegeneration during experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 2014 February 18;111(7):2806-11. PubMed PMID: 24550311; PubMed Central PMCID: PMC3932937.

                  Abad C, Nobuta H, Li J, Kasai A, Yong WH, Waschek JA. Targeted STAT3 disruption in myeloid cells alters immunosuppressor cell abundance in a murine model of spontaneous medulloblastoma. Journal of leukocyte biology. 2014 February;95(2):357-67. PubMed PMID: 24068730; PubMed Central PMCID: PMC3896661.

                  Goebel-Stengel M, Stengel A, Wang L, Taché Y. Orexigenic response to tail pinch: role of brain NPY(1) and corticotropin releasing factor receptors. American journal of physiology. Regulatory, integrative and comparative physiology. 2014 February 1;306(3):R164-74. PubMed PMID: 24338440; PubMed Central PMCID: PMC3921301.

                  Young SH, Rey O, Sinnett-Smith J, Rozengurt E. Intracellular Ca2+ oscillations generated via the Ca2+-sensing receptor are mediated by negative feedback by PKCα at Thr888. American journal of physiology. Cell physiology. 2014 February 1;306(3):C298-306. PubMed PMID: 24336654; PubMed Central PMCID: PMC3919994.

                  Taylor BK, Fu W, Kuphal KE, Stiller CO, Winter MK, Chen W, Corder GF, Urban JH, McCarson KE, Marvizon JC. Inflammation enhances Y1 receptor signaling, neuropeptide Y-mediated inhibition of hyperalgesia, and substance P release from primary afferent neurons. Neuroscience. 2014 January 3;256:178-94. PubMed PMID: 24184981; PubMed Central PMCID: PMC4363128.

                  Duraffourd C, Kumala E, Anselmi L, Brecha NC, Sternini C. Opioid-induced mitogen-activated protein kinase signaling in rat enteric neurons following chronic morphine treatment. PloS one. 2014;9(10):e110230. PubMed PMID: 25302800; PubMed Central PMCID: PMC4193881.

                  Edderkaoui M, Eibl G. Risk factors for pancreatic cancer: underlying mechanisms and potential targets. Frontiers in physiology. 2014;5:490. PubMed PMID: 25540626; PubMed Central PMCID: PMC4261721.

                  Ghahramani NM, Ngun TC, Chen PY, Tian Y, Krishnan S, Muir S, Rubbi L, Arnold AP, de Vries GJ, Forger NG, Pellegrini M, Vilain E. The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging. Biology of sex differences. 2014;5:8. PubMed PMID: 24976947; PubMed Central PMCID: PMC4074311.

                  Gong J, Robbins LA, Lugea A, Waldron RT, Jeon CY, Pandol SJ. Diabetes, pancreatic cancer, and metformin therapy. Frontiers in physiology. 2014;5:426. PubMed PMID: 25426078; PubMed Central PMCID: PMC4224068.

                  Jabaji Z, Brinkley GJ, Khalil HA, Sears CM, Lei NY, Lewis M, Stelzner M, Martín MG, Dunn JC. Type I collagen as an extracellular matrix for the in vitro growth of human small intestinal epithelium. PloS one. 2014;9(9):e107814. PubMed PMID: 25222024; PubMed Central PMCID: PMC4164635.

                  Karagiannides I, Golovatscka V, Bakirtzi K, Sideri A, Salas M, Stavrakis D, Polytarchou C, Iliopoulos D, Pothoulakis C, Bradesi S. Chronic unpredictable stress regulates visceral adipocyte-mediated glucose metabolism and inflammatory circuits in male rats. Physiological reports. 2014;2(5):e00284. PubMed PMID: 24819750; PubMed Central PMCID: PMC4098730.

                  Labus JS, Dinov ID, Jiang Z, Ashe-McNalley C, Zamanyan A, Shi Y, Hong JY, Gupta A, Tillisch K, Ebrat B, Hobel S, Gutman BA, Joshi S, Thompson PM, Toga AW, Mayer EA. Irritable bowel syndrome in female patients is associated with alterations in structural brain networks. Pain. 2014 January;155(1):137-49. PubMed PMID: 24076048; PubMed Central PMCID: PMC4100785.

                  Lei NY, Jabaji Z, Wang J, Joshi VS, Brinkley GJ, Khalil H, Wang F, Jaroszewicz A, Pellegrini M, Li L, Lewis M, Stelzner M, Dunn JC, Martín MG. Intestinal subepithelial myofibroblasts support the growth of intestinal epithelial stem cells. PloS one. 2014;9(1):e84651. PubMed PMID: 24400106; PubMed Central PMCID: PMC3882257.

                  Lu QY, Zhang L, Eibl G, Go VL. Overestimation of flavonoid aglycones as a result of the ex vivo deconjugation of glucuronides by the tissue β-glucuronidase. Journal of pharmaceutical and biomedical analysis. 2014 January;88:364-9. PubMed PMID: 24176739; PubMed Central PMCID: PMC3882034.

                  Ming M, Sinnett-Smith J, Wang J, Soares HP, Young SH, Eibl G, Rozengurt E. Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. PloS one. 2014;9(12):e114573. PubMed PMID: 25493642; PubMed Central PMCID: PMC4262417.

                  Richardson-Harman N, Hendrix CW, Bumpus NN, Mauck C, Cranston RD, Yang K, Elliott J, Tanner K, McGowan I, Kashuba A, Anton PA. Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study. PloS one. 2014;9(10):e111507. PubMed PMID: 25350130; PubMed Central PMCID: PMC4211741.

                  Rozengurt E. Mechanistic target of rapamycin (mTOR): a point of convergence in the action of insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer cells. Frontiers in physiology. 2014;5:357. PubMed PMID: 25295009; PubMed Central PMCID: PMC4171984.

                  Stengel A, Taché Y. CRF and urocortin peptides as modulators of energy balance and feeding behavior during stress. Frontiers in neuroscience. 2014;8:52. PubMed PMID: 24672423; PubMed Central PMCID: PMC3957495.

                  Su AM, Shih W, Presson AP, Chang L. Characterization of symptoms in irritable bowel syndrome with mixed bowel habit pattern. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 January;26(1):36-45. PubMed PMID: 23991913; PubMed Central PMCID: PMC3865067.

                  Vegezzi G, Anselmi L, Huynh J, Barocelli E, Rozengurt E, Raybould H, Sternini C. Diet-induced regulation of bitter taste receptor subtypes in the mouse gastrointestinal tract. PloS one. 2014;9(9):e107732. PubMed PMID: 25238152; PubMed Central PMCID: PMC4169553.

                  Vu JP, Million M, Larauche M, Luong L, Norris J, Waschek JA, Pothoulakis C, Pisegna JR, Germano PM. Inhibition of vasoactive intestinal polypeptide (VIP) induces resistance to dextran sodium sulfate (DSS)-induced colitis in mice. Journal of molecular neuroscience : MN. 2014 January;52(1):37-47. PubMed PMID: 24395090; PubMed Central PMCID: PMC4114158.

                  Zhou G, Sinnett-Smith J, Liu SH, Yu J, Wu J, Sanchez R, Pandol SJ, Abrol R, Nemunaitis J, Rozengurt E, Brunicardi FC. Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin. Frontiers in physiology. 2014;5:226. PubMed PMID: 25009500; PubMed Central PMCID: PMC4069483.

                  Ke B, Shen XD, Zhang Y, Ji H, Gao F, Yue S, Kamo N, Zhai Y, Yamamoto M, Busuttil RW, Kupiec-Weglinski JW. KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants. Journal of hepatology. 2013 December;59(6):1200-7. PubMed PMID: 23867319; PubMed Central PMCID: PMC4524560.

                  Marcus EA, Vagin O, Tokhtaeva E, Sachs G, Scott DR. Helicobacter pylori impedes acid-induced tightening of gastric epithelial junctions. American journal of physiology. Gastrointestinal and liver physiology. 2013 November 15;305(10):G731-9. PubMed PMID: 23989011; PubMed Central PMCID: PMC3840231.

                  Cheng P, Shih W, Alberto M, Presson AP, Licudine A, Mayer EA, Naliboff BD, Chang L. Autonomic response to a visceral stressor is dysregulated in irritable bowel syndrome and correlates with duration of disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2013 October;25(10):e650-9. PubMed PMID: 23822743; PubMed Central PMCID: PMC3788031.

                  Dawson DW, Hertzer K, Moro A, Donald G, Chang HH, Go VL, Pandol SJ, Lugea A, Gukovskaya AS, Li G, Hines OJ, Rozengurt E, Eibl G. High-fat, high-calorie diet promotes early pancreatic neoplasia in the conditional KrasG12D mouse model. Cancer prevention research (Philadelphia, Pa.). 2013 October;6(10):1064-73. PubMed PMID: 23943783; PubMed Central PMCID: PMC3835151.

                  Connolly L, Coveleskie K, Kilpatrick LA, Labus JS, Ebrat B, Stains J, Jiang Z, Tillisch K, Raybould HE, Mayer EA. Differences in brain responses between lean and obese women to a sweetened drink. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2013 July;25(7):579-e460. PubMed PMID: 23566308; PubMed Central PMCID: PMC4114731.

                  Kisfalvi K, Moro A, Sinnett-Smith J, Eibl G, Rozengurt E. Metformin inhibits the growth of human pancreatic cancer xenografts. Pancreas. 2013 July;42(5):781-5. PubMed PMID: 23462329; PubMed Central PMCID: PMC3681894.

                  Sinnett-Smith J, Kisfalvi K, Kui R, Rozengurt E. Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK. Biochemical and biophysical research communications. 2013 January 4;430(1):352-7. PubMed PMID: 23159620; PubMed Central PMCID: PMC3545113.

                  Waldron RT, Innamorati G, Torres-Marquez ME, Sinnett-Smith J, Rozengurt E. Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq. Cellular signalling. 2012 April;24(4):914-21. PubMed PMID: 22227248; PubMed Central PMCID: PMC3286641.

                  Goebel-Stengel M, Stengel A, Taché Y, Reeve JR Jr. The importance of using the optimal plasticware and glassware in studies involving peptides. Analytical biochemistry. 2011 July 1;414(1):38-46. PubMed PMID: 21315060; PubMed Central PMCID: PMC3290000.

                  Rozengurt E. Protein kinase D signaling: multiple biological functions in health and disease. Physiology (Bethesda, Md.). 2011 February;26(1):23-33. PubMed PMID: 21357900; PubMed Central PMCID: PMC4381749.

                  Guha S, Tanasanvimon S, Sinnett-Smith J, Rozengurt E. Role of protein kinase D signaling in pancreatic cancer. Biochemical pharmacology. 2010 December 15;80(12):1946-54. PubMed PMID: 20621068; PubMed Central PMCID: PMC2974013.

                  Young SH, Rozengurt E. Crosstalk between insulin receptor and G protein-coupled receptor signaling systems leads to Ca²+ oscillations in pancreatic cancer PANC-1 cells. Biochemical and biophysical research communications. 2010 October 8;401(1):154-8. PubMed PMID: 20849815; PubMed Central PMCID: PMC2952715.

                  Harikumar KB, Kunnumakkara AB, Ochi N, Tong Z, Deorukhkar A, Sung B, Kelland L, Jamieson S, Sutherland R, Raynham T, Charles M, Bagherzadeh A, Foxton C, Boakes A, Farooq M, Maru D, Diagaradjane P, Matsuo Y, Sinnett-Smith J, Gelovani J, Krishnan S, Aggarwal BB, Rozengurt E, Ireson CR, Guha S. A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo. Molecular cancer therapeutics. 2010 May;9(5):1136-46. PubMed PMID: 20442301; PubMed Central PMCID: PMC2905628.

                  Kisfalvi K, Hurd C, Guha S, Rozengurt E. Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells. Journal of cellular physiology. 2010 May;223(2):309-16. PubMed PMID: 20082306; PubMed Central PMCID: PMC2888293.

                  Rozengurt E, Sinnett-Smith J, Kisfalvi K. Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2010 May 1;16(9):2505-11. PubMed PMID: 20388847; PubMed Central PMCID: PMC2862089.

                  Weinberg BM, Spiegel BM, Tomlinson JS, Farrell JJ. Asymptomatic pancreatic cystic neoplasms: maximizing survival and quality of life using Markov-based clinical nomograms. Gastroenterology. 2010 February;138(2):531-40. PubMed PMID: 19818780; PubMed Central PMCID: PMC2949077.

                  Torres-Marquez E, Sinnett-Smith J, Guha S, Kui R, Waldron RT, Rey O, Rozengurt E. CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway. Biochemical and biophysical research communications. 2010 January 1;391(1):63-8. PubMed PMID: 19896460; PubMed Central PMCID: PMC2812606.

                  Correction: A Novel Small-Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In vitro and In vivo. Molecular cancer therapeutics. 2010. PubMed Central PMCID: PMC2940835.

                  Jiang X, Sinnett-Smith J, Rozengurt E. Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. Biochemical and biophysical research communications. 2009 September 25;387(3):521-4. PubMed PMID: 19615971; PubMed Central PMCID: PMC2754135.

                  Kisfalvi K, Eibl G, Sinnett-Smith J, Rozengurt E. Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer research. 2009 August 15;69(16):6539-45. PubMed PMID: 19679549; PubMed Central PMCID: PMC2753241.

                  Spiegel BM, Farid M, van Oijen MG, Laine L, Howden CW, Esrailian E. Adherence to best practice guidelines in dyspepsia: a survey comparing dyspepsia experts, community gastroenterologists and primary-care providers. Alimentary pharmacology & therapeutics. 2009 April 15;29(8):871-81. PubMed PMID: 19183152; PubMed Central PMCID: PMC2953468.

                  Desai AA, Bolus R, Nissenson A, Chertow GM, Bolus S, Solomon MD, Khawar OS, Talley J, Spiegel BM. Is there "cherry picking" in the ESRD Program? Perceptions from a Dialysis Provider Survey. Clinical journal of the American Society of Nephrology : CJASN. 2009 April;4(4):772-7. PubMed PMID: 19339407; PubMed Central PMCID: PMC2666440.

                  Spiegel BM, Chey WD, Chang L. Bacterial overgrowth and irritable bowel syndrome: unifying hypothesis or a spurious consequence of proton pump inhibitors?. The American journal of gastroenterology. 2008 December;103(12):2972-6. PubMed PMID: 19086951; PubMed Central PMCID: PMC2949084.

                  Angst E, Reber HA, Hines OJ, Eibl G. Mononuclear cell-derived interleukin-1 beta confers chemoresistance in pancreatic cancer cells by upregulation of cyclooxygenase-2. Surgery. 2008 July;144(1):57-65. PubMed PMID: 18571585; PubMed Central PMCID: PMC2601479.

                  Rozengurt E, Sternini C. Taste receptor signaling in the mammalian gut. Current opinion in pharmacology. 2007 December;7(6):557-62. PubMed PMID: 18024184; PubMed Central PMCID: PMC2753238.

                  McConalogue K, Grady EF, Minnis J, Balestra B, Tonini M, Brecha NC, Bunnett NW, Sternini C. Activation and internalization of the mu-opioid receptor by the newly discovered endogenous agonists, endomorphin-1 and endomorphin-2. Neuroscience. 1999 March;90(3):1051-9. PubMed PMID: 10218804; PubMed Central PMCID: PMC4472477

  Condro MC, Matynia A, Foster NN, Ago Y, Rajbhandari AK, Van C, Jayaram B, Parikh S, Diep AL, Nguyen E, May V, Dong HW, Waschek JA. High-resolution characterization of a PACAP-EGFP transgenic mouse model for mapping PACAP-expressing neurons. The Journal of comparative neurology. 2016 December 15;524(18):3827-3848. PubMed PMID: 27197019; PubMed Central PMCID: PMC5063673.

                  Duboc H, Tolstanova G, Yuan PQ, Wu V, Kaji I, Biraud M, Akiba Y, Kaunitz J, Million M, Tache Y, Larauche M. Reduction of epithelial secretion in male rat distal colonic mucosa by bile acid receptor TGR5 agonist, INT-777: role of submucosal neurons. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 November;28(11):1663-1676. PubMed PMID: 27259385; PubMed Central PMCID: PMC5083223.

                  Orand A, Naliboff B, Gadd M, Shih W, Ju T, Presson AP, Mayer EA, Chang L. Corticotropin-releasing hormone receptor 1 (CRH-R1) polymorphisms are associated with irritable bowel syndrome and acoustic startle response. Psychoneuroendocrinology. 2016 November;73:133-141. PubMed PMID: 27497153; PubMed Central PMCID: PMC5048544.

                  Koon HW, Su B, Xu C, Mussatto CC, Tran DH, Lee EC, Ortiz C, Wang J, Lee JE, Ho S, Chen X, Kelly CP, Pothoulakis C. Probiotic Saccharomyces boulardii CNCM I-745 prevents outbreak-associated Clostridium difficile-associated cecal inflammation in hamsters. American journal of physiology. Gastrointestinal and liver physiology. 2016 October 1;311(4):G610-G623. PubMed PMID: 27514478; PubMed Central PMCID: PMC5142203.

                  Hoang-Yen Tran D, Hoang-Ngoc Tran D, Mattai SA, Sallam T, Ortiz C, Lee EC, Robbins L, Ho S, Lee JE, Fisseha E, Shieh C, Sideri A, Shih DQ, Fleshner P, McGovern DP, Vu M, Hing TC, Bakirtzi K, Cheng M, Su B, Law I, Karagiannides I, Targan SR, Gallo RL, Li Z, Koon HW. Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. International journal of obesity (2005). 2016 September;40(9):1424-34. PubMed PMID: 27163748; PubMed Central PMCID: PMC5014693.

                  Million M, Larauche M. Stress, sex, and the enteric nervous system. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 September;28(9):1283-9. PubMed PMID: 27561694; PubMed Central PMCID: PMC5003424.

                  Padua D, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih D, Iliopoulos D, Pothoulakis C. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. American journal of physiology. Gastrointestinal and liver physiology. 2016 September 1;311(3):G446-57. PubMed PMID: 27492330; PubMed Central PMCID: PMC5076004.

                  Wang J, Sinnett-Smith J, Stevens JV, Young SH, Rozengurt E. Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD). The Journal of biological chemistry. 2016 August 19;291(34):17988-8005. PubMed PMID: 27369082; PubMed Central PMCID: PMC5016186.

                  Park SH, Videlock EJ, Shih W, Presson AP, Mayer EA, Chang L. Adverse childhood experiences are associated with irritable bowel syndrome and gastrointestinal symptom severity. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 August;28(8):1252-60. PubMed PMID: 27061107; PubMed Central PMCID: PMC4956522.

                  Antonios JP, Soto H, Everson RG, Orpilla J, Moughon D, Shin N, Sedighim S, Yong WH, Li G, Cloughesy TF, Liau LM, Prins RM. PD-1 blockade enhances the vaccination-induced immune response in glioma. JCI insight. 2016 July 7;1(10). PubMed PMID: 27453950; PubMed Central PMCID: PMC4951098.

                  Khalil HA, Lei NY, Brinkley G, Scott A, Wang J, Kar UK, Jabaji ZB, Lewis M, Martín MG, Dunn JC, Stelzner MG. A novel culture system for adult porcine intestinal crypts. Cell and tissue research. 2016 July;365(1):123-34. PubMed PMID: 26928041; PubMed Central PMCID: PMC4919165.

                  Videlock EJ, Shih W, Adeyemo M, Mahurkar-Joshi S, Presson AP, Polytarchou C, Alberto M, Iliopoulos D, Mayer EA, Chang L. The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression. Psychoneuroendocrinology. 2016 July;69:67-76. PubMed PMID: 27038676; PubMed Central PMCID: PMC4977028.

                  Kaji I, Akiba Y, Konno K, Watanabe M, Kimura S, Iwanaga T, Kuri A, Iwamoto K, Kuwahara A, Kaunitz JD. Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon. The Journal of physiology. 2016 June 15;594(12):3339-52. PubMed PMID: 26854275; PubMed Central PMCID: PMC4908031.

                  Holschneider DP, Guo Y, Mayer EA, Wang Z. Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats. Neurobiology of stress. 2016 June 1;3:8-22. PubMed PMID: 26751119; PubMed Central PMCID: PMC4700548.

                  Padua D, Vu JP, Germano PM, Pisegna JR. The Role of Neuropeptides in Mouse Models of Colitis. Journal of molecular neuroscience : MN. 2016 June;59(2):203-10. PubMed PMID: 26646243; PubMed Central PMCID: PMC4884658.

                  Scott A, Rouch JD, Jabaji Z, Khalil HA, Solorzano S, Lewis M, Martín MG, Stelzner MG, Dunn JC. Long-term renewable human intestinal epithelial stem cells as monolayers: A potential for clinical use. Journal of pediatric surgery. 2016 June;51(6):995-1000. PubMed PMID: 26995514; PubMed Central PMCID: PMC4921284.

                  Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. 2016 June;159(6):1520-1527. PubMed PMID: 26847803; PubMed Central PMCID: PMC4856542.

                  Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. American journal of physiology. Gastrointestinal and liver physiology. 2016 June 1;310(11):G1124-37. PubMed PMID: 27151939; PubMed Central PMCID: PMC5005285.

                  Yu J, Liu SH, Sanchez R, Nemunaitis J, Rozengurt E, Brunicardi FC. PDX1 associated therapy in translational medicine. Annals of translational medicine. 2016 June;4(11):214. PubMed PMID: 27386488; PubMed Central PMCID: PMC4916355.

                  Bakirtzi K, Law IK, Xue X, Iliopoulos D, Shah YM, Pothoulakis C. Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling. Journal of immunology (Baltimore, Md. : 1950). 2016 May 15;196(10):4311-21. PubMed PMID: 27076683; PubMed Central PMCID: PMC4868643.

                  Deriu E, Boxx GM, He X, Pan C, Benavidez SD, Cen L, Rozengurt N, Shi W, Cheng G. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS pathogens. 2016 May;12(5):e1005572. PubMed PMID: 27149619; PubMed Central PMCID: PMC4858270.

                  Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Molecular cancer research : MCR. 2016 May;14(5):437-47. PubMed PMID: 26979711; PubMed Central PMCID: PMC4867256.

                  Vorvis C, Koutsioumpa M, Iliopoulos D. Developments in miRNA gene signaling pathways in pancreatic cancer. Future oncology (London, England). 2016 May;12(9):1135-50. PubMed PMID: 26984178; PubMed Central PMCID: PMC5551925.

                  Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Science translational medicine. 2016 April 13;8(334):334ra54. PubMed PMID: 27075628; PubMed Central PMCID: PMC4934679.

                  Ackerman AL, Jellison FC, Lee UJ, Bradesi S, Rodríguez LV. The Glt1 glutamate receptor mediates the establishment and perpetuation of chronic visceral pain in an animal model of stress-induced bladder hyperalgesia. American journal of physiology. Renal physiology. 2016 April 1;310(7):F628-F636. PubMed PMID: 26697981; PubMed Central PMCID: PMC5504462.

                  Gupta A, Labus J, Kilpatrick LA, Bonyadi M, Ashe-McNalley C, Heendeniya N, Bradesi S, Chang L, Mayer EA. Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females. Brain structure & function. 2016 April;221(3):1667-79. PubMed PMID: 25630611; PubMed Central PMCID: PMC4573367.

                  Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly. International journal of antimicrobial agents. 2016 April;47(4):289-96. PubMed PMID: 27013001; PubMed Central PMCID: PMC4833571.

                  Wang J, Han L, Sinnett-Smith J, Han LL, Stevens JV, Rozengurt N, Young SH, Rozengurt E. Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552. American journal of physiology. Cell physiology. 2016 April 1;310(7):C542-57. PubMed PMID: 26739494; PubMed Central PMCID: PMC4824155.

                  Yuan PQ, Wu SV, Pothoulakis C, Taché Y. Urocortins and CRF receptor type 2 variants in the male rat colon: gene expression and regulation by endotoxin and anti-inflammatory effect. American journal of physiology. Gastrointestinal and liver physiology. 2016 March 15;310(6):G387-98. PubMed PMID: 26744472; PubMed Central PMCID: PMC4796293.

                  Hertzer KM, Xu M, Moro A, Dawson DW, Du L, Li G, Chang HH, Stark AP, Jung X, Hines OJ, Eibl G. Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer. Pancreas. 2016 March;45(3):458-65. PubMed PMID: 26495779; PubMed Central PMCID: PMC4854638.

                  Mahurkar S, Polytarchou C, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 March;28(3):410-22. PubMed PMID: 26670691; PubMed Central PMCID: PMC4760882.

                  Law IK, Jensen D, Bunnett NW, Pothoulakis C. Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin. Scientific reports. 2016 February 23;6:22195. PubMed PMID: 26902265; PubMed Central PMCID: PMC4763298.

                  Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi K, Dulai GS, Machicado GA. Natural history of definitive diverticular hemorrhage based on stigmata of recent hemorrhage and colonoscopic Doppler blood flow monitoring for risk stratification and definitive hemostasis. Gastrointestinal endoscopy. 2016 February;83(2):416-23. PubMed PMID: 26227931; PubMed Central PMCID: PMC4715947.

                  Walwyn WM, Chen W, Kim H, Minasyan A, Ennes HS, McRoberts JA, Marvizón JC. Sustained Suppression of Hyperalgesia during Latent Sensitization by μ-, δ-, and κ-opioid receptors and α2A Adrenergic Receptors: Role of Constitutive Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2016 January 6;36(1):204-21. PubMed PMID: 26740662; PubMed Central PMCID: PMC4701961.

                  Birtolo C, Go VL, Ptasznik A, Eibl G, Pandol SJ. Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas. 2016 January;45(1):21-31. PubMed PMID: 26658038; PubMed Central PMCID: PMC4859755.

                  Camus M, Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi KA, Machicado GA, Dulai GS, Jensen ME, Gornbein JA. Comparison of Three Risk Scores to Predict Outcomes of Severe Lower Gastrointestinal Bleeding. Journal of clinical gastroenterology. 2016 January;50(1):52-8. PubMed PMID: 25599218; PubMed Central PMCID: PMC4504830.

                  Hoffman JM, Baritaki S, Ruiz JJ, Sideri A, Pothoulakis C. Corticotropin-Releasing Hormone Receptor 2 Signaling Promotes Mucosal Repair Responses after Colitis. The American journal of pathology. 2016 January;186(1):134-44. PubMed PMID: 26597886; PubMed Central PMCID: PMC4714033.

                  Hong JY, Naliboff B, Labus JS, Gupta A, Kilpatrick LA, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Mayer EA. Altered brain responses in subjects with irritable bowel syndrome during cued and uncued pain expectation. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 January;28(1):127-38. PubMed PMID: 26526698; PubMed Central PMCID: PMC4943658.

                  Jarcho JM, Feier NA, Labus JS, Naliboff B, Smith SR, Hong JY, Colloca L, Tillisch K, Mandelkern MA, Mayer EA, London ED. Placebo analgesia: Self-report measures and preliminary evidence of cortical dopamine release associated with placebo response. NeuroImage. Clinical. 2016;10:107-14. PubMed PMID: 26759785; PubMed Central PMCID: PMC4683423.

                  Jensen DM, Ohning GV, Kovacs TO, Ghassemi KA, Jutabha R, Dulai GS, Machicado GA. Doppler endoscopic probe as a guide to risk stratification and definitive hemostasis of peptic ulcer bleeding. Gastrointestinal endoscopy. 2016 January;83(1):129-36. PubMed PMID: 26318834; PubMed Central PMCID: PMC4691549.

                  Labus JS, Naliboff B, Kilpatrick L, Liu C, Ashe-McNalley C, dos Santos IR, Alaverdyan M, Woodworth D, Gupta A, Ellingson BM, Tillisch K, Mayer EA. Pain and Interoception Imaging Network (PAIN): A multimodal, multisite, brain-imaging repository for chronic somatic and visceral pain disorders. NeuroImage. 2016 January 1;124(Pt B):1232-7. PubMed PMID: 25902408; PubMed Central PMCID: PMC4627849.

                  Latorre R, Huynh J, Mazzoni M, Gupta A, Bonora E, Clavenzani P, Chang L, Mayer EA, De Giorgio R, Sternini C. Expression of the Bitter Taste Receptor, T2R38, in Enteroendocrine Cells of the Colonic Mucosa of Overweight/Obese vs. Lean Subjects. PloS one. 2016;11(2):e0147468. PubMed PMID: 26866366; PubMed Central PMCID: PMC4750998.

                  Moussaoui N, Larauche M, Biraud M, Molet J, Million M, Mayer E, Taché Y. Limited Nesting Stress Alters Maternal Behavior and In Vivo Intestinal Permeability in Male Wistar Pup Rats. PloS one. 2016;11(5):e0155037. PubMed PMID: 27149676; PubMed Central PMCID: PMC4858303.

                  Rouch JD, Scott A, Lei NY, Solorzano-Vargas RS, Wang J, Hanson EM, Kobayashi M, Lewis M, Stelzner MG, Dunn JC, Eckmann L, Martín MG. Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. PloS one. 2016;11(1):e0148216. PubMed PMID: 26820624; PubMed Central PMCID: PMC4731053.

                  Zhou G, Yu J, Wang A, Liu SH, Sinnett-Smith J, Wu J, Sanchez R, Nemunaitis J, Ricordi C, Rozengurt E, Brunicardi FC. Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma. Current molecular medicine. 2016;16(1):83-90. PubMed PMID: 26695692; PubMed Central PMCID: PMC4994969.

                  Vuong HE, Hardi CN, Barnes S, Brecha NC. Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 December 2;35(48):15955-70. PubMed PMID: 26631476; PubMed Central PMCID: PMC4666919.

                  Kilpatrick LA, Istrin JJ, Gupta A, Naliboff BD, Tillisch K, Labus JS, Mayer EA. Sex commonalities and differences in the relationship between resilient personality and the intrinsic connectivity of the salience and default mode networks. Biological psychology. 2015 December;112:107-15. PubMed PMID: 26440126; PubMed Central PMCID: PMC5012423.

                  Phan J, Benhammou JN, Pisegna JR. Gastric Hypersecretory States: Investigation and Management. Current treatment options in gastroenterology. 2015 December;13(4):386-97. PubMed PMID: 26342486; PubMed Central PMCID: PMC4633316.

                  Stark AP, Chang HH, Jung X, Moro A, Hertzer K, Xu M, Schmidt A, Hines OJ, Eibl G. E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice. Surgery. 2015 December;158(6):1564-72. PubMed PMID: 26297056; PubMed Central PMCID: PMC4637247.

                  Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of experimental medicine. 2015 November 16;212(12):2147-63. PubMed PMID: 26552708; PubMed Central PMCID: PMC4647265.

                  Chang HH, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G. Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1. American journal of physiology. Cell physiology. 2015 November 15;309(10):C639-49. PubMed PMID: 26310818; PubMed Central PMCID: PMC4652080.

                  Vu JP, Goyal D, Luong L, Oh S, Sandhu R, Norris J, Parsons W, Pisegna JR, Germano PM. PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin. American journal of physiology. Gastrointestinal and liver physiology. 2015 November 15;309(10):G816-25. PubMed PMID: 26336928; PubMed Central PMCID: PMC4652141.

                  Young SH, Rey O, Rozengurt E. Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: Impact of the highly conservative mutation Ser170Thr. Biochemical and biophysical research communications. 2015 November 6;467(1):1-6. PubMed PMID: 26431875; PubMed Central PMCID: PMC4613767.

                  Rodriguez JA, Huerta-Yepez S, Law IK, Baay-Guzman GJ, Tirado-Rodriguez B, Hoffman JM, Iliopoulos D, Hommes DW, Verspaget HW, Chang L, Pothoulakis C, Baritaki S. Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling. Cellular and molecular gastroenterology and hepatology. 2015 November 1;1(6):610-630. PubMed PMID: 26495412; PubMed Central PMCID: PMC4610032.

                  Vuong HE, Pérez de Sevilla Müller L, Hardi CN, McMahon DG, Brecha NC. Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines. Neuroscience. 2015 October 29;307:319-37. PubMed PMID: 26335381; PubMed Central PMCID: PMC4603663.

                  Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D. MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice. Gastroenterology. 2015 October;149(4):981-92.e11. PubMed PMID: 26055138; PubMed Central PMCID: PMC4584179.

                  Fang K, Sideri A, Law IK, Bakirtzi K, Polytarchou C, Iliopoulos D, Pothoulakis C. Identification of a novel substance P (SP)-neurokinin-1 receptor (NK-1R) microRNA-221-5p inflammatory network in human colonic epithelial cells. Cellular and molecular gastroenterology and hepatology. 2015 September 1;1(5):503-515. PubMed PMID: 26645045; PubMed Central PMCID: PMC4669978.

                  Hubbard CS, Hong J, Jiang Z, Ebrat B, Suyenobu B, Smith S, Heendeniya N, Naliboff BD, Tillisch K, Mayer EA, Labus JS. Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 September;27(9):1282-94. PubMed PMID: 26087779; PubMed Central PMCID: PMC4550526.

                  Cherukuri DP, Deignan JL, Das K, Grody WW, Herschman H. Instability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma. Molecular oncology. 2015 August;9(7):1252-8. PubMed PMID: 25817443; PubMed Central PMCID: PMC4523444.

                  Irimia A, Labus JS, Torgerson CM, Van Horn JD, Mayer EA. Altered viscerotopic cortical innervation in patients with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 August;27(8):1075-81. PubMed PMID: 25952540; PubMed Central PMCID: PMC4520752.

                  Kaunitz JD. The Discovery of PCR: ProCuRement of Divine Power. Digestive diseases and sciences. 2015 August;60(8):2230-1. PubMed PMID: 26077976; PubMed Central PMCID: PMC4501591.

                  Kobayashi M, Lei NY, Wang Q, Wu BM, Dunn JC. Orthogonally oriented scaffolds with aligned fibers for engineering intestinal smooth muscle. Biomaterials. 2015 August;61:75-84. PubMed PMID: 26001072; PubMed Central PMCID: PMC4464968.

                  Labus JS, Van Horn JD, Gupta A, Alaverdyan M, Torgerson C, Ashe-McNalley C, Irimia A, Hong JY, Naliboff B, Tillisch K, Mayer EA. Multivariate morphological brain signatures predict patients with chronic abdominal pain from healthy control subjects. Pain. 2015 August;156(8):1545-54. PubMed PMID: 25906347; PubMed Central PMCID: PMC4504800.

                  O'Mahony F, Wroblewski K, O'Byrne SM, Jiang H, Clerkin K, Benhammou J, Blaner WS, Beaven SW. Liver X receptors balance lipid stores in hepatic stellate cells through Rab18, a retinoid responsive lipid droplet protein. Hepatology (Baltimore, Md.). 2015 August;62(2):615-26. PubMed PMID: 25482505; PubMed Central PMCID: PMC4458237.

                  Tuominen I, Beaven SW. Intestinal farnesoid X receptor puts a fresh coat of wax on fatty liver. Hepatology (Baltimore, Md.). 2015 August;62(2):646-8. PubMed PMID: 25998695; PubMed Central PMCID: PMC4523235.

                  Law IK, Bakirtzi K, Polytarchou C, Oikonomopoulos A, Hommes D, Iliopoulos D, Pothoulakis C. Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis. Gut. 2015 July;64(7):1095-104. PubMed PMID: 25112884; PubMed Central PMCID: PMC4422787.

                  Lugea A, Waldron RT, Pandol SJ. Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2015 July;15(4 Suppl):S1-5. PubMed PMID: 25736240; PubMed Central PMCID: PMC4515411.

                  Stengel A, Karasawa H, Taché Y. The role of brain somatostatin receptor 2 in the regulation of feeding and drinking behavior. Hormones and behavior. 2015 July;73:15-22. PubMed PMID: 26026616; PubMed Central PMCID: PMC4546908.

                  Sanmiguel C, Gupta A, Mayer EA. Gut Microbiome and Obesity: A Plausible Explanation for Obesity. Current obesity reports. 2015 June;4(2):250-61. PubMed PMID: 26029487; PubMed Central PMCID: PMC4443745.

                  Vu JP, Larauche M, Flores M, Luong L, Norris J, Oh S, Liang LJ, Waschek J, Pisegna JR, Germano PM. Regulation of Appetite, Body Composition, and Metabolic Hormones by Vasoactive Intestinal Polypeptide (VIP). Journal of molecular neuroscience : MN. 2015 June;56(2):377-87. PubMed PMID: 25904310; PubMed Central PMCID: PMC4458420.

                  Gupta A, Rapkin AJ, Gill Z, Kilpatrick L, Fling C, Stains J, Masghati S, Tillisch K, Mayer EA, Labus JS. Disease-related differences in resting-state networks: a comparison between localized provoked vulvodynia, irritable bowel syndrome, and healthy control subjects. Pain. 2015 May;156(5):809-19. PubMed PMID: 25735001; PubMed Central PMCID: PMC4402252.

                  Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D. A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. Inflammatory bowel diseases. 2015 May;21(5):996-1005. PubMed PMID: 25738378; PubMed Central PMCID: PMC4402238.

                  Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JC, Martin MG, Lagasse E, Zhang L, Yu J. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Scientific reports. 2015 April 10;5:8566. PubMed PMID: 25858503; PubMed Central PMCID: PMC4392360.

                  Wu JX, Liu SH, Nemunaitis JJ, Brunicardi FC. Liposomal insulin promoter-thymidine kinase gene therapy followed by ganciclovir effectively ablates human pancreatic cancer in mice. Cancer letters. 2015 April 10;359(2):206-10. PubMed PMID: 25596375; PubMed Central PMCID: PMC4336837.

                  Akiba Y, Kaunitz JD, Million M. Peripheral corticotropin-releasing factor receptor type 2 activation increases colonic blood flow through nitric oxide pathway in rats. Digestive diseases and sciences. 2015 April;60(4):858-67. PubMed PMID: 25701320; PubMed Central PMCID: PMC4501405.

                  Anselmi L, Huynh J, Duraffourd C, Jaramillo I, Vegezzi G, Saccani F, Boschetti E, Brecha NC, De Giorgio R, Sternini C. Activation of μ opioid receptors modulates inflammation in acute experimental colitis. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 April;27(4):509-23. PubMed PMID: 25690069; PubMed Central PMCID: PMC4405133.

                  Liu Z, Sun F, Braun J, McGovern DP, Piantadosi S. Multilevel regularized regression for simultaneous taxa selection and network construction with metagenomic count data. Bioinformatics (Oxford, England). 2015 April 1;31(7):1067-74. PubMed PMID: 25416747; PubMed Central PMCID: PMC4382903.

                  Marvizon JC, Walwyn W, Minasyan A, Chen W, Taylor BK. Latent sensitization: a model for stress-sensitive chronic pain. Current protocols in neuroscience. 2015 April 1;71:9.50.1-14. PubMed PMID: 25829356; PubMed Central PMCID: PMC4532319.

                  Mayer EA, Gupta A, Kilpatrick LA, Hong JY. Imaging brain mechanisms in chronic visceral pain. Pain. 2015 April;156 Suppl 1:S50-63. PubMed PMID: 25789437; PubMed Central PMCID: PMC4428597.

                  Sideri A, Stavrakis D, Bowe C, Shih DQ, Fleshner P, Arsenescu V, Arsenescu R, Turner JR, Pothoulakis C, Karagiannides I. Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1. American journal of physiology. Gastrointestinal and liver physiology. 2015 April 1;308(7):G591-604. PubMed PMID: 25591865; PubMed Central PMCID: PMC4385897.

                  Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2. Molecular cancer therapeutics. 2015 April;14(4):1014-23. PubMed PMID: 25673820; PubMed Central PMCID: PMC4394038.

                  Tarling EJ, Ahn H, de Aguiar Vallim TQ. The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2. Arteriosclerosis, thrombosis, and vascular biology. 2015 April;35(4):787-95. PubMed PMID: 25593129; PubMed Central PMCID: PMC4376635.

                  Gukovsky I, Gukovskaya AS. Impaired autophagy triggers chronic pancreatitis: lessons from pancreas-specific atg5 knockout mice. Gastroenterology. 2015 March;148(3):501-5. PubMed PMID: 25613315; PubMed Central PMCID: PMC4443443.

                  Liu Y, Ji H, Zhang Y, Shen X, Gao F, He X, Li GA, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury. Journal of hepatology. 2015 March;62(3):563-72. PubMed PMID: 25450716; PubMed Central PMCID: PMC4336640.

                  Sakanaka T, Inoue T, Yorifuji N, Iguchi M, Fujiwara K, Narabayashi K, Kakimoto K, Nouda S, Okada T, Kuramoto T, Ishida K, Abe Y, Takeuchi T, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. The effects of a TGR5 agonist and a dipeptidyl peptidase IV inhibitor on dextran sulfate sodium-induced colitis in mice. Journal of gastroenterology and hepatology. 2015 March;30 Suppl 1:60-5. PubMed PMID: 25827806; PubMed Central PMCID: PMC4874188.

                  Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. The Journal of biological chemistry. 2015 February 27;290(9):5566-81. PubMed PMID: 25468909; PubMed Central PMCID: PMC4342471.

                  Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. Septin dynamics are essential for exocytosis. The Journal of biological chemistry. 2015 February 27;290(9):5280-97. PubMed PMID: 25575596; PubMed Central PMCID: PMC4342448.

                  Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell metabolism. 2015 February 3;21(2):334-46. PubMed PMID: 25651185; PubMed Central PMCID: PMC4349439.

                  de Aguiar Vallim TQ, Tarling EJ, Ahn H, Hagey LR, Romanoski CE, Lee RG, Graham MJ, Motohashi H, Yamamoto M, Edwards PA. MAFG is a transcriptional repressor of bile acid synthesis and metabolism. Cell metabolism. 2015 February 3;21(2):298-310. PubMed PMID: 25651182; PubMed Central PMCID: PMC4317590.

                  Bromley EG, May FP, Federer L, Spiegel BM, van Oijen MG. Explaining persistent under-use of colonoscopic cancer screening in African Americans: a systematic review. Preventive medicine. 2015 February;71:40-8. PubMed PMID: 25481094; PubMed Central PMCID: PMC4329030.

                  Kaji I, Iwanaga T, Watanabe M, Guth PH, Engel E, Kaunitz JD, Akiba Y. SCFA transport in rat duodenum. American journal of physiology. Gastrointestinal and liver physiology. 2015 February 1;308(3):G188-97. PubMed PMID: 25394661; PubMed Central PMCID: PMC4312951.

                  Nguyen AH, Toste PA, Farrell JJ, Clerkin BM, Williams J, Muthusamy VR, Watson RR, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Current recommendations for surveillance and surgery of intraductal papillary mucinous neoplasms may overlook some patients with cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2015 February;19(2):258-65. PubMed PMID: 25373706; PubMed Central PMCID: PMC4305480.

                  Tan YV, Abad C, Wang Y, Lopez R, Waschek J. VPAC2 (vasoactive intestinal peptide receptor type 2) receptor deficient mice develop exacerbated experimental autoimmune encephalomyelitis with increased Th1/Th17 and reduced Th2/Treg responses. Brain, behavior, and immunity. 2015 February;44:167-175. PubMed PMID: 25305591; PubMed Central PMCID: PMC4275378.

                  Taché Y, Million M. Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia. Journal of neurogastroenterology and motility. 2015 January 31;21(1):8-24. PubMed PMID: 25611064; PubMed Central PMCID: PMC4288101.

                  Coveleskie K, Gupta A, Kilpatrick LA, Mayer ED, Ashe-McNalley C, Stains J, Labus JS, Mayer EA. Altered functional connectivity within the central reward network in overweight and obese women. Nutrition & diabetes. 2015 January 19;5:e148. PubMed PMID: 25599560; PubMed Central PMCID: PMC4314578.

                  Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology. 2015 January 15;475:46-55. PubMed PMID: 25462345; PubMed Central PMCID: PMC4284078.

                  Abad C, Cheung-Lau G, Coûté-Monvoisin AC, Waschek JA. Vasoactive intestinal peptide-deficient mice exhibit reduced pathology in trinitrobenzene sulfonic acid-induced colitis. Neuroimmunomodulation. 2015;22(3):203-12. PubMed PMID: 25301381; PubMed Central PMCID: PMC4297532.

                  Bradesi S, Karagiannides I, Bakirtzi K, Joshi SM, Koukos G, Iliopoulos D, Pothoulakis C, Mayer EA. Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat. PloS one. 2015;10(7):e0130938. PubMed PMID: 26222740; PubMed Central PMCID: PMC4519289.

                  Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. Journal of Alzheimer's disease : JAD. 2015;43(3):967-76. PubMed PMID: 25125464; PubMed Central PMCID: PMC4258165.

                  Chen R, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM, Maitra A, Brentnall TA. Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. Laboratory investigation; a journal of technical methods and pathology. 2015 January;95(1):43-55. PubMed PMID: 25347153; PubMed Central PMCID: PMC4281293.

                  Cheng M, Ho S, Yoo JH, Tran DH, Bakirtzi K, Su B, Tran DH, Kubota Y, Ichikawa R, Koon HW. Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts. Clinical and experimental gastroenterology. 2015;8:13-29. PubMed PMID: 25565877; PubMed Central PMCID: PMC4274046.

                  Gupta A, Mayer EA, Sanmiguel CP, Van Horn JD, Woodworth D, Ellingson BM, Fling C, Love A, Tillisch K, Labus JS. Patterns of brain structural connectivity differentiate normal weight from overweight subjects. NeuroImage. Clinical. 2015;7:506-17. PubMed PMID: 25737959; PubMed Central PMCID: PMC4338207.

                  Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 January 1;21(1):157-65. PubMed PMID: 25348515; PubMed Central PMCID: PMC4286535.

                  Khalil HA, Lei NY, Nie W, Lewis MS, Stelzner MG, Martín MG, Dunn JC, Yoo J. Primary Myofibroblasts Maintain Short-Term Viability following Submucosal Injection in Syngeneic, Immune-Competent Mice Utilizing Murine Colonoscopy. PloS one. 2015;10(5):e0127258. PubMed PMID: 26016485; PubMed Central PMCID: PMC4445916.

                  Kutch JJ, Yani MS, Asavasopon S, Kirages DJ, Rana M, Cosand L, Labus JS, Kilpatrick LA, Ashe-McNalley C, Farmer MA, Johnson KA, Ness TJ, Deutsch G, Harris RE, Apkarian AV, Clauw DJ, Mackey SC, Mullins C, Mayer EA. Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study. NeuroImage. Clinical. 2015;8:493-502. PubMed PMID: 26106574; PubMed Central PMCID: PMC4474411.

                  Law IK, Pothoulakis C. MicroRNA-133α regulates neurotensin-associated colonic inflammation in colonic epithelial cells and experimental colitis. RNA & disease (Houston, Tex.). 2015;2(1). PubMed PMID: 26005712; PubMed Central PMCID: PMC4441413.

                  Li Y, Go VL, Sarkar FH. The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome. Pancreas. 2015 January;44(1):1-10. PubMed PMID: 25493373; PubMed Central PMCID: PMC4264839.

                  Martinez L, Ermolova NV, Ishikawa TO, Stout DB, Herschman HR, Spencer MJ. A reporter mouse for optical imaging of inflammation in mdx muscles. Skeletal muscle. 2015;5:15. PubMed PMID: 25949789; PubMed Central PMCID: PMC4422315.

                  Marzagalli R, Scuderi S, Drago F, Waschek JA, Castorina A. Emerging Role of PACAP as a New Potential Therapeutic Target in Major Diabetes Complications. International journal of endocrinology. 2015;2015:160928. PubMed PMID: 26074958; PubMed Central PMCID: PMC4446501.

                  McGowan I, Anton PA, Elliott J, Cranston RD, Duffill K, Althouse AD, Hawkins KL, De Rosa SC. Exploring the feasibility of multi-site flow cytometric processing of gut associated lymphoid tissue with centralized data analysis for multi-site clinical trials. PloS one. 2015;10(5):e0126454. PubMed PMID: 26010577; PubMed Central PMCID: PMC4444258.

                  Mulak A, Larauche M, Biraud M, Million M, Rivier J, Taché Y. Selective agonists of somatostatin receptor subtype 1 or 2 injected peripherally induce antihyperalgesic effect in two models of visceral hypersensitivity in mice. Peptides. 2015 January;63:71-80. PubMed PMID: 25451334; PubMed Central PMCID: PMC4385413.

                  Orand A, Gupta A, Shih W, Presson AP, Hammer C, Niesler B, Heendeniya N, Mayer EA, Chang L. Catecholaminergic Gene Polymorphisms Are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome. PloS one. 2015;10(8):e0135910. PubMed PMID: 26288143; PubMed Central PMCID: PMC4546052.

                  Taché Y. Corticotrophin-releasing factor 1 activation in the central amygdale and visceral hyperalgesia. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 January;27(1):1-6. PubMed PMID: 25557223; PubMed Central PMCID: PMC4389773.

                  Wang L, Mogami S, Yakabi S, Karasawa H, Yamada C, Yakabi K, Hattori T, Taché Y. Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito. PloS one. 2015;10(9):e0139325. PubMed PMID: 26421719; PubMed Central PMCID: PMC4589401.

                  Wang Y, Yan C, Liu L, Wang W, Du H, Fan W, Lutfy K, Jiang M, Friedman TC, Liu Y. 11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue. American journal of physiology. Endocrinology and metabolism. 2015 January 1;308(1):E84-95. PubMed PMID: 25389364; PubMed Central PMCID: PMC4281684.

                  Yoo JH, Ho S, Tran DH, Cheng M, Bakirtzi K, Kukota Y, Ichikawa R, Su B, Tran DH, Hing TC, Chang I, Shih DQ, Issacson RE, Gallo RL, Fiocchi C, Pothoulakis C, Koon HW. Anti-fibrogenic effects of the anti-microbial peptide cathelicidin in murine colitis-associated fibrosis. Cellular and molecular gastroenterology and hepatology. 2015 January;1(1):55-74.e1. PubMed PMID: 25729764; PubMed Central PMCID: PMC4338438.

                  Zhu J, Lu T, Yue S, Shen X, Gao F, Busuttil RW, Kupiec-Weglinski JW, Xia Q, Zhai Y. Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation. Transplantation. 2015 January;99(1):48-55. PubMed PMID: 25340604; PubMed Central PMCID: PMC4272660.

                  Akiba Y, Kaunitz JD. Prostaglandin pathways in duodenal chemosensing. Journal of gastroenterology and hepatology. 2014 December;29 Suppl 4:93-8. PubMed PMID: 25521740; PubMed Central PMCID: PMC4451058.

                  Bagarinao E, Johnson KA, Martucci KT, Ichesco E, Farmer MA, Labus J, Ness TJ, Harris R, Deutsch G, Apkarian AV, Mayer EA, Clauw DJ, Mackey S. Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network study. Pain. 2014 December;155(12):2502-9. PubMed PMID: 25242566; PubMed Central PMCID: PMC4504202.

                  Buzzanco A, Gomez A, Rodriguez E, French BA, Tillman BA, Chang S, Ganapathy E, Junrungsee S, Zarrinpar A, Agopian VG, Naini BV, French SW Jr, French SW Sr. Digital quantitation of HCC-associated stem cell markers and protein quality control factors using tissue arrays of human liver sections. Experimental and molecular pathology. 2014 December;97(3):399-410. PubMed PMID: 25218810; PubMed Central PMCID: PMC4262606.

                  Donahue TR, Nguyen AH, Moughan J, Li L, Tatishchev S, Toste P, Farrell JJ. Stromal microRNA-21 levels predict response to 5-fluorouracil in patients with pancreatic cancer. Journal of surgical oncology. 2014 December;110(8):952-9. PubMed PMID: 25132574; PubMed Central PMCID: PMC4232442.

                  Ji H, Liu Y, Zhang Y, Shen XD, Gao F, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. T-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury. Hepatology (Baltimore, Md.). 2014 December;60(6):2052-2064. PubMed PMID: 25066922; PubMed Central PMCID: PMC4396987.

                  Karasawa H, Pietra C, Giuliano C, Garcia-Rubio S, Xu X, Yakabi S, Taché Y, Wang L. New ghrelin agonist, HM01 alleviates constipation and L-dopa-delayed gastric emptying in 6-hydroxydopamine rat model of Parkinson's disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 December;26(12):1771-82. PubMed PMID: 25327342; PubMed Central PMCID: PMC4457321.

                  Stengel A, Taché Y. Brain peptides and the modulation of postoperative gastric ileus. Current opinion in pharmacology. 2014 December;19:31-7. PubMed PMID: 24999843; PubMed Central PMCID: PMC4254047.

                  Wagner JP, Sullins VF, Dunn JC. Skin-derived precursors generate enteric-type neurons in aganglionic jejunum. Journal of pediatric surgery. 2014 December;49(12):1809-14. PubMed PMID: 25487489; PubMed Central PMCID: PMC4261145.

                  Wagner JP, Sullins VF, Khalil HA, Dunn JC. A durable model of Hirschsprung's colon. Journal of pediatric surgery. 2014 December;49(12):1804-8. PubMed PMID: 25487488; PubMed Central PMCID: PMC4261142.

                  Hong C, Marshall SM, McDaniel AL, Graham M, Layne JD, Cai L, Scotti E, Boyadjian R, Kim J, Chamberlain BT, Tangirala RK, Jung ME, Fong L, Lee R, Young SG, Temel RE, Tontonoz P. The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice. Cell metabolism. 2014 November 4;20(5):910-8. PubMed PMID: 25440061; PubMed Central PMCID: PMC4261644.

                  Tong M, Jacobs JP, McHardy IH, Braun J. Sampling of intestinal microbiota and targeted amplification of bacterial 16S rRNA genes for microbial ecologic analysis. Current protocols in immunology. 2014 November 3;107:7.41.1-11. PubMed PMID: 25367129; PubMed Central PMCID: PMC4457454.

                  Balaji K, French CT, Miller JF, Colicelli J. The RAB5-GEF function of RIN1 regulates multiple steps during Listeria monocytogenes infection. Traffic (Copenhagen, Denmark). 2014 November;15(11):1206-18. PubMed PMID: 25082076; PubMed Central PMCID: PMC4282165.

                  Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR. Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. Molecular cancer research : MCR. 2014 November;12(11):1677-88. PubMed PMID: 25063587; PubMed Central PMCID: PMC4233191.

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                  Labus JS, Dinov ID, Jiang Z, Ashe-McNalley C, Zamanyan A, Shi Y, Hong JY, Gupta A, Tillisch K, Ebrat B, Hobel S, Gutman BA, Joshi S, Thompson PM, Toga AW, Mayer EA. Irritable bowel syndrome in female patients is associated with alterations in structural brain networks. Pain. 2014 January;155(1):137-49. PubMed PMID: 24076048; PubMed Central PMCID: PMC4100785.

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                  Ming M, Sinnett-Smith J, Wang J, Soares HP, Young SH, Eibl G, Rozengurt E. Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. PloS one. 2014;9(12):e114573. PubMed PMID: 25493642; PubMed Central PMCID: PMC4262417.

                  Richardson-Harman N, Hendrix CW, Bumpus NN, Mauck C, Cranston RD, Yang K, Elliott J, Tanner K, McGowan I, Kashuba A, Anton PA. Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study. PloS one. 2014;9(10):e111507. PubMed PMID: 25350130; PubMed Central PMCID: PMC4211741.

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                  Vu JP, Million M, Larauche M, Luong L, Norris J, Waschek JA, Pothoulakis C, Pisegna JR, Germano PM. Inhibition of vasoactive intestinal polypeptide (VIP) induces resistance to dextran sodium sulfate (DSS)-induced colitis in mice. Journal of molecular neuroscience : MN. 2014 January;52(1):37-47. PubMed PMID: 24395090; PubMed Central PMCID: PMC4114158.

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                  Ke B, Shen XD, Zhang Y, Ji H, Gao F, Yue S, Kamo N, Zhai Y, Yamamoto M, Busuttil RW, Kupiec-Weglinski JW. KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants. Journal of hepatology. 2013 December;59(6):1200-7. PubMed PMID: 23867319; PubMed Central PMCID: PMC4524560.

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                  Sinnett-Smith J, Kisfalvi K, Kui R, Rozengurt E. Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK. Biochemical and biophysical research communications. 2013 January 4;430(1):352-7. PubMed PMID: 23159620; PubMed Central PMCID: PMC3545113.

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                  Harikumar KB, Kunnumakkara AB, Ochi N, Tong Z, Deorukhkar A, Sung B, Kelland L, Jamieson S, Sutherland R, Raynham T, Charles M, Bagherzadeh A, Foxton C, Boakes A, Farooq M, Maru D, Diagaradjane P, Matsuo Y, Sinnett-Smith J, Gelovani J, Krishnan S, Aggarwal BB, Rozengurt E, Ireson CR, Guha S. A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo. Molecular cancer therapeutics. 2010 May;9(5):1136-46. PubMed PMID: 20442301; PubMed Central PMCID: PMC2905628.

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                  Rozengurt E, Sinnett-Smith J, Kisfalvi K. Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2010 May 1;16(9):2505-11. PubMed PMID: 20388847; PubMed Central PMCID: PMC2862089.

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                  Jiang X, Sinnett-Smith J, Rozengurt E. Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. Biochemical and biophysical research communications. 2009 September 25;387(3):521-4. PubMed PMID: 19615971; PubMed Central PMCID: PMC2754135.

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                  Spiegel BM, Farid M, van Oijen MG, Laine L, Howden CW, Esrailian E. Adherence to best practice guidelines in dyspepsia: a survey comparing dyspepsia experts, community gastroenterologists and primary-care providers. Alimentary pharmacology & therapeutics. 2009 April 15;29(8):871-81. PubMed PMID: 19183152; PubMed Central PMCID: PMC2953468.

                  Desai AA, Bolus R, Nissenson A, Chertow GM, Bolus S, Solomon MD, Khawar OS, Talley J, Spiegel BM. Is there "cherry picking" in the ESRD Program? Perceptions from a Dialysis Provider Survey. Clinical journal of the American Society of Nephrology : CJASN. 2009 April;4(4):772-7. PubMed PMID: 19339407; PubMed Central PMCID: PMC2666440.

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                  Padua D, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih D, Iliopoulos D, Pothoulakis C. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. American journal of physiology. Gastrointestinal and liver physiology. 2016 September 1;311(3):G446-57. PubMed PMID: 27492330; PubMed Central PMCID: PMC5076004.

                  Wang J, Sinnett-Smith J, Stevens JV, Young SH, Rozengurt E. Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD). The Journal of biological chemistry. 2016 August 19;291(34):17988-8005. PubMed PMID: 27369082; PubMed Central PMCID: PMC5016186.

                  Park SH, Videlock EJ, Shih W, Presson AP, Mayer EA, Chang L. Adverse childhood experiences are associated with irritable bowel syndrome and gastrointestinal symptom severity. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 August;28(8):1252-60. PubMed PMID: 27061107; PubMed Central PMCID: PMC4956522.

                  Antonios JP, Soto H, Everson RG, Orpilla J, Moughon D, Shin N, Sedighim S, Yong WH, Li G, Cloughesy TF, Liau LM, Prins RM. PD-1 blockade enhances the vaccination-induced immune response in glioma. JCI insight. 2016 July 7;1(10). PubMed PMID: 27453950; PubMed Central PMCID: PMC4951098.

                  Khalil HA, Lei NY, Brinkley G, Scott A, Wang J, Kar UK, Jabaji ZB, Lewis M, Martín MG, Dunn JC, Stelzner MG. A novel culture system for adult porcine intestinal crypts. Cell and tissue research. 2016 July;365(1):123-34. PubMed PMID: 26928041; PubMed Central PMCID: PMC4919165.

                  Videlock EJ, Shih W, Adeyemo M, Mahurkar-Joshi S, Presson AP, Polytarchou C, Alberto M, Iliopoulos D, Mayer EA, Chang L. The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression. Psychoneuroendocrinology. 2016 July;69:67-76. PubMed PMID: 27038676; PubMed Central PMCID: PMC4977028.

                  Kaji I, Akiba Y, Konno K, Watanabe M, Kimura S, Iwanaga T, Kuri A, Iwamoto K, Kuwahara A, Kaunitz JD. Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon. The Journal of physiology. 2016 June 15;594(12):3339-52. PubMed PMID: 26854275; PubMed Central PMCID: PMC4908031.

                  Holschneider DP, Guo Y, Mayer EA, Wang Z. Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats. Neurobiology of stress. 2016 June 1;3:8-22. PubMed PMID: 26751119; PubMed Central PMCID: PMC4700548.

                  Padua D, Vu JP, Germano PM, Pisegna JR. The Role of Neuropeptides in Mouse Models of Colitis. Journal of molecular neuroscience : MN. 2016 June;59(2):203-10. PubMed PMID: 26646243; PubMed Central PMCID: PMC4884658.

                  Scott A, Rouch JD, Jabaji Z, Khalil HA, Solorzano S, Lewis M, Martín MG, Stelzner MG, Dunn JC. Long-term renewable human intestinal epithelial stem cells as monolayers: A potential for clinical use. Journal of pediatric surgery. 2016 June;51(6):995-1000. PubMed PMID: 26995514; PubMed Central PMCID: PMC4921284.

                  Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. 2016 June;159(6):1520-1527. PubMed PMID: 26847803; PubMed Central PMCID: PMC4856542.

                  Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. American journal of physiology. Gastrointestinal and liver physiology. 2016 June 1;310(11):G1124-37. PubMed PMID: 27151939; PubMed Central PMCID: PMC5005285.

                  Yu J, Liu SH, Sanchez R, Nemunaitis J, Rozengurt E, Brunicardi FC. PDX1 associated therapy in translational medicine. Annals of translational medicine. 2016 June;4(11):214. PubMed PMID: 27386488; PubMed Central PMCID: PMC4916355.

                  Bakirtzi K, Law IK, Xue X, Iliopoulos D, Shah YM, Pothoulakis C. Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling. Journal of immunology (Baltimore, Md. : 1950). 2016 May 15;196(10):4311-21. PubMed PMID: 27076683; PubMed Central PMCID: PMC4868643.

                  Deriu E, Boxx GM, He X, Pan C, Benavidez SD, Cen L, Rozengurt N, Shi W, Cheng G. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS pathogens. 2016 May;12(5):e1005572. PubMed PMID: 27149619; PubMed Central PMCID: PMC4858270.

                  Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Molecular cancer research : MCR. 2016 May;14(5):437-47. PubMed PMID: 26979711; PubMed Central PMCID: PMC4867256.

                  Vorvis C, Koutsioumpa M, Iliopoulos D. Developments in miRNA gene signaling pathways in pancreatic cancer. Future oncology (London, England). 2016 May;12(9):1135-50. PubMed PMID: 26984178; PubMed Central PMCID: PMC5551925.

                  Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Science translational medicine. 2016 April 13;8(334):334ra54. PubMed PMID: 27075628; PubMed Central PMCID: PMC4934679.

                  Ackerman AL, Jellison FC, Lee UJ, Bradesi S, Rodríguez LV. The Glt1 glutamate receptor mediates the establishment and perpetuation of chronic visceral pain in an animal model of stress-induced bladder hyperalgesia. American journal of physiology. Renal physiology. 2016 April 1;310(7):F628-F636. PubMed PMID: 26697981; PubMed Central PMCID: PMC5504462.

                  Gupta A, Labus J, Kilpatrick LA, Bonyadi M, Ashe-McNalley C, Heendeniya N, Bradesi S, Chang L, Mayer EA. Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females. Brain structure & function. 2016 April;221(3):1667-79. PubMed PMID: 25630611; PubMed Central PMCID: PMC4573367.

                  Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly. International journal of antimicrobial agents. 2016 April;47(4):289-96. PubMed PMID: 27013001; PubMed Central PMCID: PMC4833571.

                  Wang J, Han L, Sinnett-Smith J, Han LL, Stevens JV, Rozengurt N, Young SH, Rozengurt E. Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552. American journal of physiology. Cell physiology. 2016 April 1;310(7):C542-57. PubMed PMID: 26739494; PubMed Central PMCID: PMC4824155.

                  Yuan PQ, Wu SV, Pothoulakis C, Taché Y. Urocortins and CRF receptor type 2 variants in the male rat colon: gene expression and regulation by endotoxin and anti-inflammatory effect. American journal of physiology. Gastrointestinal and liver physiology. 2016 March 15;310(6):G387-98. PubMed PMID: 26744472; PubMed Central PMCID: PMC4796293.

                  Hertzer KM, Xu M, Moro A, Dawson DW, Du L, Li G, Chang HH, Stark AP, Jung X, Hines OJ, Eibl G. Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer. Pancreas. 2016 March;45(3):458-65. PubMed PMID: 26495779; PubMed Central PMCID: PMC4854638.

                  Mahurkar S, Polytarchou C, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 March;28(3):410-22. PubMed PMID: 26670691; PubMed Central PMCID: PMC4760882.

                  Law IK, Jensen D, Bunnett NW, Pothoulakis C. Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin. Scientific reports. 2016 February 23;6:22195. PubMed PMID: 26902265; PubMed Central PMCID: PMC4763298.

                  Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi K, Dulai GS, Machicado GA. Natural history of definitive diverticular hemorrhage based on stigmata of recent hemorrhage and colonoscopic Doppler blood flow monitoring for risk stratification and definitive hemostasis. Gastrointestinal endoscopy. 2016 February;83(2):416-23. PubMed PMID: 26227931; PubMed Central PMCID: PMC4715947.

                  Walwyn WM, Chen W, Kim H, Minasyan A, Ennes HS, McRoberts JA, Marvizón JC. Sustained Suppression of Hyperalgesia during Latent Sensitization by μ-, δ-, and κ-opioid receptors and α2A Adrenergic Receptors: Role of Constitutive Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2016 January 6;36(1):204-21. PubMed PMID: 26740662; PubMed Central PMCID: PMC4701961.

                  Birtolo C, Go VL, Ptasznik A, Eibl G, Pandol SJ. Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas. 2016 January;45(1):21-31. PubMed PMID: 26658038; PubMed Central PMCID: PMC4859755.

                  Camus M, Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi KA, Machicado GA, Dulai GS, Jensen ME, Gornbein JA. Comparison of Three Risk Scores to Predict Outcomes of Severe Lower Gastrointestinal Bleeding. Journal of clinical gastroenterology. 2016 January;50(1):52-8. PubMed PMID: 25599218; PubMed Central PMCID: PMC4504830.

                  Hoffman JM, Baritaki S, Ruiz JJ, Sideri A, Pothoulakis C. Corticotropin-Releasing Hormone Receptor 2 Signaling Promotes Mucosal Repair Responses after Colitis. The American journal of pathology. 2016 January;186(1):134-44. PubMed PMID: 26597886; PubMed Central PMCID: PMC4714033.

                  Hong JY, Naliboff B, Labus JS, Gupta A, Kilpatrick LA, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Mayer EA. Altered brain responses in subjects with irritable bowel syndrome during cued and uncued pain expectation. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 January;28(1):127-38. PubMed PMID: 26526698; PubMed Central PMCID: PMC4943658.

                  Jarcho JM, Feier NA, Labus JS, Naliboff B, Smith SR, Hong JY, Colloca L, Tillisch K, Mandelkern MA, Mayer EA, London ED. Placebo analgesia: Self-report measures and preliminary evidence of cortical dopamine release associated with placebo response. NeuroImage. Clinical. 2016;10:107-14. PubMed PMID: 26759785; PubMed Central PMCID: PMC4683423.

                  Jensen DM, Ohning GV, Kovacs TO, Ghassemi KA, Jutabha R, Dulai GS, Machicado GA. Doppler endoscopic probe as a guide to risk stratification and definitive hemostasis of peptic ulcer bleeding. Gastrointestinal endoscopy. 2016 January;83(1):129-36. PubMed PMID: 26318834; PubMed Central PMCID: PMC4691549.

                  Labus JS, Naliboff B, Kilpatrick L, Liu C, Ashe-McNalley C, dos Santos IR, Alaverdyan M, Woodworth D, Gupta A, Ellingson BM, Tillisch K, Mayer EA. Pain and Interoception Imaging Network (PAIN): A multimodal, multisite, brain-imaging repository for chronic somatic and visceral pain disorders. NeuroImage. 2016 January 1;124(Pt B):1232-7. PubMed PMID: 25902408; PubMed Central PMCID: PMC4627849.

                  Latorre R, Huynh J, Mazzoni M, Gupta A, Bonora E, Clavenzani P, Chang L, Mayer EA, De Giorgio R, Sternini C. Expression of the Bitter Taste Receptor, T2R38, in Enteroendocrine Cells of the Colonic Mucosa of Overweight/Obese vs. Lean Subjects. PloS one. 2016;11(2):e0147468. PubMed PMID: 26866366; PubMed Central PMCID: PMC4750998.

                  Moussaoui N, Larauche M, Biraud M, Molet J, Million M, Mayer E, Taché Y. Limited Nesting Stress Alters Maternal Behavior and In Vivo Intestinal Permeability in Male Wistar Pup Rats. PloS one. 2016;11(5):e0155037. PubMed PMID: 27149676; PubMed Central PMCID: PMC4858303.

                  Rouch JD, Scott A, Lei NY, Solorzano-Vargas RS, Wang J, Hanson EM, Kobayashi M, Lewis M, Stelzner MG, Dunn JC, Eckmann L, Martín MG. Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. PloS one. 2016;11(1):e0148216. PubMed PMID: 26820624; PubMed Central PMCID: PMC4731053.

                  Zhou G, Yu J, Wang A, Liu SH, Sinnett-Smith J, Wu J, Sanchez R, Nemunaitis J, Ricordi C, Rozengurt E, Brunicardi FC. Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma. Current molecular medicine. 2016;16(1):83-90. PubMed PMID: 26695692; PubMed Central PMCID: PMC4994969.

                  Vuong HE, Hardi CN, Barnes S, Brecha NC. Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 December 2;35(48):15955-70. PubMed PMID: 26631476; PubMed Central PMCID: PMC4666919.

                  Kilpatrick LA, Istrin JJ, Gupta A, Naliboff BD, Tillisch K, Labus JS, Mayer EA. Sex commonalities and differences in the relationship between resilient personality and the intrinsic connectivity of the salience and default mode networks. Biological psychology. 2015 December;112:107-15. PubMed PMID: 26440126; PubMed Central PMCID: PMC5012423.

                  Phan J, Benhammou JN, Pisegna JR. Gastric Hypersecretory States: Investigation and Management. Current treatment options in gastroenterology. 2015 December;13(4):386-97. PubMed PMID: 26342486; PubMed Central PMCID: PMC4633316.

                  Stark AP, Chang HH, Jung X, Moro A, Hertzer K, Xu M, Schmidt A, Hines OJ, Eibl G. E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice. Surgery. 2015 December;158(6):1564-72. PubMed PMID: 26297056; PubMed Central PMCID: PMC4637247.

                  Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of experimental medicine. 2015 November 16;212(12):2147-63. PubMed PMID: 26552708; PubMed Central PMCID: PMC4647265.

                  Chang HH, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G. Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1. American journal of physiology. Cell physiology. 2015 November 15;309(10):C639-49. PubMed PMID: 26310818; PubMed Central PMCID: PMC4652080.

                  Vu JP, Goyal D, Luong L, Oh S, Sandhu R, Norris J, Parsons W, Pisegna JR, Germano PM. PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin. American journal of physiology. Gastrointestinal and liver physiology. 2015 November 15;309(10):G816-25. PubMed PMID: 26336928; PubMed Central PMCID: PMC4652141.

                  Young SH, Rey O, Rozengurt E. Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: Impact of the highly conservative mutation Ser170Thr. Biochemical and biophysical research communications. 2015 November 6;467(1):1-6. PubMed PMID: 26431875; PubMed Central PMCID: PMC4613767.

                  Rodriguez JA, Huerta-Yepez S, Law IK, Baay-Guzman GJ, Tirado-Rodriguez B, Hoffman JM, Iliopoulos D, Hommes DW, Verspaget HW, Chang L, Pothoulakis C, Baritaki S. Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling. Cellular and molecular gastroenterology and hepatology. 2015 November 1;1(6):610-630. PubMed PMID: 26495412; PubMed Central PMCID: PMC4610032.

                  Vuong HE, Pérez de Sevilla Müller L, Hardi CN, McMahon DG, Brecha NC. Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines. Neuroscience. 2015 October 29;307:319-37. PubMed PMID: 26335381; PubMed Central PMCID: PMC4603663.

                  Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D. MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice. Gastroenterology. 2015 October;149(4):981-92.e11. PubMed PMID: 26055138; PubMed Central PMCID: PMC4584179.

                  Fang K, Sideri A, Law IK, Bakirtzi K, Polytarchou C, Iliopoulos D, Pothoulakis C. Identification of a novel substance P (SP)-neurokinin-1 receptor (NK-1R) microRNA-221-5p inflammatory network in human colonic epithelial cells. Cellular and molecular gastroenterology and hepatology. 2015 September 1;1(5):503-515. PubMed PMID: 26645045; PubMed Central PMCID: PMC4669978.

                  Hubbard CS, Hong J, Jiang Z, Ebrat B, Suyenobu B, Smith S, Heendeniya N, Naliboff BD, Tillisch K, Mayer EA, Labus JS. Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 September;27(9):1282-94. PubMed PMID: 26087779; PubMed Central PMCID: PMC4550526.

                  Cherukuri DP, Deignan JL, Das K, Grody WW, Herschman H. Instability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma. Molecular oncology. 2015 August;9(7):1252-8. PubMed PMID: 25817443; PubMed Central PMCID: PMC4523444.

                  Irimia A, Labus JS, Torgerson CM, Van Horn JD, Mayer EA. Altered viscerotopic cortical innervation in patients with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 August;27(8):1075-81. PubMed PMID: 25952540; PubMed Central PMCID: PMC4520752.

                  Kaunitz JD. The Discovery of PCR: ProCuRement of Divine Power. Digestive diseases and sciences. 2015 August;60(8):2230-1. PubMed PMID: 26077976; PubMed Central PMCID: PMC4501591.

                  Kobayashi M, Lei NY, Wang Q, Wu BM, Dunn JC. Orthogonally oriented scaffolds with aligned fibers for engineering intestinal smooth muscle. Biomaterials. 2015 August;61:75-84. PubMed PMID: 26001072; PubMed Central PMCID: PMC4464968.

                  Labus JS, Van Horn JD, Gupta A, Alaverdyan M, Torgerson C, Ashe-McNalley C, Irimia A, Hong JY, Naliboff B, Tillisch K, Mayer EA. Multivariate morphological brain signatures predict patients with chronic abdominal pain from healthy control subjects. Pain. 2015 August;156(8):1545-54. PubMed PMID: 25906347; PubMed Central PMCID: PMC4504800.

                  O'Mahony F, Wroblewski K, O'Byrne SM, Jiang H, Clerkin K, Benhammou J, Blaner WS, Beaven SW. Liver X receptors balance lipid stores in hepatic stellate cells through Rab18, a retinoid responsive lipid droplet protein. Hepatology (Baltimore, Md.). 2015 August;62(2):615-26. PubMed PMID: 25482505; PubMed Central PMCID: PMC4458237.

                  Tuominen I, Beaven SW. Intestinal farnesoid X receptor puts a fresh coat of wax on fatty liver. Hepatology (Baltimore, Md.). 2015 August;62(2):646-8. PubMed PMID: 25998695; PubMed Central PMCID: PMC4523235.

                  Law IK, Bakirtzi K, Polytarchou C, Oikonomopoulos A, Hommes D, Iliopoulos D, Pothoulakis C. Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis. Gut. 2015 July;64(7):1095-104. PubMed PMID: 25112884; PubMed Central PMCID: PMC4422787.

                  Lugea A, Waldron RT, Pandol SJ. Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2015 July;15(4 Suppl):S1-5. PubMed PMID: 25736240; PubMed Central PMCID: PMC4515411.

                  Stengel A, Karasawa H, Taché Y. The role of brain somatostatin receptor 2 in the regulation of feeding and drinking behavior. Hormones and behavior. 2015 July;73:15-22. PubMed PMID: 26026616; PubMed Central PMCID: PMC4546908.

                  Sanmiguel C, Gupta A, Mayer EA. Gut Microbiome and Obesity: A Plausible Explanation for Obesity. Current obesity reports. 2015 June;4(2):250-61. PubMed PMID: 26029487; PubMed Central PMCID: PMC4443745.

                  Vu JP, Larauche M, Flores M, Luong L, Norris J, Oh S, Liang LJ, Waschek J, Pisegna JR, Germano PM. Regulation of Appetite, Body Composition, and Metabolic Hormones by Vasoactive Intestinal Polypeptide (VIP). Journal of molecular neuroscience : MN. 2015 June;56(2):377-87. PubMed PMID: 25904310; PubMed Central PMCID: PMC4458420.

                  Gupta A, Rapkin AJ, Gill Z, Kilpatrick L, Fling C, Stains J, Masghati S, Tillisch K, Mayer EA, Labus JS. Disease-related differences in resting-state networks: a comparison between localized provoked vulvodynia, irritable bowel syndrome, and healthy control subjects. Pain. 2015 May;156(5):809-19. PubMed PMID: 25735001; PubMed Central PMCID: PMC4402252.

                  Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D. A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. Inflammatory bowel diseases. 2015 May;21(5):996-1005. PubMed PMID: 25738378; PubMed Central PMCID: PMC4402238.

                  Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JC, Martin MG, Lagasse E, Zhang L, Yu J. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Scientific reports. 2015 April 10;5:8566. PubMed PMID: 25858503; PubMed Central PMCID: PMC4392360.

                  Wu JX, Liu SH, Nemunaitis JJ, Brunicardi FC. Liposomal insulin promoter-thymidine kinase gene therapy followed by ganciclovir effectively ablates human pancreatic cancer in mice. Cancer letters. 2015 April 10;359(2):206-10. PubMed PMID: 25596375; PubMed Central PMCID: PMC4336837.

                  Akiba Y, Kaunitz JD, Million M. Peripheral corticotropin-releasing factor receptor type 2 activation increases colonic blood flow through nitric oxide pathway in rats. Digestive diseases and sciences. 2015 April;60(4):858-67. PubMed PMID: 25701320; PubMed Central PMCID: PMC4501405.

                  Anselmi L, Huynh J, Duraffourd C, Jaramillo I, Vegezzi G, Saccani F, Boschetti E, Brecha NC, De Giorgio R, Sternini C. Activation of μ opioid receptors modulates inflammation in acute experimental colitis. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 April;27(4):509-23. PubMed PMID: 25690069; PubMed Central PMCID: PMC4405133.

                  Liu Z, Sun F, Braun J, McGovern DP, Piantadosi S. Multilevel regularized regression for simultaneous taxa selection and network construction with metagenomic count data. Bioinformatics (Oxford, England). 2015 April 1;31(7):1067-74. PubMed PMID: 25416747; PubMed Central PMCID: PMC4382903.

                  Marvizon JC, Walwyn W, Minasyan A, Chen W, Taylor BK. Latent sensitization: a model for stress-sensitive chronic pain. Current protocols in neuroscience. 2015 April 1;71:9.50.1-14. PubMed PMID: 25829356; PubMed Central PMCID: PMC4532319.

                  Mayer EA, Gupta A, Kilpatrick LA, Hong JY. Imaging brain mechanisms in chronic visceral pain. Pain. 2015 April;156 Suppl 1:S50-63. PubMed PMID: 25789437; PubMed Central PMCID: PMC4428597.

                  Sideri A, Stavrakis D, Bowe C, Shih DQ, Fleshner P, Arsenescu V, Arsenescu R, Turner JR, Pothoulakis C, Karagiannides I. Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1. American journal of physiology. Gastrointestinal and liver physiology. 2015 April 1;308(7):G591-604. PubMed PMID: 25591865; PubMed Central PMCID: PMC4385897.

                  Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2. Molecular cancer therapeutics. 2015 April;14(4):1014-23. PubMed PMID: 25673820; PubMed Central PMCID: PMC4394038.

                  Tarling EJ, Ahn H, de Aguiar Vallim TQ. The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2. Arteriosclerosis, thrombosis, and vascular biology. 2015 April;35(4):787-95. PubMed PMID: 25593129; PubMed Central PMCID: PMC4376635.

                  Gukovsky I, Gukovskaya AS. Impaired autophagy triggers chronic pancreatitis: lessons from pancreas-specific atg5 knockout mice. Gastroenterology. 2015 March;148(3):501-5. PubMed PMID: 25613315; PubMed Central PMCID: PMC4443443.

                  Liu Y, Ji H, Zhang Y, Shen X, Gao F, He X, Li GA, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury. Journal of hepatology. 2015 March;62(3):563-72. PubMed PMID: 25450716; PubMed Central PMCID: PMC4336640.

                  Sakanaka T, Inoue T, Yorifuji N, Iguchi M, Fujiwara K, Narabayashi K, Kakimoto K, Nouda S, Okada T, Kuramoto T, Ishida K, Abe Y, Takeuchi T, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. The effects of a TGR5 agonist and a dipeptidyl peptidase IV inhibitor on dextran sulfate sodium-induced colitis in mice. Journal of gastroenterology and hepatology. 2015 March;30 Suppl 1:60-5. PubMed PMID: 25827806; PubMed Central PMCID: PMC4874188.

                  Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. The Journal of biological chemistry. 2015 February 27;290(9):5566-81. PubMed PMID: 25468909; PubMed Central PMCID: PMC4342471.

                  Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. Septin dynamics are essential for exocytosis. The Journal of biological chemistry. 2015 February 27;290(9):5280-97. PubMed PMID: 25575596; PubMed Central PMCID: PMC4342448.

                  Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell metabolism. 2015 February 3;21(2):334-46. PubMed PMID: 25651185; PubMed Central PMCID: PMC4349439.

                  de Aguiar Vallim TQ, Tarling EJ, Ahn H, Hagey LR, Romanoski CE, Lee RG, Graham MJ, Motohashi H, Yamamoto M, Edwards PA. MAFG is a transcriptional repressor of bile acid synthesis and metabolism. Cell metabolism. 2015 February 3;21(2):298-310. PubMed PMID: 25651182; PubMed Central PMCID: PMC4317590.

                  Bromley EG, May FP, Federer L, Spiegel BM, van Oijen MG. Explaining persistent under-use of colonoscopic cancer screening in African Americans: a systematic review. Preventive medicine. 2015 February;71:40-8. PubMed PMID: 25481094; PubMed Central PMCID: PMC4329030.

                  Kaji I, Iwanaga T, Watanabe M, Guth PH, Engel E, Kaunitz JD, Akiba Y. SCFA transport in rat duodenum. American journal of physiology. Gastrointestinal and liver physiology. 2015 February 1;308(3):G188-97. PubMed PMID: 25394661; PubMed Central PMCID: PMC4312951.

                  Nguyen AH, Toste PA, Farrell JJ, Clerkin BM, Williams J, Muthusamy VR, Watson RR, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Current recommendations for surveillance and surgery of intraductal papillary mucinous neoplasms may overlook some patients with cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2015 February;19(2):258-65. PubMed PMID: 25373706; PubMed Central PMCID: PMC4305480.

                  Tan YV, Abad C, Wang Y, Lopez R, Waschek J. VPAC2 (vasoactive intestinal peptide receptor type 2) receptor deficient mice develop exacerbated experimental autoimmune encephalomyelitis with increased Th1/Th17 and reduced Th2/Treg responses. Brain, behavior, and immunity. 2015 February;44:167-175. PubMed PMID: 25305591; PubMed Central PMCID: PMC4275378.

                  Taché Y, Million M. Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia. Journal of neurogastroenterology and motility. 2015 January 31;21(1):8-24. PubMed PMID: 25611064; PubMed Central PMCID: PMC4288101.

                  Coveleskie K, Gupta A, Kilpatrick LA, Mayer ED, Ashe-McNalley C, Stains J, Labus JS, Mayer EA. Altered functional connectivity within the central reward network in overweight and obese women. Nutrition & diabetes. 2015 January 19;5:e148. PubMed PMID: 25599560; PubMed Central PMCID: PMC4314578.

                  Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology. 2015 January 15;475:46-55. PubMed PMID: 25462345; PubMed Central PMCID: PMC4284078.

                  Abad C, Cheung-Lau G, Coûté-Monvoisin AC, Waschek JA. Vasoactive intestinal peptide-deficient mice exhibit reduced pathology in trinitrobenzene sulfonic acid-induced colitis. Neuroimmunomodulation. 2015;22(3):203-12. PubMed PMID: 25301381; PubMed Central PMCID: PMC4297532.

                  Bradesi S, Karagiannides I, Bakirtzi K, Joshi SM, Koukos G, Iliopoulos D, Pothoulakis C, Mayer EA. Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat. PloS one. 2015;10(7):e0130938. PubMed PMID: 26222740; PubMed Central PMCID: PMC4519289.

                  Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. Journal of Alzheimer's disease : JAD. 2015;43(3):967-76. PubMed PMID: 25125464; PubMed Central PMCID: PMC4258165.

                  Chen R, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM, Maitra A, Brentnall TA. Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. Laboratory investigation; a journal of technical methods and pathology. 2015 January;95(1):43-55. PubMed PMID: 25347153; PubMed Central PMCID: PMC4281293.

                  Cheng M, Ho S, Yoo JH, Tran DH, Bakirtzi K, Su B, Tran DH, Kubota Y, Ichikawa R, Koon HW. Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts. Clinical and experimental gastroenterology. 2015;8:13-29. PubMed PMID: 25565877; PubMed Central PMCID: PMC4274046.

                  Gupta A, Mayer EA, Sanmiguel CP, Van Horn JD, Woodworth D, Ellingson BM, Fling C, Love A, Tillisch K, Labus JS. Patterns of brain structural connectivity differentiate normal weight from overweight subjects. NeuroImage. Clinical. 2015;7:506-17. PubMed PMID: 25737959; PubMed Central PMCID: PMC4338207.

                  Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 January 1;21(1):157-65. PubMed PMID: 25348515; PubMed Central PMCID: PMC4286535.

                  Khalil HA, Lei NY, Nie W, Lewis MS, Stelzner MG, Martín MG, Dunn JC, Yoo J. Primary Myofibroblasts Maintain Short-Term Viability following Submucosal Injection in Syngeneic, Immune-Competent Mice Utilizing Murine Colonoscopy. PloS one. 2015;10(5):e0127258. PubMed PMID: 26016485; PubMed Central PMCID: PMC4445916.

                  Kutch JJ, Yani MS, Asavasopon S, Kirages DJ, Rana M, Cosand L, Labus JS, Kilpatrick LA, Ashe-McNalley C, Farmer MA, Johnson KA, Ness TJ, Deutsch G, Harris RE, Apkarian AV, Clauw DJ, Mackey SC, Mullins C, Mayer EA. Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study. NeuroImage. Clinical. 2015;8:493-502. PubMed PMID: 26106574; PubMed Central PMCID: PMC4474411.

                  Law IK, Pothoulakis C. MicroRNA-133α regulates neurotensin-associated colonic inflammation in colonic epithelial cells and experimental colitis. RNA & disease (Houston, Tex.). 2015;2(1). PubMed PMID: 26005712; PubMed Central PMCID: PMC4441413.

                  Li Y, Go VL, Sarkar FH. The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome. Pancreas. 2015 January;44(1):1-10. PubMed PMID: 25493373; PubMed Central PMCID: PMC4264839.

                  Martinez L, Ermolova NV, Ishikawa TO, Stout DB, Herschman HR, Spencer MJ. A reporter mouse for optical imaging of inflammation in mdx muscles. Skeletal muscle. 2015;5:15. PubMed PMID: 25949789; PubMed Central PMCID: PMC4422315.

                  Marzagalli R, Scuderi S, Drago F, Waschek JA, Castorina A. Emerging Role of PACAP as a New Potential Therapeutic Target in Major Diabetes Complications. International journal of endocrinology. 2015;2015:160928. PubMed PMID: 26074958; PubMed Central PMCID: PMC4446501.

                  McGowan I, Anton PA, Elliott J, Cranston RD, Duffill K, Althouse AD, Hawkins KL, De Rosa SC. Exploring the feasibility of multi-site flow cytometric processing of gut associated lymphoid tissue with centralized data analysis for multi-site clinical trials. PloS one. 2015;10(5):e0126454. PubMed PMID: 26010577; PubMed Central PMCID: PMC4444258.

                  Mulak A, Larauche M, Biraud M, Million M, Rivier J, Taché Y. Selective agonists of somatostatin receptor subtype 1 or 2 injected peripherally induce antihyperalgesic effect in two models of visceral hypersensitivity in mice. Peptides. 2015 January;63:71-80. PubMed PMID: 25451334; PubMed Central PMCID: PMC4385413.

                  Orand A, Gupta A, Shih W, Presson AP, Hammer C, Niesler B, Heendeniya N, Mayer EA, Chang L. Catecholaminergic Gene Polymorphisms Are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome. PloS one. 2015;10(8):e0135910. PubMed PMID: 26288143; PubMed Central PMCID: PMC4546052.

                  Taché Y. Corticotrophin-releasing factor 1 activation in the central amygdale and visceral hyperalgesia. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 January;27(1):1-6. PubMed PMID: 25557223; PubMed Central PMCID: PMC4389773.

                  Wang L, Mogami S, Yakabi S, Karasawa H, Yamada C, Yakabi K, Hattori T, Taché Y. Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito. PloS one. 2015;10(9):e0139325. PubMed PMID: 26421719; PubMed Central PMCID: PMC4589401.

                  Wang Y, Yan C, Liu L, Wang W, Du H, Fan W, Lutfy K, Jiang M, Friedman TC, Liu Y. 11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue. American journal of physiology. Endocrinology and metabolism. 2015 January 1;308(1):E84-95. PubMed PMID: 25389364; PubMed Central PMCID: PMC4281684.

                  Yoo JH, Ho S, Tran DH, Cheng M, Bakirtzi K, Kukota Y, Ichikawa R, Su B, Tran DH, Hing TC, Chang I, Shih DQ, Issacson RE, Gallo RL, Fiocchi C, Pothoulakis C, Koon HW. Anti-fibrogenic effects of the anti-microbial peptide cathelicidin in murine colitis-associated fibrosis. Cellular and molecular gastroenterology and hepatology. 2015 January;1(1):55-74.e1. PubMed PMID: 25729764; PubMed Central PMCID: PMC4338438.

                  Zhu J, Lu T, Yue S, Shen X, Gao F, Busuttil RW, Kupiec-Weglinski JW, Xia Q, Zhai Y. Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation. Transplantation. 2015 January;99(1):48-55. PubMed PMID: 25340604; PubMed Central PMCID: PMC4272660.

                  Akiba Y, Kaunitz JD. Prostaglandin pathways in duodenal chemosensing. Journal of gastroenterology and hepatology. 2014 December;29 Suppl 4:93-8. PubMed PMID: 25521740; PubMed Central PMCID: PMC4451058.

                  Bagarinao E, Johnson KA, Martucci KT, Ichesco E, Farmer MA, Labus J, Ness TJ, Harris R, Deutsch G, Apkarian AV, Mayer EA, Clauw DJ, Mackey S. Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network study. Pain. 2014 December;155(12):2502-9. PubMed PMID: 25242566; PubMed Central PMCID: PMC4504202.

                  Buzzanco A, Gomez A, Rodriguez E, French BA, Tillman BA, Chang S, Ganapathy E, Junrungsee S, Zarrinpar A, Agopian VG, Naini BV, French SW Jr, French SW Sr. Digital quantitation of HCC-associated stem cell markers and protein quality control factors using tissue arrays of human liver sections. Experimental and molecular pathology. 2014 December;97(3):399-410. PubMed PMID: 25218810; PubMed Central PMCID: PMC4262606.

                  Donahue TR, Nguyen AH, Moughan J, Li L, Tatishchev S, Toste P, Farrell JJ. Stromal microRNA-21 levels predict response to 5-fluorouracil in patients with pancreatic cancer. Journal of surgical oncology. 2014 December;110(8):952-9. PubMed PMID: 25132574; PubMed Central PMCID: PMC4232442.

                  Ji H, Liu Y, Zhang Y, Shen XD, Gao F, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. T-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury. Hepatology (Baltimore, Md.). 2014 December;60(6):2052-2064. PubMed PMID: 25066922; PubMed Central PMCID: PMC4396987.

                  Karasawa H, Pietra C, Giuliano C, Garcia-Rubio S, Xu X, Yakabi S, Taché Y, Wang L. New ghrelin agonist, HM01 alleviates constipation and L-dopa-delayed gastric emptying in 6-hydroxydopamine rat model of Parkinson's disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 December;26(12):1771-82. PubMed PMID: 25327342; PubMed Central PMCID: PMC4457321.

                  Stengel A, Taché Y. Brain peptides and the modulation of postoperative gastric ileus. Current opinion in pharmacology. 2014 December;19:31-7. PubMed PMID: 24999843; PubMed Central PMCID: PMC4254047.

                  Wagner JP, Sullins VF, Dunn JC. Skin-derived precursors generate enteric-type neurons in aganglionic jejunum. Journal of pediatric surgery. 2014 December;49(12):1809-14. PubMed PMID: 25487489; PubMed Central PMCID: PMC4261145.

                  Wagner JP, Sullins VF, Khalil HA, Dunn JC. A durable model of Hirschsprung's colon. Journal of pediatric surgery. 2014 December;49(12):1804-8. PubMed PMID: 25487488; PubMed Central PMCID: PMC4261142.

                  Hong C, Marshall SM, McDaniel AL, Graham M, Layne JD, Cai L, Scotti E, Boyadjian R, Kim J, Chamberlain BT, Tangirala RK, Jung ME, Fong L, Lee R, Young SG, Temel RE, Tontonoz P. The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice. Cell metabolism. 2014 November 4;20(5):910-8. PubMed PMID: 25440061; PubMed Central PMCID: PMC4261644.

                  Tong M, Jacobs JP, McHardy IH, Braun J. Sampling of intestinal microbiota and targeted amplification of bacterial 16S rRNA genes for microbial ecologic analysis. Current protocols in immunology. 2014 November 3;107:7.41.1-11. PubMed PMID: 25367129; PubMed Central PMCID: PMC4457454.

                  Balaji K, French CT, Miller JF, Colicelli J. The RAB5-GEF function of RIN1 regulates multiple steps during Listeria monocytogenes infection. Traffic (Copenhagen, Denmark). 2014 November;15(11):1206-18. PubMed PMID: 25082076; PubMed Central PMCID: PMC4282165.

                  Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR. Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. Molecular cancer research : MCR. 2014 November;12(11):1677-88. PubMed PMID: 25063587; PubMed Central PMCID: PMC4233191.

                  Rozengurt E, Soares HP, Sinnet-Smith J. Suppression of feedback loops mediated by PI3K/mTOR induces multiple overactivation of compensatory pathways: an unintended consequence leading to drug resistance. Molecular cancer therapeutics. 2014 November;13(11):2477-88. PubMed PMID: 25323681; PubMed Central PMCID: PMC4222988.

                  Shih DQ, Zheng L, Zhang X, Zhang H, Kanazawa Y, Ichikawa R, Wallace KL, Chen J, Pothoulakis C, Koon HW, Targan SR. Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis. Mucosal immunology. 2014 November;7(6):1492-503. PubMed PMID: 24850426; PubMed Central PMCID: PMC4205266.

                  Spiegel BM, Hays RD, Bolus R, Melmed GY, Chang L, Whitman C, Khanna PP, Paz SH, Hays T, Reise S, Khanna D. Development of the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) gastrointestinal symptom scales. The American journal of gastroenterology. 2014 November;109(11):1804-14. PubMed PMID: 25199473; PubMed Central PMCID: PMC4285435.

                  Hong JY, Kilpatrick LA, Labus JS, Gupta A, Katibian D, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Naliboff B, Mayer EA. Sex and disease-related alterations of anterior insula functional connectivity in chronic abdominal pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 October 22;34(43):14252-9. PubMed PMID: 25339739; PubMed Central PMCID: PMC4205551.

                  Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Molecular cancer therapeutics. 2014 October;13(10):2303-14. PubMed PMID: 25082960; PubMed Central PMCID: PMC4188417.

                  Itoh Y, Arnold AP. X chromosome regulation of autosomal gene expression in bovine blastocysts. Chromosoma. 2014 October;123(5):481-9. PubMed PMID: 24817096; PubMed Central PMCID: PMC4170013.

                  Ruegger PM, Clark RT, Weger JR, Braun J, Borneman J. Improved resolution of bacteria by high throughput sequence analysis of the rRNA internal transcribed spacer. Journal of microbiological methods. 2014 October;105:82-7. PubMed PMID: 25034229; PubMed Central PMCID: PMC4160368.

                  Arnold AP. Conceptual frameworks and mouse models for studying sex differences in physiology and disease: why compensation changes the game. Experimental neurology. 2014 September;259:2-9. PubMed PMID: 24509348; PubMed Central PMCID: PMC4125548.

                  Im E, Jung J, Pothoulakis C, Rhee SH. Disruption of Pten speeds onset and increases severity of spontaneous colitis in Il10(-/-) mice. Gastroenterology. 2014 September;147(3):667-679.e10. PubMed PMID: 24882466; PubMed Central PMCID: PMC4143453.

                  Liu Y, Yuan J, Tan T, Jia W, Lugea A, Mareninova O, Waldron RT, Pandol SJ. Genetic inhibition of protein kinase Cε attenuates necrosis in experimental pancreatitis. American journal of physiology. Gastrointestinal and liver physiology. 2014 September 1;307(5):G550-63. PubMed PMID: 25035113; PubMed Central PMCID: PMC4154116.

                  Costes S, Butler PC. Insulin-degrading enzyme inhibition, a novel therapy for type 2 diabetes?. Cell metabolism. 2014 August 5;20(2):201-3. PubMed PMID: 25100059; PubMed Central PMCID: PMC4144405.

                  Calkin AC, Lee SD, Kim J, Van Stijn CM, Wu XH, Lusis AJ, Hong C, Tangirala RI, Tontonoz P. Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in mice. Circulation research. 2014 August 1;115(4):442-9. PubMed PMID: 24935961; PubMed Central PMCID: PMC4119488.

                  Koon HW, Ho S, Hing TC, Cheng M, Chen X, Ichikawa Y, Kelly CP, Pothoulakis C. Fidaxomicin inhibits Clostridium difficile toxin A-mediated enteritis in the mouse ileum. Antimicrobial agents and chemotherapy. 2014 August;58(8):4642-50. PubMed PMID: 24890583; PubMed Central PMCID: PMC4135997.

                  Ngun TC, Ghahramani NM, Creek MM, Williams-Burris SM, Barseghyan H, Itoh Y, Sánchez FJ, McClusky R, Sinsheimer JS, Arnold AP, Vilain E. Feminized behavior and brain gene expression in a novel mouse model of Klinefelter Syndrome. Archives of sexual behavior. 2014 August;43(6):1043-57. PubMed PMID: 24923877; PubMed Central PMCID: PMC4371776.

                  Viitasalo L, Niemi L, Ashorn M, Ashorn S, Braun J, Huhtala H, Collin P, Mäki M, Kaukinen K, Kurppa K, Iltanen S. Early microbial markers of celiac disease. Journal of clinical gastroenterology. 2014 August;48(7):620-4. PubMed PMID: 24518796; PubMed Central PMCID: PMC4082475.

                  Karasawa H, Yakabi S, Wang L, Taché Y. Orexin-1 receptor mediates the increased food and water intake induced by intracerebroventricular injection of the stable somatostatin pan-agonist, ODT8-SST in rats. Neuroscience letters. 2014 July 25;576:88-92. PubMed PMID: 24915296; PubMed Central PMCID: PMC4096604.

                  Lin L, Ma C, Wei B, Aziz N, Rajalingam R, Yusung S, Erlich HA, Trachtenberg EA, Targan SR, McGovern DP, Heath JR, Braun J. Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function. Journal of immunology (Baltimore, Md. : 1950). 2014 July 15;193(2):940-9. PubMed PMID: 24935928; PubMed Central PMCID: PMC4096688.

                  Gupta A, Kilpatrick L, Labus J, Tillisch K, Braun A, Hong JY, Ashe-McNalley C, Naliboff B, Mayer EA. Early adverse life events and resting state neural networks in patients with chronic abdominal pain: evidence for sex differences. Psychosomatic medicine. 2014 July;76(6):404-12. PubMed PMID: 25003944; PubMed Central PMCID: PMC4113723.

                  Inoue T, Higashiyama M, Kaji I, Rudenkyy S, Higuchi K, Guth PH, Engel E, Kaunitz JD, Akiba Y. Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats. Digestive diseases and sciences. 2014 June;59(6):1286-95. PubMed PMID: 24379150; PubMed Central PMCID: PMC4196264.

                  Sallam T, Ito A, Rong X, Kim J, van Stijn C, Chamberlain BT, Jung ME, Chao LC, Jones M, Gilliland T, Wu X, Su GL, Tangirala RK, Tontonoz P, Hong C. The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis. Journal of lipid research. 2014 June;55(6):1120-30. PubMed PMID: 24671012; PubMed Central PMCID: PMC4031943.

                  Chen W, McRoberts JA, Marvizón JC. μ-Opioid receptor inhibition of substance P release from primary afferents disappears in neuropathic pain but not inflammatory pain. Neuroscience. 2014 May 16;267:67-82. PubMed PMID: 24583035; PubMed Central PMCID: PMC3998911.

                  Sinnett-Smith J, Ni Y, Wang J, Ming M, Young SH, Rozengurt E. Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling. American journal of physiology. Cell physiology. 2014 May 15;306(10):C961-71. PubMed PMID: 24647541; PubMed Central PMCID: PMC4024715.

                  Chen W, Walwyn W, Ennes HS, Kim H, McRoberts JA, Marvizón JC. BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals. The European journal of neuroscience. 2014 May;39(9):1439-54. PubMed PMID: 24611998; PubMed Central PMCID: PMC4122572.

                  Kilpatrick LA, Coveleskie K, Connolly L, Labus JS, Ebrat B, Stains J, Jiang Z, Suyenobu BY, Raybould HE, Tillisch K, Mayer EA. Influence of sucrose ingestion on brainstem and hypothalamic intrinsic oscillations in lean and obese women. Gastroenterology. 2014 May;146(5):1212-21. PubMed PMID: 24480616; PubMed Central PMCID: PMC4113508.

                  Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle. Virology. 2014 April;454-455:118-27. PubMed PMID: 24725938; PubMed Central PMCID: PMC4011396.

                  Mulak A, Taché Y, Larauche M. Sex hormones in the modulation of irritable bowel syndrome. World journal of gastroenterology. 2014 March 14;20(10):2433-48. PubMed PMID: 24627581; PubMed Central PMCID: PMC3949254.

                  Du S, Itoh N, Askarinam S, Hill H, Arnold AP, Voskuhl RR. XY sex chromosome complement, compared with XX, in the CNS confers greater neurodegeneration during experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 2014 February 18;111(7):2806-11. PubMed PMID: 24550311; PubMed Central PMCID: PMC3932937.

                  Abad C, Nobuta H, Li J, Kasai A, Yong WH, Waschek JA. Targeted STAT3 disruption in myeloid cells alters immunosuppressor cell abundance in a murine model of spontaneous medulloblastoma. Journal of leukocyte biology. 2014 February;95(2):357-67. PubMed PMID: 24068730; PubMed Central PMCID: PMC3896661.

                  Goebel-Stengel M, Stengel A, Wang L, Taché Y. Orexigenic response to tail pinch: role of brain NPY(1) and corticotropin releasing factor receptors. American journal of physiology. Regulatory, integrative and comparative physiology. 2014 February 1;306(3):R164-74. PubMed PMID: 24338440; PubMed Central PMCID: PMC3921301.

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                  Labus JS, Dinov ID, Jiang Z, Ashe-McNalley C, Zamanyan A, Shi Y, Hong JY, Gupta A, Tillisch K, Ebrat B, Hobel S, Gutman BA, Joshi S, Thompson PM, Toga AW, Mayer EA. Irritable bowel syndrome in female patients is associated with alterations in structural brain networks. Pain. 2014 January;155(1):137-49. PubMed PMID: 24076048; PubMed Central PMCID: PMC4100785.

                  Lei NY, Jabaji Z, Wang J, Joshi VS, Brinkley GJ, Khalil H, Wang F, Jaroszewicz A, Pellegrini M, Li L, Lewis M, Stelzner M, Dunn JC, Martín MG. Intestinal subepithelial myofibroblasts support the growth of intestinal epithelial stem cells. PloS one. 2014;9(1):e84651. PubMed PMID: 24400106; PubMed Central PMCID: PMC3882257.

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                  Ming M, Sinnett-Smith J, Wang J, Soares HP, Young SH, Eibl G, Rozengurt E. Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. PloS one. 2014;9(12):e114573. PubMed PMID: 25493642; PubMed Central PMCID: PMC4262417.

                  Richardson-Harman N, Hendrix CW, Bumpus NN, Mauck C, Cranston RD, Yang K, Elliott J, Tanner K, McGowan I, Kashuba A, Anton PA. Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study. PloS one. 2014;9(10):e111507. PubMed PMID: 25350130; PubMed Central PMCID: PMC4211741.

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                  Stengel A, Taché Y. CRF and urocortin peptides as modulators of energy balance and feeding behavior during stress. Frontiers in neuroscience. 2014;8:52. PubMed PMID: 24672423; PubMed Central PMCID: PMC3957495.

                  Su AM, Shih W, Presson AP, Chang L. Characterization of symptoms in irritable bowel syndrome with mixed bowel habit pattern. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 January;26(1):36-45. PubMed PMID: 23991913; PubMed Central PMCID: PMC3865067.

                  Vegezzi G, Anselmi L, Huynh J, Barocelli E, Rozengurt E, Raybould H, Sternini C. Diet-induced regulation of bitter taste receptor subtypes in the mouse gastrointestinal tract. PloS one. 2014;9(9):e107732. PubMed PMID: 25238152; PubMed Central PMCID: PMC4169553.

                  Vu JP, Million M, Larauche M, Luong L, Norris J, Waschek JA, Pothoulakis C, Pisegna JR, Germano PM. Inhibition of vasoactive intestinal polypeptide (VIP) induces resistance to dextran sodium sulfate (DSS)-induced colitis in mice. Journal of molecular neuroscience : MN. 2014 January;52(1):37-47. PubMed PMID: 24395090; PubMed Central PMCID: PMC4114158.

                  Zhou G, Sinnett-Smith J, Liu SH, Yu J, Wu J, Sanchez R, Pandol SJ, Abrol R, Nemunaitis J, Rozengurt E, Brunicardi FC. Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin. Frontiers in physiology. 2014;5:226. PubMed PMID: 25009500; PubMed Central PMCID: PMC4069483.

                  Ke B, Shen XD, Zhang Y, Ji H, Gao F, Yue S, Kamo N, Zhai Y, Yamamoto M, Busuttil RW, Kupiec-Weglinski JW. KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants. Journal of hepatology. 2013 December;59(6):1200-7. PubMed PMID: 23867319; PubMed Central PMCID: PMC4524560.

                  Marcus EA, Vagin O, Tokhtaeva E, Sachs G, Scott DR. Helicobacter pylori impedes acid-induced tightening of gastric epithelial junctions. American journal of physiology. Gastrointestinal and liver physiology. 2013 November 15;305(10):G731-9. PubMed PMID: 23989011; PubMed Central PMCID: PMC3840231.

                  Cheng P, Shih W, Alberto M, Presson AP, Licudine A, Mayer EA, Naliboff BD, Chang L. Autonomic response to a visceral stressor is dysregulated in irritable bowel syndrome and correlates with duration of disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2013 October;25(10):e650-9. PubMed PMID: 23822743; PubMed Central PMCID: PMC3788031.

                  Dawson DW, Hertzer K, Moro A, Donald G, Chang HH, Go VL, Pandol SJ, Lugea A, Gukovskaya AS, Li G, Hines OJ, Rozengurt E, Eibl G. High-fat, high-calorie diet promotes early pancreatic neoplasia in the conditional KrasG12D mouse model. Cancer prevention research (Philadelphia, Pa.). 2013 October;6(10):1064-73. PubMed PMID: 23943783; PubMed Central PMCID: PMC3835151.

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                  Kisfalvi K, Moro A, Sinnett-Smith J, Eibl G, Rozengurt E. Metformin inhibits the growth of human pancreatic cancer xenografts. Pancreas. 2013 July;42(5):781-5. PubMed PMID: 23462329; PubMed Central PMCID: PMC3681894.

                  Sinnett-Smith J, Kisfalvi K, Kui R, Rozengurt E. Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK. Biochemical and biophysical research communications. 2013 January 4;430(1):352-7. PubMed PMID: 23159620; PubMed Central PMCID: PMC3545113.

                  Waldron RT, Innamorati G, Torres-Marquez ME, Sinnett-Smith J, Rozengurt E. Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq. Cellular signalling. 2012 April;24(4):914-21. PubMed PMID: 22227248; PubMed Central PMCID: PMC3286641.

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                  Rozengurt E. Protein kinase D signaling: multiple biological functions in health and disease. Physiology (Bethesda, Md.). 2011 February;26(1):23-33. PubMed PMID: 21357900; PubMed Central PMCID: PMC4381749.

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                  Young SH, Rozengurt E. Crosstalk between insulin receptor and G protein-coupled receptor signaling systems leads to Ca²+ oscillations in pancreatic cancer PANC-1 cells. Biochemical and biophysical research communications. 2010 October 8;401(1):154-8. PubMed PMID: 20849815; PubMed Central PMCID: PMC2952715.

                  Harikumar KB, Kunnumakkara AB, Ochi N, Tong Z, Deorukhkar A, Sung B, Kelland L, Jamieson S, Sutherland R, Raynham T, Charles M, Bagherzadeh A, Foxton C, Boakes A, Farooq M, Maru D, Diagaradjane P, Matsuo Y, Sinnett-Smith J, Gelovani J, Krishnan S, Aggarwal BB, Rozengurt E, Ireson CR, Guha S. A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo. Molecular cancer therapeutics. 2010 May;9(5):1136-46. PubMed PMID: 20442301; PubMed Central PMCID: PMC2905628.

                  Kisfalvi K, Hurd C, Guha S, Rozengurt E. Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells. Journal of cellular physiology. 2010 May;223(2):309-16. PubMed PMID: 20082306; PubMed Central PMCID: PMC2888293.

                  Rozengurt E, Sinnett-Smith J, Kisfalvi K. Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2010 May 1;16(9):2505-11. PubMed PMID: 20388847; PubMed Central PMCID: PMC2862089.

                  Weinberg BM, Spiegel BM, Tomlinson JS, Farrell JJ. Asymptomatic pancreatic cystic neoplasms: maximizing survival and quality of life using Markov-based clinical nomograms. Gastroenterology. 2010 February;138(2):531-40. PubMed PMID: 19818780; PubMed Central PMCID: PMC2949077.

                  Torres-Marquez E, Sinnett-Smith J, Guha S, Kui R, Waldron RT, Rey O, Rozengurt E. CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway. Biochemical and biophysical research communications. 2010 January 1;391(1):63-8. PubMed PMID: 19896460; PubMed Central PMCID: PMC2812606.

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                  Jiang X, Sinnett-Smith J, Rozengurt E. Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. Biochemical and biophysical research communications. 2009 September 25;387(3):521-4. PubMed PMID: 19615971; PubMed Central PMCID: PMC2754135.

                  Kisfalvi K, Eibl G, Sinnett-Smith J, Rozengurt E. Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer research. 2009 August 15;69(16):6539-45. PubMed PMID: 19679549; PubMed Central PMCID: PMC2753241.

                  Spiegel BM, Farid M, van Oijen MG, Laine L, Howden CW, Esrailian E. Adherence to best practice guidelines in dyspepsia: a survey comparing dyspepsia experts, community gastroenterologists and primary-care providers. Alimentary pharmacology & therapeutics. 2009 April 15;29(8):871-81. PubMed PMID: 19183152; PubMed Central PMCID: PMC2953468.

                  Desai AA, Bolus R, Nissenson A, Chertow GM, Bolus S, Solomon MD, Khawar OS, Talley J, Spiegel BM. Is there "cherry picking" in the ESRD Program? Perceptions from a Dialysis Provider Survey. Clinical journal of the American Society of Nephrology : CJASN. 2009 April;4(4):772-7. PubMed PMID: 19339407; PubMed Central PMCID: PMC2666440.

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                  McConalogue K, Grady EF, Minnis J, Balestra B, Tonini M, Brecha NC, Bunnett NW, Sternini C. Activation and internalization of the mu-opioid receptor by the newly discovered endogenous agonists, endomorphin-1 and endomorphin-2. Neuroscience. 1999 March;90(3):1051-9. PubMed PMID: 10218804; PubMed Central PMCID: PMC4472477

  Condro MC, Matynia A, Foster NN, Ago Y, Rajbhandari AK, Van C, Jayaram B, Parikh S, Diep AL, Nguyen E, May V, Dong HW, Waschek JA. High-resolution characterization of a PACAP-EGFP transgenic mouse model for mapping PACAP-expressing neurons. The Journal of comparative neurology. 2016 December 15;524(18):3827-3848. PubMed PMID: 27197019; PubMed Central PMCID: PMC5063673.

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                  Hoang-Yen Tran D, Hoang-Ngoc Tran D, Mattai SA, Sallam T, Ortiz C, Lee EC, Robbins L, Ho S, Lee JE, Fisseha E, Shieh C, Sideri A, Shih DQ, Fleshner P, McGovern DP, Vu M, Hing TC, Bakirtzi K, Cheng M, Su B, Law I, Karagiannides I, Targan SR, Gallo RL, Li Z, Koon HW. Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. International journal of obesity (2005). 2016 September;40(9):1424-34. PubMed PMID: 27163748; PubMed Central PMCID: PMC5014693.

                  Million M, Larauche M. Stress, sex, and the enteric nervous system. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 September;28(9):1283-9. PubMed PMID: 27561694; PubMed Central PMCID: PMC5003424.

                  Padua D, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih D, Iliopoulos D, Pothoulakis C. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. American journal of physiology. Gastrointestinal and liver physiology. 2016 September 1;311(3):G446-57. PubMed PMID: 27492330; PubMed Central PMCID: PMC5076004.

                  Wang J, Sinnett-Smith J, Stevens JV, Young SH, Rozengurt E. Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD). The Journal of biological chemistry. 2016 August 19;291(34):17988-8005. PubMed PMID: 27369082; PubMed Central PMCID: PMC5016186.

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                  Antonios JP, Soto H, Everson RG, Orpilla J, Moughon D, Shin N, Sedighim S, Yong WH, Li G, Cloughesy TF, Liau LM, Prins RM. PD-1 blockade enhances the vaccination-induced immune response in glioma. JCI insight. 2016 July 7;1(10). PubMed PMID: 27453950; PubMed Central PMCID: PMC4951098.

                  Khalil HA, Lei NY, Brinkley G, Scott A, Wang J, Kar UK, Jabaji ZB, Lewis M, Martín MG, Dunn JC, Stelzner MG. A novel culture system for adult porcine intestinal crypts. Cell and tissue research. 2016 July;365(1):123-34. PubMed PMID: 26928041; PubMed Central PMCID: PMC4919165.

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                  Kaji I, Akiba Y, Konno K, Watanabe M, Kimura S, Iwanaga T, Kuri A, Iwamoto K, Kuwahara A, Kaunitz JD. Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon. The Journal of physiology. 2016 June 15;594(12):3339-52. PubMed PMID: 26854275; PubMed Central PMCID: PMC4908031.

                  Holschneider DP, Guo Y, Mayer EA, Wang Z. Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats. Neurobiology of stress. 2016 June 1;3:8-22. PubMed PMID: 26751119; PubMed Central PMCID: PMC4700548.

                  Padua D, Vu JP, Germano PM, Pisegna JR. The Role of Neuropeptides in Mouse Models of Colitis. Journal of molecular neuroscience : MN. 2016 June;59(2):203-10. PubMed PMID: 26646243; PubMed Central PMCID: PMC4884658.

                  Scott A, Rouch JD, Jabaji Z, Khalil HA, Solorzano S, Lewis M, Martín MG, Stelzner MG, Dunn JC. Long-term renewable human intestinal epithelial stem cells as monolayers: A potential for clinical use. Journal of pediatric surgery. 2016 June;51(6):995-1000. PubMed PMID: 26995514; PubMed Central PMCID: PMC4921284.

                  Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. 2016 June;159(6):1520-1527. PubMed PMID: 26847803; PubMed Central PMCID: PMC4856542.

                  Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. American journal of physiology. Gastrointestinal and liver physiology. 2016 June 1;310(11):G1124-37. PubMed PMID: 27151939; PubMed Central PMCID: PMC5005285.

                  Yu J, Liu SH, Sanchez R, Nemunaitis J, Rozengurt E, Brunicardi FC. PDX1 associated therapy in translational medicine. Annals of translational medicine. 2016 June;4(11):214. PubMed PMID: 27386488; PubMed Central PMCID: PMC4916355.

                  Bakirtzi K, Law IK, Xue X, Iliopoulos D, Shah YM, Pothoulakis C. Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling. Journal of immunology (Baltimore, Md. : 1950). 2016 May 15;196(10):4311-21. PubMed PMID: 27076683; PubMed Central PMCID: PMC4868643.

                  Deriu E, Boxx GM, He X, Pan C, Benavidez SD, Cen L, Rozengurt N, Shi W, Cheng G. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS pathogens. 2016 May;12(5):e1005572. PubMed PMID: 27149619; PubMed Central PMCID: PMC4858270.

                  Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Molecular cancer research : MCR. 2016 May;14(5):437-47. PubMed PMID: 26979711; PubMed Central PMCID: PMC4867256.

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                  Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Science translational medicine. 2016 April 13;8(334):334ra54. PubMed PMID: 27075628; PubMed Central PMCID: PMC4934679.

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                  Gupta A, Labus J, Kilpatrick LA, Bonyadi M, Ashe-McNalley C, Heendeniya N, Bradesi S, Chang L, Mayer EA. Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females. Brain structure & function. 2016 April;221(3):1667-79. PubMed PMID: 25630611; PubMed Central PMCID: PMC4573367.

                  Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly. International journal of antimicrobial agents. 2016 April;47(4):289-96. PubMed PMID: 27013001; PubMed Central PMCID: PMC4833571.

                  Wang J, Han L, Sinnett-Smith J, Han LL, Stevens JV, Rozengurt N, Young SH, Rozengurt E. Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552. American journal of physiology. Cell physiology. 2016 April 1;310(7):C542-57. PubMed PMID: 26739494; PubMed Central PMCID: PMC4824155.

                  Yuan PQ, Wu SV, Pothoulakis C, Taché Y. Urocortins and CRF receptor type 2 variants in the male rat colon: gene expression and regulation by endotoxin and anti-inflammatory effect. American journal of physiology. Gastrointestinal and liver physiology. 2016 March 15;310(6):G387-98. PubMed PMID: 26744472; PubMed Central PMCID: PMC4796293.

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                  Mahurkar S, Polytarchou C, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 March;28(3):410-22. PubMed PMID: 26670691; PubMed Central PMCID: PMC4760882.

                  Law IK, Jensen D, Bunnett NW, Pothoulakis C. Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin. Scientific reports. 2016 February 23;6:22195. PubMed PMID: 26902265; PubMed Central PMCID: PMC4763298.

                  Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi K, Dulai GS, Machicado GA. Natural history of definitive diverticular hemorrhage based on stigmata of recent hemorrhage and colonoscopic Doppler blood flow monitoring for risk stratification and definitive hemostasis. Gastrointestinal endoscopy. 2016 February;83(2):416-23. PubMed PMID: 26227931; PubMed Central PMCID: PMC4715947.

                  Walwyn WM, Chen W, Kim H, Minasyan A, Ennes HS, McRoberts JA, Marvizón JC. Sustained Suppression of Hyperalgesia during Latent Sensitization by μ-, δ-, and κ-opioid receptors and α2A Adrenergic Receptors: Role of Constitutive Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2016 January 6;36(1):204-21. PubMed PMID: 26740662; PubMed Central PMCID: PMC4701961.

                  Birtolo C, Go VL, Ptasznik A, Eibl G, Pandol SJ. Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas. 2016 January;45(1):21-31. PubMed PMID: 26658038; PubMed Central PMCID: PMC4859755.

                  Camus M, Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi KA, Machicado GA, Dulai GS, Jensen ME, Gornbein JA. Comparison of Three Risk Scores to Predict Outcomes of Severe Lower Gastrointestinal Bleeding. Journal of clinical gastroenterology. 2016 January;50(1):52-8. PubMed PMID: 25599218; PubMed Central PMCID: PMC4504830.

                  Hoffman JM, Baritaki S, Ruiz JJ, Sideri A, Pothoulakis C. Corticotropin-Releasing Hormone Receptor 2 Signaling Promotes Mucosal Repair Responses after Colitis. The American journal of pathology. 2016 January;186(1):134-44. PubMed PMID: 26597886; PubMed Central PMCID: PMC4714033.

                  Hong JY, Naliboff B, Labus JS, Gupta A, Kilpatrick LA, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Mayer EA. Altered brain responses in subjects with irritable bowel syndrome during cued and uncued pain expectation. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 January;28(1):127-38. PubMed PMID: 26526698; PubMed Central PMCID: PMC4943658.

                  Jarcho JM, Feier NA, Labus JS, Naliboff B, Smith SR, Hong JY, Colloca L, Tillisch K, Mandelkern MA, Mayer EA, London ED. Placebo analgesia: Self-report measures and preliminary evidence of cortical dopamine release associated with placebo response. NeuroImage. Clinical. 2016;10:107-14. PubMed PMID: 26759785; PubMed Central PMCID: PMC4683423.

                  Jensen DM, Ohning GV, Kovacs TO, Ghassemi KA, Jutabha R, Dulai GS, Machicado GA. Doppler endoscopic probe as a guide to risk stratification and definitive hemostasis of peptic ulcer bleeding. Gastrointestinal endoscopy. 2016 January;83(1):129-36. PubMed PMID: 26318834; PubMed Central PMCID: PMC4691549.

                  Labus JS, Naliboff B, Kilpatrick L, Liu C, Ashe-McNalley C, dos Santos IR, Alaverdyan M, Woodworth D, Gupta A, Ellingson BM, Tillisch K, Mayer EA. Pain and Interoception Imaging Network (PAIN): A multimodal, multisite, brain-imaging repository for chronic somatic and visceral pain disorders. NeuroImage. 2016 January 1;124(Pt B):1232-7. PubMed PMID: 25902408; PubMed Central PMCID: PMC4627849.

                  Latorre R, Huynh J, Mazzoni M, Gupta A, Bonora E, Clavenzani P, Chang L, Mayer EA, De Giorgio R, Sternini C. Expression of the Bitter Taste Receptor, T2R38, in Enteroendocrine Cells of the Colonic Mucosa of Overweight/Obese vs. Lean Subjects. PloS one. 2016;11(2):e0147468. PubMed PMID: 26866366; PubMed Central PMCID: PMC4750998.

                  Moussaoui N, Larauche M, Biraud M, Molet J, Million M, Mayer E, Taché Y. Limited Nesting Stress Alters Maternal Behavior and In Vivo Intestinal Permeability in Male Wistar Pup Rats. PloS one. 2016;11(5):e0155037. PubMed PMID: 27149676; PubMed Central PMCID: PMC4858303.

                  Rouch JD, Scott A, Lei NY, Solorzano-Vargas RS, Wang J, Hanson EM, Kobayashi M, Lewis M, Stelzner MG, Dunn JC, Eckmann L, Martín MG. Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. PloS one. 2016;11(1):e0148216. PubMed PMID: 26820624; PubMed Central PMCID: PMC4731053.

                  Zhou G, Yu J, Wang A, Liu SH, Sinnett-Smith J, Wu J, Sanchez R, Nemunaitis J, Ricordi C, Rozengurt E, Brunicardi FC. Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma. Current molecular medicine. 2016;16(1):83-90. PubMed PMID: 26695692; PubMed Central PMCID: PMC4994969.

                  Vuong HE, Hardi CN, Barnes S, Brecha NC. Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 December 2;35(48):15955-70. PubMed PMID: 26631476; PubMed Central PMCID: PMC4666919.

                  Kilpatrick LA, Istrin JJ, Gupta A, Naliboff BD, Tillisch K, Labus JS, Mayer EA. Sex commonalities and differences in the relationship between resilient personality and the intrinsic connectivity of the salience and default mode networks. Biological psychology. 2015 December;112:107-15. PubMed PMID: 26440126; PubMed Central PMCID: PMC5012423.

                  Phan J, Benhammou JN, Pisegna JR. Gastric Hypersecretory States: Investigation and Management. Current treatment options in gastroenterology. 2015 December;13(4):386-97. PubMed PMID: 26342486; PubMed Central PMCID: PMC4633316.

                  Stark AP, Chang HH, Jung X, Moro A, Hertzer K, Xu M, Schmidt A, Hines OJ, Eibl G. E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice. Surgery. 2015 December;158(6):1564-72. PubMed PMID: 26297056; PubMed Central PMCID: PMC4637247.

                  Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of experimental medicine. 2015 November 16;212(12):2147-63. PubMed PMID: 26552708; PubMed Central PMCID: PMC4647265.

                  Chang HH, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G. Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1. American journal of physiology. Cell physiology. 2015 November 15;309(10):C639-49. PubMed PMID: 26310818; PubMed Central PMCID: PMC4652080.

                  Vu JP, Goyal D, Luong L, Oh S, Sandhu R, Norris J, Parsons W, Pisegna JR, Germano PM. PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin. American journal of physiology. Gastrointestinal and liver physiology. 2015 November 15;309(10):G816-25. PubMed PMID: 26336928; PubMed Central PMCID: PMC4652141.

                  Young SH, Rey O, Rozengurt E. Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: Impact of the highly conservative mutation Ser170Thr. Biochemical and biophysical research communications. 2015 November 6;467(1):1-6. PubMed PMID: 26431875; PubMed Central PMCID: PMC4613767.

                  Rodriguez JA, Huerta-Yepez S, Law IK, Baay-Guzman GJ, Tirado-Rodriguez B, Hoffman JM, Iliopoulos D, Hommes DW, Verspaget HW, Chang L, Pothoulakis C, Baritaki S. Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling. Cellular and molecular gastroenterology and hepatology. 2015 November 1;1(6):610-630. PubMed PMID: 26495412; PubMed Central PMCID: PMC4610032.

                  Vuong HE, Pérez de Sevilla Müller L, Hardi CN, McMahon DG, Brecha NC. Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines. Neuroscience. 2015 October 29;307:319-37. PubMed PMID: 26335381; PubMed Central PMCID: PMC4603663.

                  Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D. MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice. Gastroenterology. 2015 October;149(4):981-92.e11. PubMed PMID: 26055138; PubMed Central PMCID: PMC4584179.

                  Fang K, Sideri A, Law IK, Bakirtzi K, Polytarchou C, Iliopoulos D, Pothoulakis C. Identification of a novel substance P (SP)-neurokinin-1 receptor (NK-1R) microRNA-221-5p inflammatory network in human colonic epithelial cells. Cellular and molecular gastroenterology and hepatology. 2015 September 1;1(5):503-515. PubMed PMID: 26645045; PubMed Central PMCID: PMC4669978.

                  Hubbard CS, Hong J, Jiang Z, Ebrat B, Suyenobu B, Smith S, Heendeniya N, Naliboff BD, Tillisch K, Mayer EA, Labus JS. Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 September;27(9):1282-94. PubMed PMID: 26087779; PubMed Central PMCID: PMC4550526.

                  Cherukuri DP, Deignan JL, Das K, Grody WW, Herschman H. Instability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma. Molecular oncology. 2015 August;9(7):1252-8. PubMed PMID: 25817443; PubMed Central PMCID: PMC4523444.

                  Irimia A, Labus JS, Torgerson CM, Van Horn JD, Mayer EA. Altered viscerotopic cortical innervation in patients with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 August;27(8):1075-81. PubMed PMID: 25952540; PubMed Central PMCID: PMC4520752.

                  Kaunitz JD. The Discovery of PCR: ProCuRement of Divine Power. Digestive diseases and sciences. 2015 August;60(8):2230-1. PubMed PMID: 26077976; PubMed Central PMCID: PMC4501591.

                  Kobayashi M, Lei NY, Wang Q, Wu BM, Dunn JC. Orthogonally oriented scaffolds with aligned fibers for engineering intestinal smooth muscle. Biomaterials. 2015 August;61:75-84. PubMed PMID: 26001072; PubMed Central PMCID: PMC4464968.

                  Labus JS, Van Horn JD, Gupta A, Alaverdyan M, Torgerson C, Ashe-McNalley C, Irimia A, Hong JY, Naliboff B, Tillisch K, Mayer EA. Multivariate morphological brain signatures predict patients with chronic abdominal pain from healthy control subjects. Pain. 2015 August;156(8):1545-54. PubMed PMID: 25906347; PubMed Central PMCID: PMC4504800.

                  O'Mahony F, Wroblewski K, O'Byrne SM, Jiang H, Clerkin K, Benhammou J, Blaner WS, Beaven SW. Liver X receptors balance lipid stores in hepatic stellate cells through Rab18, a retinoid responsive lipid droplet protein. Hepatology (Baltimore, Md.). 2015 August;62(2):615-26. PubMed PMID: 25482505; PubMed Central PMCID: PMC4458237.

                  Tuominen I, Beaven SW. Intestinal farnesoid X receptor puts a fresh coat of wax on fatty liver. Hepatology (Baltimore, Md.). 2015 August;62(2):646-8. PubMed PMID: 25998695; PubMed Central PMCID: PMC4523235.

                  Law IK, Bakirtzi K, Polytarchou C, Oikonomopoulos A, Hommes D, Iliopoulos D, Pothoulakis C. Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis. Gut. 2015 July;64(7):1095-104. PubMed PMID: 25112884; PubMed Central PMCID: PMC4422787.

                  Lugea A, Waldron RT, Pandol SJ. Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2015 July;15(4 Suppl):S1-5. PubMed PMID: 25736240; PubMed Central PMCID: PMC4515411.

                  Stengel A, Karasawa H, Taché Y. The role of brain somatostatin receptor 2 in the regulation of feeding and drinking behavior. Hormones and behavior. 2015 July;73:15-22. PubMed PMID: 26026616; PubMed Central PMCID: PMC4546908.

                  Sanmiguel C, Gupta A, Mayer EA. Gut Microbiome and Obesity: A Plausible Explanation for Obesity. Current obesity reports. 2015 June;4(2):250-61. PubMed PMID: 26029487; PubMed Central PMCID: PMC4443745.

                  Vu JP, Larauche M, Flores M, Luong L, Norris J, Oh S, Liang LJ, Waschek J, Pisegna JR, Germano PM. Regulation of Appetite, Body Composition, and Metabolic Hormones by Vasoactive Intestinal Polypeptide (VIP). Journal of molecular neuroscience : MN. 2015 June;56(2):377-87. PubMed PMID: 25904310; PubMed Central PMCID: PMC4458420.

                  Gupta A, Rapkin AJ, Gill Z, Kilpatrick L, Fling C, Stains J, Masghati S, Tillisch K, Mayer EA, Labus JS. Disease-related differences in resting-state networks: a comparison between localized provoked vulvodynia, irritable bowel syndrome, and healthy control subjects. Pain. 2015 May;156(5):809-19. PubMed PMID: 25735001; PubMed Central PMCID: PMC4402252.

                  Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D. A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. Inflammatory bowel diseases. 2015 May;21(5):996-1005. PubMed PMID: 25738378; PubMed Central PMCID: PMC4402238.

                  Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JC, Martin MG, Lagasse E, Zhang L, Yu J. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Scientific reports. 2015 April 10;5:8566. PubMed PMID: 25858503; PubMed Central PMCID: PMC4392360.

                  Wu JX, Liu SH, Nemunaitis JJ, Brunicardi FC. Liposomal insulin promoter-thymidine kinase gene therapy followed by ganciclovir effectively ablates human pancreatic cancer in mice. Cancer letters. 2015 April 10;359(2):206-10. PubMed PMID: 25596375; PubMed Central PMCID: PMC4336837.

                  Akiba Y, Kaunitz JD, Million M. Peripheral corticotropin-releasing factor receptor type 2 activation increases colonic blood flow through nitric oxide pathway in rats. Digestive diseases and sciences. 2015 April;60(4):858-67. PubMed PMID: 25701320; PubMed Central PMCID: PMC4501405.

                  Anselmi L, Huynh J, Duraffourd C, Jaramillo I, Vegezzi G, Saccani F, Boschetti E, Brecha NC, De Giorgio R, Sternini C. Activation of μ opioid receptors modulates inflammation in acute experimental colitis. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 April;27(4):509-23. PubMed PMID: 25690069; PubMed Central PMCID: PMC4405133.

                  Liu Z, Sun F, Braun J, McGovern DP, Piantadosi S. Multilevel regularized regression for simultaneous taxa selection and network construction with metagenomic count data. Bioinformatics (Oxford, England). 2015 April 1;31(7):1067-74. PubMed PMID: 25416747; PubMed Central PMCID: PMC4382903.

                  Marvizon JC, Walwyn W, Minasyan A, Chen W, Taylor BK. Latent sensitization: a model for stress-sensitive chronic pain. Current protocols in neuroscience. 2015 April 1;71:9.50.1-14. PubMed PMID: 25829356; PubMed Central PMCID: PMC4532319.

                  Mayer EA, Gupta A, Kilpatrick LA, Hong JY. Imaging brain mechanisms in chronic visceral pain. Pain. 2015 April;156 Suppl 1:S50-63. PubMed PMID: 25789437; PubMed Central PMCID: PMC4428597.

                  Sideri A, Stavrakis D, Bowe C, Shih DQ, Fleshner P, Arsenescu V, Arsenescu R, Turner JR, Pothoulakis C, Karagiannides I. Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1. American journal of physiology. Gastrointestinal and liver physiology. 2015 April 1;308(7):G591-604. PubMed PMID: 25591865; PubMed Central PMCID: PMC4385897.

                  Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2. Molecular cancer therapeutics. 2015 April;14(4):1014-23. PubMed PMID: 25673820; PubMed Central PMCID: PMC4394038.

                  Tarling EJ, Ahn H, de Aguiar Vallim TQ. The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2. Arteriosclerosis, thrombosis, and vascular biology. 2015 April;35(4):787-95. PubMed PMID: 25593129; PubMed Central PMCID: PMC4376635.

                  Gukovsky I, Gukovskaya AS. Impaired autophagy triggers chronic pancreatitis: lessons from pancreas-specific atg5 knockout mice. Gastroenterology. 2015 March;148(3):501-5. PubMed PMID: 25613315; PubMed Central PMCID: PMC4443443.

                  Liu Y, Ji H, Zhang Y, Shen X, Gao F, He X, Li GA, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury. Journal of hepatology. 2015 March;62(3):563-72. PubMed PMID: 25450716; PubMed Central PMCID: PMC4336640.

                  Sakanaka T, Inoue T, Yorifuji N, Iguchi M, Fujiwara K, Narabayashi K, Kakimoto K, Nouda S, Okada T, Kuramoto T, Ishida K, Abe Y, Takeuchi T, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. The effects of a TGR5 agonist and a dipeptidyl peptidase IV inhibitor on dextran sulfate sodium-induced colitis in mice. Journal of gastroenterology and hepatology. 2015 March;30 Suppl 1:60-5. PubMed PMID: 25827806; PubMed Central PMCID: PMC4874188.

                  Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. The Journal of biological chemistry. 2015 February 27;290(9):5566-81. PubMed PMID: 25468909; PubMed Central PMCID: PMC4342471.

                  Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. Septin dynamics are essential for exocytosis. The Journal of biological chemistry. 2015 February 27;290(9):5280-97. PubMed PMID: 25575596; PubMed Central PMCID: PMC4342448.

                  Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell metabolism. 2015 February 3;21(2):334-46. PubMed PMID: 25651185; PubMed Central PMCID: PMC4349439.

                  de Aguiar Vallim TQ, Tarling EJ, Ahn H, Hagey LR, Romanoski CE, Lee RG, Graham MJ, Motohashi H, Yamamoto M, Edwards PA. MAFG is a transcriptional repressor of bile acid synthesis and metabolism. Cell metabolism. 2015 February 3;21(2):298-310. PubMed PMID: 25651182; PubMed Central PMCID: PMC4317590.

                  Bromley EG, May FP, Federer L, Spiegel BM, van Oijen MG. Explaining persistent under-use of colonoscopic cancer screening in African Americans: a systematic review. Preventive medicine. 2015 February;71:40-8. PubMed PMID: 25481094; PubMed Central PMCID: PMC4329030.

                  Kaji I, Iwanaga T, Watanabe M, Guth PH, Engel E, Kaunitz JD, Akiba Y. SCFA transport in rat duodenum. American journal of physiology. Gastrointestinal and liver physiology. 2015 February 1;308(3):G188-97. PubMed PMID: 25394661; PubMed Central PMCID: PMC4312951.

                  Nguyen AH, Toste PA, Farrell JJ, Clerkin BM, Williams J, Muthusamy VR, Watson RR, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Current recommendations for surveillance and surgery of intraductal papillary mucinous neoplasms may overlook some patients with cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2015 February;19(2):258-65. PubMed PMID: 25373706; PubMed Central PMCID: PMC4305480.

                  Tan YV, Abad C, Wang Y, Lopez R, Waschek J. VPAC2 (vasoactive intestinal peptide receptor type 2) receptor deficient mice develop exacerbated experimental autoimmune encephalomyelitis with increased Th1/Th17 and reduced Th2/Treg responses. Brain, behavior, and immunity. 2015 February;44:167-175. PubMed PMID: 25305591; PubMed Central PMCID: PMC4275378.

                  Taché Y, Million M. Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia. Journal of neurogastroenterology and motility. 2015 January 31;21(1):8-24. PubMed PMID: 25611064; PubMed Central PMCID: PMC4288101.

                  Coveleskie K, Gupta A, Kilpatrick LA, Mayer ED, Ashe-McNalley C, Stains J, Labus JS, Mayer EA. Altered functional connectivity within the central reward network in overweight and obese women. Nutrition & diabetes. 2015 January 19;5:e148. PubMed PMID: 25599560; PubMed Central PMCID: PMC4314578.

                  Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology. 2015 January 15;475:46-55. PubMed PMID: 25462345; PubMed Central PMCID: PMC4284078.

                  Abad C, Cheung-Lau G, Coûté-Monvoisin AC, Waschek JA. Vasoactive intestinal peptide-deficient mice exhibit reduced pathology in trinitrobenzene sulfonic acid-induced colitis. Neuroimmunomodulation. 2015;22(3):203-12. PubMed PMID: 25301381; PubMed Central PMCID: PMC4297532.

                  Bradesi S, Karagiannides I, Bakirtzi K, Joshi SM, Koukos G, Iliopoulos D, Pothoulakis C, Mayer EA. Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat. PloS one. 2015;10(7):e0130938. PubMed PMID: 26222740; PubMed Central PMCID: PMC4519289.

                  Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. Journal of Alzheimer's disease : JAD. 2015;43(3):967-76. PubMed PMID: 25125464; PubMed Central PMCID: PMC4258165.

                  Chen R, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM, Maitra A, Brentnall TA. Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. Laboratory investigation; a journal of technical methods and pathology. 2015 January;95(1):43-55. PubMed PMID: 25347153; PubMed Central PMCID: PMC4281293.

                  Cheng M, Ho S, Yoo JH, Tran DH, Bakirtzi K, Su B, Tran DH, Kubota Y, Ichikawa R, Koon HW. Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts. Clinical and experimental gastroenterology. 2015;8:13-29. PubMed PMID: 25565877; PubMed Central PMCID: PMC4274046.

                  Gupta A, Mayer EA, Sanmiguel CP, Van Horn JD, Woodworth D, Ellingson BM, Fling C, Love A, Tillisch K, Labus JS. Patterns of brain structural connectivity differentiate normal weight from overweight subjects. NeuroImage. Clinical. 2015;7:506-17. PubMed PMID: 25737959; PubMed Central PMCID: PMC4338207.

                  Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 January 1;21(1):157-65. PubMed PMID: 25348515; PubMed Central PMCID: PMC4286535.

                  Khalil HA, Lei NY, Nie W, Lewis MS, Stelzner MG, Martín MG, Dunn JC, Yoo J. Primary Myofibroblasts Maintain Short-Term Viability following Submucosal Injection in Syngeneic, Immune-Competent Mice Utilizing Murine Colonoscopy. PloS one. 2015;10(5):e0127258. PubMed PMID: 26016485; PubMed Central PMCID: PMC4445916.

                  Kutch JJ, Yani MS, Asavasopon S, Kirages DJ, Rana M, Cosand L, Labus JS, Kilpatrick LA, Ashe-McNalley C, Farmer MA, Johnson KA, Ness TJ, Deutsch G, Harris RE, Apkarian AV, Clauw DJ, Mackey SC, Mullins C, Mayer EA. Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study. NeuroImage. Clinical. 2015;8:493-502. PubMed PMID: 26106574; PubMed Central PMCID: PMC4474411.

                  Law IK, Pothoulakis C. MicroRNA-133α regulates neurotensin-associated colonic inflammation in colonic epithelial cells and experimental colitis. RNA & disease (Houston, Tex.). 2015;2(1). PubMed PMID: 26005712; PubMed Central PMCID: PMC4441413.

                  Li Y, Go VL, Sarkar FH. The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome. Pancreas. 2015 January;44(1):1-10. PubMed PMID: 25493373; PubMed Central PMCID: PMC4264839.

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                  Marzagalli R, Scuderi S, Drago F, Waschek JA, Castorina A. Emerging Role of PACAP as a New Potential Therapeutic Target in Major Diabetes Complications. International journal of endocrinology. 2015;2015:160928. PubMed PMID: 26074958; PubMed Central PMCID: PMC4446501.

                  McGowan I, Anton PA, Elliott J, Cranston RD, Duffill K, Althouse AD, Hawkins KL, De Rosa SC. Exploring the feasibility of multi-site flow cytometric processing of gut associated lymphoid tissue with centralized data analysis for multi-site clinical trials. PloS one. 2015;10(5):e0126454. PubMed PMID: 26010577; PubMed Central PMCID: PMC4444258.

                  Mulak A, Larauche M, Biraud M, Million M, Rivier J, Taché Y. Selective agonists of somatostatin receptor subtype 1 or 2 injected peripherally induce antihyperalgesic effect in two models of visceral hypersensitivity in mice. Peptides. 2015 January;63:71-80. PubMed PMID: 25451334; PubMed Central PMCID: PMC4385413.

                  Orand A, Gupta A, Shih W, Presson AP, Hammer C, Niesler B, Heendeniya N, Mayer EA, Chang L. Catecholaminergic Gene Polymorphisms Are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome. PloS one. 2015;10(8):e0135910. PubMed PMID: 26288143; PubMed Central PMCID: PMC4546052.

                  Taché Y. Corticotrophin-releasing factor 1 activation in the central amygdale and visceral hyperalgesia. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 January;27(1):1-6. PubMed PMID: 25557223; PubMed Central PMCID: PMC4389773.

                  Wang L, Mogami S, Yakabi S, Karasawa H, Yamada C, Yakabi K, Hattori T, Taché Y. Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito. PloS one. 2015;10(9):e0139325. PubMed PMID: 26421719; PubMed Central PMCID: PMC4589401.

                  Wang Y, Yan C, Liu L, Wang W, Du H, Fan W, Lutfy K, Jiang M, Friedman TC, Liu Y. 11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue. American journal of physiology. Endocrinology and metabolism. 2015 January 1;308(1):E84-95. PubMed PMID: 25389364; PubMed Central PMCID: PMC4281684.

                  Yoo JH, Ho S, Tran DH, Cheng M, Bakirtzi K, Kukota Y, Ichikawa R, Su B, Tran DH, Hing TC, Chang I, Shih DQ, Issacson RE, Gallo RL, Fiocchi C, Pothoulakis C, Koon HW. Anti-fibrogenic effects of the anti-microbial peptide cathelicidin in murine colitis-associated fibrosis. Cellular and molecular gastroenterology and hepatology. 2015 January;1(1):55-74.e1. PubMed PMID: 25729764; PubMed Central PMCID: PMC4338438.

                  Zhu J, Lu T, Yue S, Shen X, Gao F, Busuttil RW, Kupiec-Weglinski JW, Xia Q, Zhai Y. Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation. Transplantation. 2015 January;99(1):48-55. PubMed PMID: 25340604; PubMed Central PMCID: PMC4272660.

                  Akiba Y, Kaunitz JD. Prostaglandin pathways in duodenal chemosensing. Journal of gastroenterology and hepatology. 2014 December;29 Suppl 4:93-8. PubMed PMID: 25521740; PubMed Central PMCID: PMC4451058.

                  Bagarinao E, Johnson KA, Martucci KT, Ichesco E, Farmer MA, Labus J, Ness TJ, Harris R, Deutsch G, Apkarian AV, Mayer EA, Clauw DJ, Mackey S. Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network study. Pain. 2014 December;155(12):2502-9. PubMed PMID: 25242566; PubMed Central PMCID: PMC4504202.

                  Buzzanco A, Gomez A, Rodriguez E, French BA, Tillman BA, Chang S, Ganapathy E, Junrungsee S, Zarrinpar A, Agopian VG, Naini BV, French SW Jr, French SW Sr. Digital quantitation of HCC-associated stem cell markers and protein quality control factors using tissue arrays of human liver sections. Experimental and molecular pathology. 2014 December;97(3):399-410. PubMed PMID: 25218810; PubMed Central PMCID: PMC4262606.

                  Donahue TR, Nguyen AH, Moughan J, Li L, Tatishchev S, Toste P, Farrell JJ. Stromal microRNA-21 levels predict response to 5-fluorouracil in patients with pancreatic cancer. Journal of surgical oncology. 2014 December;110(8):952-9. PubMed PMID: 25132574; PubMed Central PMCID: PMC4232442.

                  Ji H, Liu Y, Zhang Y, Shen XD, Gao F, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. T-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury. Hepatology (Baltimore, Md.). 2014 December;60(6):2052-2064. PubMed PMID: 25066922; PubMed Central PMCID: PMC4396987.

                  Karasawa H, Pietra C, Giuliano C, Garcia-Rubio S, Xu X, Yakabi S, Taché Y, Wang L. New ghrelin agonist, HM01 alleviates constipation and L-dopa-delayed gastric emptying in 6-hydroxydopamine rat model of Parkinson's disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 December;26(12):1771-82. PubMed PMID: 25327342; PubMed Central PMCID: PMC4457321.

                  Stengel A, Taché Y. Brain peptides and the modulation of postoperative gastric ileus. Current opinion in pharmacology. 2014 December;19:31-7. PubMed PMID: 24999843; PubMed Central PMCID: PMC4254047.

                  Wagner JP, Sullins VF, Dunn JC. Skin-derived precursors generate enteric-type neurons in aganglionic jejunum. Journal of pediatric surgery. 2014 December;49(12):1809-14. PubMed PMID: 25487489; PubMed Central PMCID: PMC4261145.

                  Wagner JP, Sullins VF, Khalil HA, Dunn JC. A durable model of Hirschsprung's colon. Journal of pediatric surgery. 2014 December;49(12):1804-8. PubMed PMID: 25487488; PubMed Central PMCID: PMC4261142.

                  Hong C, Marshall SM, McDaniel AL, Graham M, Layne JD, Cai L, Scotti E, Boyadjian R, Kim J, Chamberlain BT, Tangirala RK, Jung ME, Fong L, Lee R, Young SG, Temel RE, Tontonoz P. The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice. Cell metabolism. 2014 November 4;20(5):910-8. PubMed PMID: 25440061; PubMed Central PMCID: PMC4261644.

                  Tong M, Jacobs JP, McHardy IH, Braun J. Sampling of intestinal microbiota and targeted amplification of bacterial 16S rRNA genes for microbial ecologic analysis. Current protocols in immunology. 2014 November 3;107:7.41.1-11. PubMed PMID: 25367129; PubMed Central PMCID: PMC4457454.

                  Balaji K, French CT, Miller JF, Colicelli J. The RAB5-GEF function of RIN1 regulates multiple steps during Listeria monocytogenes infection. Traffic (Copenhagen, Denmark). 2014 November;15(11):1206-18. PubMed PMID: 25082076; PubMed Central PMCID: PMC4282165.

                  Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR. Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. Molecular cancer research : MCR. 2014 November;12(11):1677-88. PubMed PMID: 25063587; PubMed Central PMCID: PMC4233191.

                  Rozengurt E, Soares HP, Sinnet-Smith J. Suppression of feedback loops mediated by PI3K/mTOR induces multiple overactivation of compensatory pathways: an unintended consequence leading to drug resistance. Molecular cancer therapeutics. 2014 November;13(11):2477-88. PubMed PMID: 25323681; PubMed Central PMCID: PMC4222988.

                  Shih DQ, Zheng L, Zhang X, Zhang H, Kanazawa Y, Ichikawa R, Wallace KL, Chen J, Pothoulakis C, Koon HW, Targan SR. Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis. Mucosal immunology. 2014 November;7(6):1492-503. PubMed PMID: 24850426; PubMed Central PMCID: PMC4205266.

                  Spiegel BM, Hays RD, Bolus R, Melmed GY, Chang L, Whitman C, Khanna PP, Paz SH, Hays T, Reise S, Khanna D. Development of the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) gastrointestinal symptom scales. The American journal of gastroenterology. 2014 November;109(11):1804-14. PubMed PMID: 25199473; PubMed Central PMCID: PMC4285435.

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                  Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Molecular cancer therapeutics. 2014 October;13(10):2303-14. PubMed PMID: 25082960; PubMed Central PMCID: PMC4188417.

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                  Arnold AP. Conceptual frameworks and mouse models for studying sex differences in physiology and disease: why compensation changes the game. Experimental neurology. 2014 September;259:2-9. PubMed PMID: 24509348; PubMed Central PMCID: PMC4125548.

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                  Koon HW, Ho S, Hing TC, Cheng M, Chen X, Ichikawa Y, Kelly CP, Pothoulakis C. Fidaxomicin inhibits Clostridium difficile toxin A-mediated enteritis in the mouse ileum. Antimicrobial agents and chemotherapy. 2014 August;58(8):4642-50. PubMed PMID: 24890583; PubMed Central PMCID: PMC4135997.

                  Ngun TC, Ghahramani NM, Creek MM, Williams-Burris SM, Barseghyan H, Itoh Y, Sánchez FJ, McClusky R, Sinsheimer JS, Arnold AP, Vilain E. Feminized behavior and brain gene expression in a novel mouse model of Klinefelter Syndrome. Archives of sexual behavior. 2014 August;43(6):1043-57. PubMed PMID: 24923877; PubMed Central PMCID: PMC4371776.

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                  Lin L, Ma C, Wei B, Aziz N, Rajalingam R, Yusung S, Erlich HA, Trachtenberg EA, Targan SR, McGovern DP, Heath JR, Braun J. Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function. Journal of immunology (Baltimore, Md. : 1950). 2014 July 15;193(2):940-9. PubMed PMID: 24935928; PubMed Central PMCID: PMC4096688.

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                  Inoue T, Higashiyama M, Kaji I, Rudenkyy S, Higuchi K, Guth PH, Engel E, Kaunitz JD, Akiba Y. Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats. Digestive diseases and sciences. 2014 June;59(6):1286-95. PubMed PMID: 24379150; PubMed Central PMCID: PMC4196264.

                  Sallam T, Ito A, Rong X, Kim J, van Stijn C, Chamberlain BT, Jung ME, Chao LC, Jones M, Gilliland T, Wu X, Su GL, Tangirala RK, Tontonoz P, Hong C. The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis. Journal of lipid research. 2014 June;55(6):1120-30. PubMed PMID: 24671012; PubMed Central PMCID: PMC4031943.

                  Chen W, McRoberts JA, Marvizón JC. μ-Opioid receptor inhibition of substance P release from primary afferents disappears in neuropathic pain but not inflammatory pain. Neuroscience. 2014 May 16;267:67-82. PubMed PMID: 24583035; PubMed Central PMCID: PMC3998911.

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                  Kilpatrick LA, Coveleskie K, Connolly L, Labus JS, Ebrat B, Stains J, Jiang Z, Suyenobu BY, Raybould HE, Tillisch K, Mayer EA. Influence of sucrose ingestion on brainstem and hypothalamic intrinsic oscillations in lean and obese women. Gastroenterology. 2014 May;146(5):1212-21. PubMed PMID: 24480616; PubMed Central PMCID: PMC4113508.

                  Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle. Virology. 2014 April;454-455:118-27. PubMed PMID: 24725938; PubMed Central PMCID: PMC4011396.

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                  Abad C, Nobuta H, Li J, Kasai A, Yong WH, Waschek JA. Targeted STAT3 disruption in myeloid cells alters immunosuppressor cell abundance in a murine model of spontaneous medulloblastoma. Journal of leukocyte biology. 2014 February;95(2):357-67. PubMed PMID: 24068730; PubMed Central PMCID: PMC3896661.

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                  Ming M, Sinnett-Smith J, Wang J, Soares HP, Young SH, Eibl G, Rozengurt E. Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. PloS one. 2014;9(12):e114573. PubMed PMID: 25493642; PubMed Central PMCID: PMC4262417.

                  Richardson-Harman N, Hendrix CW, Bumpus NN, Mauck C, Cranston RD, Yang K, Elliott J, Tanner K, McGowan I, Kashuba A, Anton PA. Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study. PloS one. 2014;9(10):e111507. PubMed PMID: 25350130; PubMed Central PMCID: PMC4211741.

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                  Ke B, Shen XD, Zhang Y, Ji H, Gao F, Yue S, Kamo N, Zhai Y, Yamamoto M, Busuttil RW, Kupiec-Weglinski JW. KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants. Journal of hepatology. 2013 December;59(6):1200-7. PubMed PMID: 23867319; PubMed Central PMCID: PMC4524560.

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                  Guha S, Tanasanvimon S, Sinnett-Smith J, Rozengurt E. Role of protein kinase D signaling in pancreatic cancer. Biochemical pharmacology. 2010 December 15;80(12):1946-54. PubMed PMID: 20621068; PubMed Central PMCID: PMC2974013.

                  Young SH, Rozengurt E. Crosstalk between insulin receptor and G protein-coupled receptor signaling systems leads to Ca²+ oscillations in pancreatic cancer PANC-1 cells. Biochemical and biophysical research communications. 2010 October 8;401(1):154-8. PubMed PMID: 20849815; PubMed Central PMCID: PMC2952715.

                  Harikumar KB, Kunnumakkara AB, Ochi N, Tong Z, Deorukhkar A, Sung B, Kelland L, Jamieson S, Sutherland R, Raynham T, Charles M, Bagherzadeh A, Foxton C, Boakes A, Farooq M, Maru D, Diagaradjane P, Matsuo Y, Sinnett-Smith J, Gelovani J, Krishnan S, Aggarwal BB, Rozengurt E, Ireson CR, Guha S. A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo. Molecular cancer therapeutics. 2010 May;9(5):1136-46. PubMed PMID: 20442301; PubMed Central PMCID: PMC2905628.

                  Kisfalvi K, Hurd C, Guha S, Rozengurt E. Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells. Journal of cellular physiology. 2010 May;223(2):309-16. PubMed PMID: 20082306; PubMed Central PMCID: PMC2888293.

                  Rozengurt E, Sinnett-Smith J, Kisfalvi K. Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2010 May 1;16(9):2505-11. PubMed PMID: 20388847; PubMed Central PMCID: PMC2862089.

                  Weinberg BM, Spiegel BM, Tomlinson JS, Farrell JJ. Asymptomatic pancreatic cystic neoplasms: maximizing survival and quality of life using Markov-based clinical nomograms. Gastroenterology. 2010 February;138(2):531-40. PubMed PMID: 19818780; PubMed Central PMCID: PMC2949077.

                  Torres-Marquez E, Sinnett-Smith J, Guha S, Kui R, Waldron RT, Rey O, Rozengurt E. CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway. Biochemical and biophysical research communications. 2010 January 1;391(1):63-8. PubMed PMID: 19896460; PubMed Central PMCID: PMC2812606.

                  Correction: A Novel Small-Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In vitro and In vivo. Molecular cancer therapeutics. 2010. PubMed Central PMCID: PMC2940835.

                  Jiang X, Sinnett-Smith J, Rozengurt E. Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. Biochemical and biophysical research communications. 2009 September 25;387(3):521-4. PubMed PMID: 19615971; PubMed Central PMCID: PMC2754135.

                  Kisfalvi K, Eibl G, Sinnett-Smith J, Rozengurt E. Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer research. 2009 August 15;69(16):6539-45. PubMed PMID: 19679549; PubMed Central PMCID: PMC2753241.

                  Spiegel BM, Farid M, van Oijen MG, Laine L, Howden CW, Esrailian E. Adherence to best practice guidelines in dyspepsia: a survey comparing dyspepsia experts, community gastroenterologists and primary-care providers. Alimentary pharmacology & therapeutics. 2009 April 15;29(8):871-81. PubMed PMID: 19183152; PubMed Central PMCID: PMC2953468.

                  Desai AA, Bolus R, Nissenson A, Chertow GM, Bolus S, Solomon MD, Khawar OS, Talley J, Spiegel BM. Is there "cherry picking" in the ESRD Program? Perceptions from a Dialysis Provider Survey. Clinical journal of the American Society of Nephrology : CJASN. 2009 April;4(4):772-7. PubMed PMID: 19339407; PubMed Central PMCID: PMC2666440.

                  Spiegel BM, Chey WD, Chang L. Bacterial overgrowth and irritable bowel syndrome: unifying hypothesis or a spurious consequence of proton pump inhibitors?. The American journal of gastroenterology. 2008 December;103(12):2972-6. PubMed PMID: 19086951; PubMed Central PMCID: PMC2949084.

                  Angst E, Reber HA, Hines OJ, Eibl G. Mononuclear cell-derived interleukin-1 beta confers chemoresistance in pancreatic cancer cells by upregulation of cyclooxygenase-2. Surgery. 2008 July;144(1):57-65. PubMed PMID: 18571585; PubMed Central PMCID: PMC2601479.

                  Rozengurt E, Sternini C. Taste receptor signaling in the mammalian gut. Current opinion in pharmacology. 2007 December;7(6):557-62. PubMed PMID: 18024184; PubMed Central PMCID: PMC2753238.

                  McConalogue K, Grady EF, Minnis J, Balestra B, Tonini M, Brecha NC, Bunnett NW, Sternini C. Activation and internalization of the mu-opioid receptor by the newly discovered endogenous agonists, endomorphin-1 and endomorphin-2. Neuroscience. 1999 March;90(3):1051-9. PubMed PMID: 10218804; PubMed Central PMCID: PMC4472477

  Condro MC, Matynia A, Foster NN, Ago Y, Rajbhandari AK, Van C, Jayaram B, Parikh S, Diep AL, Nguyen E, May V, Dong HW, Waschek JA. High-resolution characterization of a PACAP-EGFP transgenic mouse model for mapping PACAP-expressing neurons. The Journal of comparative neurology. 2016 December 15;524(18):3827-3848. PubMed PMID: 27197019; PubMed Central PMCID: PMC5063673.

                  Duboc H, Tolstanova G, Yuan PQ, Wu V, Kaji I, Biraud M, Akiba Y, Kaunitz J, Million M, Tache Y, Larauche M. Reduction of epithelial secretion in male rat distal colonic mucosa by bile acid receptor TGR5 agonist, INT-777: role of submucosal neurons. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 November;28(11):1663-1676. PubMed PMID: 27259385; PubMed Central PMCID: PMC5083223.

                  Orand A, Naliboff B, Gadd M, Shih W, Ju T, Presson AP, Mayer EA, Chang L. Corticotropin-releasing hormone receptor 1 (CRH-R1) polymorphisms are associated with irritable bowel syndrome and acoustic startle response. Psychoneuroendocrinology. 2016 November;73:133-141. PubMed PMID: 27497153; PubMed Central PMCID: PMC5048544.

                  Koon HW, Su B, Xu C, Mussatto CC, Tran DH, Lee EC, Ortiz C, Wang J, Lee JE, Ho S, Chen X, Kelly CP, Pothoulakis C. Probiotic Saccharomyces boulardii CNCM I-745 prevents outbreak-associated Clostridium difficile-associated cecal inflammation in hamsters. American journal of physiology. Gastrointestinal and liver physiology. 2016 October 1;311(4):G610-G623. PubMed PMID: 27514478; PubMed Central PMCID: PMC5142203.

                  Hoang-Yen Tran D, Hoang-Ngoc Tran D, Mattai SA, Sallam T, Ortiz C, Lee EC, Robbins L, Ho S, Lee JE, Fisseha E, Shieh C, Sideri A, Shih DQ, Fleshner P, McGovern DP, Vu M, Hing TC, Bakirtzi K, Cheng M, Su B, Law I, Karagiannides I, Targan SR, Gallo RL, Li Z, Koon HW. Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. International journal of obesity (2005). 2016 September;40(9):1424-34. PubMed PMID: 27163748; PubMed Central PMCID: PMC5014693.

                  Million M, Larauche M. Stress, sex, and the enteric nervous system. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 September;28(9):1283-9. PubMed PMID: 27561694; PubMed Central PMCID: PMC5003424.

                  Padua D, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih D, Iliopoulos D, Pothoulakis C. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. American journal of physiology. Gastrointestinal and liver physiology. 2016 September 1;311(3):G446-57. PubMed PMID: 27492330; PubMed Central PMCID: PMC5076004.

                  Wang J, Sinnett-Smith J, Stevens JV, Young SH, Rozengurt E. Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD). The Journal of biological chemistry. 2016 August 19;291(34):17988-8005. PubMed PMID: 27369082; PubMed Central PMCID: PMC5016186.

                  Park SH, Videlock EJ, Shih W, Presson AP, Mayer EA, Chang L. Adverse childhood experiences are associated with irritable bowel syndrome and gastrointestinal symptom severity. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 August;28(8):1252-60. PubMed PMID: 27061107; PubMed Central PMCID: PMC4956522.

                  Antonios JP, Soto H, Everson RG, Orpilla J, Moughon D, Shin N, Sedighim S, Yong WH, Li G, Cloughesy TF, Liau LM, Prins RM. PD-1 blockade enhances the vaccination-induced immune response in glioma. JCI insight. 2016 July 7;1(10). PubMed PMID: 27453950; PubMed Central PMCID: PMC4951098.

                  Khalil HA, Lei NY, Brinkley G, Scott A, Wang J, Kar UK, Jabaji ZB, Lewis M, Martín MG, Dunn JC, Stelzner MG. A novel culture system for adult porcine intestinal crypts. Cell and tissue research. 2016 July;365(1):123-34. PubMed PMID: 26928041; PubMed Central PMCID: PMC4919165.

                  Videlock EJ, Shih W, Adeyemo M, Mahurkar-Joshi S, Presson AP, Polytarchou C, Alberto M, Iliopoulos D, Mayer EA, Chang L. The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression. Psychoneuroendocrinology. 2016 July;69:67-76. PubMed PMID: 27038676; PubMed Central PMCID: PMC4977028.

                  Kaji I, Akiba Y, Konno K, Watanabe M, Kimura S, Iwanaga T, Kuri A, Iwamoto K, Kuwahara A, Kaunitz JD. Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon. The Journal of physiology. 2016 June 15;594(12):3339-52. PubMed PMID: 26854275; PubMed Central PMCID: PMC4908031.

                  Holschneider DP, Guo Y, Mayer EA, Wang Z. Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats. Neurobiology of stress. 2016 June 1;3:8-22. PubMed PMID: 26751119; PubMed Central PMCID: PMC4700548.

                  Padua D, Vu JP, Germano PM, Pisegna JR. The Role of Neuropeptides in Mouse Models of Colitis. Journal of molecular neuroscience : MN. 2016 June;59(2):203-10. PubMed PMID: 26646243; PubMed Central PMCID: PMC4884658.

                  Scott A, Rouch JD, Jabaji Z, Khalil HA, Solorzano S, Lewis M, Martín MG, Stelzner MG, Dunn JC. Long-term renewable human intestinal epithelial stem cells as monolayers: A potential for clinical use. Journal of pediatric surgery. 2016 June;51(6):995-1000. PubMed PMID: 26995514; PubMed Central PMCID: PMC4921284.

                  Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. 2016 June;159(6):1520-1527. PubMed PMID: 26847803; PubMed Central PMCID: PMC4856542.

                  Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. American journal of physiology. Gastrointestinal and liver physiology. 2016 June 1;310(11):G1124-37. PubMed PMID: 27151939; PubMed Central PMCID: PMC5005285.

                  Yu J, Liu SH, Sanchez R, Nemunaitis J, Rozengurt E, Brunicardi FC. PDX1 associated therapy in translational medicine. Annals of translational medicine. 2016 June;4(11):214. PubMed PMID: 27386488; PubMed Central PMCID: PMC4916355.

                  Bakirtzi K, Law IK, Xue X, Iliopoulos D, Shah YM, Pothoulakis C. Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling. Journal of immunology (Baltimore, Md. : 1950). 2016 May 15;196(10):4311-21. PubMed PMID: 27076683; PubMed Central PMCID: PMC4868643.

                  Deriu E, Boxx GM, He X, Pan C, Benavidez SD, Cen L, Rozengurt N, Shi W, Cheng G. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS pathogens. 2016 May;12(5):e1005572. PubMed PMID: 27149619; PubMed Central PMCID: PMC4858270.

                  Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Molecular cancer research : MCR. 2016 May;14(5):437-47. PubMed PMID: 26979711; PubMed Central PMCID: PMC4867256.

                  Vorvis C, Koutsioumpa M, Iliopoulos D. Developments in miRNA gene signaling pathways in pancreatic cancer. Future oncology (London, England). 2016 May;12(9):1135-50. PubMed PMID: 26984178; PubMed Central PMCID: PMC5551925.

                  Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Science translational medicine. 2016 April 13;8(334):334ra54. PubMed PMID: 27075628; PubMed Central PMCID: PMC4934679.

                  Ackerman AL, Jellison FC, Lee UJ, Bradesi S, Rodríguez LV. The Glt1 glutamate receptor mediates the establishment and perpetuation of chronic visceral pain in an animal model of stress-induced bladder hyperalgesia. American journal of physiology. Renal physiology. 2016 April 1;310(7):F628-F636. PubMed PMID: 26697981; PubMed Central PMCID: PMC5504462.

                  Gupta A, Labus J, Kilpatrick LA, Bonyadi M, Ashe-McNalley C, Heendeniya N, Bradesi S, Chang L, Mayer EA. Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females. Brain structure & function. 2016 April;221(3):1667-79. PubMed PMID: 25630611; PubMed Central PMCID: PMC4573367.

                  Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly. International journal of antimicrobial agents. 2016 April;47(4):289-96. PubMed PMID: 27013001; PubMed Central PMCID: PMC4833571.

                  Wang J, Han L, Sinnett-Smith J, Han LL, Stevens JV, Rozengurt N, Young SH, Rozengurt E. Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552. American journal of physiology. Cell physiology. 2016 April 1;310(7):C542-57. PubMed PMID: 26739494; PubMed Central PMCID: PMC4824155.

                  Yuan PQ, Wu SV, Pothoulakis C, Taché Y. Urocortins and CRF receptor type 2 variants in the male rat colon: gene expression and regulation by endotoxin and anti-inflammatory effect. American journal of physiology. Gastrointestinal and liver physiology. 2016 March 15;310(6):G387-98. PubMed PMID: 26744472; PubMed Central PMCID: PMC4796293.

                  Hertzer KM, Xu M, Moro A, Dawson DW, Du L, Li G, Chang HH, Stark AP, Jung X, Hines OJ, Eibl G. Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer. Pancreas. 2016 March;45(3):458-65. PubMed PMID: 26495779; PubMed Central PMCID: PMC4854638.

                  Mahurkar S, Polytarchou C, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 March;28(3):410-22. PubMed PMID: 26670691; PubMed Central PMCID: PMC4760882.

                  Law IK, Jensen D, Bunnett NW, Pothoulakis C. Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin. Scientific reports. 2016 February 23;6:22195. PubMed PMID: 26902265; PubMed Central PMCID: PMC4763298.

                  Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi K, Dulai GS, Machicado GA. Natural history of definitive diverticular hemorrhage based on stigmata of recent hemorrhage and colonoscopic Doppler blood flow monitoring for risk stratification and definitive hemostasis. Gastrointestinal endoscopy. 2016 February;83(2):416-23. PubMed PMID: 26227931; PubMed Central PMCID: PMC4715947.

                  Walwyn WM, Chen W, Kim H, Minasyan A, Ennes HS, McRoberts JA, Marvizón JC. Sustained Suppression of Hyperalgesia during Latent Sensitization by μ-, δ-, and κ-opioid receptors and α2A Adrenergic Receptors: Role of Constitutive Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2016 January 6;36(1):204-21. PubMed PMID: 26740662; PubMed Central PMCID: PMC4701961.

                  Birtolo C, Go VL, Ptasznik A, Eibl G, Pandol SJ. Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas. 2016 January;45(1):21-31. PubMed PMID: 26658038; PubMed Central PMCID: PMC4859755.

                  Camus M, Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi KA, Machicado GA, Dulai GS, Jensen ME, Gornbein JA. Comparison of Three Risk Scores to Predict Outcomes of Severe Lower Gastrointestinal Bleeding. Journal of clinical gastroenterology. 2016 January;50(1):52-8. PubMed PMID: 25599218; PubMed Central PMCID: PMC4504830.

                  Hoffman JM, Baritaki S, Ruiz JJ, Sideri A, Pothoulakis C. Corticotropin-Releasing Hormone Receptor 2 Signaling Promotes Mucosal Repair Responses after Colitis. The American journal of pathology. 2016 January;186(1):134-44. PubMed PMID: 26597886; PubMed Central PMCID: PMC4714033.

                  Hong JY, Naliboff B, Labus JS, Gupta A, Kilpatrick LA, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Mayer EA. Altered brain responses in subjects with irritable bowel syndrome during cued and uncued pain expectation. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 January;28(1):127-38. PubMed PMID: 26526698; PubMed Central PMCID: PMC4943658.

                  Jarcho JM, Feier NA, Labus JS, Naliboff B, Smith SR, Hong JY, Colloca L, Tillisch K, Mandelkern MA, Mayer EA, London ED. Placebo analgesia: Self-report measures and preliminary evidence of cortical dopamine release associated with placebo response. NeuroImage. Clinical. 2016;10:107-14. PubMed PMID: 26759785; PubMed Central PMCID: PMC4683423.

                  Jensen DM, Ohning GV, Kovacs TO, Ghassemi KA, Jutabha R, Dulai GS, Machicado GA. Doppler endoscopic probe as a guide to risk stratification and definitive hemostasis of peptic ulcer bleeding. Gastrointestinal endoscopy. 2016 January;83(1):129-36. PubMed PMID: 26318834; PubMed Central PMCID: PMC4691549.

                  Labus JS, Naliboff B, Kilpatrick L, Liu C, Ashe-McNalley C, dos Santos IR, Alaverdyan M, Woodworth D, Gupta A, Ellingson BM, Tillisch K, Mayer EA. Pain and Interoception Imaging Network (PAIN): A multimodal, multisite, brain-imaging repository for chronic somatic and visceral pain disorders. NeuroImage. 2016 January 1;124(Pt B):1232-7. PubMed PMID: 25902408; PubMed Central PMCID: PMC4627849.

                  Latorre R, Huynh J, Mazzoni M, Gupta A, Bonora E, Clavenzani P, Chang L, Mayer EA, De Giorgio R, Sternini C. Expression of the Bitter Taste Receptor, T2R38, in Enteroendocrine Cells of the Colonic Mucosa of Overweight/Obese vs. Lean Subjects. PloS one. 2016;11(2):e0147468. PubMed PMID: 26866366; PubMed Central PMCID: PMC4750998.

                  Moussaoui N, Larauche M, Biraud M, Molet J, Million M, Mayer E, Taché Y. Limited Nesting Stress Alters Maternal Behavior and In Vivo Intestinal Permeability in Male Wistar Pup Rats. PloS one. 2016;11(5):e0155037. PubMed PMID: 27149676; PubMed Central PMCID: PMC4858303.

                  Rouch JD, Scott A, Lei NY, Solorzano-Vargas RS, Wang J, Hanson EM, Kobayashi M, Lewis M, Stelzner MG, Dunn JC, Eckmann L, Martín MG. Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. PloS one. 2016;11(1):e0148216. PubMed PMID: 26820624; PubMed Central PMCID: PMC4731053.

                  Zhou G, Yu J, Wang A, Liu SH, Sinnett-Smith J, Wu J, Sanchez R, Nemunaitis J, Ricordi C, Rozengurt E, Brunicardi FC. Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma. Current molecular medicine. 2016;16(1):83-90. PubMed PMID: 26695692; PubMed Central PMCID: PMC4994969.

                  Vuong HE, Hardi CN, Barnes S, Brecha NC. Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 December 2;35(48):15955-70. PubMed PMID: 26631476; PubMed Central PMCID: PMC4666919.

                  Kilpatrick LA, Istrin JJ, Gupta A, Naliboff BD, Tillisch K, Labus JS, Mayer EA. Sex commonalities and differences in the relationship between resilient personality and the intrinsic connectivity of the salience and default mode networks. Biological psychology. 2015 December;112:107-15. PubMed PMID: 26440126; PubMed Central PMCID: PMC5012423.

                  Phan J, Benhammou JN, Pisegna JR. Gastric Hypersecretory States: Investigation and Management. Current treatment options in gastroenterology. 2015 December;13(4):386-97. PubMed PMID: 26342486; PubMed Central PMCID: PMC4633316.

                  Stark AP, Chang HH, Jung X, Moro A, Hertzer K, Xu M, Schmidt A, Hines OJ, Eibl G. E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice. Surgery. 2015 December;158(6):1564-72. PubMed PMID: 26297056; PubMed Central PMCID: PMC4637247.

                  Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of experimental medicine. 2015 November 16;212(12):2147-63. PubMed PMID: 26552708; PubMed Central PMCID: PMC4647265.

                  Chang HH, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G. Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1. American journal of physiology. Cell physiology. 2015 November 15;309(10):C639-49. PubMed PMID: 26310818; PubMed Central PMCID: PMC4652080.

                  Vu JP, Goyal D, Luong L, Oh S, Sandhu R, Norris J, Parsons W, Pisegna JR, Germano PM. PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin. American journal of physiology. Gastrointestinal and liver physiology. 2015 November 15;309(10):G816-25. PubMed PMID: 26336928; PubMed Central PMCID: PMC4652141.

                  Young SH, Rey O, Rozengurt E. Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: Impact of the highly conservative mutation Ser170Thr. Biochemical and biophysical research communications. 2015 November 6;467(1):1-6. PubMed PMID: 26431875; PubMed Central PMCID: PMC4613767.

                  Rodriguez JA, Huerta-Yepez S, Law IK, Baay-Guzman GJ, Tirado-Rodriguez B, Hoffman JM, Iliopoulos D, Hommes DW, Verspaget HW, Chang L, Pothoulakis C, Baritaki S. Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling. Cellular and molecular gastroenterology and hepatology. 2015 November 1;1(6):610-630. PubMed PMID: 26495412; PubMed Central PMCID: PMC4610032.

                  Vuong HE, Pérez de Sevilla Müller L, Hardi CN, McMahon DG, Brecha NC. Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines. Neuroscience. 2015 October 29;307:319-37. PubMed PMID: 26335381; PubMed Central PMCID: PMC4603663.

                  Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D. MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice. Gastroenterology. 2015 October;149(4):981-92.e11. PubMed PMID: 26055138; PubMed Central PMCID: PMC4584179.

                  Fang K, Sideri A, Law IK, Bakirtzi K, Polytarchou C, Iliopoulos D, Pothoulakis C. Identification of a novel substance P (SP)-neurokinin-1 receptor (NK-1R) microRNA-221-5p inflammatory network in human colonic epithelial cells. Cellular and molecular gastroenterology and hepatology. 2015 September 1;1(5):503-515. PubMed PMID: 26645045; PubMed Central PMCID: PMC4669978.

                  Hubbard CS, Hong J, Jiang Z, Ebrat B, Suyenobu B, Smith S, Heendeniya N, Naliboff BD, Tillisch K, Mayer EA, Labus JS. Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 September;27(9):1282-94. PubMed PMID: 26087779; PubMed Central PMCID: PMC4550526.

                  Cherukuri DP, Deignan JL, Das K, Grody WW, Herschman H. Instability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma. Molecular oncology. 2015 August;9(7):1252-8. PubMed PMID: 25817443; PubMed Central PMCID: PMC4523444.

                  Irimia A, Labus JS, Torgerson CM, Van Horn JD, Mayer EA. Altered viscerotopic cortical innervation in patients with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 August;27(8):1075-81. PubMed PMID: 25952540; PubMed Central PMCID: PMC4520752.

                  Kaunitz JD. The Discovery of PCR: ProCuRement of Divine Power. Digestive diseases and sciences. 2015 August;60(8):2230-1. PubMed PMID: 26077976; PubMed Central PMCID: PMC4501591.

                  Kobayashi M, Lei NY, Wang Q, Wu BM, Dunn JC. Orthogonally oriented scaffolds with aligned fibers for engineering intestinal smooth muscle. Biomaterials. 2015 August;61:75-84. PubMed PMID: 26001072; PubMed Central PMCID: PMC4464968.

                  Labus JS, Van Horn JD, Gupta A, Alaverdyan M, Torgerson C, Ashe-McNalley C, Irimia A, Hong JY, Naliboff B, Tillisch K, Mayer EA. Multivariate morphological brain signatures predict patients with chronic abdominal pain from healthy control subjects. Pain. 2015 August;156(8):1545-54. PubMed PMID: 25906347; PubMed Central PMCID: PMC4504800.

                  O'Mahony F, Wroblewski K, O'Byrne SM, Jiang H, Clerkin K, Benhammou J, Blaner WS, Beaven SW. Liver X receptors balance lipid stores in hepatic stellate cells through Rab18, a retinoid responsive lipid droplet protein. Hepatology (Baltimore, Md.). 2015 August;62(2):615-26. PubMed PMID: 25482505; PubMed Central PMCID: PMC4458237.

                  Tuominen I, Beaven SW. Intestinal farnesoid X receptor puts a fresh coat of wax on fatty liver. Hepatology (Baltimore, Md.). 2015 August;62(2):646-8. PubMed PMID: 25998695; PubMed Central PMCID: PMC4523235.

                  Law IK, Bakirtzi K, Polytarchou C, Oikonomopoulos A, Hommes D, Iliopoulos D, Pothoulakis C. Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis. Gut. 2015 July;64(7):1095-104. PubMed PMID: 25112884; PubMed Central PMCID: PMC4422787.

                  Lugea A, Waldron RT, Pandol SJ. Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2015 July;15(4 Suppl):S1-5. PubMed PMID: 25736240; PubMed Central PMCID: PMC4515411.

                  Stengel A, Karasawa H, Taché Y. The role of brain somatostatin receptor 2 in the regulation of feeding and drinking behavior. Hormones and behavior. 2015 July;73:15-22. PubMed PMID: 26026616; PubMed Central PMCID: PMC4546908.

                  Sanmiguel C, Gupta A, Mayer EA. Gut Microbiome and Obesity: A Plausible Explanation for Obesity. Current obesity reports. 2015 June;4(2):250-61. PubMed PMID: 26029487; PubMed Central PMCID: PMC4443745.

                  Vu JP, Larauche M, Flores M, Luong L, Norris J, Oh S, Liang LJ, Waschek J, Pisegna JR, Germano PM. Regulation of Appetite, Body Composition, and Metabolic Hormones by Vasoactive Intestinal Polypeptide (VIP). Journal of molecular neuroscience : MN. 2015 June;56(2):377-87. PubMed PMID: 25904310; PubMed Central PMCID: PMC4458420.

                  Gupta A, Rapkin AJ, Gill Z, Kilpatrick L, Fling C, Stains J, Masghati S, Tillisch K, Mayer EA, Labus JS. Disease-related differences in resting-state networks: a comparison between localized provoked vulvodynia, irritable bowel syndrome, and healthy control subjects. Pain. 2015 May;156(5):809-19. PubMed PMID: 25735001; PubMed Central PMCID: PMC4402252.

                  Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D. A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. Inflammatory bowel diseases. 2015 May;21(5):996-1005. PubMed PMID: 25738378; PubMed Central PMCID: PMC4402238.

                  Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JC, Martin MG, Lagasse E, Zhang L, Yu J. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Scientific reports. 2015 April 10;5:8566. PubMed PMID: 25858503; PubMed Central PMCID: PMC4392360.

                  Wu JX, Liu SH, Nemunaitis JJ, Brunicardi FC. Liposomal insulin promoter-thymidine kinase gene therapy followed by ganciclovir effectively ablates human pancreatic cancer in mice. Cancer letters. 2015 April 10;359(2):206-10. PubMed PMID: 25596375; PubMed Central PMCID: PMC4336837.

                  Akiba Y, Kaunitz JD, Million M. Peripheral corticotropin-releasing factor receptor type 2 activation increases colonic blood flow through nitric oxide pathway in rats. Digestive diseases and sciences. 2015 April;60(4):858-67. PubMed PMID: 25701320; PubMed Central PMCID: PMC4501405.

                  Anselmi L, Huynh J, Duraffourd C, Jaramillo I, Vegezzi G, Saccani F, Boschetti E, Brecha NC, De Giorgio R, Sternini C. Activation of μ opioid receptors modulates inflammation in acute experimental colitis. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 April;27(4):509-23. PubMed PMID: 25690069; PubMed Central PMCID: PMC4405133.

                  Liu Z, Sun F, Braun J, McGovern DP, Piantadosi S. Multilevel regularized regression for simultaneous taxa selection and network construction with metagenomic count data. Bioinformatics (Oxford, England). 2015 April 1;31(7):1067-74. PubMed PMID: 25416747; PubMed Central PMCID: PMC4382903.

                  Marvizon JC, Walwyn W, Minasyan A, Chen W, Taylor BK. Latent sensitization: a model for stress-sensitive chronic pain. Current protocols in neuroscience. 2015 April 1;71:9.50.1-14. PubMed PMID: 25829356; PubMed Central PMCID: PMC4532319.

                  Mayer EA, Gupta A, Kilpatrick LA, Hong JY. Imaging brain mechanisms in chronic visceral pain. Pain. 2015 April;156 Suppl 1:S50-63. PubMed PMID: 25789437; PubMed Central PMCID: PMC4428597.

                  Sideri A, Stavrakis D, Bowe C, Shih DQ, Fleshner P, Arsenescu V, Arsenescu R, Turner JR, Pothoulakis C, Karagiannides I. Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1. American journal of physiology. Gastrointestinal and liver physiology. 2015 April 1;308(7):G591-604. PubMed PMID: 25591865; PubMed Central PMCID: PMC4385897.

                  Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2. Molecular cancer therapeutics. 2015 April;14(4):1014-23. PubMed PMID: 25673820; PubMed Central PMCID: PMC4394038.

                  Tarling EJ, Ahn H, de Aguiar Vallim TQ. The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2. Arteriosclerosis, thrombosis, and vascular biology. 2015 April;35(4):787-95. PubMed PMID: 25593129; PubMed Central PMCID: PMC4376635.

                  Gukovsky I, Gukovskaya AS. Impaired autophagy triggers chronic pancreatitis: lessons from pancreas-specific atg5 knockout mice. Gastroenterology. 2015 March;148(3):501-5. PubMed PMID: 25613315; PubMed Central PMCID: PMC4443443.

                  Liu Y, Ji H, Zhang Y, Shen X, Gao F, He X, Li GA, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury. Journal of hepatology. 2015 March;62(3):563-72. PubMed PMID: 25450716; PubMed Central PMCID: PMC4336640.

                  Sakanaka T, Inoue T, Yorifuji N, Iguchi M, Fujiwara K, Narabayashi K, Kakimoto K, Nouda S, Okada T, Kuramoto T, Ishida K, Abe Y, Takeuchi T, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. The effects of a TGR5 agonist and a dipeptidyl peptidase IV inhibitor on dextran sulfate sodium-induced colitis in mice. Journal of gastroenterology and hepatology. 2015 March;30 Suppl 1:60-5. PubMed PMID: 25827806; PubMed Central PMCID: PMC4874188.

                  Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. The Journal of biological chemistry. 2015 February 27;290(9):5566-81. PubMed PMID: 25468909; PubMed Central PMCID: PMC4342471.

                  Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. Septin dynamics are essential for exocytosis. The Journal of biological chemistry. 2015 February 27;290(9):5280-97. PubMed PMID: 25575596; PubMed Central PMCID: PMC4342448.

                  Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell metabolism. 2015 February 3;21(2):334-46. PubMed PMID: 25651185; PubMed Central PMCID: PMC4349439.

                  de Aguiar Vallim TQ, Tarling EJ, Ahn H, Hagey LR, Romanoski CE, Lee RG, Graham MJ, Motohashi H, Yamamoto M, Edwards PA. MAFG is a transcriptional repressor of bile acid synthesis and metabolism. Cell metabolism. 2015 February 3;21(2):298-310. PubMed PMID: 25651182; PubMed Central PMCID: PMC4317590.

                  Bromley EG, May FP, Federer L, Spiegel BM, van Oijen MG. Explaining persistent under-use of colonoscopic cancer screening in African Americans: a systematic review. Preventive medicine. 2015 February;71:40-8. PubMed PMID: 25481094; PubMed Central PMCID: PMC4329030.

                  Kaji I, Iwanaga T, Watanabe M, Guth PH, Engel E, Kaunitz JD, Akiba Y. SCFA transport in rat duodenum. American journal of physiology. Gastrointestinal and liver physiology. 2015 February 1;308(3):G188-97. PubMed PMID: 25394661; PubMed Central PMCID: PMC4312951.

                  Nguyen AH, Toste PA, Farrell JJ, Clerkin BM, Williams J, Muthusamy VR, Watson RR, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Current recommendations for surveillance and surgery of intraductal papillary mucinous neoplasms may overlook some patients with cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2015 February;19(2):258-65. PubMed PMID: 25373706; PubMed Central PMCID: PMC4305480.

                  Tan YV, Abad C, Wang Y, Lopez R, Waschek J. VPAC2 (vasoactive intestinal peptide receptor type 2) receptor deficient mice develop exacerbated experimental autoimmune encephalomyelitis with increased Th1/Th17 and reduced Th2/Treg responses. Brain, behavior, and immunity. 2015 February;44:167-175. PubMed PMID: 25305591; PubMed Central PMCID: PMC4275378.

                  Taché Y, Million M. Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia. Journal of neurogastroenterology and motility. 2015 January 31;21(1):8-24. PubMed PMID: 25611064; PubMed Central PMCID: PMC4288101.

                  Coveleskie K, Gupta A, Kilpatrick LA, Mayer ED, Ashe-McNalley C, Stains J, Labus JS, Mayer EA. Altered functional connectivity within the central reward network in overweight and obese women. Nutrition & diabetes. 2015 January 19;5:e148. PubMed PMID: 25599560; PubMed Central PMCID: PMC4314578.

                  Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology. 2015 January 15;475:46-55. PubMed PMID: 25462345; PubMed Central PMCID: PMC4284078.

                  Abad C, Cheung-Lau G, Coûté-Monvoisin AC, Waschek JA. Vasoactive intestinal peptide-deficient mice exhibit reduced pathology in trinitrobenzene sulfonic acid-induced colitis. Neuroimmunomodulation. 2015;22(3):203-12. PubMed PMID: 25301381; PubMed Central PMCID: PMC4297532.

                  Bradesi S, Karagiannides I, Bakirtzi K, Joshi SM, Koukos G, Iliopoulos D, Pothoulakis C, Mayer EA. Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat. PloS one. 2015;10(7):e0130938. PubMed PMID: 26222740; PubMed Central PMCID: PMC4519289.

                  Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. Journal of Alzheimer's disease : JAD. 2015;43(3):967-76. PubMed PMID: 25125464; PubMed Central PMCID: PMC4258165.

                  Chen R, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM, Maitra A, Brentnall TA. Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. Laboratory investigation; a journal of technical methods and pathology. 2015 January;95(1):43-55. PubMed PMID: 25347153; PubMed Central PMCID: PMC4281293.

                  Cheng M, Ho S, Yoo JH, Tran DH, Bakirtzi K, Su B, Tran DH, Kubota Y, Ichikawa R, Koon HW. Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts. Clinical and experimental gastroenterology. 2015;8:13-29. PubMed PMID: 25565877; PubMed Central PMCID: PMC4274046.

                  Gupta A, Mayer EA, Sanmiguel CP, Van Horn JD, Woodworth D, Ellingson BM, Fling C, Love A, Tillisch K, Labus JS. Patterns of brain structural connectivity differentiate normal weight from overweight subjects. NeuroImage. Clinical. 2015;7:506-17. PubMed PMID: 25737959; PubMed Central PMCID: PMC4338207.

                  Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 January 1;21(1):157-65. PubMed PMID: 25348515; PubMed Central PMCID: PMC4286535.

                  Khalil HA, Lei NY, Nie W, Lewis MS, Stelzner MG, Martín MG, Dunn JC, Yoo J. Primary Myofibroblasts Maintain Short-Term Viability following Submucosal Injection in Syngeneic, Immune-Competent Mice Utilizing Murine Colonoscopy. PloS one. 2015;10(5):e0127258. PubMed PMID: 26016485; PubMed Central PMCID: PMC4445916.

                  Kutch JJ, Yani MS, Asavasopon S, Kirages DJ, Rana M, Cosand L, Labus JS, Kilpatrick LA, Ashe-McNalley C, Farmer MA, Johnson KA, Ness TJ, Deutsch G, Harris RE, Apkarian AV, Clauw DJ, Mackey SC, Mullins C, Mayer EA. Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study. NeuroImage. Clinical. 2015;8:493-502. PubMed PMID: 26106574; PubMed Central PMCID: PMC4474411.

                  Law IK, Pothoulakis C. MicroRNA-133α regulates neurotensin-associated colonic inflammation in colonic epithelial cells and experimental colitis. RNA & disease (Houston, Tex.). 2015;2(1). PubMed PMID: 26005712; PubMed Central PMCID: PMC4441413.

                  Li Y, Go VL, Sarkar FH. The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome. Pancreas. 2015 January;44(1):1-10. PubMed PMID: 25493373; PubMed Central PMCID: PMC4264839.

                  Martinez L, Ermolova NV, Ishikawa TO, Stout DB, Herschman HR, Spencer MJ. A reporter mouse for optical imaging of inflammation in mdx muscles. Skeletal muscle. 2015;5:15. PubMed PMID: 25949789; PubMed Central PMCID: PMC4422315.

                  Marzagalli R, Scuderi S, Drago F, Waschek JA, Castorina A. Emerging Role of PACAP as a New Potential Therapeutic Target in Major Diabetes Complications. International journal of endocrinology. 2015;2015:160928. PubMed PMID: 26074958; PubMed Central PMCID: PMC4446501.

                  McGowan I, Anton PA, Elliott J, Cranston RD, Duffill K, Althouse AD, Hawkins KL, De Rosa SC. Exploring the feasibility of multi-site flow cytometric processing of gut associated lymphoid tissue with centralized data analysis for multi-site clinical trials. PloS one. 2015;10(5):e0126454. PubMed PMID: 26010577; PubMed Central PMCID: PMC4444258.

                  Mulak A, Larauche M, Biraud M, Million M, Rivier J, Taché Y. Selective agonists of somatostatin receptor subtype 1 or 2 injected peripherally induce antihyperalgesic effect in two models of visceral hypersensitivity in mice. Peptides. 2015 January;63:71-80. PubMed PMID: 25451334; PubMed Central PMCID: PMC4385413.

                  Orand A, Gupta A, Shih W, Presson AP, Hammer C, Niesler B, Heendeniya N, Mayer EA, Chang L. Catecholaminergic Gene Polymorphisms Are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome. PloS one. 2015;10(8):e0135910. PubMed PMID: 26288143; PubMed Central PMCID: PMC4546052.

                  Taché Y. Corticotrophin-releasing factor 1 activation in the central amygdale and visceral hyperalgesia. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 January;27(1):1-6. PubMed PMID: 25557223; PubMed Central PMCID: PMC4389773.

                  Wang L, Mogami S, Yakabi S, Karasawa H, Yamada C, Yakabi K, Hattori T, Taché Y. Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito. PloS one. 2015;10(9):e0139325. PubMed PMID: 26421719; PubMed Central PMCID: PMC4589401.

                  Wang Y, Yan C, Liu L, Wang W, Du H, Fan W, Lutfy K, Jiang M, Friedman TC, Liu Y. 11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue. American journal of physiology. Endocrinology and metabolism. 2015 January 1;308(1):E84-95. PubMed PMID: 25389364; PubMed Central PMCID: PMC4281684.

                  Yoo JH, Ho S, Tran DH, Cheng M, Bakirtzi K, Kukota Y, Ichikawa R, Su B, Tran DH, Hing TC, Chang I, Shih DQ, Issacson RE, Gallo RL, Fiocchi C, Pothoulakis C, Koon HW. Anti-fibrogenic effects of the anti-microbial peptide cathelicidin in murine colitis-associated fibrosis. Cellular and molecular gastroenterology and hepatology. 2015 January;1(1):55-74.e1. PubMed PMID: 25729764; PubMed Central PMCID: PMC4338438.

                  Zhu J, Lu T, Yue S, Shen X, Gao F, Busuttil RW, Kupiec-Weglinski JW, Xia Q, Zhai Y. Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation. Transplantation. 2015 January;99(1):48-55. PubMed PMID: 25340604; PubMed Central PMCID: PMC4272660.

                  Akiba Y, Kaunitz JD. Prostaglandin pathways in duodenal chemosensing. Journal of gastroenterology and hepatology. 2014 December;29 Suppl 4:93-8. PubMed PMID: 25521740; PubMed Central PMCID: PMC4451058.

                  Bagarinao E, Johnson KA, Martucci KT, Ichesco E, Farmer MA, Labus J, Ness TJ, Harris R, Deutsch G, Apkarian AV, Mayer EA, Clauw DJ, Mackey S. Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network study. Pain. 2014 December;155(12):2502-9. PubMed PMID: 25242566; PubMed Central PMCID: PMC4504202.

                  Buzzanco A, Gomez A, Rodriguez E, French BA, Tillman BA, Chang S, Ganapathy E, Junrungsee S, Zarrinpar A, Agopian VG, Naini BV, French SW Jr, French SW Sr. Digital quantitation of HCC-associated stem cell markers and protein quality control factors using tissue arrays of human liver sections. Experimental and molecular pathology. 2014 December;97(3):399-410. PubMed PMID: 25218810; PubMed Central PMCID: PMC4262606.

                  Donahue TR, Nguyen AH, Moughan J, Li L, Tatishchev S, Toste P, Farrell JJ. Stromal microRNA-21 levels predict response to 5-fluorouracil in patients with pancreatic cancer. Journal of surgical oncology. 2014 December;110(8):952-9. PubMed PMID: 25132574; PubMed Central PMCID: PMC4232442.

                  Ji H, Liu Y, Zhang Y, Shen XD, Gao F, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. T-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury. Hepatology (Baltimore, Md.). 2014 December;60(6):2052-2064. PubMed PMID: 25066922; PubMed Central PMCID: PMC4396987.

                  Karasawa H, Pietra C, Giuliano C, Garcia-Rubio S, Xu X, Yakabi S, Taché Y, Wang L. New ghrelin agonist, HM01 alleviates constipation and L-dopa-delayed gastric emptying in 6-hydroxydopamine rat model of Parkinson's disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 December;26(12):1771-82. PubMed PMID: 25327342; PubMed Central PMCID: PMC4457321.

                  Stengel A, Taché Y. Brain peptides and the modulation of postoperative gastric ileus. Current opinion in pharmacology. 2014 December;19:31-7. PubMed PMID: 24999843; PubMed Central PMCID: PMC4254047.

                  Wagner JP, Sullins VF, Dunn JC. Skin-derived precursors generate enteric-type neurons in aganglionic jejunum. Journal of pediatric surgery. 2014 December;49(12):1809-14. PubMed PMID: 25487489; PubMed Central PMCID: PMC4261145.

                  Wagner JP, Sullins VF, Khalil HA, Dunn JC. A durable model of Hirschsprung's colon. Journal of pediatric surgery. 2014 December;49(12):1804-8. PubMed PMID: 25487488; PubMed Central PMCID: PMC4261142.

                  Hong C, Marshall SM, McDaniel AL, Graham M, Layne JD, Cai L, Scotti E, Boyadjian R, Kim J, Chamberlain BT, Tangirala RK, Jung ME, Fong L, Lee R, Young SG, Temel RE, Tontonoz P. The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice. Cell metabolism. 2014 November 4;20(5):910-8. PubMed PMID: 25440061; PubMed Central PMCID: PMC4261644.

                  Tong M, Jacobs JP, McHardy IH, Braun J. Sampling of intestinal microbiota and targeted amplification of bacterial 16S rRNA genes for microbial ecologic analysis. Current protocols in immunology. 2014 November 3;107:7.41.1-11. PubMed PMID: 25367129; PubMed Central PMCID: PMC4457454.

                  Balaji K, French CT, Miller JF, Colicelli J. The RAB5-GEF function of RIN1 regulates multiple steps during Listeria monocytogenes infection. Traffic (Copenhagen, Denmark). 2014 November;15(11):1206-18. PubMed PMID: 25082076; PubMed Central PMCID: PMC4282165.

                  Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR. Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. Molecular cancer research : MCR. 2014 November;12(11):1677-88. PubMed PMID: 25063587; PubMed Central PMCID: PMC4233191.

                  Rozengurt E, Soares HP, Sinnet-Smith J. Suppression of feedback loops mediated by PI3K/mTOR induces multiple overactivation of compensatory pathways: an unintended consequence leading to drug resistance. Molecular cancer therapeutics. 2014 November;13(11):2477-88. PubMed PMID: 25323681; PubMed Central PMCID: PMC4222988.

                  Shih DQ, Zheng L, Zhang X, Zhang H, Kanazawa Y, Ichikawa R, Wallace KL, Chen J, Pothoulakis C, Koon HW, Targan SR. Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis. Mucosal immunology. 2014 November;7(6):1492-503. PubMed PMID: 24850426; PubMed Central PMCID: PMC4205266.

                  Spiegel BM, Hays RD, Bolus R, Melmed GY, Chang L, Whitman C, Khanna PP, Paz SH, Hays T, Reise S, Khanna D. Development of the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) gastrointestinal symptom scales. The American journal of gastroenterology. 2014 November;109(11):1804-14. PubMed PMID: 25199473; PubMed Central PMCID: PMC4285435.

                  Hong JY, Kilpatrick LA, Labus JS, Gupta A, Katibian D, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Naliboff B, Mayer EA. Sex and disease-related alterations of anterior insula functional connectivity in chronic abdominal pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 October 22;34(43):14252-9. PubMed PMID: 25339739; PubMed Central PMCID: PMC4205551.

                  Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Molecular cancer therapeutics. 2014 October;13(10):2303-14. PubMed PMID: 25082960; PubMed Central PMCID: PMC4188417.

                  Itoh Y, Arnold AP. X chromosome regulation of autosomal gene expression in bovine blastocysts. Chromosoma. 2014 October;123(5):481-9. PubMed PMID: 24817096; PubMed Central PMCID: PMC4170013.

                  Ruegger PM, Clark RT, Weger JR, Braun J, Borneman J. Improved resolution of bacteria by high throughput sequence analysis of the rRNA internal transcribed spacer. Journal of microbiological methods. 2014 October;105:82-7. PubMed PMID: 25034229; PubMed Central PMCID: PMC4160368.

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                  Ming M, Sinnett-Smith J, Wang J, Soares HP, Young SH, Eibl G, Rozengurt E. Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. PloS one. 2014;9(12):e114573. PubMed PMID: 25493642; PubMed Central PMCID: PMC4262417.

                  Richardson-Harman N, Hendrix CW, Bumpus NN, Mauck C, Cranston RD, Yang K, Elliott J, Tanner K, McGowan I, Kashuba A, Anton PA. Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study. PloS one. 2014;9(10):e111507. PubMed PMID: 25350130; PubMed Central PMCID: PMC4211741.

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                  Vu JP, Million M, Larauche M, Luong L, Norris J, Waschek JA, Pothoulakis C, Pisegna JR, Germano PM. Inhibition of vasoactive intestinal polypeptide (VIP) induces resistance to dextran sodium sulfate (DSS)-induced colitis in mice. Journal of molecular neuroscience : MN. 2014 January;52(1):37-47. PubMed PMID: 24395090; PubMed Central PMCID: PMC4114158.

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                  Ke B, Shen XD, Zhang Y, Ji H, Gao F, Yue S, Kamo N, Zhai Y, Yamamoto M, Busuttil RW, Kupiec-Weglinski JW. KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants. Journal of hepatology. 2013 December;59(6):1200-7. PubMed PMID: 23867319; PubMed Central PMCID: PMC4524560.

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                  Sinnett-Smith J, Kisfalvi K, Kui R, Rozengurt E. Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK. Biochemical and biophysical research communications. 2013 January 4;430(1):352-7. PubMed PMID: 23159620; PubMed Central PMCID: PMC3545113.

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                  Rozengurt E, Sinnett-Smith J, Kisfalvi K. Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2010 May 1;16(9):2505-11. PubMed PMID: 20388847; PubMed Central PMCID: PMC2862089.

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                  Hoang-Yen Tran D, Hoang-Ngoc Tran D, Mattai SA, Sallam T, Ortiz C, Lee EC, Robbins L, Ho S, Lee JE, Fisseha E, Shieh C, Sideri A, Shih DQ, Fleshner P, McGovern DP, Vu M, Hing TC, Bakirtzi K, Cheng M, Su B, Law I, Karagiannides I, Targan SR, Gallo RL, Li Z, Koon HW. Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. International journal of obesity (2005). 2016 September;40(9):1424-34. PubMed PMID: 27163748; PubMed Central PMCID: PMC5014693.

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                  Padua D, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih D, Iliopoulos D, Pothoulakis C. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. American journal of physiology. Gastrointestinal and liver physiology. 2016 September 1;311(3):G446-57. PubMed PMID: 27492330; PubMed Central PMCID: PMC5076004.

                  Wang J, Sinnett-Smith J, Stevens JV, Young SH, Rozengurt E. Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD). The Journal of biological chemistry. 2016 August 19;291(34):17988-8005. PubMed PMID: 27369082; PubMed Central PMCID: PMC5016186.

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                  Antonios JP, Soto H, Everson RG, Orpilla J, Moughon D, Shin N, Sedighim S, Yong WH, Li G, Cloughesy TF, Liau LM, Prins RM. PD-1 blockade enhances the vaccination-induced immune response in glioma. JCI insight. 2016 July 7;1(10). PubMed PMID: 27453950; PubMed Central PMCID: PMC4951098.

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                  Videlock EJ, Shih W, Adeyemo M, Mahurkar-Joshi S, Presson AP, Polytarchou C, Alberto M, Iliopoulos D, Mayer EA, Chang L. The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression. Psychoneuroendocrinology. 2016 July;69:67-76. PubMed PMID: 27038676; PubMed Central PMCID: PMC4977028.

                  Kaji I, Akiba Y, Konno K, Watanabe M, Kimura S, Iwanaga T, Kuri A, Iwamoto K, Kuwahara A, Kaunitz JD. Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon. The Journal of physiology. 2016 June 15;594(12):3339-52. PubMed PMID: 26854275; PubMed Central PMCID: PMC4908031.

                  Holschneider DP, Guo Y, Mayer EA, Wang Z. Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats. Neurobiology of stress. 2016 June 1;3:8-22. PubMed PMID: 26751119; PubMed Central PMCID: PMC4700548.

                  Padua D, Vu JP, Germano PM, Pisegna JR. The Role of Neuropeptides in Mouse Models of Colitis. Journal of molecular neuroscience : MN. 2016 June;59(2):203-10. PubMed PMID: 26646243; PubMed Central PMCID: PMC4884658.

                  Scott A, Rouch JD, Jabaji Z, Khalil HA, Solorzano S, Lewis M, Martín MG, Stelzner MG, Dunn JC. Long-term renewable human intestinal epithelial stem cells as monolayers: A potential for clinical use. Journal of pediatric surgery. 2016 June;51(6):995-1000. PubMed PMID: 26995514; PubMed Central PMCID: PMC4921284.

                  Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. 2016 June;159(6):1520-1527. PubMed PMID: 26847803; PubMed Central PMCID: PMC4856542.

                  Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. American journal of physiology. Gastrointestinal and liver physiology. 2016 June 1;310(11):G1124-37. PubMed PMID: 27151939; PubMed Central PMCID: PMC5005285.

                  Yu J, Liu SH, Sanchez R, Nemunaitis J, Rozengurt E, Brunicardi FC. PDX1 associated therapy in translational medicine. Annals of translational medicine. 2016 June;4(11):214. PubMed PMID: 27386488; PubMed Central PMCID: PMC4916355.

                  Bakirtzi K, Law IK, Xue X, Iliopoulos D, Shah YM, Pothoulakis C. Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling. Journal of immunology (Baltimore, Md. : 1950). 2016 May 15;196(10):4311-21. PubMed PMID: 27076683; PubMed Central PMCID: PMC4868643.

                  Deriu E, Boxx GM, He X, Pan C, Benavidez SD, Cen L, Rozengurt N, Shi W, Cheng G. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS pathogens. 2016 May;12(5):e1005572. PubMed PMID: 27149619; PubMed Central PMCID: PMC4858270.

                  Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Molecular cancer research : MCR. 2016 May;14(5):437-47. PubMed PMID: 26979711; PubMed Central PMCID: PMC4867256.

                  Vorvis C, Koutsioumpa M, Iliopoulos D. Developments in miRNA gene signaling pathways in pancreatic cancer. Future oncology (London, England). 2016 May;12(9):1135-50. PubMed PMID: 26984178; PubMed Central PMCID: PMC5551925.

                  Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Science translational medicine. 2016 April 13;8(334):334ra54. PubMed PMID: 27075628; PubMed Central PMCID: PMC4934679.

                  Ackerman AL, Jellison FC, Lee UJ, Bradesi S, Rodríguez LV. The Glt1 glutamate receptor mediates the establishment and perpetuation of chronic visceral pain in an animal model of stress-induced bladder hyperalgesia. American journal of physiology. Renal physiology. 2016 April 1;310(7):F628-F636. PubMed PMID: 26697981; PubMed Central PMCID: PMC5504462.

                  Gupta A, Labus J, Kilpatrick LA, Bonyadi M, Ashe-McNalley C, Heendeniya N, Bradesi S, Chang L, Mayer EA. Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females. Brain structure & function. 2016 April;221(3):1667-79. PubMed PMID: 25630611; PubMed Central PMCID: PMC4573367.

                  Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly. International journal of antimicrobial agents. 2016 April;47(4):289-96. PubMed PMID: 27013001; PubMed Central PMCID: PMC4833571.

                  Wang J, Han L, Sinnett-Smith J, Han LL, Stevens JV, Rozengurt N, Young SH, Rozengurt E. Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552. American journal of physiology. Cell physiology. 2016 April 1;310(7):C542-57. PubMed PMID: 26739494; PubMed Central PMCID: PMC4824155.

                  Yuan PQ, Wu SV, Pothoulakis C, Taché Y. Urocortins and CRF receptor type 2 variants in the male rat colon: gene expression and regulation by endotoxin and anti-inflammatory effect. American journal of physiology. Gastrointestinal and liver physiology. 2016 March 15;310(6):G387-98. PubMed PMID: 26744472; PubMed Central PMCID: PMC4796293.

                  Hertzer KM, Xu M, Moro A, Dawson DW, Du L, Li G, Chang HH, Stark AP, Jung X, Hines OJ, Eibl G. Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer. Pancreas. 2016 March;45(3):458-65. PubMed PMID: 26495779; PubMed Central PMCID: PMC4854638.

                  Mahurkar S, Polytarchou C, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 March;28(3):410-22. PubMed PMID: 26670691; PubMed Central PMCID: PMC4760882.

                  Law IK, Jensen D, Bunnett NW, Pothoulakis C. Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin. Scientific reports. 2016 February 23;6:22195. PubMed PMID: 26902265; PubMed Central PMCID: PMC4763298.

                  Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi K, Dulai GS, Machicado GA. Natural history of definitive diverticular hemorrhage based on stigmata of recent hemorrhage and colonoscopic Doppler blood flow monitoring for risk stratification and definitive hemostasis. Gastrointestinal endoscopy. 2016 February;83(2):416-23. PubMed PMID: 26227931; PubMed Central PMCID: PMC4715947.

                  Walwyn WM, Chen W, Kim H, Minasyan A, Ennes HS, McRoberts JA, Marvizón JC. Sustained Suppression of Hyperalgesia during Latent Sensitization by μ-, δ-, and κ-opioid receptors and α2A Adrenergic Receptors: Role of Constitutive Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2016 January 6;36(1):204-21. PubMed PMID: 26740662; PubMed Central PMCID: PMC4701961.

                  Birtolo C, Go VL, Ptasznik A, Eibl G, Pandol SJ. Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas. 2016 January;45(1):21-31. PubMed PMID: 26658038; PubMed Central PMCID: PMC4859755.

                  Camus M, Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi KA, Machicado GA, Dulai GS, Jensen ME, Gornbein JA. Comparison of Three Risk Scores to Predict Outcomes of Severe Lower Gastrointestinal Bleeding. Journal of clinical gastroenterology. 2016 January;50(1):52-8. PubMed PMID: 25599218; PubMed Central PMCID: PMC4504830.

                  Hoffman JM, Baritaki S, Ruiz JJ, Sideri A, Pothoulakis C. Corticotropin-Releasing Hormone Receptor 2 Signaling Promotes Mucosal Repair Responses after Colitis. The American journal of pathology. 2016 January;186(1):134-44. PubMed PMID: 26597886; PubMed Central PMCID: PMC4714033.

                  Hong JY, Naliboff B, Labus JS, Gupta A, Kilpatrick LA, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Mayer EA. Altered brain responses in subjects with irritable bowel syndrome during cued and uncued pain expectation. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 January;28(1):127-38. PubMed PMID: 26526698; PubMed Central PMCID: PMC4943658.

                  Jarcho JM, Feier NA, Labus JS, Naliboff B, Smith SR, Hong JY, Colloca L, Tillisch K, Mandelkern MA, Mayer EA, London ED. Placebo analgesia: Self-report measures and preliminary evidence of cortical dopamine release associated with placebo response. NeuroImage. Clinical. 2016;10:107-14. PubMed PMID: 26759785; PubMed Central PMCID: PMC4683423.

                  Jensen DM, Ohning GV, Kovacs TO, Ghassemi KA, Jutabha R, Dulai GS, Machicado GA. Doppler endoscopic probe as a guide to risk stratification and definitive hemostasis of peptic ulcer bleeding. Gastrointestinal endoscopy. 2016 January;83(1):129-36. PubMed PMID: 26318834; PubMed Central PMCID: PMC4691549.

                  Labus JS, Naliboff B, Kilpatrick L, Liu C, Ashe-McNalley C, dos Santos IR, Alaverdyan M, Woodworth D, Gupta A, Ellingson BM, Tillisch K, Mayer EA. Pain and Interoception Imaging Network (PAIN): A multimodal, multisite, brain-imaging repository for chronic somatic and visceral pain disorders. NeuroImage. 2016 January 1;124(Pt B):1232-7. PubMed PMID: 25902408; PubMed Central PMCID: PMC4627849.

                  Latorre R, Huynh J, Mazzoni M, Gupta A, Bonora E, Clavenzani P, Chang L, Mayer EA, De Giorgio R, Sternini C. Expression of the Bitter Taste Receptor, T2R38, in Enteroendocrine Cells of the Colonic Mucosa of Overweight/Obese vs. Lean Subjects. PloS one. 2016;11(2):e0147468. PubMed PMID: 26866366; PubMed Central PMCID: PMC4750998.

                  Moussaoui N, Larauche M, Biraud M, Molet J, Million M, Mayer E, Taché Y. Limited Nesting Stress Alters Maternal Behavior and In Vivo Intestinal Permeability in Male Wistar Pup Rats. PloS one. 2016;11(5):e0155037. PubMed PMID: 27149676; PubMed Central PMCID: PMC4858303.

                  Rouch JD, Scott A, Lei NY, Solorzano-Vargas RS, Wang J, Hanson EM, Kobayashi M, Lewis M, Stelzner MG, Dunn JC, Eckmann L, Martín MG. Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. PloS one. 2016;11(1):e0148216. PubMed PMID: 26820624; PubMed Central PMCID: PMC4731053.

                  Zhou G, Yu J, Wang A, Liu SH, Sinnett-Smith J, Wu J, Sanchez R, Nemunaitis J, Ricordi C, Rozengurt E, Brunicardi FC. Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma. Current molecular medicine. 2016;16(1):83-90. PubMed PMID: 26695692; PubMed Central PMCID: PMC4994969.

                  Vuong HE, Hardi CN, Barnes S, Brecha NC. Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 December 2;35(48):15955-70. PubMed PMID: 26631476; PubMed Central PMCID: PMC4666919.

                  Kilpatrick LA, Istrin JJ, Gupta A, Naliboff BD, Tillisch K, Labus JS, Mayer EA. Sex commonalities and differences in the relationship between resilient personality and the intrinsic connectivity of the salience and default mode networks. Biological psychology. 2015 December;112:107-15. PubMed PMID: 26440126; PubMed Central PMCID: PMC5012423.

                  Phan J, Benhammou JN, Pisegna JR. Gastric Hypersecretory States: Investigation and Management. Current treatment options in gastroenterology. 2015 December;13(4):386-97. PubMed PMID: 26342486; PubMed Central PMCID: PMC4633316.

                  Stark AP, Chang HH, Jung X, Moro A, Hertzer K, Xu M, Schmidt A, Hines OJ, Eibl G. E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice. Surgery. 2015 December;158(6):1564-72. PubMed PMID: 26297056; PubMed Central PMCID: PMC4637247.

                  Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of experimental medicine. 2015 November 16;212(12):2147-63. PubMed PMID: 26552708; PubMed Central PMCID: PMC4647265.

                  Chang HH, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G. Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1. American journal of physiology. Cell physiology. 2015 November 15;309(10):C639-49. PubMed PMID: 26310818; PubMed Central PMCID: PMC4652080.

                  Vu JP, Goyal D, Luong L, Oh S, Sandhu R, Norris J, Parsons W, Pisegna JR, Germano PM. PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin. American journal of physiology. Gastrointestinal and liver physiology. 2015 November 15;309(10):G816-25. PubMed PMID: 26336928; PubMed Central PMCID: PMC4652141.

                  Young SH, Rey O, Rozengurt E. Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: Impact of the highly conservative mutation Ser170Thr. Biochemical and biophysical research communications. 2015 November 6;467(1):1-6. PubMed PMID: 26431875; PubMed Central PMCID: PMC4613767.

                  Rodriguez JA, Huerta-Yepez S, Law IK, Baay-Guzman GJ, Tirado-Rodriguez B, Hoffman JM, Iliopoulos D, Hommes DW, Verspaget HW, Chang L, Pothoulakis C, Baritaki S. Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling. Cellular and molecular gastroenterology and hepatology. 2015 November 1;1(6):610-630. PubMed PMID: 26495412; PubMed Central PMCID: PMC4610032.

                  Vuong HE, Pérez de Sevilla Müller L, Hardi CN, McMahon DG, Brecha NC. Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines. Neuroscience. 2015 October 29;307:319-37. PubMed PMID: 26335381; PubMed Central PMCID: PMC4603663.

                  Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D. MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice. Gastroenterology. 2015 October;149(4):981-92.e11. PubMed PMID: 26055138; PubMed Central PMCID: PMC4584179.

                  Fang K, Sideri A, Law IK, Bakirtzi K, Polytarchou C, Iliopoulos D, Pothoulakis C. Identification of a novel substance P (SP)-neurokinin-1 receptor (NK-1R) microRNA-221-5p inflammatory network in human colonic epithelial cells. Cellular and molecular gastroenterology and hepatology. 2015 September 1;1(5):503-515. PubMed PMID: 26645045; PubMed Central PMCID: PMC4669978.

                  Hubbard CS, Hong J, Jiang Z, Ebrat B, Suyenobu B, Smith S, Heendeniya N, Naliboff BD, Tillisch K, Mayer EA, Labus JS. Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 September;27(9):1282-94. PubMed PMID: 26087779; PubMed Central PMCID: PMC4550526.

                  Cherukuri DP, Deignan JL, Das K, Grody WW, Herschman H. Instability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma. Molecular oncology. 2015 August;9(7):1252-8. PubMed PMID: 25817443; PubMed Central PMCID: PMC4523444.

                  Irimia A, Labus JS, Torgerson CM, Van Horn JD, Mayer EA. Altered viscerotopic cortical innervation in patients with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 August;27(8):1075-81. PubMed PMID: 25952540; PubMed Central PMCID: PMC4520752.

                  Kaunitz JD. The Discovery of PCR: ProCuRement of Divine Power. Digestive diseases and sciences. 2015 August;60(8):2230-1. PubMed PMID: 26077976; PubMed Central PMCID: PMC4501591.

                  Kobayashi M, Lei NY, Wang Q, Wu BM, Dunn JC. Orthogonally oriented scaffolds with aligned fibers for engineering intestinal smooth muscle. Biomaterials. 2015 August;61:75-84. PubMed PMID: 26001072; PubMed Central PMCID: PMC4464968.

                  Labus JS, Van Horn JD, Gupta A, Alaverdyan M, Torgerson C, Ashe-McNalley C, Irimia A, Hong JY, Naliboff B, Tillisch K, Mayer EA. Multivariate morphological brain signatures predict patients with chronic abdominal pain from healthy control subjects. Pain. 2015 August;156(8):1545-54. PubMed PMID: 25906347; PubMed Central PMCID: PMC4504800.

                  O'Mahony F, Wroblewski K, O'Byrne SM, Jiang H, Clerkin K, Benhammou J, Blaner WS, Beaven SW. Liver X receptors balance lipid stores in hepatic stellate cells through Rab18, a retinoid responsive lipid droplet protein. Hepatology (Baltimore, Md.). 2015 August;62(2):615-26. PubMed PMID: 25482505; PubMed Central PMCID: PMC4458237.

                  Tuominen I, Beaven SW. Intestinal farnesoid X receptor puts a fresh coat of wax on fatty liver. Hepatology (Baltimore, Md.). 2015 August;62(2):646-8. PubMed PMID: 25998695; PubMed Central PMCID: PMC4523235.

                  Law IK, Bakirtzi K, Polytarchou C, Oikonomopoulos A, Hommes D, Iliopoulos D, Pothoulakis C. Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis. Gut. 2015 July;64(7):1095-104. PubMed PMID: 25112884; PubMed Central PMCID: PMC4422787.

                  Lugea A, Waldron RT, Pandol SJ. Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2015 July;15(4 Suppl):S1-5. PubMed PMID: 25736240; PubMed Central PMCID: PMC4515411.

                  Stengel A, Karasawa H, Taché Y. The role of brain somatostatin receptor 2 in the regulation of feeding and drinking behavior. Hormones and behavior. 2015 July;73:15-22. PubMed PMID: 26026616; PubMed Central PMCID: PMC4546908.

                  Sanmiguel C, Gupta A, Mayer EA. Gut Microbiome and Obesity: A Plausible Explanation for Obesity. Current obesity reports. 2015 June;4(2):250-61. PubMed PMID: 26029487; PubMed Central PMCID: PMC4443745.

                  Vu JP, Larauche M, Flores M, Luong L, Norris J, Oh S, Liang LJ, Waschek J, Pisegna JR, Germano PM. Regulation of Appetite, Body Composition, and Metabolic Hormones by Vasoactive Intestinal Polypeptide (VIP). Journal of molecular neuroscience : MN. 2015 June;56(2):377-87. PubMed PMID: 25904310; PubMed Central PMCID: PMC4458420.

                  Gupta A, Rapkin AJ, Gill Z, Kilpatrick L, Fling C, Stains J, Masghati S, Tillisch K, Mayer EA, Labus JS. Disease-related differences in resting-state networks: a comparison between localized provoked vulvodynia, irritable bowel syndrome, and healthy control subjects. Pain. 2015 May;156(5):809-19. PubMed PMID: 25735001; PubMed Central PMCID: PMC4402252.

                  Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D. A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. Inflammatory bowel diseases. 2015 May;21(5):996-1005. PubMed PMID: 25738378; PubMed Central PMCID: PMC4402238.

                  Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JC, Martin MG, Lagasse E, Zhang L, Yu J. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Scientific reports. 2015 April 10;5:8566. PubMed PMID: 25858503; PubMed Central PMCID: PMC4392360.

                  Wu JX, Liu SH, Nemunaitis JJ, Brunicardi FC. Liposomal insulin promoter-thymidine kinase gene therapy followed by ganciclovir effectively ablates human pancreatic cancer in mice. Cancer letters. 2015 April 10;359(2):206-10. PubMed PMID: 25596375; PubMed Central PMCID: PMC4336837.

                  Akiba Y, Kaunitz JD, Million M. Peripheral corticotropin-releasing factor receptor type 2 activation increases colonic blood flow through nitric oxide pathway in rats. Digestive diseases and sciences. 2015 April;60(4):858-67. PubMed PMID: 25701320; PubMed Central PMCID: PMC4501405.

                  Anselmi L, Huynh J, Duraffourd C, Jaramillo I, Vegezzi G, Saccani F, Boschetti E, Brecha NC, De Giorgio R, Sternini C. Activation of μ opioid receptors modulates inflammation in acute experimental colitis. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 April;27(4):509-23. PubMed PMID: 25690069; PubMed Central PMCID: PMC4405133.

                  Liu Z, Sun F, Braun J, McGovern DP, Piantadosi S. Multilevel regularized regression for simultaneous taxa selection and network construction with metagenomic count data. Bioinformatics (Oxford, England). 2015 April 1;31(7):1067-74. PubMed PMID: 25416747; PubMed Central PMCID: PMC4382903.

                  Marvizon JC, Walwyn W, Minasyan A, Chen W, Taylor BK. Latent sensitization: a model for stress-sensitive chronic pain. Current protocols in neuroscience. 2015 April 1;71:9.50.1-14. PubMed PMID: 25829356; PubMed Central PMCID: PMC4532319.

                  Mayer EA, Gupta A, Kilpatrick LA, Hong JY. Imaging brain mechanisms in chronic visceral pain. Pain. 2015 April;156 Suppl 1:S50-63. PubMed PMID: 25789437; PubMed Central PMCID: PMC4428597.

                  Sideri A, Stavrakis D, Bowe C, Shih DQ, Fleshner P, Arsenescu V, Arsenescu R, Turner JR, Pothoulakis C, Karagiannides I. Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1. American journal of physiology. Gastrointestinal and liver physiology. 2015 April 1;308(7):G591-604. PubMed PMID: 25591865; PubMed Central PMCID: PMC4385897.

                  Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2. Molecular cancer therapeutics. 2015 April;14(4):1014-23. PubMed PMID: 25673820; PubMed Central PMCID: PMC4394038.

                  Tarling EJ, Ahn H, de Aguiar Vallim TQ. The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2. Arteriosclerosis, thrombosis, and vascular biology. 2015 April;35(4):787-95. PubMed PMID: 25593129; PubMed Central PMCID: PMC4376635.

                  Gukovsky I, Gukovskaya AS. Impaired autophagy triggers chronic pancreatitis: lessons from pancreas-specific atg5 knockout mice. Gastroenterology. 2015 March;148(3):501-5. PubMed PMID: 25613315; PubMed Central PMCID: PMC4443443.

                  Liu Y, Ji H, Zhang Y, Shen X, Gao F, He X, Li GA, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury. Journal of hepatology. 2015 March;62(3):563-72. PubMed PMID: 25450716; PubMed Central PMCID: PMC4336640.

                  Sakanaka T, Inoue T, Yorifuji N, Iguchi M, Fujiwara K, Narabayashi K, Kakimoto K, Nouda S, Okada T, Kuramoto T, Ishida K, Abe Y, Takeuchi T, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. The effects of a TGR5 agonist and a dipeptidyl peptidase IV inhibitor on dextran sulfate sodium-induced colitis in mice. Journal of gastroenterology and hepatology. 2015 March;30 Suppl 1:60-5. PubMed PMID: 25827806; PubMed Central PMCID: PMC4874188.

                  Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. The Journal of biological chemistry. 2015 February 27;290(9):5566-81. PubMed PMID: 25468909; PubMed Central PMCID: PMC4342471.

                  Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. Septin dynamics are essential for exocytosis. The Journal of biological chemistry. 2015 February 27;290(9):5280-97. PubMed PMID: 25575596; PubMed Central PMCID: PMC4342448.

                  Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell metabolism. 2015 February 3;21(2):334-46. PubMed PMID: 25651185; PubMed Central PMCID: PMC4349439.

                  de Aguiar Vallim TQ, Tarling EJ, Ahn H, Hagey LR, Romanoski CE, Lee RG, Graham MJ, Motohashi H, Yamamoto M, Edwards PA. MAFG is a transcriptional repressor of bile acid synthesis and metabolism. Cell metabolism. 2015 February 3;21(2):298-310. PubMed PMID: 25651182; PubMed Central PMCID: PMC4317590.

                  Bromley EG, May FP, Federer L, Spiegel BM, van Oijen MG. Explaining persistent under-use of colonoscopic cancer screening in African Americans: a systematic review. Preventive medicine. 2015 February;71:40-8. PubMed PMID: 25481094; PubMed Central PMCID: PMC4329030.

                  Kaji I, Iwanaga T, Watanabe M, Guth PH, Engel E, Kaunitz JD, Akiba Y. SCFA transport in rat duodenum. American journal of physiology. Gastrointestinal and liver physiology. 2015 February 1;308(3):G188-97. PubMed PMID: 25394661; PubMed Central PMCID: PMC4312951.

                  Nguyen AH, Toste PA, Farrell JJ, Clerkin BM, Williams J, Muthusamy VR, Watson RR, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Current recommendations for surveillance and surgery of intraductal papillary mucinous neoplasms may overlook some patients with cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2015 February;19(2):258-65. PubMed PMID: 25373706; PubMed Central PMCID: PMC4305480.

                  Tan YV, Abad C, Wang Y, Lopez R, Waschek J. VPAC2 (vasoactive intestinal peptide receptor type 2) receptor deficient mice develop exacerbated experimental autoimmune encephalomyelitis with increased Th1/Th17 and reduced Th2/Treg responses. Brain, behavior, and immunity. 2015 February;44:167-175. PubMed PMID: 25305591; PubMed Central PMCID: PMC4275378.

                  Taché Y, Million M. Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia. Journal of neurogastroenterology and motility. 2015 January 31;21(1):8-24. PubMed PMID: 25611064; PubMed Central PMCID: PMC4288101.

                  Coveleskie K, Gupta A, Kilpatrick LA, Mayer ED, Ashe-McNalley C, Stains J, Labus JS, Mayer EA. Altered functional connectivity within the central reward network in overweight and obese women. Nutrition & diabetes. 2015 January 19;5:e148. PubMed PMID: 25599560; PubMed Central PMCID: PMC4314578.

                  Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology. 2015 January 15;475:46-55. PubMed PMID: 25462345; PubMed Central PMCID: PMC4284078.

                  Abad C, Cheung-Lau G, Coûté-Monvoisin AC, Waschek JA. Vasoactive intestinal peptide-deficient mice exhibit reduced pathology in trinitrobenzene sulfonic acid-induced colitis. Neuroimmunomodulation. 2015;22(3):203-12. PubMed PMID: 25301381; PubMed Central PMCID: PMC4297532.

                  Bradesi S, Karagiannides I, Bakirtzi K, Joshi SM, Koukos G, Iliopoulos D, Pothoulakis C, Mayer EA. Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat. PloS one. 2015;10(7):e0130938. PubMed PMID: 26222740; PubMed Central PMCID: PMC4519289.

                  Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. Journal of Alzheimer's disease : JAD. 2015;43(3):967-76. PubMed PMID: 25125464; PubMed Central PMCID: PMC4258165.

                  Chen R, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM, Maitra A, Brentnall TA. Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. Laboratory investigation; a journal of technical methods and pathology. 2015 January;95(1):43-55. PubMed PMID: 25347153; PubMed Central PMCID: PMC4281293.

                  Cheng M, Ho S, Yoo JH, Tran DH, Bakirtzi K, Su B, Tran DH, Kubota Y, Ichikawa R, Koon HW. Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts. Clinical and experimental gastroenterology. 2015;8:13-29. PubMed PMID: 25565877; PubMed Central PMCID: PMC4274046.

                  Gupta A, Mayer EA, Sanmiguel CP, Van Horn JD, Woodworth D, Ellingson BM, Fling C, Love A, Tillisch K, Labus JS. Patterns of brain structural connectivity differentiate normal weight from overweight subjects. NeuroImage. Clinical. 2015;7:506-17. PubMed PMID: 25737959; PubMed Central PMCID: PMC4338207.

                  Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 January 1;21(1):157-65. PubMed PMID: 25348515; PubMed Central PMCID: PMC4286535.

                  Khalil HA, Lei NY, Nie W, Lewis MS, Stelzner MG, Martín MG, Dunn JC, Yoo J. Primary Myofibroblasts Maintain Short-Term Viability following Submucosal Injection in Syngeneic, Immune-Competent Mice Utilizing Murine Colonoscopy. PloS one. 2015;10(5):e0127258. PubMed PMID: 26016485; PubMed Central PMCID: PMC4445916.

                  Kutch JJ, Yani MS, Asavasopon S, Kirages DJ, Rana M, Cosand L, Labus JS, Kilpatrick LA, Ashe-McNalley C, Farmer MA, Johnson KA, Ness TJ, Deutsch G, Harris RE, Apkarian AV, Clauw DJ, Mackey SC, Mullins C, Mayer EA. Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study. NeuroImage. Clinical. 2015;8:493-502. PubMed PMID: 26106574; PubMed Central PMCID: PMC4474411.

                  Law IK, Pothoulakis C. MicroRNA-133α regulates neurotensin-associated colonic inflammation in colonic epithelial cells and experimental colitis. RNA & disease (Houston, Tex.). 2015;2(1). PubMed PMID: 26005712; PubMed Central PMCID: PMC4441413.

                  Li Y, Go VL, Sarkar FH. The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome. Pancreas. 2015 January;44(1):1-10. PubMed PMID: 25493373; PubMed Central PMCID: PMC4264839.

                  Martinez L, Ermolova NV, Ishikawa TO, Stout DB, Herschman HR, Spencer MJ. A reporter mouse for optical imaging of inflammation in mdx muscles. Skeletal muscle. 2015;5:15. PubMed PMID: 25949789; PubMed Central PMCID: PMC4422315.

                  Marzagalli R, Scuderi S, Drago F, Waschek JA, Castorina A. Emerging Role of PACAP as a New Potential Therapeutic Target in Major Diabetes Complications. International journal of endocrinology. 2015;2015:160928. PubMed PMID: 26074958; PubMed Central PMCID: PMC4446501.

                  McGowan I, Anton PA, Elliott J, Cranston RD, Duffill K, Althouse AD, Hawkins KL, De Rosa SC. Exploring the feasibility of multi-site flow cytometric processing of gut associated lymphoid tissue with centralized data analysis for multi-site clinical trials. PloS one. 2015;10(5):e0126454. PubMed PMID: 26010577; PubMed Central PMCID: PMC4444258.

                  Mulak A, Larauche M, Biraud M, Million M, Rivier J, Taché Y. Selective agonists of somatostatin receptor subtype 1 or 2 injected peripherally induce antihyperalgesic effect in two models of visceral hypersensitivity in mice. Peptides. 2015 January;63:71-80. PubMed PMID: 25451334; PubMed Central PMCID: PMC4385413.

                  Orand A, Gupta A, Shih W, Presson AP, Hammer C, Niesler B, Heendeniya N, Mayer EA, Chang L. Catecholaminergic Gene Polymorphisms Are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome. PloS one. 2015;10(8):e0135910. PubMed PMID: 26288143; PubMed Central PMCID: PMC4546052.

                  Taché Y. Corticotrophin-releasing factor 1 activation in the central amygdale and visceral hyperalgesia. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 January;27(1):1-6. PubMed PMID: 25557223; PubMed Central PMCID: PMC4389773.

                  Wang L, Mogami S, Yakabi S, Karasawa H, Yamada C, Yakabi K, Hattori T, Taché Y. Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito. PloS one. 2015;10(9):e0139325. PubMed PMID: 26421719; PubMed Central PMCID: PMC4589401.

                  Wang Y, Yan C, Liu L, Wang W, Du H, Fan W, Lutfy K, Jiang M, Friedman TC, Liu Y. 11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue. American journal of physiology. Endocrinology and metabolism. 2015 January 1;308(1):E84-95. PubMed PMID: 25389364; PubMed Central PMCID: PMC4281684.

                  Yoo JH, Ho S, Tran DH, Cheng M, Bakirtzi K, Kukota Y, Ichikawa R, Su B, Tran DH, Hing TC, Chang I, Shih DQ, Issacson RE, Gallo RL, Fiocchi C, Pothoulakis C, Koon HW. Anti-fibrogenic effects of the anti-microbial peptide cathelicidin in murine colitis-associated fibrosis. Cellular and molecular gastroenterology and hepatology. 2015 January;1(1):55-74.e1. PubMed PMID: 25729764; PubMed Central PMCID: PMC4338438.

                  Zhu J, Lu T, Yue S, Shen X, Gao F, Busuttil RW, Kupiec-Weglinski JW, Xia Q, Zhai Y. Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation. Transplantation. 2015 January;99(1):48-55. PubMed PMID: 25340604; PubMed Central PMCID: PMC4272660.

                  Akiba Y, Kaunitz JD. Prostaglandin pathways in duodenal chemosensing. Journal of gastroenterology and hepatology. 2014 December;29 Suppl 4:93-8. PubMed PMID: 25521740; PubMed Central PMCID: PMC4451058.

                  Bagarinao E, Johnson KA, Martucci KT, Ichesco E, Farmer MA, Labus J, Ness TJ, Harris R, Deutsch G, Apkarian AV, Mayer EA, Clauw DJ, Mackey S. Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network study. Pain. 2014 December;155(12):2502-9. PubMed PMID: 25242566; PubMed Central PMCID: PMC4504202.

                  Buzzanco A, Gomez A, Rodriguez E, French BA, Tillman BA, Chang S, Ganapathy E, Junrungsee S, Zarrinpar A, Agopian VG, Naini BV, French SW Jr, French SW Sr. Digital quantitation of HCC-associated stem cell markers and protein quality control factors using tissue arrays of human liver sections. Experimental and molecular pathology. 2014 December;97(3):399-410. PubMed PMID: 25218810; PubMed Central PMCID: PMC4262606.

                  Donahue TR, Nguyen AH, Moughan J, Li L, Tatishchev S, Toste P, Farrell JJ. Stromal microRNA-21 levels predict response to 5-fluorouracil in patients with pancreatic cancer. Journal of surgical oncology. 2014 December;110(8):952-9. PubMed PMID: 25132574; PubMed Central PMCID: PMC4232442.

                  Ji H, Liu Y, Zhang Y, Shen XD, Gao F, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. T-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury. Hepatology (Baltimore, Md.). 2014 December;60(6):2052-2064. PubMed PMID: 25066922; PubMed Central PMCID: PMC4396987.

                  Karasawa H, Pietra C, Giuliano C, Garcia-Rubio S, Xu X, Yakabi S, Taché Y, Wang L. New ghrelin agonist, HM01 alleviates constipation and L-dopa-delayed gastric emptying in 6-hydroxydopamine rat model of Parkinson's disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 December;26(12):1771-82. PubMed PMID: 25327342; PubMed Central PMCID: PMC4457321.

                  Stengel A, Taché Y. Brain peptides and the modulation of postoperative gastric ileus. Current opinion in pharmacology. 2014 December;19:31-7. PubMed PMID: 24999843; PubMed Central PMCID: PMC4254047.

                  Wagner JP, Sullins VF, Dunn JC. Skin-derived precursors generate enteric-type neurons in aganglionic jejunum. Journal of pediatric surgery. 2014 December;49(12):1809-14. PubMed PMID: 25487489; PubMed Central PMCID: PMC4261145.

                  Wagner JP, Sullins VF, Khalil HA, Dunn JC. A durable model of Hirschsprung's colon. Journal of pediatric surgery. 2014 December;49(12):1804-8. PubMed PMID: 25487488; PubMed Central PMCID: PMC4261142.

                  Hong C, Marshall SM, McDaniel AL, Graham M, Layne JD, Cai L, Scotti E, Boyadjian R, Kim J, Chamberlain BT, Tangirala RK, Jung ME, Fong L, Lee R, Young SG, Temel RE, Tontonoz P. The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice. Cell metabolism. 2014 November 4;20(5):910-8. PubMed PMID: 25440061; PubMed Central PMCID: PMC4261644.

                  Tong M, Jacobs JP, McHardy IH, Braun J. Sampling of intestinal microbiota and targeted amplification of bacterial 16S rRNA genes for microbial ecologic analysis. Current protocols in immunology. 2014 November 3;107:7.41.1-11. PubMed PMID: 25367129; PubMed Central PMCID: PMC4457454.

                  Balaji K, French CT, Miller JF, Colicelli J. The RAB5-GEF function of RIN1 regulates multiple steps during Listeria monocytogenes infection. Traffic (Copenhagen, Denmark). 2014 November;15(11):1206-18. PubMed PMID: 25082076; PubMed Central PMCID: PMC4282165.

                  Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR. Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. Molecular cancer research : MCR. 2014 November;12(11):1677-88. PubMed PMID: 25063587; PubMed Central PMCID: PMC4233191.

                  Rozengurt E, Soares HP, Sinnet-Smith J. Suppression of feedback loops mediated by PI3K/mTOR induces multiple overactivation of compensatory pathways: an unintended consequence leading to drug resistance. Molecular cancer therapeutics. 2014 November;13(11):2477-88. PubMed PMID: 25323681; PubMed Central PMCID: PMC4222988.

                  Shih DQ, Zheng L, Zhang X, Zhang H, Kanazawa Y, Ichikawa R, Wallace KL, Chen J, Pothoulakis C, Koon HW, Targan SR. Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis. Mucosal immunology. 2014 November;7(6):1492-503. PubMed PMID: 24850426; PubMed Central PMCID: PMC4205266.

                  Spiegel BM, Hays RD, Bolus R, Melmed GY, Chang L, Whitman C, Khanna PP, Paz SH, Hays T, Reise S, Khanna D. Development of the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) gastrointestinal symptom scales. The American journal of gastroenterology. 2014 November;109(11):1804-14. PubMed PMID: 25199473; PubMed Central PMCID: PMC4285435.

                  Hong JY, Kilpatrick LA, Labus JS, Gupta A, Katibian D, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Naliboff B, Mayer EA. Sex and disease-related alterations of anterior insula functional connectivity in chronic abdominal pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 October 22;34(43):14252-9. PubMed PMID: 25339739; PubMed Central PMCID: PMC4205551.

                  Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Molecular cancer therapeutics. 2014 October;13(10):2303-14. PubMed PMID: 25082960; PubMed Central PMCID: PMC4188417.

                  Itoh Y, Arnold AP. X chromosome regulation of autosomal gene expression in bovine blastocysts. Chromosoma. 2014 October;123(5):481-9. PubMed PMID: 24817096; PubMed Central PMCID: PMC4170013.

                  Ruegger PM, Clark RT, Weger JR, Braun J, Borneman J. Improved resolution of bacteria by high throughput sequence analysis of the rRNA internal transcribed spacer. Journal of microbiological methods. 2014 October;105:82-7. PubMed PMID: 25034229; PubMed Central PMCID: PMC4160368.

                  Arnold AP. Conceptual frameworks and mouse models for studying sex differences in physiology and disease: why compensation changes the game. Experimental neurology. 2014 September;259:2-9. PubMed PMID: 24509348; PubMed Central PMCID: PMC4125548.

                  Im E, Jung J, Pothoulakis C, Rhee SH. Disruption of Pten speeds onset and increases severity of spontaneous colitis in Il10(-/-) mice. Gastroenterology. 2014 September;147(3):667-679.e10. PubMed PMID: 24882466; PubMed Central PMCID: PMC4143453.

                  Liu Y, Yuan J, Tan T, Jia W, Lugea A, Mareninova O, Waldron RT, Pandol SJ. Genetic inhibition of protein kinase Cε attenuates necrosis in experimental pancreatitis. American journal of physiology. Gastrointestinal and liver physiology. 2014 September 1;307(5):G550-63. PubMed PMID: 25035113; PubMed Central PMCID: PMC4154116.

                  Costes S, Butler PC. Insulin-degrading enzyme inhibition, a novel therapy for type 2 diabetes?. Cell metabolism. 2014 August 5;20(2):201-3. PubMed PMID: 25100059; PubMed Central PMCID: PMC4144405.

                  Calkin AC, Lee SD, Kim J, Van Stijn CM, Wu XH, Lusis AJ, Hong C, Tangirala RI, Tontonoz P. Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in mice. Circulation research. 2014 August 1;115(4):442-9. PubMed PMID: 24935961; PubMed Central PMCID: PMC4119488.

                  Koon HW, Ho S, Hing TC, Cheng M, Chen X, Ichikawa Y, Kelly CP, Pothoulakis C. Fidaxomicin inhibits Clostridium difficile toxin A-mediated enteritis in the mouse ileum. Antimicrobial agents and chemotherapy. 2014 August;58(8):4642-50. PubMed PMID: 24890583; PubMed Central PMCID: PMC4135997.

                  Ngun TC, Ghahramani NM, Creek MM, Williams-Burris SM, Barseghyan H, Itoh Y, Sánchez FJ, McClusky R, Sinsheimer JS, Arnold AP, Vilain E. Feminized behavior and brain gene expression in a novel mouse model of Klinefelter Syndrome. Archives of sexual behavior. 2014 August;43(6):1043-57. PubMed PMID: 24923877; PubMed Central PMCID: PMC4371776.

                  Viitasalo L, Niemi L, Ashorn M, Ashorn S, Braun J, Huhtala H, Collin P, Mäki M, Kaukinen K, Kurppa K, Iltanen S. Early microbial markers of celiac disease. Journal of clinical gastroenterology. 2014 August;48(7):620-4. PubMed PMID: 24518796; PubMed Central PMCID: PMC4082475.

                  Karasawa H, Yakabi S, Wang L, Taché Y. Orexin-1 receptor mediates the increased food and water intake induced by intracerebroventricular injection of the stable somatostatin pan-agonist, ODT8-SST in rats. Neuroscience letters. 2014 July 25;576:88-92. PubMed PMID: 24915296; PubMed Central PMCID: PMC4096604.

                  Lin L, Ma C, Wei B, Aziz N, Rajalingam R, Yusung S, Erlich HA, Trachtenberg EA, Targan SR, McGovern DP, Heath JR, Braun J. Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function. Journal of immunology (Baltimore, Md. : 1950). 2014 July 15;193(2):940-9. PubMed PMID: 24935928; PubMed Central PMCID: PMC4096688.

                  Gupta A, Kilpatrick L, Labus J, Tillisch K, Braun A, Hong JY, Ashe-McNalley C, Naliboff B, Mayer EA. Early adverse life events and resting state neural networks in patients with chronic abdominal pain: evidence for sex differences. Psychosomatic medicine. 2014 July;76(6):404-12. PubMed PMID: 25003944; PubMed Central PMCID: PMC4113723.

                  Inoue T, Higashiyama M, Kaji I, Rudenkyy S, Higuchi K, Guth PH, Engel E, Kaunitz JD, Akiba Y. Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats. Digestive diseases and sciences. 2014 June;59(6):1286-95. PubMed PMID: 24379150; PubMed Central PMCID: PMC4196264.

                  Sallam T, Ito A, Rong X, Kim J, van Stijn C, Chamberlain BT, Jung ME, Chao LC, Jones M, Gilliland T, Wu X, Su GL, Tangirala RK, Tontonoz P, Hong C. The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis. Journal of lipid research. 2014 June;55(6):1120-30. PubMed PMID: 24671012; PubMed Central PMCID: PMC4031943.

                  Chen W, McRoberts JA, Marvizón JC. μ-Opioid receptor inhibition of substance P release from primary afferents disappears in neuropathic pain but not inflammatory pain. Neuroscience. 2014 May 16;267:67-82. PubMed PMID: 24583035; PubMed Central PMCID: PMC3998911.

                  Sinnett-Smith J, Ni Y, Wang J, Ming M, Young SH, Rozengurt E. Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling. American journal of physiology. Cell physiology. 2014 May 15;306(10):C961-71. PubMed PMID: 24647541; PubMed Central PMCID: PMC4024715.

                  Chen W, Walwyn W, Ennes HS, Kim H, McRoberts JA, Marvizón JC. BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals. The European journal of neuroscience. 2014 May;39(9):1439-54. PubMed PMID: 24611998; PubMed Central PMCID: PMC4122572.

                  Kilpatrick LA, Coveleskie K, Connolly L, Labus JS, Ebrat B, Stains J, Jiang Z, Suyenobu BY, Raybould HE, Tillisch K, Mayer EA. Influence of sucrose ingestion on brainstem and hypothalamic intrinsic oscillations in lean and obese women. Gastroenterology. 2014 May;146(5):1212-21. PubMed PMID: 24480616; PubMed Central PMCID: PMC4113508.

                  Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle. Virology. 2014 April;454-455:118-27. PubMed PMID: 24725938; PubMed Central PMCID: PMC4011396.

                  Mulak A, Taché Y, Larauche M. Sex hormones in the modulation of irritable bowel syndrome. World journal of gastroenterology. 2014 March 14;20(10):2433-48. PubMed PMID: 24627581; PubMed Central PMCID: PMC3949254.

                  Du S, Itoh N, Askarinam S, Hill H, Arnold AP, Voskuhl RR. XY sex chromosome complement, compared with XX, in the CNS confers greater neurodegeneration during experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 2014 February 18;111(7):2806-11. PubMed PMID: 24550311; PubMed Central PMCID: PMC3932937.

                  Abad C, Nobuta H, Li J, Kasai A, Yong WH, Waschek JA. Targeted STAT3 disruption in myeloid cells alters immunosuppressor cell abundance in a murine model of spontaneous medulloblastoma. Journal of leukocyte biology. 2014 February;95(2):357-67. PubMed PMID: 24068730; PubMed Central PMCID: PMC3896661.

                  Goebel-Stengel M, Stengel A, Wang L, Taché Y. Orexigenic response to tail pinch: role of brain NPY(1) and corticotropin releasing factor receptors. American journal of physiology. Regulatory, integrative and comparative physiology. 2014 February 1;306(3):R164-74. PubMed PMID: 24338440; PubMed Central PMCID: PMC3921301.

                  Young SH, Rey O, Sinnett-Smith J, Rozengurt E. Intracellular Ca2+ oscillations generated via the Ca2+-sensing receptor are mediated by negative feedback by PKCα at Thr888. American journal of physiology. Cell physiology. 2014 February 1;306(3):C298-306. PubMed PMID: 24336654; PubMed Central PMCID: PMC3919994.

                  Taylor BK, Fu W, Kuphal KE, Stiller CO, Winter MK, Chen W, Corder GF, Urban JH, McCarson KE, Marvizon JC. Inflammation enhances Y1 receptor signaling, neuropeptide Y-mediated inhibition of hyperalgesia, and substance P release from primary afferent neurons. Neuroscience. 2014 January 3;256:178-94. PubMed PMID: 24184981; PubMed Central PMCID: PMC4363128.

                  Duraffourd C, Kumala E, Anselmi L, Brecha NC, Sternini C. Opioid-induced mitogen-activated protein kinase signaling in rat enteric neurons following chronic morphine treatment. PloS one. 2014;9(10):e110230. PubMed PMID: 25302800; PubMed Central PMCID: PMC4193881.

                  Edderkaoui M, Eibl G. Risk factors for pancreatic cancer: underlying mechanisms and potential targets. Frontiers in physiology. 2014;5:490. PubMed PMID: 25540626; PubMed Central PMCID: PMC4261721.

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                  Gong J, Robbins LA, Lugea A, Waldron RT, Jeon CY, Pandol SJ. Diabetes, pancreatic cancer, and metformin therapy. Frontiers in physiology. 2014;5:426. PubMed PMID: 25426078; PubMed Central PMCID: PMC4224068.

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                  Ming M, Sinnett-Smith J, Wang J, Soares HP, Young SH, Eibl G, Rozengurt E. Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. PloS one. 2014;9(12):e114573. PubMed PMID: 25493642; PubMed Central PMCID: PMC4262417.

                  Richardson-Harman N, Hendrix CW, Bumpus NN, Mauck C, Cranston RD, Yang K, Elliott J, Tanner K, McGowan I, Kashuba A, Anton PA. Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study. PloS one. 2014;9(10):e111507. PubMed PMID: 25350130; PubMed Central PMCID: PMC4211741.

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                  Vu JP, Million M, Larauche M, Luong L, Norris J, Waschek JA, Pothoulakis C, Pisegna JR, Germano PM. Inhibition of vasoactive intestinal polypeptide (VIP) induces resistance to dextran sodium sulfate (DSS)-induced colitis in mice. Journal of molecular neuroscience : MN. 2014 January;52(1):37-47. PubMed PMID: 24395090; PubMed Central PMCID: PMC4114158.

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                  Ke B, Shen XD, Zhang Y, Ji H, Gao F, Yue S, Kamo N, Zhai Y, Yamamoto M, Busuttil RW, Kupiec-Weglinski JW. KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants. Journal of hepatology. 2013 December;59(6):1200-7. PubMed PMID: 23867319; PubMed Central PMCID: PMC4524560.

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                  Kisfalvi K, Moro A, Sinnett-Smith J, Eibl G, Rozengurt E. Metformin inhibits the growth of human pancreatic cancer xenografts. Pancreas. 2013 July;42(5):781-5. PubMed PMID: 23462329; PubMed Central PMCID: PMC3681894.

                  Sinnett-Smith J, Kisfalvi K, Kui R, Rozengurt E. Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK. Biochemical and biophysical research communications. 2013 January 4;430(1):352-7. PubMed PMID: 23159620; PubMed Central PMCID: PMC3545113.

                  Waldron RT, Innamorati G, Torres-Marquez ME, Sinnett-Smith J, Rozengurt E. Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq. Cellular signalling. 2012 April;24(4):914-21. PubMed PMID: 22227248; PubMed Central PMCID: PMC3286641.

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                  Rozengurt E, Sinnett-Smith J, Kisfalvi K. Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2010 May 1;16(9):2505-11. PubMed PMID: 20388847; PubMed Central PMCID: PMC2862089.

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                  Jiang X, Sinnett-Smith J, Rozengurt E. Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. Biochemical and biophysical research communications. 2009 September 25;387(3):521-4. PubMed PMID: 19615971; PubMed Central PMCID: PMC2754135.

                  Kisfalvi K, Eibl G, Sinnett-Smith J, Rozengurt E. Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer research. 2009 August 15;69(16):6539-45. PubMed PMID: 19679549; PubMed Central PMCID: PMC2753241.

                  Spiegel BM, Farid M, van Oijen MG, Laine L, Howden CW, Esrailian E. Adherence to best practice guidelines in dyspepsia: a survey comparing dyspepsia experts, community gastroenterologists and primary-care providers. Alimentary pharmacology & therapeutics. 2009 April 15;29(8):871-81. PubMed PMID: 19183152; PubMed Central PMCID: PMC2953468.

                  Desai AA, Bolus R, Nissenson A, Chertow GM, Bolus S, Solomon MD, Khawar OS, Talley J, Spiegel BM. Is there "cherry picking" in the ESRD Program? Perceptions from a Dialysis Provider Survey. Clinical journal of the American Society of Nephrology : CJASN. 2009 April;4(4):772-7. PubMed PMID: 19339407; PubMed Central PMCID: PMC2666440.

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                  McConalogue K, Grady EF, Minnis J, Balestra B, Tonini M, Brecha NC, Bunnett NW, Sternini C. Activation and internalization of the mu-opioid receptor by the newly discovered endogenous agonists, endomorphin-1 and endomorphin-2. Neuroscience. 1999 March;90(3):1051-9. PubMed PMID: 10218804; PubMed Central PMCID: PMC4472477

  Condro MC, Matynia A, Foster NN, Ago Y, Rajbhandari AK, Van C, Jayaram B, Parikh S, Diep AL, Nguyen E, May V, Dong HW, Waschek JA. High-resolution characterization of a PACAP-EGFP transgenic mouse model for mapping PACAP-expressing neurons. The Journal of comparative neurology. 2016 December 15;524(18):3827-3848. PubMed PMID: 27197019; PubMed Central PMCID: PMC5063673.

                  Duboc H, Tolstanova G, Yuan PQ, Wu V, Kaji I, Biraud M, Akiba Y, Kaunitz J, Million M, Tache Y, Larauche M. Reduction of epithelial secretion in male rat distal colonic mucosa by bile acid receptor TGR5 agonist, INT-777: role of submucosal neurons. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 November;28(11):1663-1676. PubMed PMID: 27259385; PubMed Central PMCID: PMC5083223.

                  Orand A, Naliboff B, Gadd M, Shih W, Ju T, Presson AP, Mayer EA, Chang L. Corticotropin-releasing hormone receptor 1 (CRH-R1) polymorphisms are associated with irritable bowel syndrome and acoustic startle response. Psychoneuroendocrinology. 2016 November;73:133-141. PubMed PMID: 27497153; PubMed Central PMCID: PMC5048544.

                  Koon HW, Su B, Xu C, Mussatto CC, Tran DH, Lee EC, Ortiz C, Wang J, Lee JE, Ho S, Chen X, Kelly CP, Pothoulakis C. Probiotic Saccharomyces boulardii CNCM I-745 prevents outbreak-associated Clostridium difficile-associated cecal inflammation in hamsters. American journal of physiology. Gastrointestinal and liver physiology. 2016 October 1;311(4):G610-G623. PubMed PMID: 27514478; PubMed Central PMCID: PMC5142203.

                  Hoang-Yen Tran D, Hoang-Ngoc Tran D, Mattai SA, Sallam T, Ortiz C, Lee EC, Robbins L, Ho S, Lee JE, Fisseha E, Shieh C, Sideri A, Shih DQ, Fleshner P, McGovern DP, Vu M, Hing TC, Bakirtzi K, Cheng M, Su B, Law I, Karagiannides I, Targan SR, Gallo RL, Li Z, Koon HW. Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. International journal of obesity (2005). 2016 September;40(9):1424-34. PubMed PMID: 27163748; PubMed Central PMCID: PMC5014693.

                  Million M, Larauche M. Stress, sex, and the enteric nervous system. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 September;28(9):1283-9. PubMed PMID: 27561694; PubMed Central PMCID: PMC5003424.

                  Padua D, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih D, Iliopoulos D, Pothoulakis C. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. American journal of physiology. Gastrointestinal and liver physiology. 2016 September 1;311(3):G446-57. PubMed PMID: 27492330; PubMed Central PMCID: PMC5076004.

                  Wang J, Sinnett-Smith J, Stevens JV, Young SH, Rozengurt E. Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD). The Journal of biological chemistry. 2016 August 19;291(34):17988-8005. PubMed PMID: 27369082; PubMed Central PMCID: PMC5016186.

                  Park SH, Videlock EJ, Shih W, Presson AP, Mayer EA, Chang L. Adverse childhood experiences are associated with irritable bowel syndrome and gastrointestinal symptom severity. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 August;28(8):1252-60. PubMed PMID: 27061107; PubMed Central PMCID: PMC4956522.

                  Antonios JP, Soto H, Everson RG, Orpilla J, Moughon D, Shin N, Sedighim S, Yong WH, Li G, Cloughesy TF, Liau LM, Prins RM. PD-1 blockade enhances the vaccination-induced immune response in glioma. JCI insight. 2016 July 7;1(10). PubMed PMID: 27453950; PubMed Central PMCID: PMC4951098.

                  Khalil HA, Lei NY, Brinkley G, Scott A, Wang J, Kar UK, Jabaji ZB, Lewis M, Martín MG, Dunn JC, Stelzner MG. A novel culture system for adult porcine intestinal crypts. Cell and tissue research. 2016 July;365(1):123-34. PubMed PMID: 26928041; PubMed Central PMCID: PMC4919165.

                  Videlock EJ, Shih W, Adeyemo M, Mahurkar-Joshi S, Presson AP, Polytarchou C, Alberto M, Iliopoulos D, Mayer EA, Chang L. The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression. Psychoneuroendocrinology. 2016 July;69:67-76. PubMed PMID: 27038676; PubMed Central PMCID: PMC4977028.

                  Kaji I, Akiba Y, Konno K, Watanabe M, Kimura S, Iwanaga T, Kuri A, Iwamoto K, Kuwahara A, Kaunitz JD. Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon. The Journal of physiology. 2016 June 15;594(12):3339-52. PubMed PMID: 26854275; PubMed Central PMCID: PMC4908031.

                  Holschneider DP, Guo Y, Mayer EA, Wang Z. Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats. Neurobiology of stress. 2016 June 1;3:8-22. PubMed PMID: 26751119; PubMed Central PMCID: PMC4700548.

                  Padua D, Vu JP, Germano PM, Pisegna JR. The Role of Neuropeptides in Mouse Models of Colitis. Journal of molecular neuroscience : MN. 2016 June;59(2):203-10. PubMed PMID: 26646243; PubMed Central PMCID: PMC4884658.

                  Scott A, Rouch JD, Jabaji Z, Khalil HA, Solorzano S, Lewis M, Martín MG, Stelzner MG, Dunn JC. Long-term renewable human intestinal epithelial stem cells as monolayers: A potential for clinical use. Journal of pediatric surgery. 2016 June;51(6):995-1000. PubMed PMID: 26995514; PubMed Central PMCID: PMC4921284.

                  Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. 2016 June;159(6):1520-1527. PubMed PMID: 26847803; PubMed Central PMCID: PMC4856542.

                  Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. American journal of physiology. Gastrointestinal and liver physiology. 2016 June 1;310(11):G1124-37. PubMed PMID: 27151939; PubMed Central PMCID: PMC5005285.

                  Yu J, Liu SH, Sanchez R, Nemunaitis J, Rozengurt E, Brunicardi FC. PDX1 associated therapy in translational medicine. Annals of translational medicine. 2016 June;4(11):214. PubMed PMID: 27386488; PubMed Central PMCID: PMC4916355.

                  Bakirtzi K, Law IK, Xue X, Iliopoulos D, Shah YM, Pothoulakis C. Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling. Journal of immunology (Baltimore, Md. : 1950). 2016 May 15;196(10):4311-21. PubMed PMID: 27076683; PubMed Central PMCID: PMC4868643.

                  Deriu E, Boxx GM, He X, Pan C, Benavidez SD, Cen L, Rozengurt N, Shi W, Cheng G. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS pathogens. 2016 May;12(5):e1005572. PubMed PMID: 27149619; PubMed Central PMCID: PMC4858270.

                  Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Molecular cancer research : MCR. 2016 May;14(5):437-47. PubMed PMID: 26979711; PubMed Central PMCID: PMC4867256.

                  Vorvis C, Koutsioumpa M, Iliopoulos D. Developments in miRNA gene signaling pathways in pancreatic cancer. Future oncology (London, England). 2016 May;12(9):1135-50. PubMed PMID: 26984178; PubMed Central PMCID: PMC5551925.

                  Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Science translational medicine. 2016 April 13;8(334):334ra54. PubMed PMID: 27075628; PubMed Central PMCID: PMC4934679.

                  Ackerman AL, Jellison FC, Lee UJ, Bradesi S, Rodríguez LV. The Glt1 glutamate receptor mediates the establishment and perpetuation of chronic visceral pain in an animal model of stress-induced bladder hyperalgesia. American journal of physiology. Renal physiology. 2016 April 1;310(7):F628-F636. PubMed PMID: 26697981; PubMed Central PMCID: PMC5504462.

                  Gupta A, Labus J, Kilpatrick LA, Bonyadi M, Ashe-McNalley C, Heendeniya N, Bradesi S, Chang L, Mayer EA. Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females. Brain structure & function. 2016 April;221(3):1667-79. PubMed PMID: 25630611; PubMed Central PMCID: PMC4573367.

                  Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly. International journal of antimicrobial agents. 2016 April;47(4):289-96. PubMed PMID: 27013001; PubMed Central PMCID: PMC4833571.

                  Wang J, Han L, Sinnett-Smith J, Han LL, Stevens JV, Rozengurt N, Young SH, Rozengurt E. Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552. American journal of physiology. Cell physiology. 2016 April 1;310(7):C542-57. PubMed PMID: 26739494; PubMed Central PMCID: PMC4824155.

                  Yuan PQ, Wu SV, Pothoulakis C, Taché Y. Urocortins and CRF receptor type 2 variants in the male rat colon: gene expression and regulation by endotoxin and anti-inflammatory effect. American journal of physiology. Gastrointestinal and liver physiology. 2016 March 15;310(6):G387-98. PubMed PMID: 26744472; PubMed Central PMCID: PMC4796293.

                  Hertzer KM, Xu M, Moro A, Dawson DW, Du L, Li G, Chang HH, Stark AP, Jung X, Hines OJ, Eibl G. Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer. Pancreas. 2016 March;45(3):458-65. PubMed PMID: 26495779; PubMed Central PMCID: PMC4854638.

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                  Law IK, Jensen D, Bunnett NW, Pothoulakis C. Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin. Scientific reports. 2016 February 23;6:22195. PubMed PMID: 26902265; PubMed Central PMCID: PMC4763298.

                  Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi K, Dulai GS, Machicado GA. Natural history of definitive diverticular hemorrhage based on stigmata of recent hemorrhage and colonoscopic Doppler blood flow monitoring for risk stratification and definitive hemostasis. Gastrointestinal endoscopy. 2016 February;83(2):416-23. PubMed PMID: 26227931; PubMed Central PMCID: PMC4715947.

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                  Birtolo C, Go VL, Ptasznik A, Eibl G, Pandol SJ. Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas. 2016 January;45(1):21-31. PubMed PMID: 26658038; PubMed Central PMCID: PMC4859755.

                  Camus M, Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi KA, Machicado GA, Dulai GS, Jensen ME, Gornbein JA. Comparison of Three Risk Scores to Predict Outcomes of Severe Lower Gastrointestinal Bleeding. Journal of clinical gastroenterology. 2016 January;50(1):52-8. PubMed PMID: 25599218; PubMed Central PMCID: PMC4504830.

                  Hoffman JM, Baritaki S, Ruiz JJ, Sideri A, Pothoulakis C. Corticotropin-Releasing Hormone Receptor 2 Signaling Promotes Mucosal Repair Responses after Colitis. The American journal of pathology. 2016 January;186(1):134-44. PubMed PMID: 26597886; PubMed Central PMCID: PMC4714033.

                  Hong JY, Naliboff B, Labus JS, Gupta A, Kilpatrick LA, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Mayer EA. Altered brain responses in subjects with irritable bowel syndrome during cued and uncued pain expectation. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 January;28(1):127-38. PubMed PMID: 26526698; PubMed Central PMCID: PMC4943658.

                  Jarcho JM, Feier NA, Labus JS, Naliboff B, Smith SR, Hong JY, Colloca L, Tillisch K, Mandelkern MA, Mayer EA, London ED. Placebo analgesia: Self-report measures and preliminary evidence of cortical dopamine release associated with placebo response. NeuroImage. Clinical. 2016;10:107-14. PubMed PMID: 26759785; PubMed Central PMCID: PMC4683423.

                  Jensen DM, Ohning GV, Kovacs TO, Ghassemi KA, Jutabha R, Dulai GS, Machicado GA. Doppler endoscopic probe as a guide to risk stratification and definitive hemostasis of peptic ulcer bleeding. Gastrointestinal endoscopy. 2016 January;83(1):129-36. PubMed PMID: 26318834; PubMed Central PMCID: PMC4691549.

                  Labus JS, Naliboff B, Kilpatrick L, Liu C, Ashe-McNalley C, dos Santos IR, Alaverdyan M, Woodworth D, Gupta A, Ellingson BM, Tillisch K, Mayer EA. Pain and Interoception Imaging Network (PAIN): A multimodal, multisite, brain-imaging repository for chronic somatic and visceral pain disorders. NeuroImage. 2016 January 1;124(Pt B):1232-7. PubMed PMID: 25902408; PubMed Central PMCID: PMC4627849.

                  Latorre R, Huynh J, Mazzoni M, Gupta A, Bonora E, Clavenzani P, Chang L, Mayer EA, De Giorgio R, Sternini C. Expression of the Bitter Taste Receptor, T2R38, in Enteroendocrine Cells of the Colonic Mucosa of Overweight/Obese vs. Lean Subjects. PloS one. 2016;11(2):e0147468. PubMed PMID: 26866366; PubMed Central PMCID: PMC4750998.

                  Moussaoui N, Larauche M, Biraud M, Molet J, Million M, Mayer E, Taché Y. Limited Nesting Stress Alters Maternal Behavior and In Vivo Intestinal Permeability in Male Wistar Pup Rats. PloS one. 2016;11(5):e0155037. PubMed PMID: 27149676; PubMed Central PMCID: PMC4858303.

                  Rouch JD, Scott A, Lei NY, Solorzano-Vargas RS, Wang J, Hanson EM, Kobayashi M, Lewis M, Stelzner MG, Dunn JC, Eckmann L, Martín MG. Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. PloS one. 2016;11(1):e0148216. PubMed PMID: 26820624; PubMed Central PMCID: PMC4731053.

                  Zhou G, Yu J, Wang A, Liu SH, Sinnett-Smith J, Wu J, Sanchez R, Nemunaitis J, Ricordi C, Rozengurt E, Brunicardi FC. Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma. Current molecular medicine. 2016;16(1):83-90. PubMed PMID: 26695692; PubMed Central PMCID: PMC4994969.

                  Vuong HE, Hardi CN, Barnes S, Brecha NC. Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 December 2;35(48):15955-70. PubMed PMID: 26631476; PubMed Central PMCID: PMC4666919.

                  Kilpatrick LA, Istrin JJ, Gupta A, Naliboff BD, Tillisch K, Labus JS, Mayer EA. Sex commonalities and differences in the relationship between resilient personality and the intrinsic connectivity of the salience and default mode networks. Biological psychology. 2015 December;112:107-15. PubMed PMID: 26440126; PubMed Central PMCID: PMC5012423.

                  Phan J, Benhammou JN, Pisegna JR. Gastric Hypersecretory States: Investigation and Management. Current treatment options in gastroenterology. 2015 December;13(4):386-97. PubMed PMID: 26342486; PubMed Central PMCID: PMC4633316.

                  Stark AP, Chang HH, Jung X, Moro A, Hertzer K, Xu M, Schmidt A, Hines OJ, Eibl G. E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice. Surgery. 2015 December;158(6):1564-72. PubMed PMID: 26297056; PubMed Central PMCID: PMC4637247.

                  Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of experimental medicine. 2015 November 16;212(12):2147-63. PubMed PMID: 26552708; PubMed Central PMCID: PMC4647265.

                  Chang HH, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G. Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1. American journal of physiology. Cell physiology. 2015 November 15;309(10):C639-49. PubMed PMID: 26310818; PubMed Central PMCID: PMC4652080.

                  Vu JP, Goyal D, Luong L, Oh S, Sandhu R, Norris J, Parsons W, Pisegna JR, Germano PM. PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin. American journal of physiology. Gastrointestinal and liver physiology. 2015 November 15;309(10):G816-25. PubMed PMID: 26336928; PubMed Central PMCID: PMC4652141.

                  Young SH, Rey O, Rozengurt E. Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: Impact of the highly conservative mutation Ser170Thr. Biochemical and biophysical research communications. 2015 November 6;467(1):1-6. PubMed PMID: 26431875; PubMed Central PMCID: PMC4613767.

                  Rodriguez JA, Huerta-Yepez S, Law IK, Baay-Guzman GJ, Tirado-Rodriguez B, Hoffman JM, Iliopoulos D, Hommes DW, Verspaget HW, Chang L, Pothoulakis C, Baritaki S. Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling. Cellular and molecular gastroenterology and hepatology. 2015 November 1;1(6):610-630. PubMed PMID: 26495412; PubMed Central PMCID: PMC4610032.

                  Vuong HE, Pérez de Sevilla Müller L, Hardi CN, McMahon DG, Brecha NC. Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines. Neuroscience. 2015 October 29;307:319-37. PubMed PMID: 26335381; PubMed Central PMCID: PMC4603663.

                  Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D. MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice. Gastroenterology. 2015 October;149(4):981-92.e11. PubMed PMID: 26055138; PubMed Central PMCID: PMC4584179.

                  Fang K, Sideri A, Law IK, Bakirtzi K, Polytarchou C, Iliopoulos D, Pothoulakis C. Identification of a novel substance P (SP)-neurokinin-1 receptor (NK-1R) microRNA-221-5p inflammatory network in human colonic epithelial cells. Cellular and molecular gastroenterology and hepatology. 2015 September 1;1(5):503-515. PubMed PMID: 26645045; PubMed Central PMCID: PMC4669978.

                  Hubbard CS, Hong J, Jiang Z, Ebrat B, Suyenobu B, Smith S, Heendeniya N, Naliboff BD, Tillisch K, Mayer EA, Labus JS. Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 September;27(9):1282-94. PubMed PMID: 26087779; PubMed Central PMCID: PMC4550526.

                  Cherukuri DP, Deignan JL, Das K, Grody WW, Herschman H. Instability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma. Molecular oncology. 2015 August;9(7):1252-8. PubMed PMID: 25817443; PubMed Central PMCID: PMC4523444.

                  Irimia A, Labus JS, Torgerson CM, Van Horn JD, Mayer EA. Altered viscerotopic cortical innervation in patients with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 August;27(8):1075-81. PubMed PMID: 25952540; PubMed Central PMCID: PMC4520752.

                  Kaunitz JD. The Discovery of PCR: ProCuRement of Divine Power. Digestive diseases and sciences. 2015 August;60(8):2230-1. PubMed PMID: 26077976; PubMed Central PMCID: PMC4501591.

                  Kobayashi M, Lei NY, Wang Q, Wu BM, Dunn JC. Orthogonally oriented scaffolds with aligned fibers for engineering intestinal smooth muscle. Biomaterials. 2015 August;61:75-84. PubMed PMID: 26001072; PubMed Central PMCID: PMC4464968.

                  Labus JS, Van Horn JD, Gupta A, Alaverdyan M, Torgerson C, Ashe-McNalley C, Irimia A, Hong JY, Naliboff B, Tillisch K, Mayer EA. Multivariate morphological brain signatures predict patients with chronic abdominal pain from healthy control subjects. Pain. 2015 August;156(8):1545-54. PubMed PMID: 25906347; PubMed Central PMCID: PMC4504800.

                  O'Mahony F, Wroblewski K, O'Byrne SM, Jiang H, Clerkin K, Benhammou J, Blaner WS, Beaven SW. Liver X receptors balance lipid stores in hepatic stellate cells through Rab18, a retinoid responsive lipid droplet protein. Hepatology (Baltimore, Md.). 2015 August;62(2):615-26. PubMed PMID: 25482505; PubMed Central PMCID: PMC4458237.

                  Tuominen I, Beaven SW. Intestinal farnesoid X receptor puts a fresh coat of wax on fatty liver. Hepatology (Baltimore, Md.). 2015 August;62(2):646-8. PubMed PMID: 25998695; PubMed Central PMCID: PMC4523235.

                  Law IK, Bakirtzi K, Polytarchou C, Oikonomopoulos A, Hommes D, Iliopoulos D, Pothoulakis C. Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis. Gut. 2015 July;64(7):1095-104. PubMed PMID: 25112884; PubMed Central PMCID: PMC4422787.

                  Lugea A, Waldron RT, Pandol SJ. Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2015 July;15(4 Suppl):S1-5. PubMed PMID: 25736240; PubMed Central PMCID: PMC4515411.

                  Stengel A, Karasawa H, Taché Y. The role of brain somatostatin receptor 2 in the regulation of feeding and drinking behavior. Hormones and behavior. 2015 July;73:15-22. PubMed PMID: 26026616; PubMed Central PMCID: PMC4546908.

                  Sanmiguel C, Gupta A, Mayer EA. Gut Microbiome and Obesity: A Plausible Explanation for Obesity. Current obesity reports. 2015 June;4(2):250-61. PubMed PMID: 26029487; PubMed Central PMCID: PMC4443745.

                  Vu JP, Larauche M, Flores M, Luong L, Norris J, Oh S, Liang LJ, Waschek J, Pisegna JR, Germano PM. Regulation of Appetite, Body Composition, and Metabolic Hormones by Vasoactive Intestinal Polypeptide (VIP). Journal of molecular neuroscience : MN. 2015 June;56(2):377-87. PubMed PMID: 25904310; PubMed Central PMCID: PMC4458420.

                  Gupta A, Rapkin AJ, Gill Z, Kilpatrick L, Fling C, Stains J, Masghati S, Tillisch K, Mayer EA, Labus JS. Disease-related differences in resting-state networks: a comparison between localized provoked vulvodynia, irritable bowel syndrome, and healthy control subjects. Pain. 2015 May;156(5):809-19. PubMed PMID: 25735001; PubMed Central PMCID: PMC4402252.

                  Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D. A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. Inflammatory bowel diseases. 2015 May;21(5):996-1005. PubMed PMID: 25738378; PubMed Central PMCID: PMC4402238.

                  Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JC, Martin MG, Lagasse E, Zhang L, Yu J. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Scientific reports. 2015 April 10;5:8566. PubMed PMID: 25858503; PubMed Central PMCID: PMC4392360.

                  Wu JX, Liu SH, Nemunaitis JJ, Brunicardi FC. Liposomal insulin promoter-thymidine kinase gene therapy followed by ganciclovir effectively ablates human pancreatic cancer in mice. Cancer letters. 2015 April 10;359(2):206-10. PubMed PMID: 25596375; PubMed Central PMCID: PMC4336837.

                  Akiba Y, Kaunitz JD, Million M. Peripheral corticotropin-releasing factor receptor type 2 activation increases colonic blood flow through nitric oxide pathway in rats. Digestive diseases and sciences. 2015 April;60(4):858-67. PubMed PMID: 25701320; PubMed Central PMCID: PMC4501405.

                  Anselmi L, Huynh J, Duraffourd C, Jaramillo I, Vegezzi G, Saccani F, Boschetti E, Brecha NC, De Giorgio R, Sternini C. Activation of μ opioid receptors modulates inflammation in acute experimental colitis. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 April;27(4):509-23. PubMed PMID: 25690069; PubMed Central PMCID: PMC4405133.

                  Liu Z, Sun F, Braun J, McGovern DP, Piantadosi S. Multilevel regularized regression for simultaneous taxa selection and network construction with metagenomic count data. Bioinformatics (Oxford, England). 2015 April 1;31(7):1067-74. PubMed PMID: 25416747; PubMed Central PMCID: PMC4382903.

                  Marvizon JC, Walwyn W, Minasyan A, Chen W, Taylor BK. Latent sensitization: a model for stress-sensitive chronic pain. Current protocols in neuroscience. 2015 April 1;71:9.50.1-14. PubMed PMID: 25829356; PubMed Central PMCID: PMC4532319.

                  Mayer EA, Gupta A, Kilpatrick LA, Hong JY. Imaging brain mechanisms in chronic visceral pain. Pain. 2015 April;156 Suppl 1:S50-63. PubMed PMID: 25789437; PubMed Central PMCID: PMC4428597.

                  Sideri A, Stavrakis D, Bowe C, Shih DQ, Fleshner P, Arsenescu V, Arsenescu R, Turner JR, Pothoulakis C, Karagiannides I. Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1. American journal of physiology. Gastrointestinal and liver physiology. 2015 April 1;308(7):G591-604. PubMed PMID: 25591865; PubMed Central PMCID: PMC4385897.

                  Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2. Molecular cancer therapeutics. 2015 April;14(4):1014-23. PubMed PMID: 25673820; PubMed Central PMCID: PMC4394038.

                  Tarling EJ, Ahn H, de Aguiar Vallim TQ. The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2. Arteriosclerosis, thrombosis, and vascular biology. 2015 April;35(4):787-95. PubMed PMID: 25593129; PubMed Central PMCID: PMC4376635.

                  Gukovsky I, Gukovskaya AS. Impaired autophagy triggers chronic pancreatitis: lessons from pancreas-specific atg5 knockout mice. Gastroenterology. 2015 March;148(3):501-5. PubMed PMID: 25613315; PubMed Central PMCID: PMC4443443.

                  Liu Y, Ji H, Zhang Y, Shen X, Gao F, He X, Li GA, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury. Journal of hepatology. 2015 March;62(3):563-72. PubMed PMID: 25450716; PubMed Central PMCID: PMC4336640.

                  Sakanaka T, Inoue T, Yorifuji N, Iguchi M, Fujiwara K, Narabayashi K, Kakimoto K, Nouda S, Okada T, Kuramoto T, Ishida K, Abe Y, Takeuchi T, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. The effects of a TGR5 agonist and a dipeptidyl peptidase IV inhibitor on dextran sulfate sodium-induced colitis in mice. Journal of gastroenterology and hepatology. 2015 March;30 Suppl 1:60-5. PubMed PMID: 25827806; PubMed Central PMCID: PMC4874188.

                  Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. The Journal of biological chemistry. 2015 February 27;290(9):5566-81. PubMed PMID: 25468909; PubMed Central PMCID: PMC4342471.

                  Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. Septin dynamics are essential for exocytosis. The Journal of biological chemistry. 2015 February 27;290(9):5280-97. PubMed PMID: 25575596; PubMed Central PMCID: PMC4342448.

                  Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell metabolism. 2015 February 3;21(2):334-46. PubMed PMID: 25651185; PubMed Central PMCID: PMC4349439.

                  de Aguiar Vallim TQ, Tarling EJ, Ahn H, Hagey LR, Romanoski CE, Lee RG, Graham MJ, Motohashi H, Yamamoto M, Edwards PA. MAFG is a transcriptional repressor of bile acid synthesis and metabolism. Cell metabolism. 2015 February 3;21(2):298-310. PubMed PMID: 25651182; PubMed Central PMCID: PMC4317590.

                  Bromley EG, May FP, Federer L, Spiegel BM, van Oijen MG. Explaining persistent under-use of colonoscopic cancer screening in African Americans: a systematic review. Preventive medicine. 2015 February;71:40-8. PubMed PMID: 25481094; PubMed Central PMCID: PMC4329030.

                  Kaji I, Iwanaga T, Watanabe M, Guth PH, Engel E, Kaunitz JD, Akiba Y. SCFA transport in rat duodenum. American journal of physiology. Gastrointestinal and liver physiology. 2015 February 1;308(3):G188-97. PubMed PMID: 25394661; PubMed Central PMCID: PMC4312951.

                  Nguyen AH, Toste PA, Farrell JJ, Clerkin BM, Williams J, Muthusamy VR, Watson RR, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Current recommendations for surveillance and surgery of intraductal papillary mucinous neoplasms may overlook some patients with cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2015 February;19(2):258-65. PubMed PMID: 25373706; PubMed Central PMCID: PMC4305480.

                  Tan YV, Abad C, Wang Y, Lopez R, Waschek J. VPAC2 (vasoactive intestinal peptide receptor type 2) receptor deficient mice develop exacerbated experimental autoimmune encephalomyelitis with increased Th1/Th17 and reduced Th2/Treg responses. Brain, behavior, and immunity. 2015 February;44:167-175. PubMed PMID: 25305591; PubMed Central PMCID: PMC4275378.

                  Taché Y, Million M. Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia. Journal of neurogastroenterology and motility. 2015 January 31;21(1):8-24. PubMed PMID: 25611064; PubMed Central PMCID: PMC4288101.

                  Coveleskie K, Gupta A, Kilpatrick LA, Mayer ED, Ashe-McNalley C, Stains J, Labus JS, Mayer EA. Altered functional connectivity within the central reward network in overweight and obese women. Nutrition & diabetes. 2015 January 19;5:e148. PubMed PMID: 25599560; PubMed Central PMCID: PMC4314578.

                  Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology. 2015 January 15;475:46-55. PubMed PMID: 25462345; PubMed Central PMCID: PMC4284078.

                  Abad C, Cheung-Lau G, Coûté-Monvoisin AC, Waschek JA. Vasoactive intestinal peptide-deficient mice exhibit reduced pathology in trinitrobenzene sulfonic acid-induced colitis. Neuroimmunomodulation. 2015;22(3):203-12. PubMed PMID: 25301381; PubMed Central PMCID: PMC4297532.

                  Bradesi S, Karagiannides I, Bakirtzi K, Joshi SM, Koukos G, Iliopoulos D, Pothoulakis C, Mayer EA. Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat. PloS one. 2015;10(7):e0130938. PubMed PMID: 26222740; PubMed Central PMCID: PMC4519289.

                  Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. Journal of Alzheimer's disease : JAD. 2015;43(3):967-76. PubMed PMID: 25125464; PubMed Central PMCID: PMC4258165.

                  Chen R, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM, Maitra A, Brentnall TA. Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. Laboratory investigation; a journal of technical methods and pathology. 2015 January;95(1):43-55. PubMed PMID: 25347153; PubMed Central PMCID: PMC4281293.

                  Cheng M, Ho S, Yoo JH, Tran DH, Bakirtzi K, Su B, Tran DH, Kubota Y, Ichikawa R, Koon HW. Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts. Clinical and experimental gastroenterology. 2015;8:13-29. PubMed PMID: 25565877; PubMed Central PMCID: PMC4274046.

                  Gupta A, Mayer EA, Sanmiguel CP, Van Horn JD, Woodworth D, Ellingson BM, Fling C, Love A, Tillisch K, Labus JS. Patterns of brain structural connectivity differentiate normal weight from overweight subjects. NeuroImage. Clinical. 2015;7:506-17. PubMed PMID: 25737959; PubMed Central PMCID: PMC4338207.

                  Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 January 1;21(1):157-65. PubMed PMID: 25348515; PubMed Central PMCID: PMC4286535.

                  Khalil HA, Lei NY, Nie W, Lewis MS, Stelzner MG, Martín MG, Dunn JC, Yoo J. Primary Myofibroblasts Maintain Short-Term Viability following Submucosal Injection in Syngeneic, Immune-Competent Mice Utilizing Murine Colonoscopy. PloS one. 2015;10(5):e0127258. PubMed PMID: 26016485; PubMed Central PMCID: PMC4445916.

                  Kutch JJ, Yani MS, Asavasopon S, Kirages DJ, Rana M, Cosand L, Labus JS, Kilpatrick LA, Ashe-McNalley C, Farmer MA, Johnson KA, Ness TJ, Deutsch G, Harris RE, Apkarian AV, Clauw DJ, Mackey SC, Mullins C, Mayer EA. Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study. NeuroImage. Clinical. 2015;8:493-502. PubMed PMID: 26106574; PubMed Central PMCID: PMC4474411.

                  Law IK, Pothoulakis C. MicroRNA-133α regulates neurotensin-associated colonic inflammation in colonic epithelial cells and experimental colitis. RNA & disease (Houston, Tex.). 2015;2(1). PubMed PMID: 26005712; PubMed Central PMCID: PMC4441413.

                  Li Y, Go VL, Sarkar FH. The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome. Pancreas. 2015 January;44(1):1-10. PubMed PMID: 25493373; PubMed Central PMCID: PMC4264839.

                  Martinez L, Ermolova NV, Ishikawa TO, Stout DB, Herschman HR, Spencer MJ. A reporter mouse for optical imaging of inflammation in mdx muscles. Skeletal muscle. 2015;5:15. PubMed PMID: 25949789; PubMed Central PMCID: PMC4422315.

                  Marzagalli R, Scuderi S, Drago F, Waschek JA, Castorina A. Emerging Role of PACAP as a New Potential Therapeutic Target in Major Diabetes Complications. International journal of endocrinology. 2015;2015:160928. PubMed PMID: 26074958; PubMed Central PMCID: PMC4446501.

                  McGowan I, Anton PA, Elliott J, Cranston RD, Duffill K, Althouse AD, Hawkins KL, De Rosa SC. Exploring the feasibility of multi-site flow cytometric processing of gut associated lymphoid tissue with centralized data analysis for multi-site clinical trials. PloS one. 2015;10(5):e0126454. PubMed PMID: 26010577; PubMed Central PMCID: PMC4444258.

                  Mulak A, Larauche M, Biraud M, Million M, Rivier J, Taché Y. Selective agonists of somatostatin receptor subtype 1 or 2 injected peripherally induce antihyperalgesic effect in two models of visceral hypersensitivity in mice. Peptides. 2015 January;63:71-80. PubMed PMID: 25451334; PubMed Central PMCID: PMC4385413.

                  Orand A, Gupta A, Shih W, Presson AP, Hammer C, Niesler B, Heendeniya N, Mayer EA, Chang L. Catecholaminergic Gene Polymorphisms Are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome. PloS one. 2015;10(8):e0135910. PubMed PMID: 26288143; PubMed Central PMCID: PMC4546052.

                  Taché Y. Corticotrophin-releasing factor 1 activation in the central amygdale and visceral hyperalgesia. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 January;27(1):1-6. PubMed PMID: 25557223; PubMed Central PMCID: PMC4389773.

                  Wang L, Mogami S, Yakabi S, Karasawa H, Yamada C, Yakabi K, Hattori T, Taché Y. Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito. PloS one. 2015;10(9):e0139325. PubMed PMID: 26421719; PubMed Central PMCID: PMC4589401.

                  Wang Y, Yan C, Liu L, Wang W, Du H, Fan W, Lutfy K, Jiang M, Friedman TC, Liu Y. 11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue. American journal of physiology. Endocrinology and metabolism. 2015 January 1;308(1):E84-95. PubMed PMID: 25389364; PubMed Central PMCID: PMC4281684.

                  Yoo JH, Ho S, Tran DH, Cheng M, Bakirtzi K, Kukota Y, Ichikawa R, Su B, Tran DH, Hing TC, Chang I, Shih DQ, Issacson RE, Gallo RL, Fiocchi C, Pothoulakis C, Koon HW. Anti-fibrogenic effects of the anti-microbial peptide cathelicidin in murine colitis-associated fibrosis. Cellular and molecular gastroenterology and hepatology. 2015 January;1(1):55-74.e1. PubMed PMID: 25729764; PubMed Central PMCID: PMC4338438.

                  Zhu J, Lu T, Yue S, Shen X, Gao F, Busuttil RW, Kupiec-Weglinski JW, Xia Q, Zhai Y. Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation. Transplantation. 2015 January;99(1):48-55. PubMed PMID: 25340604; PubMed Central PMCID: PMC4272660.

                  Akiba Y, Kaunitz JD. Prostaglandin pathways in duodenal chemosensing. Journal of gastroenterology and hepatology. 2014 December;29 Suppl 4:93-8. PubMed PMID: 25521740; PubMed Central PMCID: PMC4451058.

                  Bagarinao E, Johnson KA, Martucci KT, Ichesco E, Farmer MA, Labus J, Ness TJ, Harris R, Deutsch G, Apkarian AV, Mayer EA, Clauw DJ, Mackey S. Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network study. Pain. 2014 December;155(12):2502-9. PubMed PMID: 25242566; PubMed Central PMCID: PMC4504202.

                  Buzzanco A, Gomez A, Rodriguez E, French BA, Tillman BA, Chang S, Ganapathy E, Junrungsee S, Zarrinpar A, Agopian VG, Naini BV, French SW Jr, French SW Sr. Digital quantitation of HCC-associated stem cell markers and protein quality control factors using tissue arrays of human liver sections. Experimental and molecular pathology. 2014 December;97(3):399-410. PubMed PMID: 25218810; PubMed Central PMCID: PMC4262606.

                  Donahue TR, Nguyen AH, Moughan J, Li L, Tatishchev S, Toste P, Farrell JJ. Stromal microRNA-21 levels predict response to 5-fluorouracil in patients with pancreatic cancer. Journal of surgical oncology. 2014 December;110(8):952-9. PubMed PMID: 25132574; PubMed Central PMCID: PMC4232442.

                  Ji H, Liu Y, Zhang Y, Shen XD, Gao F, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. T-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury. Hepatology (Baltimore, Md.). 2014 December;60(6):2052-2064. PubMed PMID: 25066922; PubMed Central PMCID: PMC4396987.

                  Karasawa H, Pietra C, Giuliano C, Garcia-Rubio S, Xu X, Yakabi S, Taché Y, Wang L. New ghrelin agonist, HM01 alleviates constipation and L-dopa-delayed gastric emptying in 6-hydroxydopamine rat model of Parkinson's disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 December;26(12):1771-82. PubMed PMID: 25327342; PubMed Central PMCID: PMC4457321.

                  Stengel A, Taché Y. Brain peptides and the modulation of postoperative gastric ileus. Current opinion in pharmacology. 2014 December;19:31-7. PubMed PMID: 24999843; PubMed Central PMCID: PMC4254047.

                  Wagner JP, Sullins VF, Dunn JC. Skin-derived precursors generate enteric-type neurons in aganglionic jejunum. Journal of pediatric surgery. 2014 December;49(12):1809-14. PubMed PMID: 25487489; PubMed Central PMCID: PMC4261145.

                  Wagner JP, Sullins VF, Khalil HA, Dunn JC. A durable model of Hirschsprung's colon. Journal of pediatric surgery. 2014 December;49(12):1804-8. PubMed PMID: 25487488; PubMed Central PMCID: PMC4261142.

                  Hong C, Marshall SM, McDaniel AL, Graham M, Layne JD, Cai L, Scotti E, Boyadjian R, Kim J, Chamberlain BT, Tangirala RK, Jung ME, Fong L, Lee R, Young SG, Temel RE, Tontonoz P. The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice. Cell metabolism. 2014 November 4;20(5):910-8. PubMed PMID: 25440061; PubMed Central PMCID: PMC4261644.

                  Tong M, Jacobs JP, McHardy IH, Braun J. Sampling of intestinal microbiota and targeted amplification of bacterial 16S rRNA genes for microbial ecologic analysis. Current protocols in immunology. 2014 November 3;107:7.41.1-11. PubMed PMID: 25367129; PubMed Central PMCID: PMC4457454.

                  Balaji K, French CT, Miller JF, Colicelli J. The RAB5-GEF function of RIN1 regulates multiple steps during Listeria monocytogenes infection. Traffic (Copenhagen, Denmark). 2014 November;15(11):1206-18. PubMed PMID: 25082076; PubMed Central PMCID: PMC4282165.

                  Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR. Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. Molecular cancer research : MCR. 2014 November;12(11):1677-88. PubMed PMID: 25063587; PubMed Central PMCID: PMC4233191.

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                  Shih DQ, Zheng L, Zhang X, Zhang H, Kanazawa Y, Ichikawa R, Wallace KL, Chen J, Pothoulakis C, Koon HW, Targan SR. Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis. Mucosal immunology. 2014 November;7(6):1492-503. PubMed PMID: 24850426; PubMed Central PMCID: PMC4205266.

                  Spiegel BM, Hays RD, Bolus R, Melmed GY, Chang L, Whitman C, Khanna PP, Paz SH, Hays T, Reise S, Khanna D. Development of the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) gastrointestinal symptom scales. The American journal of gastroenterology. 2014 November;109(11):1804-14. PubMed PMID: 25199473; PubMed Central PMCID: PMC4285435.

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                  Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Molecular cancer therapeutics. 2014 October;13(10):2303-14. PubMed PMID: 25082960; PubMed Central PMCID: PMC4188417.

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                  Arnold AP. Conceptual frameworks and mouse models for studying sex differences in physiology and disease: why compensation changes the game. Experimental neurology. 2014 September;259:2-9. PubMed PMID: 24509348; PubMed Central PMCID: PMC4125548.

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                  Koon HW, Ho S, Hing TC, Cheng M, Chen X, Ichikawa Y, Kelly CP, Pothoulakis C. Fidaxomicin inhibits Clostridium difficile toxin A-mediated enteritis in the mouse ileum. Antimicrobial agents and chemotherapy. 2014 August;58(8):4642-50. PubMed PMID: 24890583; PubMed Central PMCID: PMC4135997.

                  Ngun TC, Ghahramani NM, Creek MM, Williams-Burris SM, Barseghyan H, Itoh Y, Sánchez FJ, McClusky R, Sinsheimer JS, Arnold AP, Vilain E. Feminized behavior and brain gene expression in a novel mouse model of Klinefelter Syndrome. Archives of sexual behavior. 2014 August;43(6):1043-57. PubMed PMID: 24923877; PubMed Central PMCID: PMC4371776.

                  Viitasalo L, Niemi L, Ashorn M, Ashorn S, Braun J, Huhtala H, Collin P, Mäki M, Kaukinen K, Kurppa K, Iltanen S. Early microbial markers of celiac disease. Journal of clinical gastroenterology. 2014 August;48(7):620-4. PubMed PMID: 24518796; PubMed Central PMCID: PMC4082475.

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                  Lin L, Ma C, Wei B, Aziz N, Rajalingam R, Yusung S, Erlich HA, Trachtenberg EA, Targan SR, McGovern DP, Heath JR, Braun J. Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function. Journal of immunology (Baltimore, Md. : 1950). 2014 July 15;193(2):940-9. PubMed PMID: 24935928; PubMed Central PMCID: PMC4096688.

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                  Inoue T, Higashiyama M, Kaji I, Rudenkyy S, Higuchi K, Guth PH, Engel E, Kaunitz JD, Akiba Y. Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats. Digestive diseases and sciences. 2014 June;59(6):1286-95. PubMed PMID: 24379150; PubMed Central PMCID: PMC4196264.

                  Sallam T, Ito A, Rong X, Kim J, van Stijn C, Chamberlain BT, Jung ME, Chao LC, Jones M, Gilliland T, Wu X, Su GL, Tangirala RK, Tontonoz P, Hong C. The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis. Journal of lipid research. 2014 June;55(6):1120-30. PubMed PMID: 24671012; PubMed Central PMCID: PMC4031943.

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                  Kilpatrick LA, Coveleskie K, Connolly L, Labus JS, Ebrat B, Stains J, Jiang Z, Suyenobu BY, Raybould HE, Tillisch K, Mayer EA. Influence of sucrose ingestion on brainstem and hypothalamic intrinsic oscillations in lean and obese women. Gastroenterology. 2014 May;146(5):1212-21. PubMed PMID: 24480616; PubMed Central PMCID: PMC4113508.

                  Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle. Virology. 2014 April;454-455:118-27. PubMed PMID: 24725938; PubMed Central PMCID: PMC4011396.

                  Mulak A, Taché Y, Larauche M. Sex hormones in the modulation of irritable bowel syndrome. World journal of gastroenterology. 2014 March 14;20(10):2433-48. PubMed PMID: 24627581; PubMed Central PMCID: PMC3949254.

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                  Abad C, Nobuta H, Li J, Kasai A, Yong WH, Waschek JA. Targeted STAT3 disruption in myeloid cells alters immunosuppressor cell abundance in a murine model of spontaneous medulloblastoma. Journal of leukocyte biology. 2014 February;95(2):357-67. PubMed PMID: 24068730; PubMed Central PMCID: PMC3896661.

                  Goebel-Stengel M, Stengel A, Wang L, Taché Y. Orexigenic response to tail pinch: role of brain NPY(1) and corticotropin releasing factor receptors. American journal of physiology. Regulatory, integrative and comparative physiology. 2014 February 1;306(3):R164-74. PubMed PMID: 24338440; PubMed Central PMCID: PMC3921301.

                  Young SH, Rey O, Sinnett-Smith J, Rozengurt E. Intracellular Ca2+ oscillations generated via the Ca2+-sensing receptor are mediated by negative feedback by PKCα at Thr888. American journal of physiology. Cell physiology. 2014 February 1;306(3):C298-306. PubMed PMID: 24336654; PubMed Central PMCID: PMC3919994.

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                  Duraffourd C, Kumala E, Anselmi L, Brecha NC, Sternini C. Opioid-induced mitogen-activated protein kinase signaling in rat enteric neurons following chronic morphine treatment. PloS one. 2014;9(10):e110230. PubMed PMID: 25302800; PubMed Central PMCID: PMC4193881.

                  Edderkaoui M, Eibl G. Risk factors for pancreatic cancer: underlying mechanisms and potential targets. Frontiers in physiology. 2014;5:490. PubMed PMID: 25540626; PubMed Central PMCID: PMC4261721.

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                  Gong J, Robbins LA, Lugea A, Waldron RT, Jeon CY, Pandol SJ. Diabetes, pancreatic cancer, and metformin therapy. Frontiers in physiology. 2014;5:426. PubMed PMID: 25426078; PubMed Central PMCID: PMC4224068.

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                  Karagiannides I, Golovatscka V, Bakirtzi K, Sideri A, Salas M, Stavrakis D, Polytarchou C, Iliopoulos D, Pothoulakis C, Bradesi S. Chronic unpredictable stress regulates visceral adipocyte-mediated glucose metabolism and inflammatory circuits in male rats. Physiological reports. 2014;2(5):e00284. PubMed PMID: 24819750; PubMed Central PMCID: PMC4098730.

                  Labus JS, Dinov ID, Jiang Z, Ashe-McNalley C, Zamanyan A, Shi Y, Hong JY, Gupta A, Tillisch K, Ebrat B, Hobel S, Gutman BA, Joshi S, Thompson PM, Toga AW, Mayer EA. Irritable bowel syndrome in female patients is associated with alterations in structural brain networks. Pain. 2014 January;155(1):137-49. PubMed PMID: 24076048; PubMed Central PMCID: PMC4100785.

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                  Ming M, Sinnett-Smith J, Wang J, Soares HP, Young SH, Eibl G, Rozengurt E. Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. PloS one. 2014;9(12):e114573. PubMed PMID: 25493642; PubMed Central PMCID: PMC4262417.

                  Richardson-Harman N, Hendrix CW, Bumpus NN, Mauck C, Cranston RD, Yang K, Elliott J, Tanner K, McGowan I, Kashuba A, Anton PA. Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study. PloS one. 2014;9(10):e111507. PubMed PMID: 25350130; PubMed Central PMCID: PMC4211741.

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                  Stengel A, Taché Y. CRF and urocortin peptides as modulators of energy balance and feeding behavior during stress. Frontiers in neuroscience. 2014;8:52. PubMed PMID: 24672423; PubMed Central PMCID: PMC3957495.

                  Su AM, Shih W, Presson AP, Chang L. Characterization of symptoms in irritable bowel syndrome with mixed bowel habit pattern. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 January;26(1):36-45. PubMed PMID: 23991913; PubMed Central PMCID: PMC3865067.

                  Vegezzi G, Anselmi L, Huynh J, Barocelli E, Rozengurt E, Raybould H, Sternini C. Diet-induced regulation of bitter taste receptor subtypes in the mouse gastrointestinal tract. PloS one. 2014;9(9):e107732. PubMed PMID: 25238152; PubMed Central PMCID: PMC4169553.

                  Vu JP, Million M, Larauche M, Luong L, Norris J, Waschek JA, Pothoulakis C, Pisegna JR, Germano PM. Inhibition of vasoactive intestinal polypeptide (VIP) induces resistance to dextran sodium sulfate (DSS)-induced colitis in mice. Journal of molecular neuroscience : MN. 2014 January;52(1):37-47. PubMed PMID: 24395090; PubMed Central PMCID: PMC4114158.

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                  Ke B, Shen XD, Zhang Y, Ji H, Gao F, Yue S, Kamo N, Zhai Y, Yamamoto M, Busuttil RW, Kupiec-Weglinski JW. KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants. Journal of hepatology. 2013 December;59(6):1200-7. PubMed PMID: 23867319; PubMed Central PMCID: PMC4524560.

                  Marcus EA, Vagin O, Tokhtaeva E, Sachs G, Scott DR. Helicobacter pylori impedes acid-induced tightening of gastric epithelial junctions. American journal of physiology. Gastrointestinal and liver physiology. 2013 November 15;305(10):G731-9. PubMed PMID: 23989011; PubMed Central PMCID: PMC3840231.

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                  Rozengurt E, Sinnett-Smith J, Kisfalvi K. Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2010 May 1;16(9):2505-11. PubMed PMID: 20388847; PubMed Central PMCID: PMC2862089.

                  Weinberg BM, Spiegel BM, Tomlinson JS, Farrell JJ. Asymptomatic pancreatic cystic neoplasms: maximizing survival and quality of life using Markov-based clinical nomograms. Gastroenterology. 2010 February;138(2):531-40. PubMed PMID: 19818780; PubMed Central PMCID: PMC2949077.

                  Torres-Marquez E, Sinnett-Smith J, Guha S, Kui R, Waldron RT, Rey O, Rozengurt E. CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway. Biochemical and biophysical research communications. 2010 January 1;391(1):63-8. PubMed PMID: 19896460; PubMed Central PMCID: PMC2812606.

                  Correction: A Novel Small-Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In vitro and In vivo. Molecular cancer therapeutics. 2010. PubMed Central PMCID: PMC2940835.

                  Jiang X, Sinnett-Smith J, Rozengurt E. Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. Biochemical and biophysical research communications. 2009 September 25;387(3):521-4. PubMed PMID: 19615971; PubMed Central PMCID: PMC2754135.

                  Kisfalvi K, Eibl G, Sinnett-Smith J, Rozengurt E. Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer research. 2009 August 15;69(16):6539-45. PubMed PMID: 19679549; PubMed Central PMCID: PMC2753241.

                  Spiegel BM, Farid M, van Oijen MG, Laine L, Howden CW, Esrailian E. Adherence to best practice guidelines in dyspepsia: a survey comparing dyspepsia experts, community gastroenterologists and primary-care providers. Alimentary pharmacology & therapeutics. 2009 April 15;29(8):871-81. PubMed PMID: 19183152; PubMed Central PMCID: PMC2953468.

                  Desai AA, Bolus R, Nissenson A, Chertow GM, Bolus S, Solomon MD, Khawar OS, Talley J, Spiegel BM. Is there "cherry picking" in the ESRD Program? Perceptions from a Dialysis Provider Survey. Clinical journal of the American Society of Nephrology : CJASN. 2009 April;4(4):772-7. PubMed PMID: 19339407; PubMed Central PMCID: PMC2666440.

                  Spiegel BM, Chey WD, Chang L. Bacterial overgrowth and irritable bowel syndrome: unifying hypothesis or a spurious consequence of proton pump inhibitors?. The American journal of gastroenterology. 2008 December;103(12):2972-6. PubMed PMID: 19086951; PubMed Central PMCID: PMC2949084.

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                  Rozengurt E, Sternini C. Taste receptor signaling in the mammalian gut. Current opinion in pharmacology. 2007 December;7(6):557-62. PubMed PMID: 18024184; PubMed Central PMCID: PMC2753238.

                  McConalogue K, Grady EF, Minnis J, Balestra B, Tonini M, Brecha NC, Bunnett NW, Sternini C. Activation and internalization of the mu-opioid receptor by the newly discovered endogenous agonists, endomorphin-1 and endomorphin-2. Neuroscience. 1999 March;90(3):1051-9. PubMed PMID: 10218804; PubMed Central PMCID: PMC4472477

  Condro MC, Matynia A, Foster NN, Ago Y, Rajbhandari AK, Van C, Jayaram B, Parikh S, Diep AL, Nguyen E, May V, Dong HW, Waschek JA. High-resolution characterization of a PACAP-EGFP transgenic mouse model for mapping PACAP-expressing neurons. The Journal of comparative neurology. 2016 December 15;524(18):3827-3848. PubMed PMID: 27197019; PubMed Central PMCID: PMC5063673.

                  Duboc H, Tolstanova G, Yuan PQ, Wu V, Kaji I, Biraud M, Akiba Y, Kaunitz J, Million M, Tache Y, Larauche M. Reduction of epithelial secretion in male rat distal colonic mucosa by bile acid receptor TGR5 agonist, INT-777: role of submucosal neurons. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 November;28(11):1663-1676. PubMed PMID: 27259385; PubMed Central PMCID: PMC5083223.

                  Orand A, Naliboff B, Gadd M, Shih W, Ju T, Presson AP, Mayer EA, Chang L. Corticotropin-releasing hormone receptor 1 (CRH-R1) polymorphisms are associated with irritable bowel syndrome and acoustic startle response. Psychoneuroendocrinology. 2016 November;73:133-141. PubMed PMID: 27497153; PubMed Central PMCID: PMC5048544.

                  Koon HW, Su B, Xu C, Mussatto CC, Tran DH, Lee EC, Ortiz C, Wang J, Lee JE, Ho S, Chen X, Kelly CP, Pothoulakis C. Probiotic Saccharomyces boulardii CNCM I-745 prevents outbreak-associated Clostridium difficile-associated cecal inflammation in hamsters. American journal of physiology. Gastrointestinal and liver physiology. 2016 October 1;311(4):G610-G623. PubMed PMID: 27514478; PubMed Central PMCID: PMC5142203.

                  Hoang-Yen Tran D, Hoang-Ngoc Tran D, Mattai SA, Sallam T, Ortiz C, Lee EC, Robbins L, Ho S, Lee JE, Fisseha E, Shieh C, Sideri A, Shih DQ, Fleshner P, McGovern DP, Vu M, Hing TC, Bakirtzi K, Cheng M, Su B, Law I, Karagiannides I, Targan SR, Gallo RL, Li Z, Koon HW. Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. International journal of obesity (2005). 2016 September;40(9):1424-34. PubMed PMID: 27163748; PubMed Central PMCID: PMC5014693.

                  Million M, Larauche M. Stress, sex, and the enteric nervous system. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 September;28(9):1283-9. PubMed PMID: 27561694; PubMed Central PMCID: PMC5003424.

                  Padua D, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih D, Iliopoulos D, Pothoulakis C. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. American journal of physiology. Gastrointestinal and liver physiology. 2016 September 1;311(3):G446-57. PubMed PMID: 27492330; PubMed Central PMCID: PMC5076004.

                  Wang J, Sinnett-Smith J, Stevens JV, Young SH, Rozengurt E. Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD). The Journal of biological chemistry. 2016 August 19;291(34):17988-8005. PubMed PMID: 27369082; PubMed Central PMCID: PMC5016186.

                  Park SH, Videlock EJ, Shih W, Presson AP, Mayer EA, Chang L. Adverse childhood experiences are associated with irritable bowel syndrome and gastrointestinal symptom severity. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 August;28(8):1252-60. PubMed PMID: 27061107; PubMed Central PMCID: PMC4956522.

                  Antonios JP, Soto H, Everson RG, Orpilla J, Moughon D, Shin N, Sedighim S, Yong WH, Li G, Cloughesy TF, Liau LM, Prins RM. PD-1 blockade enhances the vaccination-induced immune response in glioma. JCI insight. 2016 July 7;1(10). PubMed PMID: 27453950; PubMed Central PMCID: PMC4951098.

                  Khalil HA, Lei NY, Brinkley G, Scott A, Wang J, Kar UK, Jabaji ZB, Lewis M, Martín MG, Dunn JC, Stelzner MG. A novel culture system for adult porcine intestinal crypts. Cell and tissue research. 2016 July;365(1):123-34. PubMed PMID: 26928041; PubMed Central PMCID: PMC4919165.

                  Videlock EJ, Shih W, Adeyemo M, Mahurkar-Joshi S, Presson AP, Polytarchou C, Alberto M, Iliopoulos D, Mayer EA, Chang L. The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression. Psychoneuroendocrinology. 2016 July;69:67-76. PubMed PMID: 27038676; PubMed Central PMCID: PMC4977028.

                  Kaji I, Akiba Y, Konno K, Watanabe M, Kimura S, Iwanaga T, Kuri A, Iwamoto K, Kuwahara A, Kaunitz JD. Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon. The Journal of physiology. 2016 June 15;594(12):3339-52. PubMed PMID: 26854275; PubMed Central PMCID: PMC4908031.

                  Holschneider DP, Guo Y, Mayer EA, Wang Z. Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats. Neurobiology of stress. 2016 June 1;3:8-22. PubMed PMID: 26751119; PubMed Central PMCID: PMC4700548.

                  Padua D, Vu JP, Germano PM, Pisegna JR. The Role of Neuropeptides in Mouse Models of Colitis. Journal of molecular neuroscience : MN. 2016 June;59(2):203-10. PubMed PMID: 26646243; PubMed Central PMCID: PMC4884658.

                  Scott A, Rouch JD, Jabaji Z, Khalil HA, Solorzano S, Lewis M, Martín MG, Stelzner MG, Dunn JC. Long-term renewable human intestinal epithelial stem cells as monolayers: A potential for clinical use. Journal of pediatric surgery. 2016 June;51(6):995-1000. PubMed PMID: 26995514; PubMed Central PMCID: PMC4921284.

                  Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. 2016 June;159(6):1520-1527. PubMed PMID: 26847803; PubMed Central PMCID: PMC4856542.

                  Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. American journal of physiology. Gastrointestinal and liver physiology. 2016 June 1;310(11):G1124-37. PubMed PMID: 27151939; PubMed Central PMCID: PMC5005285.

                  Yu J, Liu SH, Sanchez R, Nemunaitis J, Rozengurt E, Brunicardi FC. PDX1 associated therapy in translational medicine. Annals of translational medicine. 2016 June;4(11):214. PubMed PMID: 27386488; PubMed Central PMCID: PMC4916355.

                  Bakirtzi K, Law IK, Xue X, Iliopoulos D, Shah YM, Pothoulakis C. Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling. Journal of immunology (Baltimore, Md. : 1950). 2016 May 15;196(10):4311-21. PubMed PMID: 27076683; PubMed Central PMCID: PMC4868643.

                  Deriu E, Boxx GM, He X, Pan C, Benavidez SD, Cen L, Rozengurt N, Shi W, Cheng G. Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons. PLoS pathogens. 2016 May;12(5):e1005572. PubMed PMID: 27149619; PubMed Central PMCID: PMC4858270.

                  Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Molecular cancer research : MCR. 2016 May;14(5):437-47. PubMed PMID: 26979711; PubMed Central PMCID: PMC4867256.

                  Vorvis C, Koutsioumpa M, Iliopoulos D. Developments in miRNA gene signaling pathways in pancreatic cancer. Future oncology (London, England). 2016 May;12(9):1135-50. PubMed PMID: 26984178; PubMed Central PMCID: PMC5551925.

                  Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Science translational medicine. 2016 April 13;8(334):334ra54. PubMed PMID: 27075628; PubMed Central PMCID: PMC4934679.

                  Ackerman AL, Jellison FC, Lee UJ, Bradesi S, Rodríguez LV. The Glt1 glutamate receptor mediates the establishment and perpetuation of chronic visceral pain in an animal model of stress-induced bladder hyperalgesia. American journal of physiology. Renal physiology. 2016 April 1;310(7):F628-F636. PubMed PMID: 26697981; PubMed Central PMCID: PMC5504462.

                  Gupta A, Labus J, Kilpatrick LA, Bonyadi M, Ashe-McNalley C, Heendeniya N, Bradesi S, Chang L, Mayer EA. Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females. Brain structure & function. 2016 April;221(3):1667-79. PubMed PMID: 25630611; PubMed Central PMCID: PMC4573367.

                  Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly. International journal of antimicrobial agents. 2016 April;47(4):289-96. PubMed PMID: 27013001; PubMed Central PMCID: PMC4833571.

                  Wang J, Han L, Sinnett-Smith J, Han LL, Stevens JV, Rozengurt N, Young SH, Rozengurt E. Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552. American journal of physiology. Cell physiology. 2016 April 1;310(7):C542-57. PubMed PMID: 26739494; PubMed Central PMCID: PMC4824155.

                  Yuan PQ, Wu SV, Pothoulakis C, Taché Y. Urocortins and CRF receptor type 2 variants in the male rat colon: gene expression and regulation by endotoxin and anti-inflammatory effect. American journal of physiology. Gastrointestinal and liver physiology. 2016 March 15;310(6):G387-98. PubMed PMID: 26744472; PubMed Central PMCID: PMC4796293.

                  Hertzer KM, Xu M, Moro A, Dawson DW, Du L, Li G, Chang HH, Stark AP, Jung X, Hines OJ, Eibl G. Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer. Pancreas. 2016 March;45(3):458-65. PubMed PMID: 26495779; PubMed Central PMCID: PMC4854638.

                  Mahurkar S, Polytarchou C, Iliopoulos D, Pothoulakis C, Mayer EA, Chang L. Genome-wide DNA methylation profiling of peripheral blood mononuclear cells in irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 March;28(3):410-22. PubMed PMID: 26670691; PubMed Central PMCID: PMC4760882.

                  Law IK, Jensen D, Bunnett NW, Pothoulakis C. Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin. Scientific reports. 2016 February 23;6:22195. PubMed PMID: 26902265; PubMed Central PMCID: PMC4763298.

                  Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi K, Dulai GS, Machicado GA. Natural history of definitive diverticular hemorrhage based on stigmata of recent hemorrhage and colonoscopic Doppler blood flow monitoring for risk stratification and definitive hemostasis. Gastrointestinal endoscopy. 2016 February;83(2):416-23. PubMed PMID: 26227931; PubMed Central PMCID: PMC4715947.

                  Walwyn WM, Chen W, Kim H, Minasyan A, Ennes HS, McRoberts JA, Marvizón JC. Sustained Suppression of Hyperalgesia during Latent Sensitization by μ-, δ-, and κ-opioid receptors and α2A Adrenergic Receptors: Role of Constitutive Activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2016 January 6;36(1):204-21. PubMed PMID: 26740662; PubMed Central PMCID: PMC4701961.

                  Birtolo C, Go VL, Ptasznik A, Eibl G, Pandol SJ. Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas. 2016 January;45(1):21-31. PubMed PMID: 26658038; PubMed Central PMCID: PMC4859755.

                  Camus M, Jensen DM, Ohning GV, Kovacs TO, Jutabha R, Ghassemi KA, Machicado GA, Dulai GS, Jensen ME, Gornbein JA. Comparison of Three Risk Scores to Predict Outcomes of Severe Lower Gastrointestinal Bleeding. Journal of clinical gastroenterology. 2016 January;50(1):52-8. PubMed PMID: 25599218; PubMed Central PMCID: PMC4504830.

                  Hoffman JM, Baritaki S, Ruiz JJ, Sideri A, Pothoulakis C. Corticotropin-Releasing Hormone Receptor 2 Signaling Promotes Mucosal Repair Responses after Colitis. The American journal of pathology. 2016 January;186(1):134-44. PubMed PMID: 26597886; PubMed Central PMCID: PMC4714033.

                  Hong JY, Naliboff B, Labus JS, Gupta A, Kilpatrick LA, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Mayer EA. Altered brain responses in subjects with irritable bowel syndrome during cued and uncued pain expectation. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2016 January;28(1):127-38. PubMed PMID: 26526698; PubMed Central PMCID: PMC4943658.

                  Jarcho JM, Feier NA, Labus JS, Naliboff B, Smith SR, Hong JY, Colloca L, Tillisch K, Mandelkern MA, Mayer EA, London ED. Placebo analgesia: Self-report measures and preliminary evidence of cortical dopamine release associated with placebo response. NeuroImage. Clinical. 2016;10:107-14. PubMed PMID: 26759785; PubMed Central PMCID: PMC4683423.

                  Jensen DM, Ohning GV, Kovacs TO, Ghassemi KA, Jutabha R, Dulai GS, Machicado GA. Doppler endoscopic probe as a guide to risk stratification and definitive hemostasis of peptic ulcer bleeding. Gastrointestinal endoscopy. 2016 January;83(1):129-36. PubMed PMID: 26318834; PubMed Central PMCID: PMC4691549.

                  Labus JS, Naliboff B, Kilpatrick L, Liu C, Ashe-McNalley C, dos Santos IR, Alaverdyan M, Woodworth D, Gupta A, Ellingson BM, Tillisch K, Mayer EA. Pain and Interoception Imaging Network (PAIN): A multimodal, multisite, brain-imaging repository for chronic somatic and visceral pain disorders. NeuroImage. 2016 January 1;124(Pt B):1232-7. PubMed PMID: 25902408; PubMed Central PMCID: PMC4627849.

                  Latorre R, Huynh J, Mazzoni M, Gupta A, Bonora E, Clavenzani P, Chang L, Mayer EA, De Giorgio R, Sternini C. Expression of the Bitter Taste Receptor, T2R38, in Enteroendocrine Cells of the Colonic Mucosa of Overweight/Obese vs. Lean Subjects. PloS one. 2016;11(2):e0147468. PubMed PMID: 26866366; PubMed Central PMCID: PMC4750998.

                  Moussaoui N, Larauche M, Biraud M, Molet J, Million M, Mayer E, Taché Y. Limited Nesting Stress Alters Maternal Behavior and In Vivo Intestinal Permeability in Male Wistar Pup Rats. PloS one. 2016;11(5):e0155037. PubMed PMID: 27149676; PubMed Central PMCID: PMC4858303.

                  Rouch JD, Scott A, Lei NY, Solorzano-Vargas RS, Wang J, Hanson EM, Kobayashi M, Lewis M, Stelzner MG, Dunn JC, Eckmann L, Martín MG. Development of Functional Microfold (M) Cells from Intestinal Stem Cells in Primary Human Enteroids. PloS one. 2016;11(1):e0148216. PubMed PMID: 26820624; PubMed Central PMCID: PMC4731053.

                  Zhou G, Yu J, Wang A, Liu SH, Sinnett-Smith J, Wu J, Sanchez R, Nemunaitis J, Ricordi C, Rozengurt E, Brunicardi FC. Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma. Current molecular medicine. 2016;16(1):83-90. PubMed PMID: 26695692; PubMed Central PMCID: PMC4994969.

                  Vuong HE, Hardi CN, Barnes S, Brecha NC. Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 December 2;35(48):15955-70. PubMed PMID: 26631476; PubMed Central PMCID: PMC4666919.

                  Kilpatrick LA, Istrin JJ, Gupta A, Naliboff BD, Tillisch K, Labus JS, Mayer EA. Sex commonalities and differences in the relationship between resilient personality and the intrinsic connectivity of the salience and default mode networks. Biological psychology. 2015 December;112:107-15. PubMed PMID: 26440126; PubMed Central PMCID: PMC5012423.

                  Phan J, Benhammou JN, Pisegna JR. Gastric Hypersecretory States: Investigation and Management. Current treatment options in gastroenterology. 2015 December;13(4):386-97. PubMed PMID: 26342486; PubMed Central PMCID: PMC4633316.

                  Stark AP, Chang HH, Jung X, Moro A, Hertzer K, Xu M, Schmidt A, Hines OJ, Eibl G. E-cadherin expression in obesity-associated, Kras-initiated pancreatic ductal adenocarcinoma in mice. Surgery. 2015 December;158(6):1564-72. PubMed PMID: 26297056; PubMed Central PMCID: PMC4637247.

                  Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of experimental medicine. 2015 November 16;212(12):2147-63. PubMed PMID: 26552708; PubMed Central PMCID: PMC4647265.

                  Chang HH, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G. Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1. American journal of physiology. Cell physiology. 2015 November 15;309(10):C639-49. PubMed PMID: 26310818; PubMed Central PMCID: PMC4652080.

                  Vu JP, Goyal D, Luong L, Oh S, Sandhu R, Norris J, Parsons W, Pisegna JR, Germano PM. PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin. American journal of physiology. Gastrointestinal and liver physiology. 2015 November 15;309(10):G816-25. PubMed PMID: 26336928; PubMed Central PMCID: PMC4652141.

                  Young SH, Rey O, Rozengurt E. Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: Impact of the highly conservative mutation Ser170Thr. Biochemical and biophysical research communications. 2015 November 6;467(1):1-6. PubMed PMID: 26431875; PubMed Central PMCID: PMC4613767.

                  Rodriguez JA, Huerta-Yepez S, Law IK, Baay-Guzman GJ, Tirado-Rodriguez B, Hoffman JM, Iliopoulos D, Hommes DW, Verspaget HW, Chang L, Pothoulakis C, Baritaki S. Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling. Cellular and molecular gastroenterology and hepatology. 2015 November 1;1(6):610-630. PubMed PMID: 26495412; PubMed Central PMCID: PMC4610032.

                  Vuong HE, Pérez de Sevilla Müller L, Hardi CN, McMahon DG, Brecha NC. Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines. Neuroscience. 2015 October 29;307:319-37. PubMed PMID: 26335381; PubMed Central PMCID: PMC4603663.

                  Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D. MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice. Gastroenterology. 2015 October;149(4):981-92.e11. PubMed PMID: 26055138; PubMed Central PMCID: PMC4584179.

                  Fang K, Sideri A, Law IK, Bakirtzi K, Polytarchou C, Iliopoulos D, Pothoulakis C. Identification of a novel substance P (SP)-neurokinin-1 receptor (NK-1R) microRNA-221-5p inflammatory network in human colonic epithelial cells. Cellular and molecular gastroenterology and hepatology. 2015 September 1;1(5):503-515. PubMed PMID: 26645045; PubMed Central PMCID: PMC4669978.

                  Hubbard CS, Hong J, Jiang Z, Ebrat B, Suyenobu B, Smith S, Heendeniya N, Naliboff BD, Tillisch K, Mayer EA, Labus JS. Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 September;27(9):1282-94. PubMed PMID: 26087779; PubMed Central PMCID: PMC4550526.

                  Cherukuri DP, Deignan JL, Das K, Grody WW, Herschman H. Instability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma. Molecular oncology. 2015 August;9(7):1252-8. PubMed PMID: 25817443; PubMed Central PMCID: PMC4523444.

                  Irimia A, Labus JS, Torgerson CM, Van Horn JD, Mayer EA. Altered viscerotopic cortical innervation in patients with irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 August;27(8):1075-81. PubMed PMID: 25952540; PubMed Central PMCID: PMC4520752.

                  Kaunitz JD. The Discovery of PCR: ProCuRement of Divine Power. Digestive diseases and sciences. 2015 August;60(8):2230-1. PubMed PMID: 26077976; PubMed Central PMCID: PMC4501591.

                  Kobayashi M, Lei NY, Wang Q, Wu BM, Dunn JC. Orthogonally oriented scaffolds with aligned fibers for engineering intestinal smooth muscle. Biomaterials. 2015 August;61:75-84. PubMed PMID: 26001072; PubMed Central PMCID: PMC4464968.

                  Labus JS, Van Horn JD, Gupta A, Alaverdyan M, Torgerson C, Ashe-McNalley C, Irimia A, Hong JY, Naliboff B, Tillisch K, Mayer EA. Multivariate morphological brain signatures predict patients with chronic abdominal pain from healthy control subjects. Pain. 2015 August;156(8):1545-54. PubMed PMID: 25906347; PubMed Central PMCID: PMC4504800.

                  O'Mahony F, Wroblewski K, O'Byrne SM, Jiang H, Clerkin K, Benhammou J, Blaner WS, Beaven SW. Liver X receptors balance lipid stores in hepatic stellate cells through Rab18, a retinoid responsive lipid droplet protein. Hepatology (Baltimore, Md.). 2015 August;62(2):615-26. PubMed PMID: 25482505; PubMed Central PMCID: PMC4458237.

                  Tuominen I, Beaven SW. Intestinal farnesoid X receptor puts a fresh coat of wax on fatty liver. Hepatology (Baltimore, Md.). 2015 August;62(2):646-8. PubMed PMID: 25998695; PubMed Central PMCID: PMC4523235.

                  Law IK, Bakirtzi K, Polytarchou C, Oikonomopoulos A, Hommes D, Iliopoulos D, Pothoulakis C. Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis. Gut. 2015 July;64(7):1095-104. PubMed PMID: 25112884; PubMed Central PMCID: PMC4422787.

                  Lugea A, Waldron RT, Pandol SJ. Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2015 July;15(4 Suppl):S1-5. PubMed PMID: 25736240; PubMed Central PMCID: PMC4515411.

                  Stengel A, Karasawa H, Taché Y. The role of brain somatostatin receptor 2 in the regulation of feeding and drinking behavior. Hormones and behavior. 2015 July;73:15-22. PubMed PMID: 26026616; PubMed Central PMCID: PMC4546908.

                  Sanmiguel C, Gupta A, Mayer EA. Gut Microbiome and Obesity: A Plausible Explanation for Obesity. Current obesity reports. 2015 June;4(2):250-61. PubMed PMID: 26029487; PubMed Central PMCID: PMC4443745.

                  Vu JP, Larauche M, Flores M, Luong L, Norris J, Oh S, Liang LJ, Waschek J, Pisegna JR, Germano PM. Regulation of Appetite, Body Composition, and Metabolic Hormones by Vasoactive Intestinal Polypeptide (VIP). Journal of molecular neuroscience : MN. 2015 June;56(2):377-87. PubMed PMID: 25904310; PubMed Central PMCID: PMC4458420.

                  Gupta A, Rapkin AJ, Gill Z, Kilpatrick L, Fling C, Stains J, Masghati S, Tillisch K, Mayer EA, Labus JS. Disease-related differences in resting-state networks: a comparison between localized provoked vulvodynia, irritable bowel syndrome, and healthy control subjects. Pain. 2015 May;156(5):809-19. PubMed PMID: 25735001; PubMed Central PMCID: PMC4402252.

                  Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D. A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. Inflammatory bowel diseases. 2015 May;21(5):996-1005. PubMed PMID: 25738378; PubMed Central PMCID: PMC4402238.

                  Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JC, Martin MG, Lagasse E, Zhang L, Yu J. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Scientific reports. 2015 April 10;5:8566. PubMed PMID: 25858503; PubMed Central PMCID: PMC4392360.

                  Wu JX, Liu SH, Nemunaitis JJ, Brunicardi FC. Liposomal insulin promoter-thymidine kinase gene therapy followed by ganciclovir effectively ablates human pancreatic cancer in mice. Cancer letters. 2015 April 10;359(2):206-10. PubMed PMID: 25596375; PubMed Central PMCID: PMC4336837.

                  Akiba Y, Kaunitz JD, Million M. Peripheral corticotropin-releasing factor receptor type 2 activation increases colonic blood flow through nitric oxide pathway in rats. Digestive diseases and sciences. 2015 April;60(4):858-67. PubMed PMID: 25701320; PubMed Central PMCID: PMC4501405.

                  Anselmi L, Huynh J, Duraffourd C, Jaramillo I, Vegezzi G, Saccani F, Boschetti E, Brecha NC, De Giorgio R, Sternini C. Activation of μ opioid receptors modulates inflammation in acute experimental colitis. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 April;27(4):509-23. PubMed PMID: 25690069; PubMed Central PMCID: PMC4405133.

                  Liu Z, Sun F, Braun J, McGovern DP, Piantadosi S. Multilevel regularized regression for simultaneous taxa selection and network construction with metagenomic count data. Bioinformatics (Oxford, England). 2015 April 1;31(7):1067-74. PubMed PMID: 25416747; PubMed Central PMCID: PMC4382903.

                  Marvizon JC, Walwyn W, Minasyan A, Chen W, Taylor BK. Latent sensitization: a model for stress-sensitive chronic pain. Current protocols in neuroscience. 2015 April 1;71:9.50.1-14. PubMed PMID: 25829356; PubMed Central PMCID: PMC4532319.

                  Mayer EA, Gupta A, Kilpatrick LA, Hong JY. Imaging brain mechanisms in chronic visceral pain. Pain. 2015 April;156 Suppl 1:S50-63. PubMed PMID: 25789437; PubMed Central PMCID: PMC4428597.

                  Sideri A, Stavrakis D, Bowe C, Shih DQ, Fleshner P, Arsenescu V, Arsenescu R, Turner JR, Pothoulakis C, Karagiannides I. Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1. American journal of physiology. Gastrointestinal and liver physiology. 2015 April 1;308(7):G591-604. PubMed PMID: 25591865; PubMed Central PMCID: PMC4385897.

                  Soares HP, Ming M, Mellon M, Young SH, Han L, Sinnet-Smith J, Rozengurt E. Dual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2. Molecular cancer therapeutics. 2015 April;14(4):1014-23. PubMed PMID: 25673820; PubMed Central PMCID: PMC4394038.

                  Tarling EJ, Ahn H, de Aguiar Vallim TQ. The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2. Arteriosclerosis, thrombosis, and vascular biology. 2015 April;35(4):787-95. PubMed PMID: 25593129; PubMed Central PMCID: PMC4376635.

                  Gukovsky I, Gukovskaya AS. Impaired autophagy triggers chronic pancreatitis: lessons from pancreas-specific atg5 knockout mice. Gastroenterology. 2015 March;148(3):501-5. PubMed PMID: 25613315; PubMed Central PMCID: PMC4443443.

                  Liu Y, Ji H, Zhang Y, Shen X, Gao F, He X, Li GA, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury. Journal of hepatology. 2015 March;62(3):563-72. PubMed PMID: 25450716; PubMed Central PMCID: PMC4336640.

                  Sakanaka T, Inoue T, Yorifuji N, Iguchi M, Fujiwara K, Narabayashi K, Kakimoto K, Nouda S, Okada T, Kuramoto T, Ishida K, Abe Y, Takeuchi T, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. The effects of a TGR5 agonist and a dipeptidyl peptidase IV inhibitor on dextran sulfate sodium-induced colitis in mice. Journal of gastroenterology and hepatology. 2015 March;30 Suppl 1:60-5. PubMed PMID: 25827806; PubMed Central PMCID: PMC4874188.

                  Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. The Journal of biological chemistry. 2015 February 27;290(9):5566-81. PubMed PMID: 25468909; PubMed Central PMCID: PMC4342471.

                  Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. Septin dynamics are essential for exocytosis. The Journal of biological chemistry. 2015 February 27;290(9):5280-97. PubMed PMID: 25575596; PubMed Central PMCID: PMC4342448.

                  Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell metabolism. 2015 February 3;21(2):334-46. PubMed PMID: 25651185; PubMed Central PMCID: PMC4349439.

                  de Aguiar Vallim TQ, Tarling EJ, Ahn H, Hagey LR, Romanoski CE, Lee RG, Graham MJ, Motohashi H, Yamamoto M, Edwards PA. MAFG is a transcriptional repressor of bile acid synthesis and metabolism. Cell metabolism. 2015 February 3;21(2):298-310. PubMed PMID: 25651182; PubMed Central PMCID: PMC4317590.

                  Bromley EG, May FP, Federer L, Spiegel BM, van Oijen MG. Explaining persistent under-use of colonoscopic cancer screening in African Americans: a systematic review. Preventive medicine. 2015 February;71:40-8. PubMed PMID: 25481094; PubMed Central PMCID: PMC4329030.

                  Kaji I, Iwanaga T, Watanabe M, Guth PH, Engel E, Kaunitz JD, Akiba Y. SCFA transport in rat duodenum. American journal of physiology. Gastrointestinal and liver physiology. 2015 February 1;308(3):G188-97. PubMed PMID: 25394661; PubMed Central PMCID: PMC4312951.

                  Nguyen AH, Toste PA, Farrell JJ, Clerkin BM, Williams J, Muthusamy VR, Watson RR, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Current recommendations for surveillance and surgery of intraductal papillary mucinous neoplasms may overlook some patients with cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2015 February;19(2):258-65. PubMed PMID: 25373706; PubMed Central PMCID: PMC4305480.

                  Tan YV, Abad C, Wang Y, Lopez R, Waschek J. VPAC2 (vasoactive intestinal peptide receptor type 2) receptor deficient mice develop exacerbated experimental autoimmune encephalomyelitis with increased Th1/Th17 and reduced Th2/Treg responses. Brain, behavior, and immunity. 2015 February;44:167-175. PubMed PMID: 25305591; PubMed Central PMCID: PMC4275378.

                  Taché Y, Million M. Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia. Journal of neurogastroenterology and motility. 2015 January 31;21(1):8-24. PubMed PMID: 25611064; PubMed Central PMCID: PMC4288101.

                  Coveleskie K, Gupta A, Kilpatrick LA, Mayer ED, Ashe-McNalley C, Stains J, Labus JS, Mayer EA. Altered functional connectivity within the central reward network in overweight and obese women. Nutrition & diabetes. 2015 January 19;5:e148. PubMed PMID: 25599560; PubMed Central PMCID: PMC4314578.

                  Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology. 2015 January 15;475:46-55. PubMed PMID: 25462345; PubMed Central PMCID: PMC4284078.

                  Abad C, Cheung-Lau G, Coûté-Monvoisin AC, Waschek JA. Vasoactive intestinal peptide-deficient mice exhibit reduced pathology in trinitrobenzene sulfonic acid-induced colitis. Neuroimmunomodulation. 2015;22(3):203-12. PubMed PMID: 25301381; PubMed Central PMCID: PMC4297532.

                  Bradesi S, Karagiannides I, Bakirtzi K, Joshi SM, Koukos G, Iliopoulos D, Pothoulakis C, Mayer EA. Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat. PloS one. 2015;10(7):e0130938. PubMed PMID: 26222740; PubMed Central PMCID: PMC4519289.

                  Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA. Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor. Journal of Alzheimer's disease : JAD. 2015;43(3):967-76. PubMed PMID: 25125464; PubMed Central PMCID: PMC4258165.

                  Chen R, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM, Maitra A, Brentnall TA. Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. Laboratory investigation; a journal of technical methods and pathology. 2015 January;95(1):43-55. PubMed PMID: 25347153; PubMed Central PMCID: PMC4281293.

                  Cheng M, Ho S, Yoo JH, Tran DH, Bakirtzi K, Su B, Tran DH, Kubota Y, Ichikawa R, Koon HW. Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts. Clinical and experimental gastroenterology. 2015;8:13-29. PubMed PMID: 25565877; PubMed Central PMCID: PMC4274046.

                  Gupta A, Mayer EA, Sanmiguel CP, Van Horn JD, Woodworth D, Ellingson BM, Fling C, Love A, Tillisch K, Labus JS. Patterns of brain structural connectivity differentiate normal weight from overweight subjects. NeuroImage. Clinical. 2015;7:506-17. PubMed PMID: 25737959; PubMed Central PMCID: PMC4338207.

                  Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 January 1;21(1):157-65. PubMed PMID: 25348515; PubMed Central PMCID: PMC4286535.

                  Khalil HA, Lei NY, Nie W, Lewis MS, Stelzner MG, Martín MG, Dunn JC, Yoo J. Primary Myofibroblasts Maintain Short-Term Viability following Submucosal Injection in Syngeneic, Immune-Competent Mice Utilizing Murine Colonoscopy. PloS one. 2015;10(5):e0127258. PubMed PMID: 26016485; PubMed Central PMCID: PMC4445916.

                  Kutch JJ, Yani MS, Asavasopon S, Kirages DJ, Rana M, Cosand L, Labus JS, Kilpatrick LA, Ashe-McNalley C, Farmer MA, Johnson KA, Ness TJ, Deutsch G, Harris RE, Apkarian AV, Clauw DJ, Mackey SC, Mullins C, Mayer EA. Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study. NeuroImage. Clinical. 2015;8:493-502. PubMed PMID: 26106574; PubMed Central PMCID: PMC4474411.

                  Law IK, Pothoulakis C. MicroRNA-133α regulates neurotensin-associated colonic inflammation in colonic epithelial cells and experimental colitis. RNA & disease (Houston, Tex.). 2015;2(1). PubMed PMID: 26005712; PubMed Central PMCID: PMC4441413.

                  Li Y, Go VL, Sarkar FH. The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome. Pancreas. 2015 January;44(1):1-10. PubMed PMID: 25493373; PubMed Central PMCID: PMC4264839.

                  Martinez L, Ermolova NV, Ishikawa TO, Stout DB, Herschman HR, Spencer MJ. A reporter mouse for optical imaging of inflammation in mdx muscles. Skeletal muscle. 2015;5:15. PubMed PMID: 25949789; PubMed Central PMCID: PMC4422315.

                  Marzagalli R, Scuderi S, Drago F, Waschek JA, Castorina A. Emerging Role of PACAP as a New Potential Therapeutic Target in Major Diabetes Complications. International journal of endocrinology. 2015;2015:160928. PubMed PMID: 26074958; PubMed Central PMCID: PMC4446501.

                  McGowan I, Anton PA, Elliott J, Cranston RD, Duffill K, Althouse AD, Hawkins KL, De Rosa SC. Exploring the feasibility of multi-site flow cytometric processing of gut associated lymphoid tissue with centralized data analysis for multi-site clinical trials. PloS one. 2015;10(5):e0126454. PubMed PMID: 26010577; PubMed Central PMCID: PMC4444258.

                  Mulak A, Larauche M, Biraud M, Million M, Rivier J, Taché Y. Selective agonists of somatostatin receptor subtype 1 or 2 injected peripherally induce antihyperalgesic effect in two models of visceral hypersensitivity in mice. Peptides. 2015 January;63:71-80. PubMed PMID: 25451334; PubMed Central PMCID: PMC4385413.

                  Orand A, Gupta A, Shih W, Presson AP, Hammer C, Niesler B, Heendeniya N, Mayer EA, Chang L. Catecholaminergic Gene Polymorphisms Are Associated with GI Symptoms and Morphological Brain Changes in Irritable Bowel Syndrome. PloS one. 2015;10(8):e0135910. PubMed PMID: 26288143; PubMed Central PMCID: PMC4546052.

                  Taché Y. Corticotrophin-releasing factor 1 activation in the central amygdale and visceral hyperalgesia. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2015 January;27(1):1-6. PubMed PMID: 25557223; PubMed Central PMCID: PMC4389773.

                  Wang L, Mogami S, Yakabi S, Karasawa H, Yamada C, Yakabi K, Hattori T, Taché Y. Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito. PloS one. 2015;10(9):e0139325. PubMed PMID: 26421719; PubMed Central PMCID: PMC4589401.

                  Wang Y, Yan C, Liu L, Wang W, Du H, Fan W, Lutfy K, Jiang M, Friedman TC, Liu Y. 11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue. American journal of physiology. Endocrinology and metabolism. 2015 January 1;308(1):E84-95. PubMed PMID: 25389364; PubMed Central PMCID: PMC4281684.

                  Yoo JH, Ho S, Tran DH, Cheng M, Bakirtzi K, Kukota Y, Ichikawa R, Su B, Tran DH, Hing TC, Chang I, Shih DQ, Issacson RE, Gallo RL, Fiocchi C, Pothoulakis C, Koon HW. Anti-fibrogenic effects of the anti-microbial peptide cathelicidin in murine colitis-associated fibrosis. Cellular and molecular gastroenterology and hepatology. 2015 January;1(1):55-74.e1. PubMed PMID: 25729764; PubMed Central PMCID: PMC4338438.

                  Zhu J, Lu T, Yue S, Shen X, Gao F, Busuttil RW, Kupiec-Weglinski JW, Xia Q, Zhai Y. Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation. Transplantation. 2015 January;99(1):48-55. PubMed PMID: 25340604; PubMed Central PMCID: PMC4272660.

                  Akiba Y, Kaunitz JD. Prostaglandin pathways in duodenal chemosensing. Journal of gastroenterology and hepatology. 2014 December;29 Suppl 4:93-8. PubMed PMID: 25521740; PubMed Central PMCID: PMC4451058.

                  Bagarinao E, Johnson KA, Martucci KT, Ichesco E, Farmer MA, Labus J, Ness TJ, Harris R, Deutsch G, Apkarian AV, Mayer EA, Clauw DJ, Mackey S. Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network study. Pain. 2014 December;155(12):2502-9. PubMed PMID: 25242566; PubMed Central PMCID: PMC4504202.

                  Buzzanco A, Gomez A, Rodriguez E, French BA, Tillman BA, Chang S, Ganapathy E, Junrungsee S, Zarrinpar A, Agopian VG, Naini BV, French SW Jr, French SW Sr. Digital quantitation of HCC-associated stem cell markers and protein quality control factors using tissue arrays of human liver sections. Experimental and molecular pathology. 2014 December;97(3):399-410. PubMed PMID: 25218810; PubMed Central PMCID: PMC4262606.

                  Donahue TR, Nguyen AH, Moughan J, Li L, Tatishchev S, Toste P, Farrell JJ. Stromal microRNA-21 levels predict response to 5-fluorouracil in patients with pancreatic cancer. Journal of surgical oncology. 2014 December;110(8):952-9. PubMed PMID: 25132574; PubMed Central PMCID: PMC4232442.

                  Ji H, Liu Y, Zhang Y, Shen XD, Gao F, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW. T-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury. Hepatology (Baltimore, Md.). 2014 December;60(6):2052-2064. PubMed PMID: 25066922; PubMed Central PMCID: PMC4396987.

                  Karasawa H, Pietra C, Giuliano C, Garcia-Rubio S, Xu X, Yakabi S, Taché Y, Wang L. New ghrelin agonist, HM01 alleviates constipation and L-dopa-delayed gastric emptying in 6-hydroxydopamine rat model of Parkinson's disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2014 December;26(12):1771-82. PubMed PMID: 25327342; PubMed Central PMCID: PMC4457321.

                  Stengel A, Taché Y. Brain peptides and the modulation of postoperative gastric ileus. Current opinion in pharmacology. 2014 December;19:31-7. PubMed PMID: 24999843; PubMed Central PMCID: PMC4254047.

                  Wagner JP, Sullins VF, Dunn JC. Skin-derived precursors generate enteric-type neurons in aganglionic jejunum. Journal of pediatric surgery. 2014 December;49(12):1809-14. PubMed PMID: 25487489; PubMed Central PMCID: PMC4261145.

                  Wagner JP, Sullins VF, Khalil HA, Dunn JC. A durable model of Hirschsprung's colon. Journal of pediatric surgery. 2014 December;49(12):1804-8. PubMed PMID: 25487488; PubMed Central PMCID: PMC4261142.

                  Hong C, Marshall SM, McDaniel AL, Graham M, Layne JD, Cai L, Scotti E, Boyadjian R, Kim J, Chamberlain BT, Tangirala RK, Jung ME, Fong L, Lee R, Young SG, Temel RE, Tontonoz P. The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice. Cell metabolism. 2014 November 4;20(5):910-8. PubMed PMID: 25440061; PubMed Central PMCID: PMC4261644.

                  Tong M, Jacobs JP, McHardy IH, Braun J. Sampling of intestinal microbiota and targeted amplification of bacterial 16S rRNA genes for microbial ecologic analysis. Current protocols in immunology. 2014 November 3;107:7.41.1-11. PubMed PMID: 25367129; PubMed Central PMCID: PMC4457454.

                  Balaji K, French CT, Miller JF, Colicelli J. The RAB5-GEF function of RIN1 regulates multiple steps during Listeria monocytogenes infection. Traffic (Copenhagen, Denmark). 2014 November;15(11):1206-18. PubMed PMID: 25082076; PubMed Central PMCID: PMC4282165.

                  Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR. Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer. Molecular cancer research : MCR. 2014 November;12(11):1677-88. PubMed PMID: 25063587; PubMed Central PMCID: PMC4233191.

                  Rozengurt E, Soares HP, Sinnet-Smith J. Suppression of feedback loops mediated by PI3K/mTOR induces multiple overactivation of compensatory pathways: an unintended consequence leading to drug resistance. Molecular cancer therapeutics. 2014 November;13(11):2477-88. PubMed PMID: 25323681; PubMed Central PMCID: PMC4222988.

                  Shih DQ, Zheng L, Zhang X, Zhang H, Kanazawa Y, Ichikawa R, Wallace KL, Chen J, Pothoulakis C, Koon HW, Targan SR. Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis. Mucosal immunology. 2014 November;7(6):1492-503. PubMed PMID: 24850426; PubMed Central PMCID: PMC4205266.

                  Spiegel BM, Hays RD, Bolus R, Melmed GY, Chang L, Whitman C, Khanna PP, Paz SH, Hays T, Reise S, Khanna D. Development of the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) gastrointestinal symptom scales. The American journal of gastroenterology. 2014 November;109(11):1804-14. PubMed PMID: 25199473; PubMed Central PMCID: PMC4285435.

                  Hong JY, Kilpatrick LA, Labus JS, Gupta A, Katibian D, Ashe-McNalley C, Stains J, Heendeniya N, Smith SR, Tillisch K, Naliboff B, Mayer EA. Sex and disease-related alterations of anterior insula functional connectivity in chronic abdominal pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2014 October 22;34(43):14252-9. PubMed PMID: 25339739; PubMed Central PMCID: PMC4205551.

                  Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Molecular cancer therapeutics. 2014 October;13(10):2303-14. PubMed PMID: 25082960; PubMed Central PMCID: PMC4188417.

                  Itoh Y, Arnold AP. X chromosome regulation of autosomal gene expression in bovine blastocysts. Chromosoma. 2014 October;123(5):481-9. PubMed PMID: 24817096; PubMed Central PMCID: PMC4170013.

                  Ruegger PM, Clark RT, Weger JR, Braun J, Borneman J. Improved resolution of bacteria by high throughput sequence analysis of the rRNA internal transcribed spacer. Journal of microbiological methods. 2014 October;105:82-7. PubMed PMID: 25034229; PubMed Central PMCID: PMC4160368.

                  Arnold AP. Conceptual frameworks and mouse models for studying sex differences in physiology and disease: why compensation changes the game. Experimental neurology. 2014 September;259:2-9. PubMed PMID: 24509348; PubMed Central PMCID: PMC4125548.

                  Im E, Jung J, Pothoulakis C, Rhee SH. Disruption of Pten speeds onset and increases severity of spontaneous colitis in Il10(-/-) mice. Gastroenterology. 2014 September;147(3):667-679.e10. PubMed PMID: 24882466; PubMed Central PMCID: PMC4143453.

                  Liu Y, Yuan J, Tan T, Jia W, Lugea A, Mareninova O, Waldron RT, Pandol SJ. Genetic inhibition of protein kinase Cε attenuates necrosis in experimental pancreatitis. American journal of physiology. Gastrointestinal and liver physiology. 2014 September 1;307(5):G550-63. PubMed PMID: 25035113; PubMed Central PMCID: PMC4154116.

                  Costes S, Butler PC. Insulin-degrading enzyme inhibition, a novel therapy for type 2 diabetes?. Cell metabolism. 2014 August 5;20(2):201-3. PubMed PMID: 25100059; PubMed Central PMCID: PMC4144405.

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                  Ming M, Sinnett-Smith J, Wang J, Soares HP, Young SH, Eibl G, Rozengurt E. Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. PloS one. 2014;9(12):e114573. PubMed PMID: 25493642; PubMed Central PMCID: PMC4262417.

                  Richardson-Harman N, Hendrix CW, Bumpus NN, Mauck C, Cranston RD, Yang K, Elliott J, Tanner K, McGowan I, Kashuba A, Anton PA. Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study. PloS one. 2014;9(10):e111507. PubMed PMID: 25350130; PubMed Central PMCID: PMC4211741.

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                  Stengel A, Taché Y. CRF and urocortin peptides as modulators of energy balance and feeding behavior during stress. Frontiers in neuroscience. 2014;8:52. PubMed PMID: 24672423; PubMed Central PMCID: PMC3957495.

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                  Vegezzi G, Anselmi L, Huynh J, Barocelli E, Rozengurt E, Raybould H, Sternini C. Diet-induced regulation of bitter taste receptor subtypes in the mouse gastrointestinal tract. PloS one. 2014;9(9):e107732. PubMed PMID: 25238152; PubMed Central PMCID: PMC4169553.

                  Vu JP, Million M, Larauche M, Luong L, Norris J, Waschek JA, Pothoulakis C, Pisegna JR, Germano PM. Inhibition of vasoactive intestinal polypeptide (VIP) induces resistance to dextran sodium sulfate (DSS)-induced colitis in mice. Journal of molecular neuroscience : MN. 2014 January;52(1):37-47. PubMed PMID: 24395090; PubMed Central PMCID: PMC4114158.

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                  Ke B, Shen XD, Zhang Y, Ji H, Gao F, Yue S, Kamo N, Zhai Y, Yamamoto M, Busuttil RW, Kupiec-Weglinski JW. KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants. Journal of hepatology. 2013 December;59(6):1200-7. PubMed PMID: 23867319; PubMed Central PMCID: PMC4524560.

                  Marcus EA, Vagin O, Tokhtaeva E, Sachs G, Scott DR. Helicobacter pylori impedes acid-induced tightening of gastric epithelial junctions. American journal of physiology. Gastrointestinal and liver physiology. 2013 November 15;305(10):G731-9. PubMed PMID: 23989011; PubMed Central PMCID: PMC3840231.

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                  Dawson DW, Hertzer K, Moro A, Donald G, Chang HH, Go VL, Pandol SJ, Lugea A, Gukovskaya AS, Li G, Hines OJ, Rozengurt E, Eibl G. High-fat, high-calorie diet promotes early pancreatic neoplasia in the conditional KrasG12D mouse model. Cancer prevention research (Philadelphia, Pa.). 2013 October;6(10):1064-73. PubMed PMID: 23943783; PubMed Central PMCID: PMC3835151.

                  Connolly L, Coveleskie K, Kilpatrick LA, Labus JS, Ebrat B, Stains J, Jiang Z, Tillisch K, Raybould HE, Mayer EA. Differences in brain responses between lean and obese women to a sweetened drink. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2013 July;25(7):579-e460. PubMed PMID: 23566308; PubMed Central PMCID: PMC4114731.

                  Kisfalvi K, Moro A, Sinnett-Smith J, Eibl G, Rozengurt E. Metformin inhibits the growth of human pancreatic cancer xenografts. Pancreas. 2013 July;42(5):781-5. PubMed PMID: 23462329; PubMed Central PMCID: PMC3681894.

                  Sinnett-Smith J, Kisfalvi K, Kui R, Rozengurt E. Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK. Biochemical and biophysical research communications. 2013 January 4;430(1):352-7. PubMed PMID: 23159620; PubMed Central PMCID: PMC3545113.

                  Waldron RT, Innamorati G, Torres-Marquez ME, Sinnett-Smith J, Rozengurt E. Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq. Cellular signalling. 2012 April;24(4):914-21. PubMed PMID: 22227248; PubMed Central PMCID: PMC3286641.

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                  Kisfalvi K, Hurd C, Guha S, Rozengurt E. Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells. Journal of cellular physiology. 2010 May;223(2):309-16. PubMed PMID: 20082306; PubMed Central PMCID: PMC2888293.

                  Rozengurt E, Sinnett-Smith J, Kisfalvi K. Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2010 May 1;16(9):2505-11. PubMed PMID: 20388847; PubMed Central PMCID: PMC2862089.

                  Weinberg BM, Spiegel BM, Tomlinson JS, Farrell JJ. Asymptomatic pancreatic cystic neoplasms: maximizing survival and quality of life using Markov-based clinical nomograms. Gastroenterology. 2010 February;138(2):531-40. PubMed PMID: 19818780; PubMed Central PMCID: PMC2949077.

                  Torres-Marquez E, Sinnett-Smith J, Guha S, Kui R, Waldron RT, Rey O, Rozengurt E. CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway. Biochemical and biophysical research communications. 2010 January 1;391(1):63-8. PubMed PMID: 19896460; PubMed Central PMCID: PMC2812606.

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                  Jiang X, Sinnett-Smith J, Rozengurt E. Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. Biochemical and biophysical research communications. 2009 September 25;387(3):521-4. PubMed PMID: 19615971; PubMed Central PMCID: PMC2754135.

                  Kisfalvi K, Eibl G, Sinnett-Smith J, Rozengurt E. Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer research. 2009 August 15;69(16):6539-45. PubMed PMID: 19679549; PubMed Central PMCID: PMC2753241.

                  Spiegel BM, Farid M, van Oijen MG, Laine L, Howden CW, Esrailian E. Adherence to best practice guidelines in dyspepsia: a survey comparing dyspepsia experts, community gastroenterologists and primary-care providers. Alimentary pharmacology & therapeutics. 2009 April 15;29(8):871-81. PubMed PMID: 19183152; PubMed Central PMCID: PMC2953468.

                  Desai AA, Bolus R, Nissenson A, Chertow GM, Bolus S, Solomon MD, Khawar OS, Talley J, Spiegel BM. Is there "cherry picking" in the ESRD Program? Perceptions from a Dialysis Provider Survey. Clinical journal of the American Society of Nephrology : CJASN. 2009 April;4(4):772-7. PubMed PMID: 19339407; PubMed Central PMCID: PMC2666440.

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